WO2003002170A3 - Minimally invasive drug delivery catheter - Google Patents

Minimally invasive drug delivery catheter Download PDF

Info

Publication number
WO2003002170A3
WO2003002170A3 PCT/US2002/021945 US0221945W WO03002170A3 WO 2003002170 A3 WO2003002170 A3 WO 2003002170A3 US 0221945 W US0221945 W US 0221945W WO 03002170 A3 WO03002170 A3 WO 03002170A3
Authority
WO
WIPO (PCT)
Prior art keywords
catheter
implanted
time
drug delivery
minimally invasive
Prior art date
Application number
PCT/US2002/021945
Other languages
French (fr)
Other versions
WO2003002170A2 (en
Inventor
Edward M Gillis
Original Assignee
Durect Corp
Edward M Gillis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Durect Corp, Edward M Gillis filed Critical Durect Corp
Priority to AU2002320423A priority Critical patent/AU2002320423A1/en
Priority to EP02749940A priority patent/EP1409040A4/en
Publication of WO2003002170A2 publication Critical patent/WO2003002170A2/en
Publication of WO2003002170A3 publication Critical patent/WO2003002170A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/008Strength or flexibility characteristics of the catheter tip
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/0069Tip not integral with tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M2025/0042Microcatheters, cannula or the like having outside diameters around 1 mm or less
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0693Brain, cerebrum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M25/0054Catheters; Hollow probes characterised by structural features with regions for increasing flexibility
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure

Abstract

The catheter of the invention is of a design adapted to be implanted, and fixed in place, without the use of a trocar or cannula, such that tissue damage is minimized both at the time of implantation, and later, over the period that the catheter remains implanted. In one embodiment, the catheter may be used to deliver a drug over a prolonged period of time, to a precise location, for instance to treat an inoperative tumor of the brain stem. In another embodiment, the catheter of the invention may be implanted, and maintained in place and used to deliver repeated doses of a drug to the same target over time without the necessity of repeatedly re-implanting a needle through tissue to access the target site.
PCT/US2002/021945 2001-06-27 2002-06-27 Minimally invasive drug delivery catheter WO2003002170A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2002320423A AU2002320423A1 (en) 2001-06-27 2002-06-27 Minimally invasive drug delivery catheter
EP02749940A EP1409040A4 (en) 2001-06-27 2002-06-27 Minimally invasive drug delivery catheter

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30163101P 2001-06-27 2001-06-27
US60/301,631 2001-06-27

Publications (2)

Publication Number Publication Date
WO2003002170A2 WO2003002170A2 (en) 2003-01-09
WO2003002170A3 true WO2003002170A3 (en) 2003-03-20

Family

ID=23164190

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/021945 WO2003002170A2 (en) 2001-06-27 2002-06-27 Minimally invasive drug delivery catheter

Country Status (3)

Country Link
EP (1) EP1409040A4 (en)
AU (1) AU2002320423A1 (en)
WO (1) WO2003002170A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9162024B2 (en) 2008-05-08 2015-10-20 Minipumps, Llc Drug-delivery pumps and methods of manufacture
US9308124B2 (en) 2007-12-20 2016-04-12 University Of Southern California Apparatus and methods for delivering therapeutic agents

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8946151B2 (en) 2003-02-24 2015-02-03 Northern Bristol N.H.S. Trust Frenchay Hospital Method of treating Parkinson's disease in humans by convection-enhanced infusion of glial cell-line derived neurotrophic factor to the putamen
US8246569B1 (en) 2004-08-17 2012-08-21 California Institute Of Technology Implantable intraocular pressure drain
WO2007106557A2 (en) 2006-03-14 2007-09-20 University Of Southern California Mems device for delivery of therapeutic agents
US7766394B2 (en) * 2006-10-30 2010-08-03 Medtronic, Inc. Breakaway connectors and systems
GB0802634D0 (en) * 2008-02-13 2008-03-19 Renishaw Plc Catheter
US8480626B2 (en) 2007-11-30 2013-07-09 Medtronic, Inc. Infusion catheter assembly with reduced backflow
US20090192493A1 (en) 2008-01-03 2009-07-30 University Of Southern California Implantable drug-delivery devices, and apparatus and methods for refilling the devices
US9849238B2 (en) 2008-05-08 2017-12-26 Minipumps, Llc Drug-delivery pump with intelligent control
CA2723723C (en) 2008-05-08 2019-06-25 Replenish Pumps, Llc Implantable drug-delivery devices, and apparatus and methods for filling the devices
CA2723724C (en) 2008-05-08 2017-03-14 Replenish Pumps, Llc Implantable pumps and cannulas therefor
KR101697388B1 (en) 2009-08-18 2017-01-17 미니펌프스, 엘엘씨 Electrolytic drug-delivery pump with adaptive control
US10286146B2 (en) 2011-03-14 2019-05-14 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9603997B2 (en) 2011-03-14 2017-03-28 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9919099B2 (en) 2011-03-14 2018-03-20 Minipumps, Llc Implantable drug pumps and refill devices therefor

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5099845A (en) * 1989-05-24 1992-03-31 Micronix Pty Ltd. Medical instrument location means
US5380307A (en) * 1992-09-30 1995-01-10 Target Therapeutics, Inc. Catheter with atraumatic drug delivery tip
US5620479A (en) * 1992-11-13 1997-04-15 The Regents Of The University Of California Method and apparatus for thermal therapy of tumors
US5997524A (en) * 1997-07-18 1999-12-07 Vasca, Inc. Catheter assembly for percutaneous access to subcutaneous port

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE502055C2 (en) * 1990-05-23 1995-07-31 Atos Medical Ab Device for applying a drainage duct
US5873864A (en) * 1995-12-18 1999-02-23 Luther Medical Products, Inc. Catheter with beveled needle tip
US5913848A (en) * 1996-06-06 1999-06-22 Luther Medical Products, Inc. Hard tip over-the-needle catheter and method of manufacturing the same
US6500157B2 (en) * 1998-09-03 2002-12-31 Ronald B. Luther Intravenous infusion needle with soft body

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5099845A (en) * 1989-05-24 1992-03-31 Micronix Pty Ltd. Medical instrument location means
US5380307A (en) * 1992-09-30 1995-01-10 Target Therapeutics, Inc. Catheter with atraumatic drug delivery tip
US5620479A (en) * 1992-11-13 1997-04-15 The Regents Of The University Of California Method and apparatus for thermal therapy of tumors
US5997524A (en) * 1997-07-18 1999-12-07 Vasca, Inc. Catheter assembly for percutaneous access to subcutaneous port

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1409040A4 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9308124B2 (en) 2007-12-20 2016-04-12 University Of Southern California Apparatus and methods for delivering therapeutic agents
US9162024B2 (en) 2008-05-08 2015-10-20 Minipumps, Llc Drug-delivery pumps and methods of manufacture

Also Published As

Publication number Publication date
EP1409040A2 (en) 2004-04-21
WO2003002170A2 (en) 2003-01-09
AU2002320423A1 (en) 2003-03-03
EP1409040A4 (en) 2009-08-12

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