Connect public, paid and private patent data with Google Patents Public Datasets

Rotating stent delivery system for side branch access and protection and method of using same.

Info

Publication number
WO2003017872A1
WO2003017872A1 PCT/US2002/026736 US0226736W WO2003017872A1 WO 2003017872 A1 WO2003017872 A1 WO 2003017872A1 US 0226736 W US0226736 W US 0226736W WO 2003017872 A1 WO2003017872 A1 WO 2003017872A1
Authority
WO
Grant status
Application
Patent type
Prior art keywords
member
stent
balloon
proximal
side
Prior art date
Application number
PCT/US2002/026736
Other languages
French (fr)
Other versions
WO2003017872A9 (en )
Inventor
Darrell C. Gumm
Original Assignee
Scimed Life Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/856Single tubular stent with a side portal passage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/954Instruments specially adapted for placement or removal of stents or stent-grafts for placing stents or stent-grafts in a bifurcation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/958Inflatable balloons for placing stents or stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2002/821Ostial stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1045Balloon catheters with special features or adapted for special applications for treating bifurcations, e.g. balloons in y-configuration, separate balloons or special features of the catheter for treating bifurcations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1056Balloon catheters with special features or adapted for special applications having guide wire lumens outside the main shaft, i.e. the guide wire lumen is within or on the surface of the balloon

Abstract

A catheter assembly and method of use comprises advancing a catheter having a rotatably mounted balloon (28,28') relative to the primary guide wire (12,12') to a vessel bifurcation along first and second guide wires (62).

Description

TITLE

Rotating Stent Delivery System for Side Branch Access and Protection and Method of Using Same

CROSS-REFERENCE TO RELATED APPLICATIONS

This application claims priority from US provisional application 60/314,467, Filed August 23, 2001 the entire contents of which are incorporated herein by reference.

STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH Not Applicable

BACKGROUND OF THE INVENTION Field of the Invention

At least one embodiment of the present invention is directed to the field of stents and stent delivery systems used to treat stenoses, and more particularly to stenoses at a bifurcation of a passage.

Description of the Related Art

Stent systems are widely used in the treatment of stenoses. Intravascular stents are used in coronary, renal, and carotid arteries, for example, to maintain an open passage through the artery. In patients whose coronary heart disease consists of focal lesions, stents have proven effective. For example, where only a single coronary artery is clogged or where there are short blockages in more than a single artery, stents have been used with a great amount of success. An intravascular stent may be positioned in a clogged artery by a catheter and is often set in place by inflating a balloon upon which the stent is mounted. This expands the diameter of the stent and opens the previously clogged artery. The balloon is then deflated and removed from the patient while the stent retains an open passage through the artery.

It is recognized, however, that a stent can be deployed in manners other than inflating and deflating a balloon. For example, self-expanding stents have been developed in which a cover is removed from over a stent, thereby allowing the stent to deploy or spring into place. It is also contemplated that other deployment mechanisms or means may be used or developed to advantageously deliver and deploy a stent in position. Nevertheless, a need still exists for properly delivering and locating a stent at a bifurcation. Although efforts have been made to use a stent at bifurcations, these sites have previously been inadequately treated by a stent. For example, U.S. Patent No. 5,749,825 is representative of a catheter system that treats stenoses at an arterial bifurcation. The disclosure of 5,749,825 is hereby incorporated by reference. A stent having different diameters has been proposed to allow placement in both a main passage, such as an artery, and a side branch passage, such as a continuation branch artery. Additionally, these stents generally have a circular opening which allows for unimpeded blood flow into the side branch artery. However, problems are still encountered in orienting the stent relative to the side branch at the bifurcation of the main and branch passages.

Many current devices rely on either passive torque (e.g., pushing the stent forward and allowing the stent that is fixed on the guide wire/balloon to passively rotate itself into place) or creating torque from outside of the patient to properly orient the stent delivery system in the passage. These devices and methods of achieving proper angular orientation have not been shown to be effective in properly placing and positioning the stent. As will be appreciated and understood by those skilled in the art, improper placement of the stent with respect to its rotational or circumferential orientation, or its longitudinal placement, could lead to obstruction of the side branch passage. It is important to properly position or center an opening formed in the bifurcated stent with the side branch passage to maximize flow therethrough.

Thus, a need exists for effectively treating stenosed passage bifurcations. This need includes more precise and exact longitudinal placement and rotational/ circumferential orientation of the stent.

Commercially available devices do not maintain side branch access at the time of stent deployment. This results in the potential for plaque shift and occlusion of the side branch passage.

It would also be advantageous if stents could be placed across the side branch while wire position is maintained thereby helping to protect and secure further access to the side branch. All US patents and applications and all other published documents mentioned anywhere in this application are incorporated herein by reference in their entirety.

Without limiting the scope of the invention a brief summary of some of the claimed embodiments of the invention is set forth below. Additional details of the summarized embodiments of the invention and/or additional embodiments of the invention may be found in the Detailed Description of the invention below.

A brief abstract of the technical disclosure in the specification is provided as well only for the purposes of complying with 37 C.F.R. 1.72. The abstract is not intended to be used for interpreting the scope of the claims.

BRIEF SUMMARY OF THE INVENTION

Some embodiments of the present invention include a freely rotating deployment system for a stent assembly maintaining side branch access and protection.

The present invention contemplates a new and improved apparatus and method that improves the orientation of a stent by providing a more exact placement of the stent relative to the side branch passage. This, in turn, leads to better protection of the side branch passage. The present invention has the potential for improvement in trackability of the stent delivery system.

At least one embodiment of the invention includes a freely rotatable catheter balloon surrounding a main hollow member or hypotube. The stent surrounds both the catheter balloon and the main hypotube. A side branch hollow member or side branch hypotube is attached to the catheter balloon and lies underneath the stent. A distal end of the side branch hypotube exits the stent at a desired longitudinal position while a proximal end of the side branch hypotube extends beyond the proximal end of the stent. At the distal exit point, the stent includes an opening that, after deployment of the stent, allows for blood flow through the ostium of the side branch artery.

The balloon is connected to the stent delivery system. In some embodiments, the balloon is attached both distally and proximally to rotate freely about the main hypotube. The rotating members rotate about the main hypotube and are limited longitudinally by first and second fixed members non-rotatably secured to the main hypotube. The balloon stent assembly rotates freely about the axis defined by the main hypotube and any radial movement is limited by the main hypotube. This construction allows the side branch guide wire to direct the stent assembly to rotate freely and passively to the proper circumferential orientation. Upon inflating the balloon, the fixed and rotated members secure the circumferential orientation of the stent delivery system. Thus, the side branch guide wire properly orients the stent delivery system in its correct position relative to the side branch.

A primary feature of some embodiments is that at the time of positioning the stent, the stent will be properly oriented relative to the side branch, i.e., a stent delivery system and method that correctly positions the stent in a bifurcated passage.

Another advantageous feature is side branch protection with the guide wire during stent deployment.

Another benefit of this invention resides in proper alignment of the stent delivery system in a bifurcated passage to achieve correct circumferential orientation relative to a side branch passage, and securing the desired orientation.

Yet another benefit of this invention is the ability to properly place the stent delivery system longitudinally relative to the side branch.

A further advantage of the system is that tangled wires pose less of a problem. These and other embodiments which characterize the invention are pointed out with particularity in the claims annexed hereto and forming a part hereof. However, for a better understanding of the invention, its advantages and objectives obtained by its use, reference should be made to the drawings which form a further part hereof and the accompanying descriptive matter, in which there is illustrated and described a embodiments of the invention. BRIEF DESCRIPTION OF THE SEVERAL VIEWS OF THE DRAWING(S)

A detailed description of the invention is hereafter described with specific reference being made to the drawings.

FIG. 1 is a cross-sectional side view of a rotating stent delivery catheter assembly for stenting an arterial bifurcation in its pre-deployment configuration, with the catheter balloon shown inflated.

FIG. 2 is a perspective view of the stent delivery assembly of FIG. 1 shown with a stent disposed about the balloon.

FIG. 3 is a perspective view of the stent delivery catheter assembly of FIG. 1 as it would appear in the collapsed state prior to having a stent mounted on the balloon.

FIG. 4 is a perspective view of a stent delivery system with the balloon in an inflated state and the side branch hypotube in an open condition. FIG. 5 is an enlarged view of the distal exit point of the side branch hypotube and the opening of the rotating stent delivery catheter assembly of FIG.2.

FIG. 6 is a perspective view of a proximal shaft of an alternate stent delivery catheter assembly having only one rotating joint that is self sealing when pressure is applied or withdrawn. FIG. 7 is an enlarged side view of a distal end of the rotating balloon assembly associated with FIG. 6.

