WO2003013692A1 - Appareil de separation et procede de fabrication d'un appareil de separation - Google Patents
Appareil de separation et procede de fabrication d'un appareil de separation Download PDFInfo
- Publication number
- WO2003013692A1 WO2003013692A1 PCT/JP2002/007854 JP0207854W WO03013692A1 WO 2003013692 A1 WO2003013692 A1 WO 2003013692A1 JP 0207854 W JP0207854 W JP 0207854W WO 03013692 A1 WO03013692 A1 WO 03013692A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- separation
- apprattus
- appratus
- fabricating
- wells
- Prior art date
Links
- 238000000926 separation method Methods 0.000 title abstract 4
- 238000000034 method Methods 0.000 title 1
- 108091005461 Nucleic proteins Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D43/00—Separating particles from liquids, or liquids from solids, otherwise than by sedimentation or filtration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44773—Multi-stage electrophoresis, e.g. two-dimensional electrophoresis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/34—Size selective separation, e.g. size exclusion chromatography, gel filtration, permeation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/12—Specific details about manufacturing devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
- G01N30/52—Physical parameters
- G01N2030/524—Physical parameters structural properties
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49002—Electrical device making
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02751824A EP1413346A4 (en) | 2001-08-03 | 2002-08-01 | SEPARATING DEVICE AND METHOD FOR PRODUCING THE SEPARATOR |
US10/468,358 US20040108208A1 (en) | 2001-08-03 | 2002-08-01 | Separation apparatus and process for fabricating separation apparatus |
CA002436354A CA2436354C (en) | 2001-08-03 | 2002-08-01 | Separator and method of manufacturing a separator |
KR10-2004-7001670A KR20040032884A (ko) | 2001-08-03 | 2002-08-01 | 분리 장치 및 분리 장치의 제조 방법 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001237179 | 2001-08-03 | ||
JP2001-237179 | 2001-08-03 | ||
JP2002-140233 | 2002-05-15 | ||
JP2002140233 | 2002-05-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003013692A1 true WO2003013692A1 (fr) | 2003-02-20 |
Family
ID=26619976
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/007854 WO2003013692A1 (fr) | 2001-08-03 | 2002-08-01 | Appareil de separation et procede de fabrication d'un appareil de separation |
Country Status (6)
Country | Link |
---|---|
US (1) | US20040108208A1 (ja) |
EP (1) | EP1413346A4 (ja) |
KR (1) | KR20040032884A (ja) |
CN (1) | CN1494453A (ja) |
CA (1) | CA2436354C (ja) |
WO (1) | WO2003013692A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005008209A2 (ja) * | 2003-07-16 | 2005-01-27 | Toyo Boseki | 生体成分分離用デバイス、およびそれを用いた生体成分の分離方法 |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090136982A1 (en) | 2005-01-18 | 2009-05-28 | Biocept, Inc. | Cell separation using microchannel having patterned posts |
US8158410B2 (en) | 2005-01-18 | 2012-04-17 | Biocept, Inc. | Recovery of rare cells using a microchannel apparatus with patterned posts |
WO2006078470A2 (en) | 2005-01-18 | 2006-07-27 | Biocept, Inc. | Cell separation using microchannel having patterned posts |
EP1909959B1 (en) * | 2005-03-18 | 2012-01-11 | Canon Kabushiki Kaisha | Pillar structure for separating or capturing target substance |
US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
JP2008538282A (ja) * | 2005-04-05 | 2008-10-23 | セルポイント ダイアグノスティクス, インコーポレイテッド | 装置および循環腫瘍細胞および他の粒子の濃縮および変更のための方法 |
US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
US7695956B2 (en) | 2006-01-12 | 2010-04-13 | Biocept, Inc. | Device for cell separation and analysis and method of using |
