Connect public, paid and private patent data with Google Patents Public Datasets

Wicking methods and structures for use in sampling bodily fluids

Info

Publication number
WO2003020134B1
WO2003020134B1 PCT/US2002/027465 US0227465W WO2003020134B1 WO 2003020134 B1 WO2003020134 B1 WO 2003020134B1 US 0227465 W US0227465 W US 0227465W WO 2003020134 B1 WO2003020134 B1 WO 2003020134B1
Authority
WO
Grant status
Application
Patent type
Prior art keywords
sampling
member
device
incision
fluid
Prior art date
Application number
PCT/US2002/027465
Other languages
French (fr)
Other versions
WO2003020134A3 (en )
WO2003020134A2 (en )
Inventor
Edward P Perez
Original Assignee
Amira Medical
Edward P Perez
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/150022Source of blood for capillary blood or interstitial fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150053Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061Means for enhancing collection
    • A61B5/150068Means for enhancing collection by tissue compression, e.g. with specially designed surface of device contacting the skin area to be pierced
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150213Venting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150358Strips for collecting blood, e.g. absorbent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150412Pointed piercing elements, e.g. needles, lancets for piercing the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150503Single-ended needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101Details
    • A61B5/15103Piercing procedure
    • A61B5/15105Purely manual piercing, i.e. the user pierces the skin without the assistance of any driving means or driving devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101Details
    • A61B5/15103Piercing procedure
    • A61B5/15107Piercing being assisted by a triggering mechanism
    • A61B5/15113Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101Details
    • A61B5/15115Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15117Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101Details
    • A61B5/15126Means for controlling the lancing movement, e.g. 2D- or 3D-shaped elements, tooth-shaped elements or sliding guides
    • A61B5/15128Means for controlling the lancing movement, e.g. 2D- or 3D-shaped elements, tooth-shaped elements or sliding guides comprising 2D- or 3D-shaped elements, e.g. cams, curved guide rails or threads
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15186Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
    • A61B5/15188Constructional features of reusable driving devices
    • A61B5/1519Constructional features of reusable driving devices comprising driving means, e.g. a spring, for propelling the piercing unit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15186Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
    • A61B5/15188Constructional features of reusable driving devices
    • A61B5/15192Constructional features of reusable driving devices comprising driving means, e.g. a spring, for retracting the lancet unit into the driving device housing
    • A61B5/15194Constructional features of reusable driving devices comprising driving means, e.g. a spring, for retracting the lancet unit into the driving device housing fully automatically retracted, i.e. the retraction does not require a deliberate action by the user, e.g. by terminating the contact with the patient's skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Abstract

A sampling member defines a passageway including an inlet opening for reception of a bodily fluid therein, and a wicking member having a first portion coupled with the sampling member adjacent to the inlet opening. The wicking member further includes a second portion displaced from the first portion for initially contacting the bodily fluid. In use the sampling member is placed adjacent to an incision site with the second portion of the wicking member positioned to have the bodily fluid first contact the wicking member and thereby draw the fluid from the incision site to the inlet opening. In related embodiments there is provided a sampling system and method which further includes a lancing device to create the incision and optionally expression members to urge the bodily fluid from the incision, preferably in an integrated unit.