FIG. 8 is an enlarged side view of the combined components of FIG. 6 and 7, specifically portions of the distal end of the proximal fixed shaft in FIG. 6 combined with the proximal end of the freely rotatable distal portion in FIG. 7 creating a rotating stent delivery catheter assembly with a single rotating j oint that is self sealing.

FIG. 9 is an enlarged side elevational view of FIG. 6 and 7 showing the combined of components of FIGS. 6-8 in their entirety.

DETAILED DESCRIPTION OF THE INVENTION While this invention may be embodied in many different forms, there are described in detail herein specific preferred embodiments of the invention. This description is an exemplification of the principles of the invention and is not intended to limit the invention to the particular embodiments illustrated. For the purposes of this disclosure, like reference numerals in the figures shall refer to like features unless otherwise indicated.

Referring now to the drawings wherein the showings are for the purposes of illustrating the preferred embodiments of the invention only and not for purposes of limiting same, FIG. 1 shows a stent delivery system or assembly 10. Assembly 10 includes a first guide member, or main guide wire 12 that extends axially through a first hollow or tubular member 14. The first hollow member 14 will also be identified as a main hypotube, although it will be appreciated that the particular shape or configuration of this component may change from that illustrated in the drawings. The main guide wire 12 is used as the delivery guide of the stent catheter assembly 10 to a stenosed region of a passage such as an artery (not shown). The main hypotube 14 is preferably a hollow cylinder with openings on both its distal and proximal ends, respectively end 16 and end 18, which allows for passage of the main guide wire 12 therethrough. A first fixed member, or distal fixed body 20 and a second fixed member, or proximal fixed body 22 are non-rotatably secured to distal end 16 and proximal end 18 of the main hypotube 14. Although described as separate elements, it will be understood that the fixed bodies 20 and 22 and the main hypotube 14 can be separate components that are secured together or an integrally formed assembly if desired for ease of manufacture or assembly. The fixed bodies 20 and 22 are preferably tapered from smaller diameter, axially outer ends to larger diameter, intermediate ends for reasons that will become more apparent below.

A first rotating member or distal rotating member 24 and a second rotating member or proximal rotating member 26 are axially spaced apart and located between the distal fixed body 20 and proximal fixed body 22. The rotating members 24 and 26 are preferably of the same general diameter throughout their length and rotate freely about the axis of the main hypotube 14.

Sealed to the proximal and distal rotating members 24 and 26 are opposite ends of a catheter balloon 28. A distal end 30 of the catheter balloon is sealinglyjoined to (or integrally formed with ) the distal rotating member 24 while a proximal end 32 of the catheter balloon is sealinglyjoined to (or integrally formed with) the proximal rotating member 26. Thus, the balloon is free to rotate relative to the main hypotube, a feature that provides advantages and benefits over known stent assemblies. It is also contemplated that the rotating members 24 and 26 can be formed of sealing or elastomeric material (or incorporate a separate seal member) so that slight axial movement of the balloon 28 and of the rotating members 24 and 26 engages and seals against the fixed bodies 20 and 22 upon inflation of the balloon 28. The balloon 28 and the rotating members 24 and 26 can hold high pressure and seal at the ends. It will be appreciated that the rotating members 24 and 26 are preferably constructed to maintain a cylindrical configuration under pressure so that the balloon 28 is free to rotate relative to the main hypotube 14 when pressurized.

In some embodiments the stent delivery catheter system further includes an outer hollow/tubular member or outer hypotube 40 received over the main hypotube 14. The outer hypotube 40 is radially spaced from the main hypotube 14 at a first or proximal end 42 to define an annular space 43 through which fluid from an external source (not shown) is introduced to inflate the balloon, hi at least one embodiment, a second or distal end 44 of the outer hypotube 40 is sealed to the main hypotube 14 so that fluid cannot escape therefrom. Alternatively, the distal end of the outer hypotube extends only partially into the balloon 28. In addition, one or more openings, or contrast ports, 46 are provided in the outer hypotube 40 at a location within the balloon 28 so that the fluid can enter the cavity defined between the balloon 28 and the outer hypotube 40 as illustrated by the directional arrows in FIG. 1. Alternatively, the opening 46 may define the distal end of the outer hypotube 40. h at least one embodiment, the balloon 28 is fully inflated at the proximal end 42 and then begins to inflate at the distal end 44. The outer hypotube 40 may be advantageously and integrally formed with the first and second fixed members 20 and 22 for ease of manufacture, although it will be appreciated that these may be separate members without departing from the scope and intent of the invention.

A conventional or specially designed medical device, such as a stent 50, encloses a portion of the catheter balloon 28, such as is shown in FIG.2. The stent 50 is typically a metal sleeve of mesh construction that is advanced into the stenosis riding on the balloon 28 of the catheter assembly 10. Once properly positioned, the balloon 28 is inflated with an inflation fluid, such as saline and contrast, through the passage 43 between the main hypotube 14 and the outer hypotube 40, which expands the balloon 28 and expands or radially opens the stent 50 to compress an atheroma that is narrowing the passage wall. Although the balloon 28 is subsequently deflated for removal from the patient with the catheter assembly 10, the stent 50 remains in its expanded state allowing increased flow through the previously closed/blocked (stenosed or narrowed) region. Alternatively, a self-expanding stent not requiring a balloon for delivery or deployment can be used without departing from the scope and intent of the present invention.

A second or branch tubular member 60, also referred to as a side branch hypotube, is provided between the catheter balloon 28 and the stent 50. As evident in FIG. 2, the side branch hypotube 60 carries or receives a side branch guide wire 62. The side branch hypotube 60 extends from the proximal end of the stent 50 between the stent and balloon and exits the stent at an intermediate longitudinal position through an opening 64. The opening 64 provides for both the exit of the side branch hypotube 60, as well as the unobstructed passage of blood flow into the side branch passage once the stent has been deployed. It should be understood, however, that the side branch hypotube opening 64 could be placed at any convenient position along the stent.

An enlarged view of the side branch hypotube opening 64 in the stent 50 is shown in FIG. 5. The side branch hypotube 60 exits from underneath the proximal end of the stent. Upon deployment of the stent 50, the side branch hypotube opening 64 allows for unobstructed blood flow to the ostium of the side branch passage. As will also be appreciated, the side branch hypotube 60 is fixed or secured to the exterior of the balloon. Thus, the side branch hypotube 60, balloon 28, and rotating members freely rotate as a unit relative to the main hypotube 14 for accurate, passive positioning with the side guide wire and thus accurate positioning of the stent 50 relative to a saddle point of the bifurcated passage. With continued reference to FIG. 2, the catheter balloon 28 is inflated, the stent 50 is deployed, and the rotating members 24 and 26 are interlocked with the fixed members 20 and 22 to stop the rotating action of the stent delivery system and create a pressure tight system.

The side branch hypotube 60 may also be slit 66 along its longitudinal length to facilitate removal of the side guide wire 62 as is shown in FIGs. 3 and 4. The side branch hypotube 60 is secured to the balloon 28 along its length at a circumferential location opposite the longitudinal slit, i.e., diametrically opposite the slit 66. The natural elasticity of the side branch hypotube 60 is utilized so that when the balloon 28 is inflated, such as is shown, the side branch hypotube 60 is substantially cylindrical in shape to enclose the portion of the side guide wire 62 therein such as is shown in FIG.2. When the balloon is inflated, it exerts a tensile force on the side branch hypotube 60 that opens the hypotube 60 along its length, such as in the manner shown in FIG. 4. As a result the side guide wire 62 is released through the slit 66. When the balloon 28 is deflated, such as is shown in FIG. 3, the side branch hypotube 60 again adopts a cylindrical conformation whereby the remainder of the stent delivery system (balloon and catheter) can be easily removed.

The split side branch hypotube 60 offers another desirable feature. The split hypotube 60 allows for immediate placement of a second balloon into the side branch for simultaneous "kissing" balloon inflation. In other words, first and second balloons are simultaneously located in the main and side branch passages such that their proximal ends abut and their distal ends are placed in each respective branch. This is to be contrasted with use of an unsplit or solid side branch hypotube which would require removal of the first balloon prior to insertion of a balloon in the side branch.

An alternative rotating stent delivery system is illustrated in FIGs. 6-9. For purposes of brevity, like components will be referenced by like numerals with a primed suffix (') and new elements will be identified by new numerals.

