WO2003075852A3 - Antibiotic composition - Google Patents

Antibiotic composition Download PDF

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Publication number
WO2003075852A3
WO2003075852A3 PCT/US2003/007118 US0307118W WO03075852A3 WO 2003075852 A3 WO2003075852 A3 WO 2003075852A3 US 0307118 W US0307118 W US 0307118W WO 03075852 A3 WO03075852 A3 WO 03075852A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
antibiotic composition
antibiotic
products
different
different antibiotics
Prior art date
Application number
PCT/US2003/007118
Other languages
French (fr)
Other versions
WO2003075852A2 (en )
Inventor
James D Isbister
Edward M Rudnic
Jr Donald J Treacy
Sandra E Wassink
Original Assignee
Advancis Pharmaceuticals Corp
James D Isbister
Edward M Rudnic
Jr Donald J Treacy
Sandra E Wassink
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Abstract

Antibiotic products for delivering at least two different antibiotics, wherein the products are comprised of at least three or four dosage forms with different release profiles and the at least two different antibiotics are selected from specified antibiotic pairs.
PCT/US2003/007118 2000-02-24 2003-03-07 Antibiotic composition WO2003075852A3 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
US10/092,858 2002-03-07
US10/093,214 2002-03-07
US10092858 US6632453B2 (en) 2000-02-24 2002-03-07 Ciprofoxacin-metronidazole antibiotic composition
US10/093,321 2002-03-07
US10092854 US6627222B2 (en) 2000-02-24 2002-03-07 Amoxicillin-dicloxacillin antibiotic composition
US10/092,811 2002-03-07
US10/092,854 2002-03-07
US10093214 US6638532B2 (en) 2000-02-24 2002-03-07 Tetracycline—doxycycline antibiotic composition
US10092811 US6623758B2 (en) 2000-02-24 2002-03-07 Cephalosporin-metronidazole antibiotic composition
US10093321 US6610328B2 (en) 2000-02-24 2002-03-07 Amoxicillin-clarithromycin antibiotic composition

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20030714005 EP1487414A4 (en) 2002-03-07 2003-03-07 Antibiotic composition
JP2003574128A JP2005526059A (en) 2002-03-07 2003-03-07 Antibiotic compositions
CA 2478121 CA2478121A1 (en) 2002-03-07 2003-03-07 Antibiotic composition

Publications (2)

Publication Number Publication Date
WO2003075852A2 true WO2003075852A2 (en) 2003-09-18
WO2003075852A3 true true WO2003075852A3 (en) 2004-07-15

Family

ID=27808882

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/007118 WO2003075852A3 (en) 2000-02-24 2003-03-07 Antibiotic composition

Country Status (4)

Country Link
EP (1) EP1487414A4 (en)
JP (1) JP2005526059A (en)
CA (1) CA2478121A1 (en)
WO (1) WO2003075852A3 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8889187B2 (en) 2000-02-24 2014-11-18 Shionogi Inc. Once a day amoxicillin product comprising immediate and delayed release dosage forms

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
WO2003086366A1 (en) * 2002-04-12 2003-10-23 F H Faulding & Co Limited An improved modified release preparation
US8715727B2 (en) * 2004-07-02 2014-05-06 Shionogi Inc. Tablet for pulsed delivery
US20080069870A1 (en) * 2005-04-12 2008-03-20 Elan Corporation Pic Controlled Release Compositions Comprising a Cephalosporin for the Treatment of a Bacterial Infection
EP1883396B1 (en) 2005-05-18 2013-07-03 DA Volterra Colonic delivery of adsorbents
US8048413B2 (en) 2006-05-17 2011-11-01 Helene Huguet Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules
US20090324736A1 (en) * 2008-05-07 2009-12-31 Salix Pharmaceuticals, Ltd. Methods of treating bowel diseases by administering a bowel cleanser and an antibiotic
US9119793B1 (en) 2011-06-28 2015-09-01 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for doxycycline

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4794001A (en) * 1986-03-04 1988-12-27 American Home Products Corporation Formulations providing three distinct releases
US5001692A (en) * 1987-04-21 1991-03-19 U.S. Philips Corporation Optical recording system providing a recording signal waveform adapted to the recording characteristics of the record carrier, and recording apparatus and record carrier for use in such systems

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6232166B2 (en) * 1983-06-15 1987-07-13 Shionogi & Co
JPS61210025A (en) * 1985-03-14 1986-09-18 Teisan Seiyaku Kk Stabilized antibioitc complex granule preparation
US4728512A (en) * 1985-05-06 1988-03-01 American Home Products Corporation Formulations providing three distinct releases
JPS63162619A (en) * 1986-12-25 1988-07-06 Teisan Seiyaku Kk Delayed soluble granule and sustained release complex granule using said granule
US5326570A (en) * 1991-07-23 1994-07-05 Pharmavene, Inc. Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine
US5260068A (en) * 1992-05-04 1993-11-09 Anda Sr Pharmaceuticals Inc. Multiparticulate pulsatile drug delivery system
US5260069A (en) * 1992-11-27 1993-11-09 Anda Sr Pharmaceuticals Inc. Pulsatile particles drug delivery system
EP0804174A4 (en) * 1993-07-21 1998-09-09 Univ Kentucky Res Found A multicompartment hard capsule with control release properties
DE19718012C1 (en) * 1997-04-29 1998-10-08 Jenapharm Gmbh A process for the preparation of perorally administered solid drug with controlled effective ingredient delivery
US5840329A (en) * 1997-05-15 1998-11-24 Bioadvances Llc Pulsatile drug delivery system
US6475518B1 (en) * 1998-06-30 2002-11-05 Karl William Baumgart Methods and compositions for treatment of disorders associated with chlamydia and similar bacterial infection
US6384081B2 (en) * 1998-10-09 2002-05-07 Charles L. Berman Treatment of diseases of the eye characterized by the formation of metalloproteinase
EP1267765A4 (en) * 2000-02-24 2008-12-24 Middlebrook Pharmaceuticals In Antibiotic and antifungal compositions
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6544555B2 (en) * 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4794001A (en) * 1986-03-04 1988-12-27 American Home Products Corporation Formulations providing three distinct releases
US5001692A (en) * 1987-04-21 1991-03-19 U.S. Philips Corporation Optical recording system providing a recording signal waveform adapted to the recording characteristics of the record carrier, and recording apparatus and record carrier for use in such systems

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1487414A4 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8889187B2 (en) 2000-02-24 2014-11-18 Shionogi Inc. Once a day amoxicillin product comprising immediate and delayed release dosage forms

Also Published As

Publication number Publication date Type
WO2003075852A2 (en) 2003-09-18 application
JP2005526059A (en) 2005-09-02 application
EP1487414A4 (en) 2007-12-12 application
CA2478121A1 (en) 2003-09-18 application
EP1487414A2 (en) 2004-12-22 application

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