Claims

AMENDED CLAIMS
[received by the International Bureau on 09 June 2003 (09.06.03); claims 1 and 2 amended, new claims 3-34 added (6 pages)]
L A sampling device for bodily fluids comprising: a sampling member defining a passageway including an inlet opening, the passageway configured for reception of the bodily fluid therein, said sampling member being positionable adjacent an incision site; and a wicking member having a first portion coupled with said sampling member at a location adjacent to the inlet opening, said wicking member further including a second portion displaced from the first portion, the second portion being closer to the incision site than the first portion when said sampling member is positioned adjacent to the incision site.
1. A method for collecting a bodily fluid from an incision site comprising: providing a sampling device including a sampling member defining a passageway including an inlet opening, the passageway configured for reception of the bodily fluid therein, the sampling device further including a wicking member having a first portion coupled with the sampling member at a location adjacent to the inlet opening, the wicking member further including a second portion displaced from the first portion; and positioning the sampling device adjacent to the incision site to have the second portion of the wicking member closer to the incision site than the first portion, whereby fluid at the incision site first contacts the wicking member and is thereby drawn from the incision site to the inlet opening of the sampling member.
3. The sampling device of claim 1, wherein: the sampling member has a top surface, a bottom surface and an aperture extending from the top surface to the bottom surface, the aperture being configured to surround the incision site; the inlet opening opens into the aperture; and the wicking member extends within the anerrnrfi
4. The sampling device of claim 3, further comprising a sealing member surrounding the aperture at the bottom surface of the sampling member to minimize fluid leakage.
5. The sampling device of claim 4, wherein the sealing member includes a hydrophobic surface to resist passage of the bodily fluid.
6. The sampling device of claim 4, further comprising a constricting system extending from the bottom surface to create a bulge of skin around the incision site.
7, The sampling device of claim 3, further comprising a constricting system provided around the aperture to create a bulge of skin around the incision site.
8. The sampling device of claim 7 , wherein the constricting system includes at least two deformable elements positioned on opposite sides of the aperture for engaging and constricting the skin.
9. The sampling device of claim 3, wherein the sampling member has a recessed surface between the inlet opening and the bottom surface to promote fluid flow into the inlet opening.
10. The sampling device of claim 1 , wherein the sampling member has a constricting system extending therefrom to create a bulge of skin around the incision site.
11. The sampling device of claim 1 , further comprising a test area in fluid communication with the passageway for testing the bodily fluid. 12, The sampling device of claim 11 , wherein the test area includes a test reagent covering absorbent material.
13. The sampling device of claim 1, wherein: the sampling member has a top surface, a bottom surface and an end edge; and the inlet opening communicates with the end edge at a location displaced from the bottom surface.
14. The sampling device of claim 13, wherein the sampling member has a recessed surface connecting between the inlet opening and the bottom surface.
15. The sampling device of claim 13, further comprising a sealing member located on the bottom surface to block passage of the bodily fluid.
16. The sampling device of claim 1 , further comprising: wherein the sampling member defines an aperture, the wicking member extending within the aperture; and a lancing device including a lancet for lancing skin, the lancing device defining a slot in which the sampling member is received, the aperture of the sampling member being positioned in alignment with the lancet in order for the lancet to lance the skin through the aperture,
17. The method of claim 2, further comprising lancing an incision into skin at the incision site with a lancet by extending the lancet through an aperture in the sampling member.
18, The method of claim 2, further comprising pressing a constricting system that extends from the sampling member to create a bulge of skin around the incision site.
1 . The method of claim 2, further comprising: drawing the fluid from the inlet opening, into the passageway and into a test area defined in the sampling member; and 5 testing the fluid in the test area.
20. A fluid sampling device, comprising: a test strip defining a passageway including an inlet opening, the test strip being positionable adjacent an incision, the passageway configured for reception of o bodily fluid from the incision; and means for wicking the fluid from the incision into the inlet opening positioned proximal the inlet opening.
21. The device of claim 20, wherein the means for wicking the fluid 5 includes a wicking member extending from the test strip adjacent the inlet opening.
22. The device of claim 20, wherein the means for wicking the fluid includes a lancet positioned adjacent the inlet opening and the incision, the lancet is provided with a hydrophilic outer surface to wick the fluid into the inlet opening. 0
23. A fluid sampling device, comprising: a sampling member defining a passageway including an inlet opening; a deformable expression member positioned proximal the inlet opening to form a bulge of skin upon pressing the expression member against the skin; and 5 a lancet configured to form an incision in the skin, the lancet extending proximal the inlet opening to draw fluid into the inlet opening.
24. The device of claim 23, wherein the lancet is slidably positioned inside the passageway. 0
25. The device of claim 24, wherein the sampling member includes a capillary tube.
26. The device of claim 24, further comprising a pressing member positioned inside the deformable expression member proximal the inlet opening to pull apart and maintain the incision open upon formation of the incision.
27. The device of claim 24, further comprising a test strip positioned within the passageway to test the fluid.
28. The device of claim 23, wherein the sampling member includes a capillary tube.
29. The device of claim 23, further comprising a pressing member positioned inside the deformable expression member proximal the inlet opening to pull apart and maintain the incision open upon formation of the incision.
30. The device of claim 23, further comprising a test strip positioned within the passageway to test the fluid.
31. The device of claim 23, wherein the expression member has a cylindrical shape.
32. A method of sampling bodily fluid from an incision, comprising: forming a bulge of skin by pressing a deformable expression member of a sampling device against the s in; lancing the bulge of the skin with a lancet of the sampling device to form the incision; and positioning the lancet proximal the incision to draw the fluid from the incision into an inlet opening of a passageway defined in a sampling member of the sampling device.
33. The method of claim 32, further comprising pressing a pressing member of the sampling device against the skin to spread apart the incision.
34. The method of claim 32, wherein: the sampling member includes a capillary tube; the lancet is longitudinally moveable inside the passageway in the capillary tube; and said lancing includes extending the lancet from the capillary tube.
PCT/US2002/027465 2001-08-29 2002-08-29 Wicking methods and structures for use in sampling bodily fluids WO2003020134B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US31587301 true 2001-08-29 2001-08-29
US60/315,873 2001-08-29