A proximal shaft is generally well known in the art and may take numerous forms; however, the proximal shaft 70 shown in FIGs. 6-9 preferably includes a bushing 72 at a distal end and a seal 74 comprised of a soft material. The seal 74 is connected to the proximal shaft 70 and, as shown, tapers to a smaller diameter and envelops the main hypotube 14', as is shown in FIGs. 8 and 9. Within lumen 76 of the proximal shaft 70, the bushing 72 abuts against an interior distal end of the proximal shaft.

With reference now to FIG.7, a distal rotating portion of proximal shaft 70 is shown. A separate hypotube 14' includes a proximal end with a first bushing 80 and a second bushing 82 axially spaced therefrom along the separate hypotube 14'. A second seal 84 comprised of a soft material, is connected to the first bushing 80 at the proximal end of the separate hypotube 14'. The annular second seal 84 protrudes substantially parallel along the longitudinal axis of the main hypotube and extends axially beyond an opening 86 for the main branch guide wire (not shown). Additionally, a third annular seal 88 is shown connected to the first bushing 80. The third seal 88 has a smaller diameter and lies axially and radially inward of the second seal 84. The third seal 88 is also secured to the first bushing 80 of the separate hypotube 14' and tapers radially inward as it extends longitudinally in a direction away from the separate hypotube 14', to envelope the main guide wire 12'.

The integration of the proximal end of the separate hypotube 14' and the distal end of the proximal shaft 70 is shown in FIG. 8. Particularly, the first and second bushings 80, 82 of the hypotube 14' are of a diameter that allows them to fit under or within the particular components of the proximal shaft 70. Specifically, the second bushing 82 of the hypotube 14' is distal to the proximal shaft bushing 72 and is enveloped by the first soft seal 74 of the proximal shaft 70. The first bushing 80 of the hypotube 14' is adjacent to the bushing 72 of the proximal shaft and is enveloped by the proximal shaft 70. With continued reference to FIG. 8, the integrated hypotube 14' and proximal shaft 70 are shown in a freely rotatable position. In this mode, the hypotube 14' rotates freely while the proximal shaft 70 remains fixed. Positive pressure allows the seals 82 and 88 extending from the first bushing 80 of the hypotube 14', to contact the proximal fixed shaft 70 and main guide wire 12' hence sealing the balloon delivery system 10' allowing for all positive pressure to be transferred to the balloon 28'. This provides for expansion of the balloon 28' and deployment of a stent such as previously described. Alternatively, as is shown in FIG. 9 negative pressure applied within the shaft 70 will create contact between the separate hypotube and the seal 74 of the proximal shaft 70. Also, contact will be created at the distal end of the separate hypotube between the soft material and the wire 12' creating a seal there as well. These seals allow for all negative pressure to be transmitted to the balloon allowing for collapse and then removal of the balloon.

Thus, it is apparent that a truly unique feature of the invention is a freely rotating stent assembly that provides a more exact placement of the stent relative to the side branch passage. The invention has been described with reference to the preferred embodiments. Obviously, modifications and alterations will occur to others upon a reading and understanding of this specification. For example, the illustrated embodiments use a balloon to expand the stent although, as briefly noted above, a self expanding or self deploying stent can be used without departing from the features of the present invention. Likewise, using a fixed wire on the distal end of the apparatus is also recognized as being consistent with the features of the present invention. Moreover, the preferred embodiments describe a side branch hypotube, either split or unsplit, that is associated with the side branch guide wire. It will be further appreciated that the side branch guide wire could be carried and/or released in a variety of other ways. The invention is intended to include all such modifications and alterations thereof.

The above disclosure is intended to be illustrative and not exhaustive. This description will suggest many variations and alternatives to one of ordinary skill in this art. All these alternatives and variations are intended to be included within the scope of the claims where the term "comprising" means "including, but not limited to". Those familiar with the art may recognize other equivalents to the specific embodiments described herein which equivalents are also intended to be encompassed by the claims.

Further, the particular features presented in the dependent claims can be combined with each other in other manners within the scope of the invention such that the invention should be recognized as also specifically directed to other embodiments having any other possible combination of the features of the dependent claims. For instance, for purposes of claim publication, any dependent claim which follows should be taken as alternatively written in a multiple dependent form from all prior claims which possess all antecedents referenced in such dependent claim if such multiple dependent format is an accepted format within the jurisdiction (e.g. each claim depending directly from claim 1 should be alternatively taken as depending from all previous claims). In jurisdictions where multiple dependent claim formats are restricted, the following dependent claims should each be also taken as alternatively written in each singly dependent claim format which creates a dependency from a prior antecedent-possessing claim other than the specific claim listed in such dependent claim below. This completes the description of the preferred and alternate embodiments of the invention. Those skilled in the art may recognize other equivalents to the specific embodiment described herein which equivalents are intended to be encompassed by the claims attached hereto.

