WO2003092808A1 - Device in connection with pacers - Google Patents

Device in connection with pacers Download PDF

Info

Publication number
WO2003092808A1
WO2003092808A1 PCT/SE2003/000513 SE0300513W WO03092808A1 WO 2003092808 A1 WO2003092808 A1 WO 2003092808A1 SE 0300513 W SE0300513 W SE 0300513W WO 03092808 A1 WO03092808 A1 WO 03092808A1
Authority
WO
WIPO (PCT)
Prior art keywords
connector
tubular connector
contact pin
housing
transparent device
Prior art date
Application number
PCT/SE2003/000513
Other languages
French (fr)
Inventor
Martin HÖRNFELDT
Eva Skoog Andersson
Original Assignee
St Jude Medical Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St Jude Medical Ab filed Critical St Jude Medical Ab
Priority to DE60327759T priority Critical patent/DE60327759D1/en
Priority to US10/514,969 priority patent/US20060041282A1/en
Priority to EP03747549A priority patent/EP1501599B1/en
Publication of WO2003092808A1 publication Critical patent/WO2003092808A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A61N1/3752—Details of casing-lead connections

Definitions

  • the present invention relates to pacer housings and more particularly to those parts of the housing intended for connection to the electrode leads.
  • Implantable pacers normally comprise a pacer housing (also called can) containing electronic circuitry and a unit for electric power as well as different electrodes which are connected to the interior parts in the pacer housing and which are to be implanted in or in the vicinity of the heart.
  • the electrodes are connected to the pacer by means of leads.
  • the internal parts of the pacers have to be well protected against the internal environment, especially the body fluids in the body for a long period of time, which places strict requirements on all entries into the interior of the can and especially on the connections of the leads to the housing. At the same time it should be possible to disconnect the pacer from the implanted leads for replacement or servicing of the pacer.
  • the connective parts of the pacer and the leads have largely been standardized so as to encompass a relatively deep female socket comprising a number of contact surfaces whereas the leads are provided with a male part comprising one or several corresponding peripheral, generally circular contact surfaces.
  • the connective part of the pacer housing containing the female socket is made of a transparent material, normally of epoxy resin, which is molded onto the housing and onto contacts extending outwardly from the housing.
  • the male part of the leads is normally locked by means of set screws, although other fastening means have been envisaged.
  • the positioning and alignment of the different contact surfaces and of the fastening means or metallic threads for the set screws prior to the molding of the connective part is however complicated and the delay in the manufacturing process incurred by the curing of the epoxy resin is considerable. It would thus be desirable if the molding procedure could be dispensed with. It should however be noted that the molded connective part allows visible confirmation that the lead connector is adequately inserted.
  • the use of different materials however set high standards in regard of precision and durability of the component parts as well as on the assembly procedure thereof. This is especially important since the interior sockets must meet very high standards regarding the integrity of the interior of the pacer housing during long times of implantation in a demanding environment .
  • WO 00/12174 which is incorporated by reference descibe a tubular connector which is welded in both ends to the pacer encapsulation.
  • a tubular connector as disclosed in WO 00/12174 is used in an implantable pacemaker.
  • the connector is designed such that a part of the most proximal lead contact pin extends beyond the second opening of said tubular connector when the lead is adequately inserted in the tubular connector.
  • a transparent device is glued on the pacemaker so that the portion of the lead contact pin that extends beyond the second opening of the tubular connector is at least partly surrounded by the transparent device. This allows for a visual confirmation that the lead is adequately inserted into the connector.
  • a molding process on the pacemaker housing will however not be necessary.
  • a prefabricated transparent device is e.g. glued to a pacer housing comprising a tubular connector which is open in both ends in accordance with the appended main claim. Preferred embodiments are set forth in the dependent claims.
  • Fig 1 shows a conventional pacer housing with a transparent, molded connective part
  • Fig 2 shows a lead with a male connective part
  • Fig 3 shows a preferred embodiment in in accordance with the present invention which provides visual confirmation that the electrode lead is adequately inserted into the pulse generator.
  • Fig 4 shows a preferred embodiment in which a different design of the tubular connector is showed.
  • Fig 5 shows an embodiment in which the pacemaker is built using functional modules that also contribute to the outer enclosure of the pacemaker.
  • Fig 6 shows an embodiment which provides visual confirmation that the electrode lead is adequately inserted into the pulse generator combined with a locking mechanism. Detailed description of preferred embodiments of the invention.