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20020759486 EP1423049A2 (en) 2001-08-29 2002-08-29 Wicking methods and structures for use in sampling bodily fluids
CA 2458208 CA2458208A1 (en) 2001-08-29 2002-08-29 Wicking methods and structures for use in sampling bodily fluids
JP2003524451A JP2005501591A (en) 2001-08-29 2002-08-29 Exudative methods and structures for use in sampling a body fluid

Publications (3)

Publication Number Publication Date
WO2003020134A2 true WO2003020134A2 (en) 2003-03-13
WO2003020134A3 true WO2003020134A3 (en) 2003-06-05
WO2003020134B1 true true WO2003020134B1 (en) 2003-08-07

Family

ID=23226424

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/027465 WO2003020134B1 (en) 2001-08-29 2002-08-29 Wicking methods and structures for use in sampling bodily fluids

Country Status (5)

Country Link
US (1) US7264627B2 (en)
JP (1) JP2005501591A (en)
CA (1) CA2458208A1 (en)
EP (1) EP1423049A2 (en)
WO (1) WO2003020134B1 (en)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
DE10057832C1 (en) * 2000-11-21 2002-02-21 Hartmann Paul Ag Blood analysis device has syringe mounted in casing, annular mounting carrying needles mounted behind test strip and being swiveled so that needle can be pushed through strip and aperture in casing to take blood sample
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
EP1399057B8 (en) 2001-06-08 2012-05-02 Roche Diagnostics GmbH Control solution packets and methods for calibrating body fluid sampling devices
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7699791B2 (en) 2001-06-12 2010-04-20 Pelikan Technologies, Inc. Method and apparatus for improving success rate of blood yield from a fingerstick
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7682318B2 (en) 2001-06-12 2010-03-23 Pelikan Technologies, Inc. Blood sampling apparatus and method
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7344507B2 (en) 2002-04-19 2008-03-18 Pelikan Technologies, Inc. Method and apparatus for lancet actuation
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7316700B2 (en) 2001-06-12 2008-01-08 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
WO2002100460A3 (en) 2001-06-12 2003-05-08 Don Alden Electric lancet actuator
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
EP1404235A4 (en) 2001-06-12 2008-08-20 Pelikan Technologies Inc Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7771368B2 (en) * 2002-07-01 2010-08-10 Terumo Kabushiki Kaisha Body fluid collecting device
WO2004060160A1 (en) 2002-12-24 2004-07-22 Roche Diagnostics Gmbh A sampling device utilizing biased capillary action
US7214200B2 (en) * 2002-12-30 2007-05-08 Roche Diagnostics Operations, Inc. Integrated analytical test element
EP1581114B1 (en) * 2002-12-30 2014-04-30 Roche Diagnostics GmbH Flexible test strip lancet device
EP1581115B1 (en) * 2002-12-30 2009-10-14 Roche Diagnostics GmbH Blood acquisition suspension system
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US7052652B2 (en) * 2003-03-24 2006-05-30 Rosedale Medical, Inc. Analyte concentration detection devices and methods
CN100350878C (en) * 2003-03-27 2007-11-28 泰尔茂株式会社 Humor sampling implement and method of humor sampling
EP1628567B1 (en) 2003-05-30 2010-08-04 Pelikan Technologies Inc. Method and apparatus for fluid injection
US20040248312A1 (en) * 2003-06-06 2004-12-09 Bayer Healthcare, Llc Sensor with integrated lancet
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
WO2005033659A3 (en) 2003-09-29 2007-01-18 Pelikan Technologies Inc Method and apparatus for an improved sample capture device
WO2005037095A1 (en) 2003-10-14 2005-04-28 Pelikan Technologies, Inc. Method and apparatus for a variable user interface
WO2005065414A3 (en) * 2003-12-31 2005-12-29 Pelikan Technologies Inc Method and apparatus for improving fluidic flow and sample capture
US7377903B2 (en) * 2004-03-05 2008-05-27 Roche Diagnostics Operations, Inc. Split tip expression device
US7322942B2 (en) * 2004-05-07 2008-01-29 Roche Diagnostics Operations, Inc. Integrated disposable for automatic or manual blood dosing
EP1751546A2 (en) 2004-05-20 2007-02-14 Albatros Technologies GmbH & Co. KG Printable hydrogel for biosensors
EP1765194A4 (en) 2004-06-03 2010-09-29 Pelikan Technologies Inc Method and apparatus for a fluid sampling device
US9775553B2 (en) * 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