Claims

CLAIMS:
1. A catheter assembly comprising: an elongate guide member, the elongate guide member extending from a proximal end to a distal end of the catheter assembly; a tubular member disposed about a portion of the elongate guide member, the tubular member rotatable about the elongate guide member; an expandable medical balloon having a proximal end and a distal end, the medical balloon disposed about at least a portion of the tubular member, the proximal end and the distal end of the medical balloon fixedly engaged to the tubular member; and a proximal shaft member, the proximal shaft member disposed about a portion of the elongate guide member, the proximal shaft member having a distal end region, the distal end region being disposed about a proximal end region of the tubular member, the tubular member passively rotatable relative to the proximal shaft.
2. The catheter assembly of claim 1 wherein the tubular member defines an inflation port, the inflation port constructed and arranged to transmit an inflation media to and from the medical balloon from and to the proximal end of the catheter assembly.
3. The catheter assembly of claim 1 wherein the distal end region of the proximal shaft member is sealingly engaged to the proximal end region of the tubular member.
4. The catheter assembly of claim 1 wherein the proximal end region of the tubular member comprises a first bushing and the distal end region of the proximal shaft member comprises a second bushing, the first bushing engaged to the second bushing to form a fluid tight seal between the proximal end region of the tubular member and the distal end region of the proximal shaft member.
5. The catheter assembly of claim 4 wherein the proximal end region of the tubular member further comprises a third bushing, the second bushing positioned between the first bushing and the second bushing.
6. The catheter assembly of claim 3 further comprising a first annular seal, the first annular seal extending from the distal end region of the proximal shaft member to the proximal end region of the tubular member.
7. The catheter assembly of claim 6 wherein the first annular seal tapers from a first end engaged to the distal end region of the proximal shaft member to a narrower second end engaged to the tubular member.
8. The catheter assembly of claim 7 further comprising a second annular seal, the second annular seal extending from the distal end region of the proximal shaft member to the proximal end region of the tubular member, the second annular seal being positioned proximal to the first annular seal.
'9. The catheter assembly of claim 8 further comprising a third annular seal, the third annular seal extending from the proximal end region of the tubular member to the elongate guide member.
10. The catheter assembly of claim 9 wherein the third annular seal tapers from a first end engaged to the proximal end region of the tubular member to a narrower second end engaged to the elongate guide member.
11. The catheter assembly of claim 1 wherein a proximal end region of the tubular member is sealingly engaged to the elongate guide member.
12. The catheter assembly of claim 11 further comprising a third annular seal, the third annular seal extending from the proximal end region of the tubular member to the elongate guide member.
13. The catheter assembly of claim 1 further comprising an expandable and implantable medical device, the expandable and implantable medical device being removably disposed about at least a portion of the medical balloon.
14. A catheter assembly comprising: an elongate guide member, the elongate guide member extending from a proximal end to a distal end of the catheter assembly; a tubular member disposed about a portion the elongate guide member, the tubular member rotatable about the elongate guide member; a medical balloon having a proximal end and a distal end, the medical balloon disposed about at least a portion of the tubular member, the proximal end and the distal end of the medical balloon fixedly engaged to the tubular member; and a proximal shaft member, the proximal shaft member disposed about a portion of the elongate guide member, the proximal shaft member having a distal end region, the distal end region of the proximal shaft member being disposed about a proximal end region of the tubular member, the distal end region of the proximal shaft member and the proximal end region of the tubular member forming a fluid tight seal therebetween, the tubular member being passively rotatable relative to the proximal shaft member.
15. The catheter assembly of claim 14 further comprising a stent, the stent being disposed about at least a portion of the medical balloon, the stent being expanded from a reduced state to an expanded state when the medical balloon is expanded.
16. A catheter assembly comprising: an elongate guide member, the elongate guide member extending from a proximal end to a distal end of the catheter assembly; an inner tubular member, the inner tubular member disposed about a portion of the elongate guide member; an outer tubular member, the outer tubular member disposed about at least a portion of the inner tubular member; a proximal rotatable member and a distal rotatable member, the proximal rotatable member being disposed about a proximal portion of the outer tubular member, the distal rotatable member being disposed about at least one of the distal portion of the inner tubular member and the distal portion of the outer tubular member, the proximal rotatable member forming a slidable and rotatable fluid seal with the proximal portion of the outer tubular member and the distal rotating member forming a slidable and rotatable fluid seal with the at least one of the distal portion of the inner tubular member and the distal portion of the outer tubular member; and a medical balloon expandable between a first state and a second state, the medical balloon having a proximal end and a distal end, the proximal end of the medical balloon being engaged to the proximal rotatable member and the distal end of the medical balloon being engaged to the distal rotatable member.
17. The catheter assembly of claim 16 wherein the proximal portion of the outer tubular member and the inner tubular member define a space, the space defining an inflation lumen.
18. The catheter assembly of claim 17 wherein at least a portion of the outer tubular member underlying the medical balloon defines at least one inflation port, the at least one inflation port in fluid communication with the inflation lumen.
19. The catheter assembly of claim 16 wherein the distal rotatable member is disposed about the distal portion of the outer tubular member.
20. The catheter assembly of claim 19 wherein the distal portion of the outer tubular member is sealingly engaged to the distal portion of the inner tubular member.
21. The catheter assembly of claim 16 further comprising a proximal stop member and a distal stop member, the proximal stop member being fixedly engaged to the proximal portion of the outer tubular member, the distal stop member being fixedly engaged to at least one of the distal portion of the inner tubular member and the distal portion of the outer tubular member.
22. The catheter assembly of claim 21 wherein the proximal stop member is positioned proximally adjacent to the proximal rotatable member and the distal stop member is positioned distally adjacent to the distal rotatable member.
23. The catheter assembly of claim 22 wherein when the medical balloon is expanded from the first position to the second position the proximal rotatable member is moved longitudinally to engage the proximal stop member and distal rotatable member is moved distally to engage the distal stop member
24. The catheter assembly of claim 16 further comprising a secondary tubular member, the secondary tubular member being engaged to an external surface of the medical balloon.
25. The catheter assembly of claim 24 wherein the secondary tubular member has an open position and a closed position, in the closed position the secondary tubular member defining a substantially hollow interior open at both ends, the substantially hollow interior defining secondary lumen, the secondary lumen constructed and arranged to receive a secondary elongate guide member therethrough, in the open position the secondary tubular member defines a longitudinal opening that exposes the secondary lumen thereby releasing the secondary elongate guide member from the secondary tubular member.
26. The catheter assembly of claim 25 wherein the secondary tubular member is disposed about a secondary elongate guide member, the secondary tubular member being moveable relative to the secondary elongate guide member.
27. The catheter assembly of claim 26 further comprising a stent, the stent comprising a substantially hollow tubular member having a plurality of openings therethrough, the stent being disposed about at least a portion of the medical balloon when the stent is in the unexpanded position, the stent being expandable from the unexpanded position to an expanded position, the stent being in the unexpanded position when the balloon is in the first state, the stent being in the expanded position when the medical balloon is in the second state.
28. The catheter assembly of claim 27 wherein the stent is selected from the group consisting of a balloon expandable stent, a self-expanding stent and any combination thereof.
29. The catheter assembly of claim 26 wherein the secondary tubular member is positioned between at least a portion of the stent and the medical balloon.
30. The catheter assembly of claim 29 wherein the secondary elongate guide member exits the secondary tubular member and passes through one of the plurality of openings through the substantially hollow tubular member of the stent.
31. A method of placing a stent at a bifurcation comprising the steps of: advancing a first guide wire through a body lumen to a first branch of a vessel bifurcation; advancing a second guide wire through the body lumen to a second branch of the vessel bifurcation; advancing a catheter assembly to the vessel bifurcation along the first guide wire and a second guide wire, the catheter assembly comprising: a medical balloon disposed about the first guide wire, the medical balloon being freely rotatable about the first guide wire, a tubular member engaged to an external surface of the medical balloon, the tubular member being disposed about the second guide wire, and a stent, the stent being disposed about at least a portion of the medical balloon and the tubular member, the second guide wire passing through at least one opening defined by the stent.
32. A delivery assembly for precisely positioning a stent at a bifurcated passage, the assembly comprising: a first guide wire adapted for receipt into a passage; a side branch guide wire adapted for receipt into a side branch passage; and a stent assembly carried by the first guide wire and operatively associated with the side branch guide wire, the assembly having proximal and distal ends, selectively rotatable relative to the first guide wire whereby the side branch guide wire is properly positioned in the side branch passage.
33. The delivery assembly of claim 32 further comprising an inner hollow member receiving the first guide wire therethrough.
34. The delivery assembly of claim 33 further comprising a balloon received on the inner hollow member for deploying the stent assembly.
35. The delivery assembly of claim 34 wherein the balloon rotates relative to the inner hollow member.
36. The delivery assembly of claim 34 wherein the inner hollow member has an opening that operatively communicates with an interior of the balloon.
37. The delivery assembly of claim 33 further comprising first and second fixed members disposed in axially spaced relation on the inner member.
38. The delivery assembly of claim 37 further comprising a balloon axially received between the fixed members.
39. The delivery assembly of claim 33 further comprising first and second rotatable members received on the inner hollow member, the rotatable members secured to first and second ends of a balloon to permit selective rotation of the balloon and passively orient the side branch guide wire in the side branch passage.
40. The delivery assembly of claim 39 wherein the inner hollow member forms a fluid passage that conveys fluid to the balloon.
41. The delivery assembly of claim 32 further comprising a carrier for the side branch guide wire carried on the balloon.
42. The delivery assembly of claim 41 wherein the carrier includes a longitudinal slit that selectively opens in response to inflation of the balloon for releasing the side branch guide wire.
43. A method of delivering a stent to a stenosed bifurcated passage comprising the steps of: inserting a main guide wire, balloon, and stent in a passage; inserting a side branch guide wire at a side branch passage; and allowing the stent to rotate relative to the main guide wire to properly orient same.
44. The delivery method of claim 43 comprising inflating a balloon to deploy the stent.
45. The delivery method of claim 44 further comprising releasing the side branch guide wire in response to inflating the balloon.
46. The assembly of claim 45 wherein the releasing step includes opening a side tube secured to the balloon to release the side branch guide wire.
47. A stent delivery assembly for a bifurcated passage comprising: a first guide wire for receipt in a main branch of the bifurcated passage; a second guide wire for receipt in a side branch of the bifurcated passage; and a stent carried by the first guide wire and operatively associated with the second guide wire, the stent rotatably mounted relative to the first guide wire so that insertion of the second guide wire into the side branch properly orients the stent.
48. The assembly of claim 47 farther comprising a balloon rotatably received on the first guide wire.
49. The assembly of claim 49 further comprising first and second rotating members received over the first guide wire and receiving corresponding first and second ends of the balloon to permit selective rotation of the balloon and passively orient the side branch guide wire via the side branch passage.
50. The assembly of claim 48 wherein the stent is self-expanding.
51. The assembly of claim 47 further comprising a balloon rotatably received on the fast guide wire for selectively expanding the stent and a side branch guide wire Carrier.
PCT/US2002/026736 2001-08-23 2002-08-22 Rotating stent delivery system for side branch access and protection and method of using same. WO2003017872A9 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US31446701 true 2001-08-23 2001-08-23
US60/314,467 2001-08-23

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE2002629852 DE60229852D1 (en) 2001-08-23 2002-08-22 Rotating stent delivery system to place into a side branch and protection
JP2003522396A JP4460289B2 (en) 2001-08-23 2002-08-22 Catheter assembly
CA 2457860 CA2457860C (en) 2001-08-23 2002-08-22 Rotating stent delivery system for side branch access and protection and method of using same
EP20020753511 EP1418863B1 (en) 2001-08-23 2002-08-22 Rotating stent delivery system for side branch access and protection

Publications (2)

Publication Number Publication Date
WO2003017872A1 true true WO2003017872A1 (en) 2003-03-06
WO2003017872A9 true WO2003017872A9 (en) 2003-12-18

Family

ID=23220060

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/026736 WO2003017872A9 (en) 2001-08-23 2002-08-22 Rotating stent delivery system for side branch access and protection and method of using same.