  • Fig 1 illustrates a conventional pacer housing 1 having a molded, transparent connective part 2.
  • the connective part 2 includes a female socket 3.
  • the inner end of the socket 3 is provided with a longitudinal bore 7 having a relatively small diameter.
  • the bore 7 is provided with a contact surface 4 adjacent to which threads 5 for a set or lock screw are located in a bore 6 oriented orthogonally relative to the female socket.
  • the housing is hermetically sealed also in relation to the molded part 2 and the contact between the interior electronics and the contact surface 4 is achieved by means of a feed-through.
  • the feed-through comprises a ceramic plug, typically made of alumina, into which one or more leads have been soldered. This lead is bonded (e.g. ultrasonically welded) to the electronics and to the contact surface 4.
  • the ceramic plug is soldered or brazed by means of gold into a sleeve made of titanium. This operation may be made at any time before the assembly of the pacer housing.
  • the sleeve is welded into an opening in the housing in a sealing manner during the assembly of the pacer housing that normally consists of two halves. Before the connective part is molded onto the housing, these halves are welded together and sealed.
  • Fig 2 illustrates a lead 15 comprising a proximal connecting plug 10 and a distal, transvenous, intracardial electrode 16 as well as an attachment means 17 for suturing the proximal end of the lead in the body of the patient.
  • the connecting plug 10 is designed to be received in the socket 3 and the end thereof is provided with a longitudinally projecting contact pin 11 as well as a cylindrical body provided with sealing rings 12, 13, 14 intended to engage and seal against the corresponding inner cylindrical surface of the female socket 3.
  • the shape of the pin 11 corresponds to the shape of the bore 7.
  • Fig 3 shows an embodiment of the invention which consequently allows for a visual confirmation that the male connector plug 10 is adequately inserted into the pulse generator.
  • the design of the tubular connector 29 is similar as disclosed in WO 00/12174.
  • the tubular connector 29 is in this embodiment shorter to allow the contact pin to extend beyond the second opening 18 of the tubular connector 29.
  • a transparent component 19 is mounted on the pulse generator.
  • the transparent component 19 is fixed to the pacer housing through e.g. glueing or other method.
  • the transparent component 19 comprises a cavity 20 which the contact pin 11 will enter when the connector plug 10 is adequately inserted. If the connector plug 10 is adequately inserted then the contact pin 11 is visible inside the transparent component 19.
  • the tubular connector can of course be designed in different ways, such as for instane shown in fig 4.
  • the tubular connector 29 is composed from alternating ceramic and metallic sections. The sections are brazed or soldered together using known technology.
  • the ends 21, 22 of the tubular connector are metallic and are welded to the pacemaker encapsulation 1.
  • the spring contacts used for connection to the connective surfaces of the contact pin are similar to the spring contacts used in US-A- , 93 , 366.
  • the spring contacts are located the in metallic sections 23, 24 of the tubular connector. Ceramic sections 25, 26, 27 provide the necessary insulation to separate the spring contacts from each other and from the encapsulation.
  • the pacemaker also can be designed in different ways.
  • Fig 5 shows an embodiment in which the pacemaker is constructed using functional modules which contribute to the funtion as well as to the outer enclosure of the pacemaker.
  • the pacemaker comprises at least one connector module 30, an electronics module 31 and a battery module 32.
  • the individual modules are welded together to obtain a hermetic device with one single hermetic compartment.
  • the connector module comprises a portion of the outer enclosure 33, the tubular connectors 34a, 34b, the locking mechanisms 35a, 35b, the transparent device 36 and flex circuits 37a, 37b for connection to the electronics module.
  • the locking mechanisms 35a, 35b are located at the intersection between the tubular connectors 34a, 34b and the transparent device 36.
  • Fig 6 shows an embodiment in which the transparent component 19 comprises an electrode lead locking mechanism 28.
  • the locking mechanism 28 is automatically activated when the contact pin 11 is advanced through said locking mechanism 28.
  • the retention force is significantly higher than the insertion force due to bending of a portion of a washer in the locking mechanism 28.
  • the connector means can be achieved in a simple way compared with the prior art molded connector means while still providing a visual confirmation that the lead connector pin is adequately inserted.
  • the invention is applicable to any type of tubular connector that has openings in both ends.
  • the invention is further applicable to any type of pacemaker housing that comprises a tubular connector that is welded to the pacemaker housing in both ends .
  • One important feature of the invention is that visual information that the connector plug is adequately inserted is available in device without a molded connector top.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)