DE102004033317A1 (en) 2004-07-09 2006-02-09 Roche Diagnostics Gmbh Analytical test element
US7645241B2 (en) * 2004-09-09 2010-01-12 Roche Diagnostics Operations, Inc. Device for sampling bodily fluids
US7604604B2 (en) * 2004-09-09 2009-10-20 Roche Diagnostics Operations, Inc. Device for sampling bodily fluids
US7488298B2 (en) * 2004-10-08 2009-02-10 Roche Diagnostics Operations, Inc. Integrated lancing test strip with capillary transfer sheet
US7775990B2 (en) * 2004-10-27 2010-08-17 Abbott Laboratories Blood expression device
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US9332938B2 (en) 2005-03-02 2016-05-10 Roche Diabetes Care, Inc. Flat lancet immobilization
US7695442B2 (en) * 2005-04-12 2010-04-13 Roche Diagnostics Operations, Inc. Integrated lancing test strip with retractable lancet
US8157749B2 (en) 2005-05-16 2012-04-17 Terumo Kabushiki Kaisha Blood component measurement device and tip for blood measurement
US20100081968A1 (en) * 2005-07-15 2010-04-01 Home Diagnostics, Inc. Test Strip With Integrated Lancet
FI121698B (en) * 2005-07-19 2011-03-15 Ihq Innovation Headquarters Oy Health Monitoring Device and sensor cartridge for the health monitoring device
JP2007050100A (en) * 2005-08-18 2007-03-01 Rohm Co Ltd Chip for sampling specimen
EP2989981A1 (en) 2005-09-30 2016-03-02 Intuity Medical, Inc. Multi-site body fluid sampling and analysis cartridge
CN101296656A (en) * 2005-11-29 2008-10-29 Ttm株式会社 Body fluid sampler and method therefor
CA2657086A1 (en) * 2006-07-06 2008-12-11 Rapidx Ltd Intergrated blood sampling and testing device and method of use thereof
JP4871083B2 (en) * 2006-09-27 2012-02-08 テルモ株式会社 The body fluid sampling unit
JP5043863B2 (en) * 2006-12-21 2012-10-10 パナソニック株式会社 The blood test apparatus
US8636672B2 (en) * 2007-02-28 2014-01-28 Nipro Diagnostics, Inc. Test strip with integrated lancet
WO2008154710A8 (en) * 2007-06-18 2010-02-25 União Brasileira De Educacão E Assistência - Sponsor Of Pucrs Blood collector device and blood analysis process
WO2009081405A3 (en) * 2007-12-25 2010-03-11 Rapidx Ltd. Devices and methods for reduced-pain blood sampling
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
EP2293719B1 (en) 2008-05-30 2015-09-09 Intuity Medical, Inc. Body fluid sampling device -- sampling site interface
JP5353223B2 (en) * 2008-12-17 2013-11-27 パナソニック株式会社 A sensor holder, a holder unit which blood sensor is attached to the sensor holder, a blood test apparatus to which the holder unit is attached
US8422740B2 (en) * 2009-01-15 2013-04-16 Scott Dylewski Methods for determining a liquid front position on a test strip
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
CN104434136A (en) 2009-03-02 2015-03-25 第七感生物系统有限公司 Devices for blood drawing
US8337422B2 (en) * 2009-07-14 2012-12-25 Becton, Dickinson And Company Diagnostic test strip having fluid transport features
WO2011094573A1 (en) 2010-01-28 2011-08-04 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
US20120238841A1 (en) * 2010-04-15 2012-09-20 Mark Castle Sample capture in one step for test strips
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
EP2384699B1 (en) * 2010-05-06 2012-12-12 Roche Diagnostics GmbH Lancet cartridge and method for its production
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
WO2011163347A3 (en) 2010-06-23 2012-03-29 Seventh Sense Biosystems, Inc. Sampling devices involving relatively little pain
JP2013538069A (en) 2010-07-16 2013-10-10 セブンス センス バイオシステムズ,インコーポレーテッド A low pressure environment for fluid transfer device
EP2992827B1 (en) 2010-11-09 2017-04-19 Seventh Sense Biosystems, Inc. Systems and interfaces for blood sampling
JP2014516644A (en) 2011-04-29 2014-07-17 セブンス センス バイオシステムズ,インコーポレーテッド Devices and methods for the collection and / or manipulation of blood spots or other body fluids
EP3106092A3 (en) * 2011-04-29 2017-03-08 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
ES2597081T3 (en) 2011-04-29 2017-01-13 Seventh Sense Biosystems, Inc. Delivery and / or receipt of fluids
US8641088B2 (en) 2011-05-10 2014-02-04 Tk Holdings Inc. Side-impact airbag module
WO2013020103A1 (en) 2011-08-03 2013-02-07 Intuity Medical, Inc. Devices and methods for body fluid sampling and analysis
US9788817B2 (en) * 2014-03-05 2017-10-17 Newvistas, Llc Urine specimen capture slit
US9480981B2 (en) 2014-07-25 2016-11-01 General Electric Company Sample collection and transfer device