Country Status (7)

Country Link
US (2) US7563270B2 (en)
JP (1) JP4460289B2 (en)
CA (1) CA2457860C (en)
DE (1) DE60229852D1 (en)
EP (1) EP1418863B1 (en)
ES (1) ES2319621T3 (en)
WO (1) WO2003017872A9 (en)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004075792A1 (en) * 2003-02-27 2004-09-10 Boston Scientific Limited Stent delivery system with a balloon catheter surrounded by a rotating sheath
WO2005025458A1 (en) * 2003-09-08 2005-03-24 Boston Scientific Limited Rotating expandable balloon and sheath for stent delivery to bifurcated vessel
EP1551333A2 (en) * 2002-06-13 2005-07-13 Existent, Inc. Guidewire system
WO2005067818A1 (en) * 2003-12-29 2005-07-28 Boston Scientific Limited Rotating balloon expandable sheath bifurcation delivery system
WO2005070334A1 (en) * 2004-01-13 2005-08-04 Boston Scientific Limited Bifurcated stent delivery system
WO2005079902A1 (en) * 2004-02-18 2005-09-01 Boston Scientific Limited Multi-stent delivery system
WO2005082280A1 (en) * 2004-02-24 2005-09-09 Boston Scientific Limited Rotatable catheter assembly
WO2005122958A1 (en) * 2004-06-08 2005-12-29 Boston Scientific Limited Bifurcated stent delivery system
WO2006020457A1 (en) * 2004-08-10 2006-02-23 Boston Scientific Limited Rotatable catheter assembly
WO2006098788A1 (en) * 2005-03-14 2006-09-21 Boston Scientific Limited Bifurcation stent delivery system with rotational coupling
WO2007061792A3 (en) * 2005-11-18 2007-12-06 Boston Scient Ltd Bifurcation stent delivery system
US7563270B2 (en) 2001-08-23 2009-07-21 Gumm Darrel C Rotating stent delivery system for side branch access and protection and method of using same
US7635383B2 (en) 2004-09-28 2009-12-22 Boston Scientific Scimed, Inc. Rotating stent delivery system for side branch access and protection and method of using same
US8292940B2 (en) 2009-02-11 2012-10-23 Boston Scientific Scimed, Inc. Medical device having a rotatable shaft

Families Citing this family (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6835203B1 (en) 1996-11-04 2004-12-28 Advanced Stent Technologies, Inc. Extendible stent apparatus
DE69736676D1 (en) * 1996-11-04 2006-10-26 Advanced Stent Tech Inc Expandable stent double
US7341598B2 (en) 1999-01-13 2008-03-11 Boston Scientific Scimed, Inc. Stent with protruding branch portion for bifurcated vessels
US7220275B2 (en) * 1996-11-04 2007-05-22 Advanced Stent Technologies, Inc. Stent with protruding branch portion for bifurcated vessels
US8298280B2 (en) 2003-08-21 2012-10-30 Boston Scientific Scimed, Inc. Stent with protruding branch portion for bifurcated vessels
US6325826B1 (en) 1998-01-14 2001-12-04 Advanced Stent Technologies, Inc. Extendible stent apparatus
US6599316B2 (en) * 1996-11-04 2003-07-29 Advanced Stent Technologies, Inc. Extendible stent apparatus
US8257425B2 (en) * 1999-01-13 2012-09-04 Boston Scientific Scimed, Inc. Stent with protruding branch portion for bifurcated vessels
US8007528B2 (en) * 2004-03-17 2011-08-30 Boston Scientific Scimed, Inc. Bifurcated stent
CA2360551C (en) * 1999-01-27 2009-12-22 Scimed Life Systems, Inc. Bifurcation stent delivery system
CN1409622A (en) * 1999-09-23 2003-04-09 先进扩张技术公司 Bifurcation stent system and method
US7101391B2 (en) * 2000-09-18 2006-09-05 Inflow Dynamics Inc. Primarily niobium stent
WO2002067653A3 (en) 2001-02-26 2003-03-13 Scimed Life Systems Inc Bifurcated stent and delivery system
US20030078614A1 (en) * 2001-10-18 2003-04-24 Amr Salahieh Vascular embolic filter devices and methods of use therefor
US7166120B2 (en) * 2002-07-12 2007-01-23 Ev3 Inc. Catheter with occluding cuff
KR100893070B1 (en) * 2002-09-19 2004-03-24 엘지전자 주식회사 Method and apparatus for providing and receiving multicast service in a radio communication system
US7066905B2 (en) * 2002-11-13 2006-06-27 Squire James C Method and apparatus for accurate positioning of a dual balloon catheter
US20040143286A1 (en) 2003-01-17 2004-07-22 Johnson Eric G. Catheter with disruptable guidewire channel
US20040225345A1 (en) * 2003-05-05 2004-11-11 Fischell Robert E. Means and method for stenting bifurcated vessels
US9427340B2 (en) * 2004-12-14 2016-08-30 Boston Scientific Scimed, Inc. Stent with protruding branch portion for bifurcated vessels
US7225518B2 (en) * 2004-02-23 2007-06-05 Boston Scientific Scimed, Inc. Apparatus for crimping a stent assembly
US7753951B2 (en) * 2004-03-04 2010-07-13 Y Med, Inc. Vessel treatment devices
US9050437B2 (en) * 2004-03-04 2015-06-09 YMED, Inc. Positioning device for ostial lesions
US7780715B2 (en) * 2004-03-04 2010-08-24 Y Med, Inc. Vessel treatment devices
US20050209673A1 (en) * 2004-03-04 2005-09-22 Y Med Inc. Bifurcation stent delivery devices
US7766951B2 (en) * 2004-03-04 2010-08-03 Y Med, Inc. Vessel treatment devices
US8486025B2 (en) * 2006-05-11 2013-07-16 Ronald J. Solar Systems and methods for treating a vessel using focused force
US7901378B2 (en) * 2006-05-11 2011-03-08 Y-Med, Inc. Systems and methods for treating a vessel using focused force
EP2298192B1 (en) * 2004-04-22 2012-09-12 Angioslide Ltd. Catheter with balloon
WO2005122959A3 (en) 2004-06-08 2007-03-15 Advanced Stent Tech Inc Stent with protruding branch portion for bifurcated vessels
US20060064064A1 (en) * 2004-09-17 2006-03-23 Jang G D Two-step/dual-diameter balloon angioplasty catheter for bifurcation and side-branch vascular anatomy
US20080188803A1 (en) * 2005-02-03 2008-08-07 Jang G David Triple-profile balloon catheter
US8608789B2 (en) * 2005-05-24 2013-12-17 Trireme Medical, Inc. Delivery system for bifurcation stents
US8480728B2 (en) * 2005-05-26 2013-07-09 Boston Scientific Scimed, Inc. Stent side branch deployment initiation geometry
US8317855B2 (en) * 2005-05-26 2012-11-27 Boston Scientific Scimed, Inc. Crimpable and expandable side branch cell
US20060271161A1 (en) * 2005-05-26 2006-11-30 Boston Scientific Scimed, Inc. Selective treatment of stent side branch petals
US7485140B2 (en) * 2005-06-17 2009-02-03 Boston Scientific Scimed, Inc. Bifurcation stent assembly