Abstract

The invention relates to the electrode lead connector of a pacemaker. A tubular connector (29) is used for connection to the electrode lead contact plug (10). A transparent component (19) allows for visual confirmation that the electrode lead contact plug (10) is adequately inserted into said tubular connector (29).

Description

Device in connection with pacers
Technical field of the invention.
The present invention relates to pacer housings and more particularly to those parts of the housing intended for connection to the electrode leads.
Background of the invention.
Implantable pacers normally comprise a pacer housing (also called can) containing electronic circuitry and a unit for electric power as well as different electrodes which are connected to the interior parts in the pacer housing and which are to be implanted in or in the vicinity of the heart. The electrodes are connected to the pacer by means of leads. The internal parts of the pacers have to be well protected against the internal environment, especially the body fluids in the body for a long period of time, which places strict requirements on all entries into the interior of the can and especially on the connections of the leads to the housing. At the same time it should be possible to disconnect the pacer from the implanted leads for replacement or servicing of the pacer. The connective parts of the pacer and the leads have largely been standardized so as to encompass a relatively deep female socket comprising a number of contact surfaces whereas the leads are provided with a male part comprising one or several corresponding peripheral, generally circular contact surfaces.
At present the connective part of the pacer housing containing the female socket is made of a transparent material, normally of epoxy resin, which is molded onto the housing and onto contacts extending outwardly from the housing. The male part of the leads is normally locked by means of set screws, although other fastening means have been envisaged. The positioning and alignment of the different contact surfaces and of the fastening means or metallic threads for the set screws prior to the molding of the connective part is however complicated and the delay in the manufacturing process incurred by the curing of the epoxy resin is considerable. It would thus be desirable if the molding procedure could be dispensed with. It should however be noted that the molded connective part allows visible confirmation that the lead connector is adequately inserted.
It has been discussed that these complexities could be avoided by designing the pacer with a socket located inside the metal housing. To our knowledge this kind of sockets, sometimes termed "black holes", are not used at present.
US-A~4,934,36β and US-A-5, 32 , 311, both of which are incorporated by reference, describe two interior sockets or black holes for pacers. Both designs comprise a tubular member consisting of a number of longitudinally alternating sections made of metal respectively of insulating ceramics. An end section of metal can be welded or bonded to an opening in the pacer housing by means of a flange. The use of different materials however set high standards in regard of precision and durability of the component parts as well as on the assembly procedure thereof. This is especially important since the interior sockets must meet very high standards regarding the integrity of the interior of the pacer housing during long times of implantation in a demanding environment .
WO 00/12174 which is incorporated by reference descibe a tubular connector which is welded in both ends to the pacer encapsulation.
Short description of the inventive concept
According to the invention a tubular connector as disclosed in WO 00/12174 is used in an implantable pacemaker. The connector is designed such that a part of the most proximal lead contact pin extends beyond the second opening of said tubular connector when the lead is adequately inserted in the tubular connector. A transparent device is glued on the pacemaker so that the portion of the lead contact pin that extends beyond the second opening of the tubular connector is at least partly surrounded by the transparent device. This allows for a visual confirmation that the lead is adequately inserted into the connector. A molding process on the pacemaker housing will however not be necessary. According to the invention a prefabricated transparent device is e.g. glued to a pacer housing comprising a tubular connector which is open in both ends in accordance with the appended main claim. Preferred embodiments are set forth in the dependent claims.
Short description of the appended drawings
Fig 1 shows a conventional pacer housing with a transparent, molded connective part;
Fig 2 shows a lead with a male connective part;
Fig 3 shows a preferred embodiment in in accordance with the present invention which provides visual confirmation that the electrode lead is adequately inserted into the pulse generator.
Fig 4 shows a preferred embodiment in which a different design of the tubular connector is showed.
Fig 5 shows an embodiment in which the pacemaker is built using functional modules that also contribute to the outer enclosure of the pacemaker.
Fig 6 shows an embodiment which provides visual confirmation that the electrode lead is adequately inserted into the pulse generator combined with a locking mechanism. Detailed description of preferred embodiments of the invention.