Family Cites Families (135)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US254444A (en) * 1882-02-28 Chaeles w
US2714890A (en) 1953-08-06 1955-08-09 Vang Alfred Vibratory surgical instruments
US3086288A (en) * 1955-04-20 1963-04-23 Cavitron Ultrasonics Inc Ultrasonically vibrated cutting knives
US3208452A (en) 1960-09-08 1965-09-28 Panray Parlam Corp Surface treating device
NL6909366A (en) 1968-07-26 1970-01-29
US3741197A (en) * 1970-09-04 1973-06-26 Micromedia Syst Inc Percussion apparatus for blood sampling
US3673475A (en) * 1970-09-15 1972-06-27 Fred M Hufnagel Pulse drive circuit for coils of dental impact tools and the like
US3832776A (en) 1972-11-24 1974-09-03 H Sawyer Electronically powered knife
US4077406A (en) * 1976-06-24 1978-03-07 American Cyanamid Company Pellet implanter for animal treatment
US4154228A (en) * 1976-08-06 1979-05-15 California Institute Of Technology Apparatus and method of inserting a microelectrode in body tissue or the like using vibration means
DE2642896C3 (en) * 1976-09-24 1980-08-21 Sutor, Anton, Dr.Med.
GB1599654A (en) 1977-08-05 1981-10-07 Holman R R Automatic lancet
US4223674A (en) 1978-06-29 1980-09-23 Arthur J. McIntosh Implant gun
US4441373A (en) * 1979-02-21 1984-04-10 American Hospital Supply Corporation Collection tube for drawing samples of biological fluids
US4356826A (en) 1979-05-09 1982-11-02 Olympus Optical Co., Ltd. Stabbing apparatus for diagnosis of living body
US4360016A (en) 1980-07-01 1982-11-23 Transidyne General Corp. Blood collecting device
US4535769A (en) 1981-03-23 1985-08-20 Becton, Dickinson And Company Automatic retractable lancet assembly
US4503856A (en) * 1981-06-29 1985-03-12 Sherwood Medical Company Lancet injector
US4449529A (en) * 1981-11-18 1984-05-22 Becton Dickinson And Company Automatic retractable lancet assembly
US4535773A (en) 1982-03-26 1985-08-20 Inbae Yoon Safety puncturing instrument and method
US4462405A (en) 1982-09-27 1984-07-31 Ehrlich Joseph C Blood letting apparatus
US4517978A (en) * 1983-01-13 1985-05-21 Levin Paul D Blood sampling instrument
US4580564A (en) * 1983-06-07 1986-04-08 Andersen Michael A Finger pricking device
US4518384A (en) * 1983-06-17 1985-05-21 Survival Technology, Inc. Multiple medicament cartridge clip and medicament discharging device therefor
DE3340929A1 (en) * 1983-11-11 1985-05-23 Bayer Ag A process for the preparation of carbon monoxide
US4622974A (en) 1984-03-07 1986-11-18 University Of Tennessee Research Corporation Apparatus and method for in-vivo measurements of chemical concentrations
NL8401536A (en) * 1984-05-11 1985-12-02 Medscan B V I O Blood Sampler.
US4653511A (en) * 1984-10-05 1987-03-31 Goch Thomas A Microsample blood collecting device
US5279294A (en) * 1985-04-08 1994-01-18 Cascade Medical, Inc. Medical diagnostic system
US4787398A (en) 1985-04-08 1988-11-29 Garid, Inc. Glucose medical monitoring system
US4627445A (en) * 1985-04-08 1986-12-09 Garid, Inc. Glucose medical monitoring system
US4654513A (en) * 1985-07-31 1987-03-31 Hennessy Products, Inc. Newspaper vending machine
US4653513A (en) * 1985-08-09 1987-03-31 Dombrowski Mitchell P Blood sampler
US4750489A (en) * 1985-08-29 1988-06-14 Coopervision, Inc. Radial keratotomy knife and system using same
ES2003744A6 (en) * 1985-11-18 1988-11-16 Bajada Serge An apparatus for testing the sensory system in humans or animals
US4658821A (en) * 1986-01-08 1987-04-21 Packaging Corporation International A/K/A/ Medicore Ejector for an automatic lancet arm
US4685463A (en) 1986-04-03 1987-08-11 Williams R Bruce Device for continuous in vivo measurement of blood glucose concentrations
US4873993A (en) 1986-07-22 1989-10-17 Personal Diagnostics, Inc. Cuvette
US5029583A (en) 1986-07-22 1991-07-09 Personal Diagnostics, Inc. Optical analyzer
US4790979A (en) 1986-08-29 1988-12-13 Technimed Corporation Test strip and fixture
US4794926A (en) * 1986-11-24 1989-01-03 Invictus, Inc. Lancet cartridge
US5002054A (en) * 1987-02-25 1991-03-26 Ash Medical Systems, Inc. Interstitial filtration and collection device and method for long-term monitoring of physiological constituents of the body
GB8710470D0 (en) 1987-05-01 1987-06-03 Mumford Ltd Owen Blood sampling devices
US4805623A (en) * 1987-09-04 1989-02-21 Vander Corporation Spectrophotometric method for quantitatively determining the concentration of a dilute component in a light- or other radiation-scattering environment
US4850973A (en) 1987-10-16 1989-07-25 Pavel Jordon & Associates Plastic device for injection and obtaining blood samples
US5014718A (en) * 1988-01-22 1991-05-14 Safety Diagnostics, Inc. Blood collection and testing method