US7419563B2 (en) * 2005-06-23 2008-09-02 Boston Scientific Scimed, Inc. Methods of making medical devices
US9439662B2 (en) 2005-07-05 2016-09-13 Angioslide Ltd. Balloon catheter
US8556851B2 (en) 2005-07-05 2013-10-15 Angioslide Ltd. Balloon catheter
US7731741B2 (en) 2005-09-08 2010-06-08 Boston Scientific Scimed, Inc. Inflatable bifurcation stent
US8043366B2 (en) * 2005-09-08 2011-10-25 Boston Scientific Scimed, Inc. Overlapping stent
US8038706B2 (en) * 2005-09-08 2011-10-18 Boston Scientific Scimed, Inc. Crown stent assembly
US8192477B2 (en) * 2005-11-14 2012-06-05 Boston Scientific Scimed, Inc. Twisting bifurcation delivery system
US20070112418A1 (en) * 2005-11-14 2007-05-17 Boston Scientific Scimed, Inc. Stent with spiral side-branch support designs
US8343211B2 (en) * 2005-12-14 2013-01-01 Boston Scientific Scimed, Inc. Connectors for bifurcated stent
US8435284B2 (en) * 2005-12-14 2013-05-07 Boston Scientific Scimed, Inc. Telescoping bifurcated stent
US7540881B2 (en) 2005-12-22 2009-06-02 Boston Scientific Scimed, Inc. Bifurcation stent pattern
EP1962940A4 (en) * 2005-12-23 2011-05-25 Bard Inc C R Balloon catheter with centralized vent hole
US20070208419A1 (en) * 2006-03-06 2007-09-06 Boston Scientific Scimed, Inc. Bifurcation stent with uniform side branch projection
US7833264B2 (en) * 2006-03-06 2010-11-16 Boston Scientific Scimed, Inc. Bifurcated stent
US20070208415A1 (en) * 2006-03-06 2007-09-06 Kevin Grotheim Bifurcated stent with controlled drug delivery
US20070208414A1 (en) * 2006-03-06 2007-09-06 Shawn Sorenson Tapered strength rings on a bifurcated stent petal
US20070208411A1 (en) * 2006-03-06 2007-09-06 Boston Scientific Scimed, Inc. Bifurcated stent with surface area gradient
US8298278B2 (en) * 2006-03-07 2012-10-30 Boston Scientific Scimed, Inc. Bifurcated stent with improvement securement
US9757260B2 (en) * 2006-03-30 2017-09-12 Medtronic Vascular, Inc. Prosthesis with guide lumen
US20070233233A1 (en) * 2006-03-31 2007-10-04 Boston Scientific Scimed, Inc Tethered expansion columns for controlled stent expansion
US8403977B2 (en) * 2006-05-04 2013-03-26 Cook Medical Technologies Llc Self-orienting delivery system
WO2008002441A3 (en) 2006-06-23 2008-05-29 Boston Scient Scimed Inc Bifurcated stent with twisted hinges
WO2008021570A3 (en) * 2006-08-18 2008-04-10 Abbott Lab Bifurcation stent delivery catheter and method
US8246670B2 (en) * 2006-08-23 2012-08-21 Abbott Cardiovascular Systems Inc. Catheter system and method for delivering medical devices
US8216267B2 (en) 2006-09-12 2012-07-10 Boston Scientific Scimed, Inc. Multilayer balloon for bifurcated stent delivery and methods of making and using the same
US7951191B2 (en) 2006-10-10 2011-05-31 Boston Scientific Scimed, Inc. Bifurcated stent with entire circumferential petal
US8206429B2 (en) 2006-11-02 2012-06-26 Boston Scientific Scimed, Inc. Adjustable bifurcation catheter incorporating electroactive polymer and methods of making and using the same
US7842082B2 (en) 2006-11-16 2010-11-30 Boston Scientific Scimed, Inc. Bifurcated stent
US7959668B2 (en) 2007-01-16 2011-06-14 Boston Scientific Scimed, Inc. Bifurcated stent
US8118861B2 (en) * 2007-03-28 2012-02-21 Boston Scientific Scimed, Inc. Bifurcation stent and balloon assemblies
US8647376B2 (en) * 2007-03-30 2014-02-11 Boston Scientific Scimed, Inc. Balloon fold design for deployment of bifurcated stent petal architecture
US9358142B2 (en) * 2007-04-24 2016-06-07 W. L. Gore & Associates, Inc. Catheter having guidewire channel
US8273115B2 (en) * 2007-04-24 2012-09-25 W. L. Gore & Associates, Inc. Side branched endoluminal prostheses and methods of delivery thereof
US20090054836A1 (en) * 2007-08-20 2009-02-26 Medtronic Vascular, Inc. Method and Apparatus for Treating Stenoses at Bifurcated Regions
US7959669B2 (en) 2007-09-12 2011-06-14 Boston Scientific Scimed, Inc. Bifurcated stent with open ended side branch support
US7833266B2 (en) 2007-11-28 2010-11-16 Boston Scientific Scimed, Inc. Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment
WO2009082718A1 (en) * 2007-12-21 2009-07-02 Feinstein Ara J Devices, systems, and methods for repair of vascular defects
US8277501B2 (en) 2007-12-21 2012-10-02 Boston Scientific Scimed, Inc. Bi-stable bifurcated stent petal geometry
WO2009088953A3 (en) 2007-12-31 2009-10-29 Boston Scientific Scimed Inc. Bifurcation stent delivery system and methods
EP2460477A1 (en) 2008-04-21 2012-06-06 NFOCUS Neuromedical, Inc. Braid-ball embolic devices and delivery systems
US8333003B2 (en) 2008-05-19 2012-12-18 Boston Scientific Scimed, Inc. Bifurcation stent crimping systems and methods
US8932340B2 (en) 2008-05-29 2015-01-13 Boston Scientific Scimed, Inc. Bifurcated stent and delivery system
US20090299455A1 (en) * 2008-05-29 2009-12-03 Sutermeister Derek C Rotatable catheter assembly
US8827951B2 (en) 2008-07-02 2014-09-09 Doron Besser Balloon catheter system and methods of use thereof
US8133199B2 (en) 2008-08-27 2012-03-13 Boston Scientific Scimed, Inc. Electroactive polymer activation system for a medical device
US9358140B1 (en) 2009-11-18 2016-06-07 Aneuclose Llc Stent with outer member to embolize an aneurysm
WO2011089599A1 (en) 2010-01-19 2011-07-28 Angioslide Ltd. Balloon catheter system and methods of making and use thereof
EP2528542A4 (en) 2010-01-28 2013-07-03 Covidien Lp Vascular remodeling device
EP2672900B1 (en) 2011-02-11 2017-11-01 Covidien LP Two-stage deployment aneurysm embolization devices
US20140296704A1 (en) 2011-06-07 2014-10-02 Koninklijke Philips N.V. Rotational position determination apparatus
US8574283B1 (en) * 2011-08-30 2013-11-05 Suraj Govind Kamat Deployment of stents within bifurcated vessels
US9314248B2 (en) 2012-11-06 2016-04-19 Covidien Lp Multi-pivot thrombectomy device
US9295571B2 (en) * 2013-01-17 2016-03-29 Covidien Lp Methods and apparatus for luminal stenting
US9463105B2 (en) 2013-03-14 2016-10-11 Covidien Lp Methods and apparatus for luminal stenting

