WO2003020172A1 - An implantable and sealable system for unidirectional delivery of therapeutic agents to targeted tissues - Google Patents
An implantable and sealable system for unidirectional delivery of therapeutic agents to targeted tissues Download PDFInfo
- Publication number
- WO2003020172A1 WO2003020172A1 PCT/US2002/027434 US0227434W WO03020172A1 WO 2003020172 A1 WO2003020172 A1 WO 2003020172A1 US 0227434 W US0227434 W US 0227434W WO 03020172 A1 WO03020172 A1 WO 03020172A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tissue
- agent
- preferentially
- organ
- sealing
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
- A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
Abstract
Description
Claims
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2456025A CA2456025C (en) | 2001-08-29 | 2002-08-28 | An implantable and sealable system for unidirectional delivery of therapeutic agents to tissues |
AU2002324811A AU2002324811B2 (en) | 2001-08-29 | 2002-08-28 | An implantable and sealable system for unidirectional delivery of therapeutic agents to targeted tissues |
BR0205990-8A BR0205990A (en) | 2001-08-29 | 2002-08-28 | An implantable one-way delivery system for therapeutic tissue agents |
CN028215613A CN1578647B (en) | 2001-08-29 | 2002-08-28 | Implantable and sealable system for unidirectional delivery of therapeutic agents to tissues |
EP02759478A EP1420716B1 (en) | 2001-08-29 | 2002-08-28 | An implantable and sealable system for unidirectional delivery of therapeutic agents to targeted tissues |
JP2003524486A JP2005501602A (en) | 2001-08-29 | 2002-08-28 | Sealable implantable device for unidirectional delivery of therapeutic agents to tissue |
ES02759478T ES2393101T3 (en) | 2001-08-29 | 2002-08-28 | Implantable and sealable system for unidirectional administration of therapeutic agents to target tissues |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31595201P | 2001-08-29 | 2001-08-29 | |
US60/315,952 | 2001-08-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003020172A1 true WO2003020172A1 (en) | 2003-03-13 |
Family
ID=23226807
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/027434 WO2003020172A1 (en) | 2001-08-29 | 2002-08-28 | An implantable and sealable system for unidirectional delivery of therapeutic agents to targeted tissues |
Country Status (12)
Country | Link |
---|---|
US (1) | US7195774B2 (en) |
EP (1) | EP1420716B1 (en) |
JP (2) | JP2005501602A (en) |
CN (1) | CN1578647B (en) |
AU (1) | AU2002324811B2 (en) |
BR (1) | BR0205990A (en) |
CA (1) | CA2456025C (en) |
ES (1) | ES2393101T3 (en) |
PT (1) | PT1420716E (en) |
RU (1) | RU2311892C2 (en) |
WO (1) | WO2003020172A1 (en) |
ZA (1) | ZA200304159B (en) |
Cited By (21)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2004073551A2 (en) * | 2003-02-18 | 2004-09-02 | Massachusetts Eye And Ear Infirmary | Transscleral drug delivery device and related methods |
WO2005065601A3 (en) * | 2003-12-22 | 2005-09-09 | Bausch & Lomb | Drug delivery device |
EP1658109A2 (en) * | 2003-08-26 | 2006-05-24 | Vista Scientific LLC | Ocular drug delivery device |
JP2008504938A (en) * | 2004-07-02 | 2008-02-21 | レイザー,エリオット | Treatment medium delivery apparatus and method for delivering treatment medium to eyes using the delivery apparatus |
EP1946723A1 (en) * | 2005-10-31 | 2008-07-23 | Life Spring Biotech Co., Ltd. | Scleral buckle band and method for making it |
US7621907B2 (en) | 2002-03-11 | 2009-11-24 | Alcon, Inc. | Implantable drug delivery system |
US7749528B2 (en) | 2001-08-29 | 2010-07-06 | Ricardo Azevedo Pontes De Carvalho | Implantable and sealable medical device for unidirectional delivery of therapeutic agents to tissues |
US7943162B2 (en) | 1999-10-21 | 2011-05-17 | Alcon, Inc. | Drug delivery device |
WO2013111121A1 (en) * | 2012-01-27 | 2013-08-01 | Ecole Polytechnique Federale De Lausanne (Epfl) | Device for the transplantation of cells in suspension |