US5070886A (en) 1988-01-22 1991-12-10 Safety Diagnostice, Inc. Blood collection and testing means
US4883068A (en) 1988-03-14 1989-11-28 Dec In Tech, Inc. Blood sampling device and method
US5320808A (en) * 1988-08-02 1994-06-14 Abbott Laboratories Reaction cartridge and carousel for biological sample analyzer
US4924879A (en) * 1988-10-07 1990-05-15 Brien Walter J O Blood lancet device
US4995402A (en) 1988-10-12 1991-02-26 Thorne, Smith, Astill Technologies, Inc. Medical droplet whole blood and like monitoring
US4920977A (en) * 1988-10-25 1990-05-01 Becton, Dickinson And Company Blood collection assembly with lancet and microcollection tube
US4994073A (en) * 1989-02-22 1991-02-19 United States Surgical Corp. Skin fastener
US5035704A (en) 1989-03-07 1991-07-30 Lambert Robert D Blood sampling mechanism
US5054499A (en) * 1989-03-27 1991-10-08 Swierczek Remi D Disposable skin perforator and blood testing device
US5402798A (en) * 1991-07-18 1995-04-04 Swierczek; Remi Disposable skin perforator and blood testing device
US4953552A (en) 1989-04-21 1990-09-04 Demarzo Arthur P Blood glucose monitoring system
US5145565A (en) 1989-05-01 1992-09-08 Spacelabs, Inc. Contamination-free method and apparatus for measuring body fluid chemical parameters
US4976724A (en) 1989-08-25 1990-12-11 Lifescan, Inc. Lancet ejector mechanism
US5415169A (en) * 1989-11-21 1995-05-16 Fischer Imaging Corporation Motorized mammographic biopsy apparatus
US4994068A (en) * 1989-11-24 1991-02-19 Unidex, Inc. Combination sterile pad support and lancet containing lancet disposal element
US5097810A (en) * 1990-04-06 1992-03-24 Henry Fishman Allergy testing apparatus and method
US5066859A (en) 1990-05-18 1991-11-19 Karkar Maurice N Hematocrit and oxygen saturation blood analyzer
US5152775A (en) 1990-10-04 1992-10-06 Norbert Ruppert Automatic lancet device and method of using the same
US5188118A (en) * 1990-11-07 1993-02-23 Terwilliger Richard A Automatic biopsy instrument with independently actuated stylet and cannula
US5189751A (en) * 1991-03-21 1993-03-02 Gemtech, Inc. Vibrating toothbrush using a magnetic driver
US5163442A (en) 1991-07-30 1992-11-17 Harry Ono Finger tip blood collector
US5231993A (en) 1991-11-20 1993-08-03 Habley Medical Technology Corporation Blood sampler and component tester with guide member
US5222504A (en) * 1992-02-11 1993-06-29 Solomon Charles L Disposable neurological pinwheel
JP2572823Y2 (en) * 1992-02-13 1998-05-25 株式会社アドバンス Simple blood collection device
GB9207120D0 (en) * 1992-04-01 1992-05-13 Owen Mumford Ltd Improvements relating to blood sampling devices
DE4212315A1 (en) * 1992-04-13 1993-10-14 Boehringer Mannheim Gmbh Blood lancet device for withdrawing blood for diagnostic purposes
US5318583A (en) * 1992-05-05 1994-06-07 Ryder International Corporation Lancet actuator mechanism
US5217480A (en) * 1992-06-09 1993-06-08 Habley Medical Technology Corporation Capillary blood drawing device
US5277198A (en) * 1992-07-27 1994-01-11 Ryder International Corporation Blood sampling syringe
US5324302A (en) * 1992-10-13 1994-06-28 Sherwood Medical Company Lancet with locking cover
US5421816A (en) * 1992-10-14 1995-06-06 Endodermic Medical Technologies Company Ultrasonic transdermal drug delivery system
US5529074A (en) * 1993-02-26 1996-06-25 Greenfield; Jon B. Uniform pressure diagnostic pinwheel
US5395387A (en) * 1993-02-26 1995-03-07 Becton Dickinson And Company Lancet blade designed for reduced pain
US5353806A (en) 1993-03-04 1994-10-11 The Venture Fund Of Washington Liquid collection device
EP0622626B1 (en) * 1993-04-23 2002-03-06 Boehringer Mannheim Gmbh System for analysing the components of fluid samples
JP2630197B2 (en) 1993-04-28 1997-07-16 株式会社ニッショー Blood suction device
DE4320463A1 (en) 1993-06-21 1994-12-22 Boehringer Mannheim Gmbh Blood lancet device for withdrawing blood for diagnostic purposes
JP3494183B2 (en) 1993-08-10 2004-02-03 株式会社アドバンス Simple blood collection device
US5582184A (en) * 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
WO1995010977A1 (en) * 1993-10-20 1995-04-27 Varro, Anne, Marie Lancet device with irretrievably retractable piercing member
US5472427A (en) 1993-10-22 1995-12-05 Rammler; David H. Trocar device
US5885211A (en) * 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
US5458140A (en) 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
US5445611A (en) 1993-12-08 1995-08-29 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal delivery with ultrasound and chemical enhancers
US5474084A (en) 1994-03-15 1995-12-12 Cunniff; Joseph G. Algesimeter with detachable pin wheel
US5591139A (en) * 1994-06-06 1997-01-07 The Regents Of The University Of California IC-processed microneedles
