WO2002062402A1 - Antimicrobial contact lenses containing activated silver and methods for their production - Google Patents
Antimicrobial contact lenses containing activated silver and methods for their production Download PDFInfo
- Publication number
- WO2002062402A1 WO2002062402A1 PCT/US2001/050582 US0150582W WO02062402A1 WO 2002062402 A1 WO2002062402 A1 WO 2002062402A1 US 0150582 W US0150582 W US 0150582W WO 02062402 A1 WO02062402 A1 WO 02062402A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- lens
- lenses
- silver
- weight percent
- activated silver
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 34
- 230000000845 anti-microbial effect Effects 0.000 title claims abstract description 16
- 238000004519 manufacturing process Methods 0.000 title abstract description 7
- 229910052709 silver Inorganic materials 0.000 claims description 28
- 239000004332 silver Substances 0.000 claims description 28
- 239000007800 oxidant agent Substances 0.000 claims description 17
- 239000005708 Sodium hypochlorite Substances 0.000 claims description 15
- SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 claims description 15
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 14
- 239000000017 hydrogel Substances 0.000 claims description 9
- 238000006243 chemical reaction Methods 0.000 claims description 8
- 229920001296 polysiloxane Polymers 0.000 claims description 7
- 230000002411 adverse Effects 0.000 claims description 6
- 230000000813 microbial effect Effects 0.000 claims description 6
- NLAIHECABDOZBR-UHFFFAOYSA-M sodium 2,2-bis(2-methylprop-2-enoyloxymethyl)butyl 2-methylprop-2-enoate 2-hydroxyethyl 2-methylprop-2-enoate 2-methylprop-2-enoate Chemical compound [Na+].CC(=C)C([O-])=O.CC(=C)C(=O)OCCO.CCC(COC(=O)C(C)=C)(COC(=O)C(C)=C)COC(=O)C(C)=C NLAIHECABDOZBR-UHFFFAOYSA-M 0.000 claims description 6
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims description 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 3
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims description 3
- 229910052794 bromium Inorganic materials 0.000 claims description 3
- 239000000460 chlorine Substances 0.000 claims description 3
- 229910052801 chlorine Inorganic materials 0.000 claims description 3
- KRVSOGSZCMJSLX-UHFFFAOYSA-L chromic acid Substances O[Cr](O)(=O)=O KRVSOGSZCMJSLX-UHFFFAOYSA-L 0.000 claims description 3
- AWJWCTOOIBYHON-UHFFFAOYSA-N furo[3,4-b]pyrazine-5,7-dione Chemical compound C1=CN=C2C(=O)OC(=O)C2=N1 AWJWCTOOIBYHON-UHFFFAOYSA-N 0.000 claims description 3
- 150000004965 peroxy acids Chemical class 0.000 claims description 3
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 2
- 229920001616 Polymacon Polymers 0.000 claims description 2
- 239000011630 iodine Substances 0.000 claims description 2
- 229910052740 iodine Inorganic materials 0.000 claims description 2
- 239000012286 potassium permanganate Substances 0.000 claims description 2
- 238000003860 storage Methods 0.000 abstract description 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical class [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 28
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- 239000000203 mixture Substances 0.000 description 25
- 239000000243 solution Substances 0.000 description 19
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- 230000000844 anti-bacterial effect Effects 0.000 description 6
- 239000003618 borate buffered saline Substances 0.000 description 6
- 230000005764 inhibitory process Effects 0.000 description 6
- 229920000642 polymer Polymers 0.000 description 6
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 5