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5749825A (en) 1996-09-18 1998-05-12 Isostent, Inc. Means method for treatment of stenosed arterial bifurcations
US6221090B1 (en) * 1997-08-13 2001-04-24 Advanced Cardiovascular Systems, Inc. Stent delivery assembly
US20020072755A1 (en) * 2000-12-08 2002-06-13 Bigus Stephen J. Catheter with rotatable balloon

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4498923A (en) * 1981-03-20 1985-02-12 General Electric Company Method for producing eutectics as thin films using a quartz lamp as a heat source in a line heater
FR2512665B3 (en) * 1981-09-12 1984-12-07 Wolf Gmbh Richard
US4601701A (en) * 1985-02-25 1986-07-22 Argon Medical Corp. Multi-purpose multi-lumen catheter
US5449343A (en) 1985-07-30 1995-09-12 Advanced Cardiovascular Systems, Inc. Steerable dilatation catheter
US4998923A (en) 1988-08-11 1991-03-12 Advanced Cardiovascular Systems, Inc. Steerable dilatation catheter
US4733665C2 (en) * 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US4771782A (en) * 1986-11-14 1988-09-20 Millar Instruments, Inc. Method and assembly for introducing multiple catheters into a biological vessel
US4988356A (en) * 1987-02-27 1991-01-29 C. R. Bard, Inc. Catheter and guidewire exchange system
US4769005A (en) * 1987-08-06 1988-09-06 Robert Ginsburg Selective catheter guide
US5019085A (en) * 1988-10-25 1991-05-28 Cordis Corporation Apparatus and method for placement of a stent within a subject vessel
US4913141A (en) * 1988-10-25 1990-04-03 Cordis Corporation Apparatus and method for placement of a stent within a subject vessel
US4994071A (en) * 1989-05-22 1991-02-19 Cordis Corporation Bifurcating stent apparatus and method
US5209728B1 (en) * 1989-11-02 1998-04-14 Danforth Biomedical Inc Low profile high performance interventional catheters
US5415649A (en) * 1990-10-31 1995-05-16 Kao Corporation Disposable diapers
EP0492361B1 (en) * 1990-12-21 1996-07-31 Advanced Cardiovascular Systems, Inc. Fixed-wire dilatation catheter with rotatable balloon assembly
CA2060067A1 (en) * 1991-01-28 1992-07-29 Lilip Lau Stent delivery system
US5329923A (en) * 1991-02-15 1994-07-19 Lundquist Ingemar H Torquable catheter
US5824044A (en) * 1994-05-12 1998-10-20 Endovascular Technologies, Inc. Bifurcated multicapsule intraluminal grafting system
US5454788A (en) * 1991-04-24 1995-10-03 Baxter International Inc. Exchangeable integrated-wire balloon catheter
FR2678508B1 (en) 1991-07-04 1998-01-30 Celsa Lg Device for reinforcing the body vessels.
US5316023A (en) * 1992-01-08 1994-05-31 Expandable Grafts Partnership Method for bilateral intra-aortic bypass
US5348537A (en) * 1992-07-15 1994-09-20 Advanced Cardiovascular Systems, Inc. Catheter with intraluminal sealing element
US5634901A (en) * 1992-11-02 1997-06-03 Localmed, Inc. Method of using a catheter sleeve
US5318535A (en) * 1993-06-21 1994-06-07 Baxter International Inc. Low-profile dual-lumen perfusion balloon catheter with axially movable inner guide sheath
US5609627A (en) * 1994-02-09 1997-03-11 Boston Scientific Technology, Inc. Method for delivering a bifurcated endoluminal prosthesis
US6331188B1 (en) * 1994-08-31 2001-12-18 Gore Enterprise Holdings, Inc. Exterior supported self-expanding stent-graft
US6015429A (en) * 1994-09-08 2000-01-18 Gore Enterprise Holdings, Inc. Procedures for introducing stents and stent-grafts
US5779688A (en) * 1994-10-28 1998-07-14 Intella Interventional Systems, Inc. Low profile balloon-on-a-wire catheter with shapeable and/or deflectable tip and method
NL9500094A (en) * 1995-01-19 1996-09-02 Industrial Res Bv Y-shaped stent and method of the locations thereof.
US5643278A (en) * 1995-04-06 1997-07-01 Leocor, Inc. Stent delivery system
US6322548B1 (en) * 1995-05-10 2001-11-27 Eclipse Surgical Technologies Delivery catheter system for heart chamber
JPH11507567A (en) * 1995-06-08 1999-07-06 バード ギャルウェイ リミティド Conduit within the stent
US6027460A (en) * 1995-09-14 2000-02-22 Shturman Cardiology Systems, Inc. Rotatable intravascular apparatus
US6436104B2 (en) * 1996-01-26 2002-08-20 Cordis Corporation Bifurcated axially flexible stent
US5632736A (en) 1996-02-29 1997-05-27 Block; James C. Fluid voiding apparatus
US6533805B1 (en) * 1996-04-01 2003-03-18 General Surgical Innovations, Inc. Prosthesis and method for deployment within a body lumen
US5755734A (en) * 1996-05-03 1998-05-26 Medinol Ltd. Bifurcated stent and method of making same
CA2175720C (en) * 1996-05-03 2011-11-29 Ian M. Penn Bifurcated stent and method for the manufacture and delivery of same
US6056775A (en) * 1996-05-31 2000-05-02 Ave Galway Limited Bifurcated endovascular stents and method and apparatus for their placement
US5697971A (en) * 1996-06-11 1997-12-16 Fischell; Robert E. Multi-cell stent with cells having differing characteristics
US5797952A (en) * 1996-06-21 1998-08-25 Localmed, Inc. System and method for delivering helical stents
US5968068A (en) * 1996-09-12 1999-10-19 Baxter International Inc. Endovascular delivery system
US5725519A (en) * 1996-09-30 1998-03-10 Medtronic Instent Israel Ltd. Stent loading device for a balloon catheter
US5755778A (en) * 1996-10-16 1998-05-26 Nitinol Medical Technologies, Inc. Anastomosis device
US6884258B2 (en) * 1999-06-04 2005-04-26 Advanced Stent Technologies, Inc. Bifurcation lesion stent delivery using multiple guidewires
US6596020B2 (en) * 1996-11-04 2003-07-22 Advanced Stent Technologies, Inc. Method of delivering a stent with a side opening
US6352561B1 (en) * 1996-12-23 2002-03-05 W. L. Gore & Associates Implant deployment apparatus
DE29701758U1 (en) 1997-02-01 1997-03-27 Jomed Implantate Gmbh Radially expandable stent for implantation in a body vessel, in particular in the region of a vessel bifurcation
US5720735A (en) * 1997-02-12 1998-02-24 Dorros; Gerald Bifurcated endovascular catheter
US6071286A (en) * 1997-02-19 2000-06-06 Mawad; Michel E. Combination angioplasty balloon/stent deployment device
US6090128A (en) * 1997-02-20 2000-07-18 Endologix, Inc. Bifurcated vascular graft deployment device
US6096073A (en) * 1997-02-25 2000-08-01 Scimed Life Systems, Inc. Method of deploying a stent at a lesion site located at a bifurcation in a parent vessel
US5824055A (en) * 1997-03-25 1998-10-20 Endotex Interventional Systems, Inc. Stent graft delivery system and methods of use
DE29708803U1 (en) * 1997-05-17 1997-07-31 Jomed Implantate Gmbh Radially expandable stent for implantation in a body vessel in the area of ​​a vessel bifurcation
US6165195A (en) * 1997-08-13 2000-12-26 Advanced Cardiovascylar Systems, Inc. Stent and catheter assembly and method for treating bifurcations
US6361544B1 (en) * 1997-08-13 2002-03-26 Advanced Cardiovascular Systems, Inc. Stent and catheter assembly and method for treating bifurcations
US6387120B2 (en) * 1999-12-09 2002-05-14 Advanced Cardiovascular Systems, Inc. Stent and catheter assembly and method for treating bifurcations
US6056722A (en) * 1997-09-18 2000-05-02 Iowa-India Investments Company Limited Of Douglas Delivery mechanism for balloons, drugs, stents and other physical/mechanical agents and methods of use
US6520988B1 (en) * 1997-09-24 2003-02-18 Medtronic Ave, Inc. Endolumenal prosthesis and method of use in bifurcation regions of body lumens
US5961548A (en) * 1997-11-18 1999-10-05 Shmulewitz; Ascher Bifurcated two-part graft and methods of implantation
US6099497A (en) * 1998-03-05 2000-08-08 Scimed Life Systems, Inc. Dilatation and stent delivery system for bifurcation lesions
US6117117A (en) * 1998-08-24 2000-09-12 Advanced Cardiovascular Systems, Inc. Bifurcated catheter assembly
US6514281B1 (en) * 1998-09-04 2003-02-04 Scimed Life Systems, Inc. System for delivering bifurcation stents
US6368345B1 (en) * 1998-09-30 2002-04-09 Edwards Lifesciences Corporation Methods and apparatus for intraluminal placement of a bifurcated intraluminal garafat
US6187036B1 (en) * 1998-12-11 2001-02-13 Endologix, Inc. Endoluminal vascular prosthesis
US6319275B1 (en) * 1999-04-07 2001-11-20 Medtronic Ave, Inc. Endolumenal prosthesis delivery assembly and method of use
US6190360B1 (en) * 1999-04-09 2001-02-20 Endotex Interventional System Stent delivery handle
US6290673B1 (en) * 1999-05-20 2001-09-18 Conor Medsystems, Inc. Expandable medical device delivery system and method
US6246914B1 (en) * 1999-08-12 2001-06-12 Irvine Biomedical, Inc. High torque catheter and methods thereof
WO2001035715A2 (en) * 1999-11-18 2001-05-25 Petrus Besselink Method for placing bifurcated stents
US6375660B1 (en) * 1999-11-22 2002-04-23 Cordis Corporation Stent delivery system with a fixed guide wire
US6224587B1 (en) * 1999-11-22 2001-05-01 C.R. Bard, Inc. Steerable catheter
US6280466B1 (en) * 1999-12-03 2001-08-28 Teramed Inc. Endovascular graft system
US6210431B1 (en) * 1999-12-10 2001-04-03 John A. Power Ostial bifurcation lesion stenting catheter
US6254593B1 (en) * 1999-12-10 2001-07-03 Advanced Cardiovascular Systems, Inc. Bifurcated stent delivery system having retractable sheath
US6361555B1 (en) 1999-12-15 2002-03-26 Advanced Cardiovascular Systems, Inc. Stent and stent delivery assembly and method of use
US6443926B1 (en) * 2000-02-01 2002-09-03 Harold D. Kletschka Embolic protection device having expandable trap
US6589262B1 (en) * 2000-03-31 2003-07-08 Medamicus, Inc. Locking catheter introducing system
US6629981B2 (en) * 2000-07-06 2003-10-07 Endocare, Inc. Stent delivery system
US6475166B1 (en) * 2000-08-18 2002-11-05 Endovascular Technologies, Inc. Guidewire placement system for delivery of an aneurysm graft limb
US6540179B2 (en) * 2000-12-15 2003-04-01 Lockheed Martin Corporation In-flight loadable and refuelable unmanned aircraft system for continuous flight
EP1382367B1 (en) * 2001-02-27 2007-10-31 Kabushikikaisha Igaki Iryo Sekkei Stent holding member and stent feeding system
CA2457860C (en) 2001-08-23 2010-03-16 Darrel C. Gumm Rotating stent delivery system for side branch access and protection and method of using same
WO2003055414A1 (en) 2001-10-18 2003-07-10 Advanced Stent Technologies, Inc. Stent for vessel support, coverage and side branch accessibility
US7070613B2 (en) * 2002-01-04 2006-07-04 Boston Scientific Scimed, Inc. Non-compliant balloon with compliant top-layer to protect coated stents during expansion
US7314480B2 (en) 2003-02-27 2008-01-01 Boston Scientific Scimed, Inc. Rotating balloon expandable sheath bifurcation delivery
US7367989B2 (en) 2003-02-27 2008-05-06 Scimed Life Systems, Inc. Rotating balloon expandable sheath bifurcation delivery
US7686841B2 (en) 2003-12-29 2010-03-30 Boston Scientific Scimed, Inc. Rotating balloon expandable sheath bifurcation delivery system
US7922753B2 (en) 2004-01-13 2011-04-12 Boston Scientific Scimed, Inc. Bifurcated stent delivery system
US8012192B2 (en) 2004-02-18 2011-09-06 Boston Scientific Scimed, Inc. Multi-stent delivery system
US7225518B2 (en) 2004-02-23 2007-06-05 Boston Scientific Scimed, Inc. Apparatus for crimping a stent assembly
US20050273149A1 (en) 2004-06-08 2005-12-08 Tran Thomas T Bifurcated stent delivery system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5749825A (en) 1996-09-18 1998-05-12 Isostent, Inc. Means method for treatment of stenosed arterial bifurcations
US6221090B1 (en) * 1997-08-13 2001-04-24 Advanced Cardiovascular Systems, Inc. Stent delivery assembly
US20020072755A1 (en) * 2000-12-08 2002-06-13 Bigus Stephen J. Catheter with rotatable balloon

Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7563270B2 (en) 2001-08-23 2009-07-21 Gumm Darrel C Rotating stent delivery system for side branch access and protection and method of using same
US8211137B2 (en) 2001-08-23 2012-07-03 Gumm Darrel C Rotating stent delivery system for side branch access and protection and method of using same
EP1551333A2 (en) * 2002-06-13 2005-07-13 Existent, Inc. Guidewire system
US7993389B2 (en) 2002-06-13 2011-08-09 Existent Inc. Guidewire system
EP1551333A4 (en) * 2002-06-13 2010-01-06 Existent Inc Guidewire system
WO2004075792A1 (en) * 2003-02-27 2004-09-10 Boston Scientific Limited Stent delivery system with a balloon catheter surrounded by a rotating sheath
WO2005025458A1 (en) * 2003-09-08 2005-03-24 Boston Scientific Limited Rotating expandable balloon and sheath for stent delivery to bifurcated vessel
JP2007504887A (en) * 2003-09-08 2007-03-08 ボストン サイエンティフィック リミテッド Expandable balloon and sheath to rotate for a stent delivery into the branch pipe
JP4741494B2 (en) * 2003-09-08 2011-08-03 ボストン サイエンティフィック リミテッド The catheter assembly for stent delivery into the branch pipe
WO2005067818A1 (en) * 2003-12-29 2005-07-28 Boston Scientific Limited Rotating balloon expandable sheath bifurcation delivery system
JP4833858B2 (en) * 2004-01-13 2011-12-07 ボストン サイエンティフィック リミテッド A method of forming a catheter assembly and a rotating sheath for use therein
WO2005070334A1 (en) * 2004-01-13 2005-08-04 Boston Scientific Limited Bifurcated stent delivery system
JP4833865B2 (en) * 2004-02-18 2011-12-07 ボストン サイエンティフィック リミテッド Catheter assembly
WO2005079902A1 (en) * 2004-02-18 2005-09-01 Boston Scientific Limited Multi-stent delivery system
JP2007522907A (en) * 2004-02-24 2007-08-16 ボストン サイエンティフィック リミテッド Rotary catheter assembly
JP4672719B2 (en) * 2004-02-24 2011-04-20 ボストン サイエンティフィック リミテッド Rotary catheter assembly
EP2165677A1 (en) * 2004-02-24 2010-03-24 Boston Scientific Limited Rotatable catheter assembly
WO2005082280A1 (en) * 2004-02-24 2005-09-09 Boston Scientific Limited Rotatable catheter assembly
WO2005122958A1 (en) * 2004-06-08 2005-12-29 Boston Scientific Limited Bifurcated stent delivery system
JP2008501479A (en) * 2004-06-08 2008-01-24 ボストン サイエンティフィック リミテッド Bifurcated stent delivery system
WO2006020457A1 (en) * 2004-08-10 2006-02-23 Boston Scientific Limited Rotatable catheter assembly
JP2008509733A (en) * 2004-08-10 2008-04-03 ボストン サイエンティフィック リミテッド Rotatable catheter assembly
US7635383B2 (en) 2004-09-28 2009-12-22 Boston Scientific Scimed, Inc. Rotating stent delivery system for side branch access and protection and method of using same
US8657868B2 (en) 2004-09-28 2014-02-25 Boston Scientific Scimed, Inc. Rotating stent delivery system for side branch access and protection and method of using same
US8152830B2 (en) 2004-09-28 2012-04-10 Boston Scientific Scimed, Inc. Rotating stent delivery system for side branch access and protection and method of using same
US9050207B2 (en) 2004-09-28 2015-06-09 Boston Scientific Scimed, Inc. Rotating stent delivery system for side branch access and protection and method of using same
US8353944B2 (en) 2005-03-14 2013-01-15 Boston Scientific Scimed, Inc. Bifurcation delivery system
WO2006098788A1 (en) * 2005-03-14 2006-09-21 Boston Scientific Limited Bifurcation stent delivery system with rotational coupling
WO2007061792A3 (en) * 2005-11-18 2007-12-06 Boston Scient Ltd Bifurcation stent delivery system
US8292940B2 (en) 2009-02-11 2012-10-23 Boston Scientific Scimed, Inc. Medical device having a rotatable shaft

Also Published As

Publication number Publication date Type
DE60229852D1 (en) 2008-12-24 grant
JP4460289B2 (en) 2010-05-12 grant
CA2457860A1 (en) 2003-03-06 application
ES2319621T3 (en) 2009-05-11 grant
EP1418863B1 (en) 2008-11-12 grant
US7563270B2 (en) 2009-07-21 grant
WO2003017872A9 (en) 2003-12-18 application
EP1418863A1 (en) 2004-05-19 application
JP2005500126A (en) 2005-01-06 application
US8211137B2 (en) 2012-07-03 grant
US20030055483A1 (en) 2003-03-20 application
CA2457860C (en) 2010-03-16 grant
US20100036390A1 (en) 2010-02-11 application

Similar Documents

Publication Publication Date Title
US6143016A (en) Sheath and method of use for a stent delivery system
US5344426A (en) Method and system for stent delivery
US6527791B2 (en) Emboli capturing device
US6117117A (en) Bifurcated catheter assembly
US5242399A (en) Method and system for stent delivery
US5478349A (en) Placement of endoprostheses and stents
US7582111B2 (en) Steep-taper flared stents and apparatus and methods for delivering them
US6027519A (en) Catheter with expandable multiband segment
US6110180A (en) System for removably securing a stent on a catheter assembly and method of use
US6383212B2 (en) Balloon catheter and stent deploying catheter system
US6790224B2 (en) Medical devices
US4923464A (en) Percutaneously deliverable intravascular reconstruction prosthesis
US6027508A (en) Stent retrieval device
US6042589A (en) Reversible-action endoprosthesis delivery device
US5634928A (en) Integrated dual-function catheter system and method for balloon angioplasty and stent delivery
US6319275B1 (en) Endolumenal prosthesis delivery assembly and method of use
US6458151B1 (en) Ostial stent positioning device and method
US7131986B2 (en) Catheter having exchangeable balloon
US7344557B2 (en) Catheter balloon systems and methods
US6443979B1 (en) Expandable stent delivery sheath and method of use
US20050021070A1 (en) Methods and apparatus for manipulating vascular prostheses
US6761734B2 (en) Segmented balloon catheter for stenting bifurcation lesions
US6136011A (en) Stent delivery system and method of use
US5116318A (en) Dilatation balloon within an elastic sleeve
US20030236563A1 (en) Stent delivery catheter with retention bands

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS JP KE KG KP KR LC LK LR LS LT LU LV MA MD MG MN MW MX MZ NO NZ OM PH PL PT RU SD SE SG SI SK SL TJ TM TN TR TZ UA UG UZ VC VN YU ZA ZM

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
COP Corrected version of pamphlet

Free format text: PAGES 1/5-5/5, DRAWINGS, REPLACED BY NEW PAGES 1/6-6/6; DUE TO LATE TRANSMITTAL BY THE RECEIVING OFFICE

WWE Wipo information: entry into national phase

Ref document number: 2457860

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2003522396

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2002753511

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2002753511

Country of ref document: EP