WO2002096445A3 - Food compositions for reducing insulin resistance - Google Patents

Food compositions for reducing insulin resistance Download PDF

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Publication number
WO2002096445A3
WO2002096445A3 PCT/EP2002/005463 EP0205463W WO02096445A3 WO 2002096445 A3 WO2002096445 A3 WO 2002096445A3 EP 0205463 W EP0205463 W EP 0205463W WO 02096445 A3 WO02096445 A3 WO 02096445A3
Authority
WO
WIPO (PCT)
Prior art keywords
insulin resistance
food compositions
reducing insulin
reducing
molecules
Prior art date
Application number
PCT/EP2002/005463
Other languages
French (fr)
Other versions
WO2002096445A2 (en
Inventor
John Anthony Bosley
Anna Louise Brown
Julia Sarah Rogers
Original Assignee
Unilever Plc
Unilever Nv
Lever Hindustan Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Plc, Unilever Nv, Lever Hindustan Ltd filed Critical Unilever Plc
Priority to AU2002344160A priority Critical patent/AU2002344160A1/en
Priority to EP02743046A priority patent/EP1390051A2/en
Publication of WO2002096445A2 publication Critical patent/WO2002096445A2/en
Publication of WO2002096445A3 publication Critical patent/WO2002096445A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Informatics (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to molecules derived from guggulipid extract which are capable of reducing insulin resistance in humans. The invention further relates food compositions and medicaments comprising such molecules which can be used to treat and/or prevent insulin resistance and the symptoms thereof.
PCT/EP2002/005463 2001-05-29 2002-05-16 Food compositions for reducing insulin resistance WO2002096445A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2002344160A AU2002344160A1 (en) 2001-05-29 2002-05-16 Food compositions for reducing insulin resistance
EP02743046A EP1390051A2 (en) 2001-05-29 2002-05-16 Food compositions for reducing insulin resistance

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01304692 2001-05-29
EP01304692.5 2001-05-29

Publications (2)

Publication Number Publication Date
WO2002096445A2 WO2002096445A2 (en) 2002-12-05
WO2002096445A3 true WO2002096445A3 (en) 2003-11-06

Family

ID=8181990

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/005463 WO2002096445A2 (en) 2001-05-29 2002-05-16 Food compositions for reducing insulin resistance

Country Status (4)

Country Link
US (1) US6737442B2 (en)
EP (1) EP1390051A2 (en)
AU (1) AU2002344160A1 (en)
WO (1) WO2002096445A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060019907A1 (en) * 2004-07-12 2006-01-26 Research Development Foundation Guggulsterone: an inhibitor of nuclear factor - kappaB and IkappaBalpha kinase activation and uses thereof

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0833464A (en) * 1994-07-22 1996-02-06 Seikosha:Kk Solid food for lean body
US5612039A (en) * 1994-03-14 1997-03-18 Nini E. Policappelli Dietary supplement
WO1998030199A1 (en) * 1997-01-10 1998-07-16 Unilever Plc Antisebum and antioxidant compositions
US5972341A (en) * 1995-09-13 1999-10-26 Parfums Christian Dior Products extracted from a plant of the genus Commiphora, particularly the Commiphora mukul plant, extracts containing same and applications thereof, for example in cosmetics
EP0997149A1 (en) * 1998-10-27 2000-05-03 Prolab Nutrition, Inc. Compositions comprising guggul extract and phosphate salts
WO2001005356A2 (en) * 1999-07-20 2001-01-25 Natrol, Inc. Weight control product comprising a synergistic mixture of guggul extract, phosphate salt and metabolic stimulant
EP1238590A1 (en) * 2001-03-09 2002-09-11 Unilever N.V. Fat based food product

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612039A (en) * 1994-03-14 1997-03-18 Nini E. Policappelli Dietary supplement
JPH0833464A (en) * 1994-07-22 1996-02-06 Seikosha:Kk Solid food for lean body
US5972341A (en) * 1995-09-13 1999-10-26 Parfums Christian Dior Products extracted from a plant of the genus Commiphora, particularly the Commiphora mukul plant, extracts containing same and applications thereof, for example in cosmetics
WO1998030199A1 (en) * 1997-01-10 1998-07-16 Unilever Plc Antisebum and antioxidant compositions
EP0997149A1 (en) * 1998-10-27 2000-05-03 Prolab Nutrition, Inc. Compositions comprising guggul extract and phosphate salts
WO2001005356A2 (en) * 1999-07-20 2001-01-25 Natrol, Inc. Weight control product comprising a synergistic mixture of guggul extract, phosphate salt and metabolic stimulant
EP1238590A1 (en) * 2001-03-09 2002-09-11 Unilever N.V. Fat based food product

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 13 August 1999 (1999-08-13), PANDA SUNANDA ET AL: "Gugulu (Commiphora mukul) induces triiodothyronine production: Possible involvement of lipid peroxidation.", XP002181992, Database accession no. PREV199900432908 *
F.M. AL-AWADI: "Studies on the activity of individual plants on an antidiabetic plant mixture", ACTA DIABETOLOGICA LATINA, vol. 24, no. 1, 1987, MILAN, IT, pages 37 - 41, XP008011130, ISSN: 0001-5563 *
LIFE SCIENCES, vol. 65, no. 12, 13 August 1999 (1999-08-13), pages 137 - 141, ISSN: 0024-3205 *
PATENT ABSTRACTS OF JAPAN vol. 1996, no. 06 28 June 1996 (1996-06-28) *
SINGH RB ET AL: "Hypolipidemic and antioxidant effects of Commiphora mukul as an adjunct to dietary therapy in patients with hypercholesterolemia", CARDIOVASCULAR DRUGS AND THERAPY, KLUWER ACADEMIC PUBLISHERS, BOSTON, US, vol. 8, no. 4, August 1994 (1994-08-01), pages 659 - 664, XP002118413, ISSN: 0920-3206 *
SUBRAMANIAM A ET AL: "GUGGUL LIPID REDUCES INSULIN RESISTANCE AND BODY WEIGHT GAIN IN C57BI/6 LEP/LEP MICE", INTERNATIONAL JOURNAL OF OBESITY, NEWMAN PUBLISHING, LONDON, GB, vol. 25, no. SUPPL 2, 2001, pages S24, XP001031213, ISSN: 0307-0565 *
UBILLAS R P ET AL: "ANTIHYPERGLYCEMIC FURANOSESQUITERPENES FROM COMMIPHORA MYRRHA", PLANTA MEDICA, THIEME, STUTTGART, DE, vol. 8, no. 65, December 1999 (1999-12-01), pages 778 - 779, XP008003375, ISSN: 0032-0943 *

Also Published As

Publication number Publication date
US20030171398A1 (en) 2003-09-11
AU2002344160A1 (en) 2002-12-09
US6737442B2 (en) 2004-05-18
EP1390051A2 (en) 2004-02-25
WO2002096445A2 (en) 2002-12-05

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