- 239000007983 Tris buffer Substances 0.000 description 5
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- 230000001580 bacterial effect Effects 0.000 description 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
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- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 102100035526 B melanoma antigen 1 Human genes 0.000 description 2
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- 101000874316 Homo sapiens B melanoma antigen 1 Proteins 0.000 description 2
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 2
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- 239000004793 Polystyrene Substances 0.000 description 2
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- JNOGVQJEBGEKMG-UHFFFAOYSA-N (1-methoxy-2-methylprop-1-enoxy)-trimethylsilane Chemical compound COC(=C(C)C)O[Si](C)(C)C JNOGVQJEBGEKMG-UHFFFAOYSA-N 0.000 description 1
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- DBCAQXHNJOFNGC-UHFFFAOYSA-N 4-bromo-1,1,1-trifluorobutane Chemical compound FC(F)(F)CCCBr DBCAQXHNJOFNGC-UHFFFAOYSA-N 0.000 description 1
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- 241000588724 Escherichia coli Species 0.000 description 1
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- 241000593989 Scardinius erythrophthalmus Species 0.000 description 1
- 241000607720 Serratia Species 0.000 description 1
- UKLDJPRMSDWDSL-UHFFFAOYSA-L [dibutyl(dodecanoyloxy)stannyl] dodecanoate Chemical compound CCCCCCCCCCCC(=O)O[Sn](CCCC)(CCCC)OC(=O)CCCCCCCCCCC UKLDJPRMSDWDSL-UHFFFAOYSA-L 0.000 description 1
- 229960000583 acetic acid Drugs 0.000 description 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
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- 230000015572 biosynthetic process Effects 0.000 description 1
- MQDJYUACMFCOFT-UHFFFAOYSA-N bis[2-(1-hydroxycyclohexyl)phenyl]methanone Chemical compound C=1C=CC=C(C(=O)C=2C(=CC=CC=2)C2(O)CCCCC2)C=1C1(O)CCCCC1 MQDJYUACMFCOFT-UHFFFAOYSA-N 0.000 description 1
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- 239000012975 dibutyltin dilaurate Substances 0.000 description 1
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- SUPCQIBBMFXVTL-UHFFFAOYSA-N ethyl 2-methylprop-2-enoate Chemical compound CCOC(=O)C(C)=C SUPCQIBBMFXVTL-UHFFFAOYSA-N 0.000 description 1
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- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
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Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
-
- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/088—Heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
Abstract
Description
Claims
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE60117863T DE60117863T2 (en) | 2000-12-21 | 2001-12-21 | ACTIVATED SILVER ANTIMICROBIAL CONTACT LENS CONTAINING AND METHOD FOR THE PRODUCTION THEREOF |
JP2002562407A JP2004526187A (en) | 2000-12-21 | 2001-12-21 | Antibacterial contact lens containing activated silver and method for producing the same |
CA002432796A CA2432796A1 (en) | 2000-12-21 | 2001-12-21 | Antimicrobial contact lenses containing activated silver and methods for their production |
BR0116479-1A BR0116479A (en) | 2000-12-21 | 2001-12-21 | Antimicrobial contact lenses containing activated silver and processes for their production |
KR10-2003-7008463A KR20030063460A (en) | 2000-12-21 | 2001-12-21 | Antimicrobial contact lenses containing activated silver and method for their production |
EP01994478A EP1355681B1 (en) | 2000-12-21 | 2001-12-21 | Antimicrobial contact lenses containing activated silver and methods for their production |