Fig 1 illustrates a conventional pacer housing 1 having a molded, transparent connective part 2. The connective part 2 includes a female socket 3. The inner end of the socket 3 is provided with a longitudinal bore 7 having a relatively small diameter. The bore 7 is provided with a contact surface 4 adjacent to which threads 5 for a set or lock screw are located in a bore 6 oriented orthogonally relative to the female socket. The housing is hermetically sealed also in relation to the molded part 2 and the contact between the interior electronics and the contact surface 4 is achieved by means of a feed-through. The feed-through comprises a ceramic plug, typically made of alumina, into which one or more leads have been soldered. This lead is bonded (e.g. ultrasonically welded) to the electronics and to the contact surface 4. The ceramic plug is soldered or brazed by means of gold into a sleeve made of titanium. This operation may be made at any time before the assembly of the pacer housing. The sleeve is welded into an opening in the housing in a sealing manner during the assembly of the pacer housing that normally consists of two halves. Before the connective part is molded onto the housing, these halves are welded together and sealed.
Fig 2 illustrates a lead 15 comprising a proximal connecting plug 10 and a distal, transvenous, intracardial electrode 16 as well as an attachment means 17 for suturing the proximal end of the lead in the body of the patient. The connecting plug 10 is designed to be received in the socket 3 and the end thereof is provided with a longitudinally projecting contact pin 11 as well as a cylindrical body provided with sealing rings 12, 13, 14 intended to engage and seal against the corresponding inner cylindrical surface of the female socket 3. The shape of the pin 11 corresponds to the shape of the bore 7. When the plug 10 is inserted into the socket 3 the pin 11 engages the contact surface 4 and the set-screw in the bore 6 can be tightened against the pin 11 in order to securely lock the plug 10 in the socket 3. The complexities involved in holding the bores, contact surfaces and threads in position and keeping them open and free from the molding material during the molding process are evident.
For the sake of simplicity, the above prior art device has been illustrated as being unipolar. A bipolar embodiment naturally will be more complex to manufacture. The preferred embodiments of the invention described below will relate to bipolar embodiments.
Fig 3 shows an embodiment of the invention which consequently allows for a visual confirmation that the male connector plug 10 is adequately inserted into the pulse generator. The design of the tubular connector 29 is similar as disclosed in WO 00/12174. The tubular connector 29 is in this embodiment shorter to allow the contact pin to extend beyond the second opening 18 of the tubular connector 29.
A transparent component 19 is mounted on the pulse generator. The transparent component 19 is fixed to the pacer housing through e.g. glueing or other method. The transparent component 19 comprises a cavity 20 which the contact pin 11 will enter when the connector plug 10 is adequately inserted. If the connector plug 10 is adequately inserted then the contact pin 11 is visible inside the transparent component 19.
The tubular connector can of course be designed in different ways, such as for instane shown in fig 4. In this embodiment the tubular connector 29 is composed from alternating ceramic and metallic sections. The sections are brazed or soldered together using known technology. The ends 21, 22 of the tubular connector are metallic and are welded to the pacemaker encapsulation 1. The spring contacts used for connection to the connective surfaces of the contact pin are similar to the spring contacts used in US-A- , 93 , 366. The spring contacts are located the in metallic sections 23, 24 of the tubular connector. Ceramic sections 25, 26, 27 provide the necessary insulation to separate the spring contacts from each other and from the encapsulation.
The pacemaker also can be designed in different ways.
Fig 5 shows an embodiment in which the pacemaker is constructed using functional modules which contribute to the funtion as well as to the outer enclosure of the pacemaker. The pacemaker comprises at least one connector module 30, an electronics module 31 and a battery module 32. The individual modules are welded together to obtain a hermetic device with one single hermetic compartment. The connector module comprises a portion of the outer enclosure 33, the tubular connectors 34a, 34b, the locking mechanisms 35a, 35b, the transparent device 36 and flex circuits 37a, 37b for connection to the electronics module. The locking mechanisms 35a, 35b are located at the intersection between the tubular connectors 34a, 34b and the transparent device 36.
Fig 6 shows an embodiment in which the transparent component 19 comprises an electrode lead locking mechanism 28. The locking mechanism 28 is automatically activated when the contact pin 11 is advanced through said locking mechanism 28. The retention force is significantly higher than the insertion force due to bending of a portion of a washer in the locking mechanism 28.
The connector means can be achieved in a simple way compared with the prior art molded connector means while still providing a visual confirmation that the lead connector pin is adequately inserted. The invention is applicable to any type of tubular connector that has openings in both ends. The invention is further applicable to any type of pacemaker housing that comprises a tubular connector that is welded to the pacemaker housing in both ends .
One important feature of the invention is that visual information that the connector plug is adequately inserted is available in device without a molded connector top.