US5569212A (en) 1994-07-22 1996-10-29 Raya Systems, Inc. Apparatus for electrically determining injection doses in syringes
US5514152A (en) * 1994-08-16 1996-05-07 Specialized Health Products, Inc. Multiple segment encapsulated medical lancing device
US5630986A (en) * 1995-01-13 1997-05-20 Bayer Corporation Dispensing instrument for fluid monitoring sensors
US5575403A (en) * 1995-01-13 1996-11-19 Bayer Corporation Dispensing instrument for fluid monitoring sensors
US5628764A (en) * 1995-03-21 1997-05-13 Schraga; Steven Collar lancet device
CA2170560C (en) * 1995-04-17 2005-10-25 Joseph L. Moulton Means of handling multiple sensors in a glucose monitoring instrument system
JPH08317917A (en) * 1995-05-25 1996-12-03 Advance Co Ltd Blood drawing device
KR0135178Y1 (en) * 1995-06-26 1999-03-20 김인환 Lancet device for obtaining blood samples
US5730753A (en) * 1995-07-28 1998-03-24 Apls Co., Ltd. Assembly for adjusting pricking depth of lancet
US5709699A (en) * 1995-09-01 1998-01-20 Biosafe Diagnostics Corporation Blood collection and testing device
US5879367A (en) * 1995-09-08 1999-03-09 Integ, Inc. Enhanced interstitial fluid collection
US5628309A (en) * 1996-01-25 1997-05-13 Raya Systems, Inc. Meter for electrically measuring and recording injection syringe doses
DE19604156A1 (en) * 1996-02-06 1997-08-07 Boehringer Mannheim Gmbh Cutting device for skin for painless removal of small quantities of blood
US5916229A (en) * 1996-02-07 1999-06-29 Evans; Donald Rotating needle biopsy device and method
EP1579814A3 (en) * 1996-05-17 2006-06-14 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
US5879311A (en) * 1996-05-17 1999-03-09 Mercury Diagnostics, Inc. Body fluid sampling device and methods of use
ES2121565T6 (en) * 1996-05-17 1998-11-16 Mercury Diagnostics Inc A disposable device for use in a sampling of body fluids.
US5758643A (en) * 1996-07-29 1998-06-02 Via Medical Corporation Method and apparatus for monitoring blood chemistry
FI112029B (en) * 1996-09-02 2003-10-31 Nokia Corp The device, such as receiving and analyzing blood samples in liquid samples
US5714390A (en) * 1996-10-15 1998-02-03 Bio-Tech Imaging, Inc. Cartridge test system for the collection and testing of blood in a single step
ES2384705T3 (en) * 1996-10-30 2012-07-11 F. Hoffmann-La Roche Ag synchronized analyte test system
US6071251A (en) * 1996-12-06 2000-06-06 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
CA2575064C (en) * 1997-12-31 2010-02-02 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
JP3394262B2 (en) * 1997-02-06 2003-04-07 イー.ヘラー アンド カンパニー Small volume in vitro analyte sensor
US5951493A (en) * 1997-05-16 1999-09-14 Mercury Diagnostics, Inc. Methods and apparatus for expressing body fluid from an incision
US5964718A (en) * 1997-11-21 1999-10-12 Mercury Diagnostics, Inc. Body fluid sampling device
DE19824036A1 (en) * 1997-11-28 1999-06-02 Roche Diagnostics Gmbh Analytical instrument with lancing
US5871494A (en) * 1997-12-04 1999-02-16 Hewlett-Packard Company Reproducible lancing for sampling blood
US6036924A (en) * 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6193673B1 (en) * 1998-02-20 2001-02-27 United States Surgical Corporation Biopsy instrument driver apparatus
US6391005B1 (en) * 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6139562A (en) * 1998-03-30 2000-10-31 Agilent Technologies, Inc. Apparatus and method for incising
US6210420B1 (en) * 1999-01-19 2001-04-03 Agilent Technologies, Inc. Apparatus and method for efficient blood sampling with lancet
US6132449A (en) * 1999-03-08 2000-10-17 Agilent Technologies, Inc. Extraction and transportation of blood for analysis
US6231531B1 (en) * 1999-04-09 2001-05-15 Agilent Technologies, Inc. Apparatus and method for minimizing pain perception
DE19945828B4 (en) * 1999-09-24 2011-06-01 Roche Diagnostics Gmbh Analytical element and method for determining an analyte in liquid
JP4210782B2 (en) * 1999-10-13 2009-01-21 アークレイ株式会社 Blood collection position display device
US6228100B1 (en) * 1999-10-25 2001-05-08 Steven Schraga Multi-use lancet device
US6364889B1 (en) * 1999-11-17 2002-04-02 Bayer Corporation Electronic lancing device
US6379969B1 (en) * 2000-03-02 2002-04-30 Agilent Technologies, Inc. Optical sensor for sensing multiple analytes
US6375627B1 (en) * 2000-03-02 2002-04-23 Agilent Technologies, Inc. Physiological fluid extraction with rapid analysis
US6561989B2 (en) * 2000-07-10 2003-05-13 Bayer Healthcare, Llc Thin lance and test sensor having same
EP1203563A3 (en) * 2000-10-31 2004-01-02 Boehringer Mannheim Gmbh Analyzing mean with integrated lancet