HK03108941A HK1056516A1 (en) | 2000-12-21 | 2003-12-09 | Antimicrobial contact lenses containing activated silver and methods their production |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25731700P | 2000-12-21 | 2000-12-21 | |
US60/257,317 | 2000-12-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2002062402A1 true WO2002062402A1 (en) | 2002-08-15 |
Family
ID=22975788
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/050582 WO2002062402A1 (en) | 2000-12-21 | 2001-12-21 | Antimicrobial contact lenses containing activated silver and methods for their production |
Country Status (11)
Country | Link |
---|---|
US (1) | US20020197299A1 (en) |
EP (1) | EP1355681B1 (en) |
JP (1) | JP2004526187A (en) |
KR (1) | KR20030063460A (en) |
CN (1) | CN100363061C (en) |
BR (1) | BR0116479A (en) |
CA (1) | CA2432796A1 (en) |
DE (1) | DE60117863T2 (en) |
HK (1) | HK1056516A1 (en) |
TW (1) | TWI229209B (en) |
WO (1) | WO2002062402A1 (en) |
Cited By (14)
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WO2005014074A1 (en) * | 2003-07-16 | 2005-02-17 | Novartis Ag | Antimicrobial medical devices |
WO2005033751A1 (en) * | 2003-09-30 | 2005-04-14 | Johnson & Johnson Vision Care, Inc. | Methods of preparing ophthalmic devices |
WO2005058253A1 (en) * | 2003-12-17 | 2005-06-30 | Heraeus Kulzer Gmbh | Antimicrobial nano silver additive for polymerizable dental materials |
WO2005073289A1 (en) * | 2004-01-28 | 2005-08-11 | Qinetiq Nanomaterials Limited | Method of manufacture of polymer composites |
WO2005088351A2 (en) * | 2004-03-17 | 2005-09-22 | Thorkild Andersen | Contact lens, container and insert for avoiding infection of the eye |
JP2005535478A (en) * | 2002-08-16 | 2005-11-24 | ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド | Mold for contact lens manufacturing |
JP2006076295A (en) * | 2004-08-26 | 2006-03-23 | Johnson & Johnson Vision Care Inc | Mold form for manufacturing lens for eye |
JP2006511302A (en) * | 2002-12-23 | 2006-04-06 | ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド | Contact lens package with additives |
WO2008094876A1 (en) | 2007-01-31 | 2008-08-07 | Novartis Ag | Antimicrobial medical devices including silver nanoparticles |
US7960465B2 (en) | 2006-06-30 | 2011-06-14 | Johnson & Johnson Vision Care, Inc. | Antimicrobial lenses, processes to prepare them and methods of their use |
EP2384773A1 (en) | 2002-11-22 | 2011-11-09 | Johnson & Johnson Vision Care, Inc. | Antimicrobial lenses, processes to prepare them and methods of their use |
US8501833B2 (en) | 2005-12-14 | 2013-08-06 | Novartis Ag | Method for preparing silicone hydrogels |
US9358317B2 (en) | 2006-10-31 | 2016-06-07 | Johnson & Johnson Vision Care, Inc. | Acidic processes to prepare antimicrobial contact lenses |
EP3248621A1 (en) | 2007-10-08 | 2017-11-29 | Johnson & Johnson Vision Care, Inc. | Methods for forming stabilized metal salt particles |
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US20050008676A1 (en) * | 2002-12-19 | 2005-01-13 | Yongxing Qiu | Medical devices having antimicrobial coatings thereon |
US9297928B2 (en) | 2004-11-22 | 2016-03-29 | Johnson & Johnson Vision Care, Inc. | Ophthalmic compositions comprising polyether substituted polymers |
US7319133B2 (en) * | 2005-08-09 | 2008-01-15 | Coopervision, Inc. | Contact lens extraction/hydration systems and methods of reprocessing fluids used therein |
EP1913029A1 (en) * | 2005-08-10 | 2008-04-23 | Novartis AG | Silicone hydrogels |
DE102005053295C5 (en) * | 2005-11-08 | 2013-03-07 | Spiegelberg GmbH & Co. KG | Process for producing a sterile-packed, metal-containing plastic body having an antimicrobial surface |