US8722097B2 (en) | 2004-04-30 | 2014-05-13 | Allergan, Inc. | Oil-in-water method for making polymeric implants containing a hypotensive lipid |
US8900622B1 (en) | 2004-04-30 | 2014-12-02 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
US9102105B2 (en) | 2011-09-13 | 2015-08-11 | Vista Scientific Llc | Method for forming an ocular drug delivery device |
US9326949B2 (en) | 2004-04-30 | 2016-05-03 | Allergan, Inc. | Method of making oil-in-oil emulsified polymeric implants containing a hypotensive lipid |
US9775846B2 (en) | 2004-04-30 | 2017-10-03 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related implants |
US10010502B2 (en) | 2015-05-19 | 2018-07-03 | Amorphex Therapeutics Llc | Device that delivers a sustained low-dose of a myopia-suppressing drug, while preserving pupillary function and accommodation |
US10406029B2 (en) | 2001-04-07 | 2019-09-10 | Glaukos Corporation | Ocular system with anchoring implant and therapeutic agent |
US10959941B2 (en) | 2014-05-29 | 2021-03-30 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
US11253394B2 (en) | 2013-03-15 | 2022-02-22 | Dose Medical Corporation | Controlled drug delivery ocular implants and methods of using same |
US11318043B2 (en) | 2016-04-20 | 2022-05-03 | Dose Medical Corporation | Bioresorbable ocular drug delivery device |
US11564833B2 (en) | 2015-09-25 | 2023-01-31 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
US11925578B2 (en) | 2015-09-02 | 2024-03-12 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
Families Citing this family (154)
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CA2358296A1 (en) * | 1999-01-05 | 2000-07-13 | Anthony P. Adamis | Targeted transscleral controlled release drug delivery to the retina and choroid |
FR2822049B1 (en) * | 2001-03-13 | 2003-08-01 | Dbv Medica 1 | PATCH INTENDED IN PARTICULAR TO DETECT THE STATE OF SENSITIZATION OF A SUBJECT TO AN ALLERGEN, METHOD OF MANUFACTURING AND USE |
US7635488B2 (en) * | 2001-03-13 | 2009-12-22 | Dbv Technologies | Patches and uses thereof |
EP1404297B1 (en) | 2001-06-12 | 2011-04-27 | The Johns Hopkins University School Of Medicine | Reservoir device for intraocular drug delivery |
RU2311892C2 (en) | 2001-08-29 | 2007-12-10 | КАРВАЛХО Рикардо А. П. ДЕ | Implantable sealable system for one-way delivery of therapeutic preparations to tissues |
AU2003217531A1 (en) * | 2002-05-02 | 2003-11-17 | Massachusetts Eye And Ear Infirmary | Ocular drug delivery systems and use thereof |
US20050143363A1 (en) * | 2002-09-29 | 2005-06-30 | Innorx, Inc. | Method for subretinal administration of therapeutics including steroids; method for localizing pharmacodynamic action at the choroid of the retina; and related methods for treatment and/or prevention of retinal diseases |
US20040225250A1 (en) * | 2003-05-05 | 2004-11-11 | Michael Yablonski | Internal shunt and method for treating glaucoma |
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US7850660B2 (en) * | 2003-12-19 | 2010-12-14 | Ethicon Endo-Surgery, Inc. | Implantable medical device with simultaneous attachment mechanism and method |
US7927599B2 (en) * | 2003-09-08 | 2011-04-19 | Ethicon, Inc. | Chondrocyte therapeutic delivery system |
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Also Published As
Publication number | Publication date |
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RU2004109574A (en) | 2005-04-10 |
EP1420716A1 (en) | 2004-05-26 |
CN1578647A (en) | 2005-02-09 |
JP2005501602A (en) | 2005-01-20 |
US20030064088A1 (en) | 2003-04-03 |
JP4374077B2 (en) | 2009-12-02 |
CA2456025C (en) | 2011-11-22 |
US7195774B2 (en) | 2007-03-27 |
CA2456025A1 (en) | 2003-03-13 |
JP2009254864A (en) | 2009-11-05 |
ZA200304159B (en) | 2004-08-30 |
EP1420716A4 (en) | 2010-10-27 |
RU2311892C2 (en) | 2007-12-10 |
EP1420716B1 (en) | 2012-08-15 |
CN1578647B (en) | 2010-04-07 |
PT1420716E (en) | 2012-11-21 |
BR0205990A (en) | 2004-01-13 |
AU2002324811B2 (en) | 2008-07-24 |
ES2393101T3 (en) | 2012-12-18 |
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