Also Published As

Publication number Publication date Type
US20030060730A1 (en) 2003-03-27 application
US7264627B2 (en) 2007-09-04 grant
JP2005501591A (en) 2005-01-20 application
WO2003020134A3 (en) 2003-06-05 application
CA2458208A1 (en) 2003-03-13 application
WO2003020134A2 (en) 2003-03-13 application
EP1423049A2 (en) 2004-06-02 application

Similar Documents

Publication Publication Date Title
WO2001097895A3 (en) A catheter system
WO2004019765A3 (en) Methods and devices for maintaining a space-occupying device within a stomach
WO2007138674A1 (en) Endoscope treatment system
WO2006058079A3 (en) Expandable device for providing access to the spine
WO2003096883A3 (en) Combined diagnostic and therapeutic ultrasound system
WO2002101359A3 (en) Integrated blood sampling analysis system with multi-use sampling module
WO2005084546A3 (en) Body fluid sampling device
WO2001021058A3 (en) Device and method for determining a depth of an incision
WO2001073395A3 (en) Method of preventing short sampling of a capillary or wicking fill device
WO2010013808A1 (en) Method for assaying in vivo component, data processing method for assaying in vivo component and apparatus and collection member for assaying in vivo component
WO2004045375A3 (en) Cap for a dermal tissue lancing device
WO2007041642A3 (en) Externally-applied patient interface system and method
WO2002100254A3 (en) Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
WO2007084367A3 (en) Tissue penetration device
WO2004060174A3 (en) Method and apparatus for loading penetrating members
WO2005001418A3 (en) Method and apparatus for body fluid sampling and analyte sensing
WO2006054107A3 (en) Method and apparatus for treatment of cardiac valves
WO2006072004A3 (en) Method and apparatus for analyte measurement test time
USD606664S1 (en) Assay device and housing combined
WO2002036021A3 (en) Systems, devices and methods for suturing patient tissue
WO2007054335A3 (en) Pricking element, pricking system, and skin detection method
WO2006053309A3 (en) Improved energy delivery devices and methods
WO2006093975A2 (en) Tissue manipulation and securement system
WO2005034721A8 (en) Lancing device end cap with blood-directing contact face
WO2007089897A3 (en) Inflatable-deflatable passive exercise unit

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS JP KE KG KP KR LC LK LR LS LT LU LV MA MD MG MN MW MX MZ NO NZ OM PH PL PT RU SD SE SG SI SK SL TJ TM TN TR TZ UA UG US UZ VC VN YU ZA ZM

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
B Later publication of amended claims

Free format text: 20030609

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2002759486

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2458208

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2003524451

Country of ref document: JP

WWP Wipo information: published in national office

Ref document number: 2002759486

Country of ref document: EP