US20080241225A1 (en) * | 2007-03-31 | 2008-10-02 | Hill Gregory A | Basic processes to prepare antimicrobial contact lenses |
DE102007025452A1 (en) | 2007-05-31 | 2008-12-04 | Ernst-Moritz-Arndt-Universität Greifswald | Surface coating method for precipitating layers onto e.g., medical appliances, involves pre-treating surface with plasma process before applying micro- or nano-particles and then fixing |
CN102445716A (en) * | 2010-10-12 | 2012-05-09 | 鸿富锦精密工业(深圳)有限公司 | Lens and manufacturing method as well as manufacturing equipment of lens |
CN111032060A (en) | 2017-06-28 | 2020-04-17 | 科利迪恩公司 | Compositions, methods and uses for cleaning, disinfecting and/or sterilizing |
CN111801122B (en) | 2018-01-14 | 2023-06-02 | 科利迪恩公司 | Compositions, kits, methods and uses for cleaning, sanitizing, disinfecting and/or treating |
CN112695521B (en) * | 2020-12-25 | 2023-04-28 | 安徽工程大学 | Halamine modified antibacterial mesoporous material and synthesis method thereof |
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WO1998018330A1 (en) * | 1996-10-28 | 1998-05-07 | Surfacine Development Company, Llc | Contact-killing non-leaching antimicrobial materials |
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EP1050314A1 (en) * | 1999-05-07 | 2000-11-08 | Healthshield Technologies L.L.C. | Antimicrobial contact lens |
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JPH0476518A (en) * | 1990-07-19 | 1992-03-11 | Sangi Co Ltd | Antibacterial contact lens |
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-
2001
- 2001-12-20 US US10/027,740 patent/US20020197299A1/en not_active Abandoned
- 2001-12-21 JP JP2002562407A patent/JP2004526187A/en active Pending
- 2001-12-21 CN CNB01822766XA patent/CN100363061C/en not_active Expired - Fee Related
- 2001-12-21 WO PCT/US2001/050582 patent/WO2002062402A1/en active IP Right Grant
- 2001-12-21 TW TW090131769A patent/TWI229209B/en not_active IP Right Cessation
- 2001-12-21 DE DE60117863T patent/DE60117863T2/en not_active Expired - Lifetime
- 2001-12-21 KR KR10-2003-7008463A patent/KR20030063460A/en not_active Application Discontinuation
- 2001-12-21 CA CA002432796A patent/CA2432796A1/en not_active Abandoned
- 2001-12-21 BR BR0116479-1A patent/BR0116479A/en not_active Application Discontinuation
- 2001-12-21 EP EP01994478A patent/EP1355681B1/en not_active Expired - Lifetime
-
2003
- 2003-12-09 HK HK03108941A patent/HK1056516A1/en not_active IP Right Cessation
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US5312586A (en) * | 1991-06-21 | 1994-05-17 | Stockel Richard F | Process for sterilizing a contact lens |
US5515117A (en) * | 1993-05-06 | 1996-05-07 | Allergan, Inc. | Antimicrobial lenses and lens care systems |
WO1998018330A1 (en) * | 1996-10-28 | 1998-05-07 | Surfacine Development Company, Llc | Contact-killing non-leaching antimicrobial materials |
WO2000038552A1 (en) * | 1998-12-31 | 2000-07-06 | Healthshield Technologies Llc | Antimicrobial contact lens case |
EP1050314A1 (en) * | 1999-05-07 | 2000-11-08 | Healthshield Technologies L.L.C. | Antimicrobial contact lens |
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Title |
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NISSEN S ET AL: "[Antimicrobial efficacy of a silver layer on hydrogel lenses] Citation]", DER OPHTHALMOLOGE: ZEITSCHRIFT DER DEUTSCHEN OPHTHALMOLOGISCHEN GESELLSCHAFT. GERMANY SEP 2000, vol. 97, no. 9, September 2000 (2000-09-01), pages 640 - 643, XP002204043, ISSN: 0941-293X * |
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JP2005535478A (en) * | 2002-08-16 | 2005-11-24 | ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド | Mold for contact lens manufacturing |