Claims

Claims
1. An implantable heart stimulator intended to be implanted in a human body comprising at least one tubular connector (29) having a first opening adapted to receive a heart lead connector plug (10) comprising a contact pin (11) for electrical connection between said heart lead electrode and said heart stimulator, characterized in that said tubular connector (29) has a second opening allowing said contact pin (11) to extend beyond said second opening (18) of said tubular connector (29); and in that said implantable heart stimulator comprises a transparent device (19) that allows visual confirmation that said connector plug (10) is adequately inserted; and that said transparent device at least partly surrounds the extending part of said contact pin (11) so as to allow said visual confirmation .
2. The implantable heart stimulator according to claim 1 characterized in that said transparent device (19) comprises a contact pin (11) locking mechanism (28).
3. The implantable heart stimulator according to claim 1 characterized in that said transparent device (19) is premolded. The heart stimulator according to claim 1 characterized in that said transparent device (19) is manufactured from a polymer material.
PCT/SE2003/000513 2002-04-30 2003-03-28 Device in connection with pacers WO2003092808A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE60327759T DE60327759D1 (en) 2002-04-30 2003-03-28 DEVICE IN CONNECTION WITH PACEMAKERS
US10/514,969 US20060041282A1 (en) 2002-04-30 2003-03-28 Device in connection with pacers
EP03747549A EP1501599B1 (en) 2002-04-30 2003-03-28 Device in connection with pacers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0201322-5 2002-04-30
SE0201322A SE0201322D0 (en) 2002-04-30 2002-04-30 Device in connection with pacers

Publications (1)

Publication Number Publication Date
WO2003092808A1 true WO2003092808A1 (en) 2003-11-13

Family

ID=20287745

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SE2003/000513 WO2003092808A1 (en) 2002-04-30 2003-03-28 Device in connection with pacers

Country Status (5)

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US (1) US20060041282A1 (en)
EP (1) EP1501599B1 (en)
DE (1) DE60327759D1 (en)
SE (1) SE0201322D0 (en)
WO (1) WO2003092808A1 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007027568A2 (en) * 2005-08-31 2007-03-08 Medtronic, Inc. Lead insertion visibility
EP1795225A1 (en) * 2005-12-08 2007-06-13 BIOTRONIK CRM Patent AG Housing for a medical implant
WO2008088566A1 (en) * 2007-01-18 2008-07-24 Medtronic, Inc. Internal hermetic lead connector for implantable device
WO2008088565A1 (en) * 2007-01-18 2008-07-24 Medtronic, Inc. Internal hermetic lead connector for implantable device
WO2008088567A1 (en) * 2007-01-18 2008-07-24 Medtronic, Inc. Methods of manufacturing a hermetic lead connector
EP2111258B1 (en) * 2007-01-18 2015-06-03 Medtronic, Inc. Hermetic lead connector assembly

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7764995B2 (en) * 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7567841B2 (en) * 2004-08-20 2009-07-28 Cardiac Pacemakers, Inc. Method and apparatus for delivering combined electrical and drug therapies
ATE510590T1 (en) 2005-09-29 2011-06-15 St Jude Medical IMPLANTABLE MEDICAL DEVICE WITH WELDABLE HOUSING AND HEADER