WO2007101149A2 (en) * | 2006-02-27 | 2007-09-07 | Weishi Feng | Method for providing e-mail spam rejection employing user controlled and service provider controlled access lists |
KR101105710B1 (ko) * | 2008-06-09 | 2012-01-17 | 서강대학교산학협력단 | 나노-바이오플랫폼의 제조방법 |
JP2017053808A (ja) * | 2015-09-11 | 2017-03-16 | 株式会社東芝 | 半導体分析チップ及び微粒子検査方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH03134561A (ja) * | 1989-10-19 | 1991-06-07 | Yokogawa Electric Corp | カテコールアミン類の分析方法 |
JPH11108891A (ja) * | 1997-10-03 | 1999-04-23 | Shimadzu Corp | 電気泳動装置 |
JP2000249706A (ja) * | 1999-02-26 | 2000-09-14 | Hokuto Kagaku Sangyo Kk | 新規の生物学的チップ及び分析方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1183833A (en) * | 1966-08-11 | 1970-03-11 | Victor Pretorious | Improvements in Chromatographic Processes and Apparatus. |
EP0899567A1 (en) * | 1989-07-06 | 1999-03-03 | Perseptive Biosystems, Inc. | Perfusive Chromatography |
US5750015A (en) * | 1990-02-28 | 1998-05-12 | Soane Biosciences | Method and device for moving molecules by the application of a plurality of electrical fields |
US5427663A (en) * | 1993-06-08 | 1995-06-27 | British Technology Group Usa Inc. | Microlithographic array for macromolecule and cell fractionation |
WO1996020401A1 (fr) * | 1994-12-26 | 1996-07-04 | Kabushiki Kaisya Advance | Dispositif de chromatographie a canal poreux |
US6039897A (en) * | 1996-08-28 | 2000-03-21 | University Of Washington | Multiple patterned structures on a single substrate fabricated by elastomeric micro-molding techniques |
DE19815882A1 (de) * | 1998-04-08 | 1999-10-14 | Fuhr Guenther | Verfahren und Vorrichtung zur Manipulierung von Mikropartikeln in Fluidströmungen |
EP1716926A3 (en) * | 2000-04-13 | 2007-08-29 | Wako Pure Chemical Industries Ltd | Electrode for dielectrophoretic apparatus, dielectrophoretic apparatus, method for manufacturing the same, and method for separating substances using the electrode or dielectrophoretic apparatus |
US6881315B2 (en) * | 2001-08-03 | 2005-04-19 | Nec Corporation | Fractionating apparatus having colonies of pillars arranged in migration passage at interval and process for fabricating pillars |
JP2004042012A (ja) * | 2001-10-26 | 2004-02-12 | Nec Corp | 分離装置、分析システム、分離方法および分離装置の製造方法 |
-
2002
- 2002-08-01 CA CA002436354A patent/CA2436354C/en not_active Expired - Fee Related
- 2002-08-01 WO PCT/JP2002/007854 patent/WO2003013692A1/ja not_active Application Discontinuation
- 2002-08-01 EP EP02751824A patent/EP1413346A4/en not_active Withdrawn
- 2002-08-01 US US10/468,358 patent/US20040108208A1/en not_active Abandoned
- 2002-08-01 KR KR10-2004-7001670A patent/KR20040032884A/ko not_active Application Discontinuation
- 2002-08-01 CN CNA028055497A patent/CN1494453A/zh active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH03134561A (ja) * | 1989-10-19 | 1991-06-07 | Yokogawa Electric Corp | カテコールアミン類の分析方法 |
JPH11108891A (ja) * | 1997-10-03 | 1999-04-23 | Shimadzu Corp | 電気泳動装置 |
JP2000249706A (ja) * | 1999-02-26 | 2000-09-14 | Hokuto Kagaku Sangyo Kk | 新規の生物学的チップ及び分析方法 |
Non-Patent Citations (1)
Title |
---|
See also references of EP1413346A4 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005008209A2 (ja) * | 2003-07-16 | 2005-01-27 | Toyo Boseki | 生体成分分離用デバイス、およびそれを用いた生体成分の分離方法 |
WO2005008209A3 (ja) * | 2003-07-16 | 2005-03-24 | Toyo Boseki | 生体成分分離用デバイス、およびそれを用いた生体成分の分離方法 |
Also Published As
Publication number | Publication date |
---|---|
CN1494453A (zh) | 2004-05-05 |
EP1413346A1 (en) | 2004-04-28 |
EP1413346A4 (en) | 2005-05-25 |
CA2436354C (en) | 2007-04-10 |
CA2436354A1 (en) | 2003-02-20 |
KR20040032884A (ko) | 2004-04-17 |
US20040108208A1 (en) | 2004-06-10 |
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