WO2002061083A1 - Nouvelle proteine de recepteur couple aux proteines g et son adn - Google Patents

Nouvelle proteine de recepteur couple aux proteines g et son adn Download PDF

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Publication number
WO2002061083A1
WO2002061083A1 PCT/JP2002/000635 JP0200635W WO02061083A1 WO 2002061083 A1 WO2002061083 A1 WO 2002061083A1 JP 0200635 W JP0200635 W JP 0200635W WO 02061083 A1 WO02061083 A1 WO 02061083A1
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WO
WIPO (PCT)
Prior art keywords
protein
same
novel
coupled receptor
dna
Prior art date
Application number
PCT/JP2002/000635
Other languages
English (en)
Japanese (ja)
Inventor
Keiji Iwamoto
Shuji Sato
Yasushi Shintani
Original Assignee
Takeda Chemical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries, Ltd. filed Critical Takeda Chemical Industries, Ltd.
Publication of WO2002061083A1 publication Critical patent/WO2002061083A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne une nouvelle protéine de récepteur couplé aux protéines G contenant une séquence d'acides aminés identique ou sensiblement identique à la séquence d'acides aminés représentée par SEQ ID NO:1, un polynucléotide codant pour celle-ci, etc. Cette protéine d'origine humaine et l'ADN codant pour celle-ci peuvent être utilisés (1) pour déterminer un ligand associé à ladite protéine, (2) comme agents prophylactiques et/ou thérapeutiques destinés à des maladies en rapport avec l'hypofonction de cette protéine, (3) dans le criblage d'un composé (agoniste, antagoniste, etc.) capable de modifier les propriétés de liaison de cette protéine à un ligand, etc.
PCT/JP2002/000635 2001-01-30 2002-01-29 Nouvelle proteine de recepteur couple aux proteines g et son adn WO2002061083A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2001-21581 2001-01-30
JP2001021581 2001-01-30
JP2001102485 2001-03-30
JP2001-102485 2001-03-30

Publications (1)

Publication Number Publication Date
WO2002061083A1 true WO2002061083A1 (fr) 2002-08-08

Family

ID=26608518

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/000635 WO2002061083A1 (fr) 2001-01-30 2002-01-29 Nouvelle proteine de recepteur couple aux proteines g et son adn

Country Status (1)

Country Link
WO (1) WO2002061083A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003051925A1 (fr) * 2001-12-19 2003-06-26 Bayer Healthcare Ag Gpcr de type secretine humaine (latrophiline)
EP1383790A4 (fr) * 2001-03-28 2006-08-09 Applera Corp Recepteurs couples a des proteines g (gpcr) isolees, molecules d'acides nucleiques codant pour la proteine gpcr humaine et leurs utilisations

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000021999A1 (fr) * 1998-10-09 2000-04-20 Chugai Research Institute For Molecular Medicine, Inc. Nouveaux recepteurs couples a la proteine g
WO2000034473A2 (fr) * 1998-12-10 2000-06-15 Zymogenetics, Inc. Domaine transmembranaire 7 zsig56

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000021999A1 (fr) * 1998-10-09 2000-04-20 Chugai Research Institute For Molecular Medicine, Inc. Nouveaux recepteurs couples a la proteine g
WO2000034473A2 (fr) * 1998-12-10 2000-06-15 Zymogenetics, Inc. Domaine transmembranaire 7 zsig56

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1383790A4 (fr) * 2001-03-28 2006-08-09 Applera Corp Recepteurs couples a des proteines g (gpcr) isolees, molecules d'acides nucleiques codant pour la proteine gpcr humaine et leurs utilisations
WO2003051925A1 (fr) * 2001-12-19 2003-06-26 Bayer Healthcare Ag Gpcr de type secretine humaine (latrophiline)

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