WO2002055556A2 - Regulation de la proteine a canal de potassium a porte de tension humaine kv2.2 - Google Patents

Regulation de la proteine a canal de potassium a porte de tension humaine kv2.2 Download PDF

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Publication number
WO2002055556A2
WO2002055556A2 PCT/EP2002/000128 EP0200128W WO02055556A2 WO 2002055556 A2 WO2002055556 A2 WO 2002055556A2 EP 0200128 W EP0200128 W EP 0200128W WO 02055556 A2 WO02055556 A2 WO 02055556A2
Authority
WO
WIPO (PCT)
Prior art keywords
potassium channel
polypeptide
channel protein
voltage gated
gated potassium
Prior art date
Application number
PCT/EP2002/000128
Other languages
English (en)
Other versions
WO2002055556A3 (fr
Inventor
Yonghong Xiao
Original Assignee
Bayer Ag
Yonghong Xiao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Yonghong Xiao filed Critical Bayer Ag
Publication of WO2002055556A2 publication Critical patent/WO2002055556A2/fr
Publication of WO2002055556A3 publication Critical patent/WO2002055556A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne des réactifs régulant la protéine de canal potassium à portail de tension humaine KV2.2 et des réactifs se liant à des produits génétiques de la protéine de canal potassium à porte de tension humaine KV2.2 qui peuvent jouer un rôle dans la prévention, l'amélioration ou la correction de dysfonctionnements ou de maladies, comprenant de manière non exhaustive, le diabète, le cancer, des troubles du système nerveux central ou périphérique et des troubles cardio-vasculaires.
PCT/EP2002/000128 2001-01-12 2002-01-09 Regulation de la proteine a canal de potassium a porte de tension humaine kv2.2 WO2002055556A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26088001P 2001-01-12 2001-01-12
US60/260,880 2001-01-12
US33122901P 2001-11-13 2001-11-13
US60/331,229 2001-11-13

Publications (2)

Publication Number Publication Date
WO2002055556A2 true WO2002055556A2 (fr) 2002-07-18
WO2002055556A3 WO2002055556A3 (fr) 2003-02-13

Family

ID=26948240

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/000128 WO2002055556A2 (fr) 2001-01-12 2002-01-09 Regulation de la proteine a canal de potassium a porte de tension humaine kv2.2

Country Status (1)

Country Link
WO (1) WO2002055556A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006092660A1 (fr) * 2004-11-22 2006-09-08 Integragen Gene humain de susceptibilite a l'obesite codant pour des canaux ioniques au potassium et leurs utilisations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6727353B2 (en) * 2000-04-14 2004-04-27 Icagen, Inc. Nucleic acid encoding Kv10.1, a voltage-gated potassium channel from human brain
WO2002010389A2 (fr) * 2000-07-28 2002-02-07 Lexicon Genetics Incorporated Nouvelles proteines du canal ionique humain et polynucleotides codant ces dernieres

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006092660A1 (fr) * 2004-11-22 2006-09-08 Integragen Gene humain de susceptibilite a l'obesite codant pour des canaux ioniques au potassium et leurs utilisations

Also Published As

Publication number Publication date
WO2002055556A3 (fr) 2003-02-13

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