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US3908668A (en) * 1974-04-26 1975-09-30 Medtronic Inc Tissue stimulator with sealed lead connector
US4072154A (en) * 1976-05-28 1978-02-07 Cardiac Pacemakers, Inc. Sealing arrangement for heart pacer electrode leads
US4154248A (en) * 1977-05-04 1979-05-15 Medtronic, Inc. Body implantable electrical stimulator
US5507662A (en) * 1993-06-01 1996-04-16 Siemens Elema Ab Device for affixing an electrode cable to an apparatus
US5679026A (en) * 1995-12-21 1997-10-21 Ventritex, Inc. Header adapter for an implantable cardiac stimulation device
US5683433A (en) * 1995-05-17 1997-11-04 Ventritex, Inc. Implantable medical apparatus with magnifying header

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US5545189A (en) * 1995-11-02 1996-08-13 Ventritex, Inc. Case-activating switch assembly for an implantable cardiac stimulation device
US6205358B1 (en) * 1997-08-01 2001-03-20 Medtronic, Inc. Method of making ultrasonically welded, staked of swaged components in an implantable medical device
US6112121A (en) * 1998-09-09 2000-08-29 Intermedics Inc. Implantable medical device with positive indication of lead connection and connector therefor
US6505073B2 (en) * 2001-03-20 2003-01-07 Cardiac Pacemakers, Inc. Implantable medical device with full metallic case

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US3908668A (en) * 1974-04-26 1975-09-30 Medtronic Inc Tissue stimulator with sealed lead connector
US4072154A (en) * 1976-05-28 1978-02-07 Cardiac Pacemakers, Inc. Sealing arrangement for heart pacer electrode leads
US4154248A (en) * 1977-05-04 1979-05-15 Medtronic, Inc. Body implantable electrical stimulator
US5507662A (en) * 1993-06-01 1996-04-16 Siemens Elema Ab Device for affixing an electrode cable to an apparatus
US5683433A (en) * 1995-05-17 1997-11-04 Ventritex, Inc. Implantable medical apparatus with magnifying header
US5679026A (en) * 1995-12-21 1997-10-21 Ventritex, Inc. Header adapter for an implantable cardiac stimulation device

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007027568A2 (en) * 2005-08-31 2007-03-08 Medtronic, Inc. Lead insertion visibility
WO2007027568A3 (en) * 2005-08-31 2008-02-07 Medtronic Inc Lead insertion visibility
US7983754B2 (en) 2005-08-31 2011-07-19 Medtronic, Inc. Lead insertion visibility
EP1795225A1 (en) * 2005-12-08 2007-06-13 BIOTRONIK CRM Patent AG Housing for a medical implant
US7711427B2 (en) 2007-01-18 2010-05-04 Medtronis, Inc. Internal hermetic lead connector for implantable device
WO2008088567A1 (en) * 2007-01-18 2008-07-24 Medtronic, Inc. Methods of manufacturing a hermetic lead connector
WO2008088565A1 (en) * 2007-01-18 2008-07-24 Medtronic, Inc. Internal hermetic lead connector for implantable device
US7720538B2 (en) 2007-01-18 2010-05-18 Medtronic, Inc. Internal hermetic lead connector for implantable device
WO2008088566A1 (en) * 2007-01-18 2008-07-24 Medtronic, Inc. Internal hermetic lead connector for implantable device
US8131370B2 (en) 2007-01-18 2012-03-06 Medtronic, Inc Methods of manufacturing a hermetic lead connector
EP2111258B1 (en) * 2007-01-18 2015-06-03 Medtronic, Inc. Hermetic lead connector assembly
US10363424B2 (en) 2007-01-18 2019-07-30 Medtronic, Inc. Methods of manufacturing a hermetic lead connector
US11559694B2 (en) 2007-01-18 2023-01-24 Medtronic, Inc. Methods of manufacturing a hermetic lead connector

Also Published As

Publication number Publication date
SE0201322D0 (en) 2002-04-30
EP1501599B1 (en) 2009-05-27
DE60327759D1 (en) 2009-07-09
EP1501599A1 (en) 2005-02-02
US20060041282A1 (en) 2006-02-23

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