WO2003068726A1 - Amide derivative of alicyclic amine and process for producing the same - Google Patents

Amide derivative of alicyclic amine and process for producing the same Download PDF

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Publication number
WO2003068726A1
WO2003068726A1 PCT/JP2002/013498 JP0213498W WO03068726A1 WO 2003068726 A1 WO2003068726 A1 WO 2003068726A1 JP 0213498 W JP0213498 W JP 0213498W WO 03068726 A1 WO03068726 A1 WO 03068726A1
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WO
WIPO (PCT)
Prior art keywords
same
producing
following formula
derivative
ring
Prior art date
Application number
PCT/JP2002/013498
Other languages
French (fr)
Japanese (ja)
Inventor
Atsuo Tatsumi
Jun Kuwana
Original Assignee
Daicel Chemical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daicel Chemical Industries, Ltd. filed Critical Daicel Chemical Industries, Ltd.
Priority to JP2003567861A priority Critical patent/JPWO2003068726A1/en
Publication of WO2003068726A1 publication Critical patent/WO2003068726A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines

Abstract

A process for producing an alicyclic-amine α-halocarboxamide derivative represented by the following formula (3): (3) (wherein ring Z represents an optionally substituted alicyclic hydrocarbon ring; m is an integer of 1 or larger; and R1, R2, and R3 are the same or different and each represents halogeno, hydrogen, or an optionally substituted hydrocarbon group, provided that at least one of R1, R2, and R3 is halogeno) which comprises reacting an amine compound represented by the following formula (1): (1) (wherein ring Z and m are the same as defined above) with either an α-halocarboxylic acid represented by the following formula (2): (2) (wherein R1, R2, and R3 are the same as defined above) or a reactive derivative thereof in the presence of a base. By this process, an α-halocarboxamide derivative utilizable as, e.g., a photographic chemical can be efficiently and economically produced.
PCT/JP2002/013498 2001-12-27 2002-12-25 Amide derivative of alicyclic amine and process for producing the same WO2003068726A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2003567861A JPWO2003068726A1 (en) 2001-12-27 2002-12-25 Amide derivatives of alicyclic amines and their production

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2001397963 2001-12-27
JP2001-397963 2001-12-27
JP2001-401872 2001-12-28
JP2001401872 2001-12-28

Publications (1)

Publication Number Publication Date
WO2003068726A1 true WO2003068726A1 (en) 2003-08-21

Family

ID=27736407

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/013498 WO2003068726A1 (en) 2001-12-27 2002-12-25 Amide derivative of alicyclic amine and process for producing the same

Country Status (2)

Country Link
JP (1) JPWO2003068726A1 (en)
WO (1) WO2003068726A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1925433A1 (en) 2006-11-22 2008-05-28 EOS GmbH Electro Optical Systems Coating apparatus for application of a layer of powdered build material in an apparatus for layered production of a three-dimensional object
WO2010011570A1 (en) * 2008-07-25 2010-01-28 H. Lundbeck A/S Adamantyl diamide derivatives and uses of same
CN103539690A (en) * 2013-10-12 2014-01-29 合肥久诺医药科技有限公司 Intermediate for synthesis of amantadine drugs and its preparation method and use

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994029310A1 (en) * 1993-06-10 1994-12-22 Smithkline Beecham Corporation Process for asymmetric total synthesis of camptothecin
JPH11239730A (en) * 1997-01-14 1999-09-07 Daicel Chem Ind Ltd Catalyst for nitration or calboxylation, method of nitration or carboxylation using same, and adamantane derivative
WO2001062706A1 (en) * 2000-02-22 2001-08-30 Panorama Research, Inc. Aminoadamantane derivatives as therapeutic agents
JP2003050441A (en) * 2001-05-29 2003-02-21 Konica Corp Thermally developable photographic sensitive material and image forming method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994029310A1 (en) * 1993-06-10 1994-12-22 Smithkline Beecham Corporation Process for asymmetric total synthesis of camptothecin
JPH11239730A (en) * 1997-01-14 1999-09-07 Daicel Chem Ind Ltd Catalyst for nitration or calboxylation, method of nitration or carboxylation using same, and adamantane derivative
WO2001062706A1 (en) * 2000-02-22 2001-08-30 Panorama Research, Inc. Aminoadamantane derivatives as therapeutic agents
JP2003050441A (en) * 2001-05-29 2003-02-21 Konica Corp Thermally developable photographic sensitive material and image forming method

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1925433A1 (en) 2006-11-22 2008-05-28 EOS GmbH Electro Optical Systems Coating apparatus for application of a layer of powdered build material in an apparatus for layered production of a three-dimensional object
WO2010011570A1 (en) * 2008-07-25 2010-01-28 H. Lundbeck A/S Adamantyl diamide derivatives and uses of same
US7947680B2 (en) 2008-07-25 2011-05-24 H. Lundbeck A/S Adamantyl diamide derivatives and uses of same
CN102105437A (en) * 2008-07-25 2011-06-22 H.隆德贝克有限公司 Adamantyl diamide derivatives and uses of same
JP2011529057A (en) * 2008-07-25 2011-12-01 ハー・ルンドベック・アクチエゼルスカベット Adamantyl diamide derivatives and their use
US8198275B2 (en) 2008-07-25 2012-06-12 H. Lundbeck A/S Adamantyl diamide derivatives and uses of same
US8389519B2 (en) 2008-07-25 2013-03-05 H. Lundbeck A/S Adamantyl diamide derivatives and uses of same
EA019546B1 (en) * 2008-07-25 2014-04-30 Х. Лундбекк А/С Adamantyl diamide derivatives, pharmaceutical composition containing same and uses thereof
US8716284B2 (en) 2008-07-25 2014-05-06 H. Lundbeck A/S Adamantyl diamide derivatives and uses of same
CN102105437B (en) * 2008-07-25 2014-07-23 H.隆德贝克有限公司 Adamantyl diamide derivatives and uses of same
CN103539690A (en) * 2013-10-12 2014-01-29 合肥久诺医药科技有限公司 Intermediate for synthesis of amantadine drugs and its preparation method and use

Also Published As

Publication number Publication date
JPWO2003068726A1 (en) 2005-06-02

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