JP4708023B2 (en) * | 2002-08-16 | 2011-06-22 | ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド | Mold for contact lens manufacturing |
US8292256B2 (en) | 2002-08-16 | 2012-10-23 | Johnson & Johnson Vision Care, Inc. | Molds for producing contact lenses |
EP2384773A1 (en) | 2002-11-22 | 2011-11-09 | Johnson & Johnson Vision Care, Inc. | Antimicrobial lenses, processes to prepare them and methods of their use |
EP2384772A2 (en) | 2002-11-22 | 2011-11-09 | Johnson & Johnson Vision Care, Inc. | Antimicrobial lenses, processes to prepare them and methods of their use |
JP2006511302A (en) * | 2002-12-23 | 2006-04-06 | ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド | Contact lens package with additives |
JP4776926B2 (en) * | 2002-12-23 | 2011-09-21 | ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド | Contact lens package with additives |
WO2005014074A1 (en) * | 2003-07-16 | 2005-02-17 | Novartis Ag | Antimicrobial medical devices |
US8425926B2 (en) | 2003-07-16 | 2013-04-23 | Yongxing Qiu | Antimicrobial medical devices |
AU2004262891B2 (en) * | 2003-07-16 | 2007-04-05 | Novartis Ag | Antimicrobial medical devices |
CN100374169C (en) * | 2003-07-16 | 2008-03-12 | 诺瓦提斯公司 | Antimicrobial medical devices |
JP2009500645A (en) * | 2003-07-16 | 2009-01-08 | ノバルティス アクチエンゲゼルシャフト | Antibacterial medical device |
WO2005033751A1 (en) * | 2003-09-30 | 2005-04-14 | Johnson & Johnson Vision Care, Inc. | Methods of preparing ophthalmic devices |
WO2005058253A1 (en) * | 2003-12-17 | 2005-06-30 | Heraeus Kulzer Gmbh | Antimicrobial nano silver additive for polymerizable dental materials |
GB2425126A (en) * | 2004-01-28 | 2006-10-18 | Qinetiq Nanomaterials Ltd | Method of manufacture of polymer composites |
WO2005073289A1 (en) * | 2004-01-28 | 2005-08-11 | Qinetiq Nanomaterials Limited | Method of manufacture of polymer composites |
WO2005088351A3 (en) * | 2004-03-17 | 2006-03-16 | Thorkild Andersen | Contact lens, container and insert for avoiding infection of the eye |
WO2005088351A2 (en) * | 2004-03-17 | 2005-09-22 | Thorkild Andersen | Contact lens, container and insert for avoiding infection of the eye |
JP2006076295A (en) * | 2004-08-26 | 2006-03-23 | Johnson & Johnson Vision Care Inc | Mold form for manufacturing lens for eye |
US8501833B2 (en) | 2005-12-14 | 2013-08-06 | Novartis Ag | Method for preparing silicone hydrogels |
US7960465B2 (en) | 2006-06-30 | 2011-06-14 | Johnson & Johnson Vision Care, Inc. | Antimicrobial lenses, processes to prepare them and methods of their use |
US9358317B2 (en) | 2006-10-31 | 2016-06-07 | Johnson & Johnson Vision Care, Inc. | Acidic processes to prepare antimicrobial contact lenses |
WO2008094876A1 (en) | 2007-01-31 | 2008-08-07 | Novartis Ag | Antimicrobial medical devices including silver nanoparticles |
EP3248621A1 (en) | 2007-10-08 | 2017-11-29 | Johnson & Johnson Vision Care, Inc. | Methods for forming stabilized metal salt particles |
US9872501B2 (en) | 2007-10-08 | 2018-01-23 | Johnson & Johnson Vision Care, Inc. | Methods for forming stabilized metal salt particles |
Also Published As
Publication number | Publication date |
---|---|
CA2432796A1 (en) | 2002-08-15 |
DE60117863T2 (en) | 2006-11-16 |
HK1056516A1 (en) | 2004-02-20 |
US20020197299A1 (en) | 2002-12-26 |
EP1355681B1 (en) | 2006-03-08 |
TWI229209B (en) | 2005-03-11 |
CN1630536A (en) | 2005-06-22 |
DE60117863D1 (en) | 2006-05-04 |
JP2004526187A (en) | 2004-08-26 |
BR0116479A (en) | 2004-01-13 |
CN100363061C (en) | 2008-01-23 |
EP1355681A1 (en) | 2003-10-29 |
KR20030063460A (en) | 2003-07-28 |
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