WO2002050106A3 - Compositions and methods involving an essential staphylococcus aureus gene and its encoded protein staau_r4 - Google Patents

Compositions and methods involving an essential staphylococcus aureus gene and its encoded protein staau_r4 Download PDF

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Publication number
WO2002050106A3
WO2002050106A3 PCT/CA2001/001847 CA0101847W WO0250106A3 WO 2002050106 A3 WO2002050106 A3 WO 2002050106A3 CA 0101847 W CA0101847 W CA 0101847W WO 0250106 A3 WO0250106 A3 WO 0250106A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
staphylococcus aureus
staau
methods involving
encoded protein
Prior art date
Application number
PCT/CA2001/001847
Other languages
French (fr)
Other versions
WO2002050106A2 (en
Inventor
Jerry Pelletier
Philippe Gros
Michael Dubow
Original Assignee
Phagetech Inc
Jerry Pelletier
Philippe Gros
Michael Dubow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phagetech Inc, Jerry Pelletier, Philippe Gros, Michael Dubow filed Critical Phagetech Inc
Priority to JP2002551999A priority Critical patent/JP2004532612A/en
Priority to AU2002224692A priority patent/AU2002224692B2/en
Priority to EP01994577A priority patent/EP1345960A2/en
Priority to AU2469202A priority patent/AU2469202A/en
Priority to CA002433308A priority patent/CA2433308A1/en
Publication of WO2002050106A2 publication Critical patent/WO2002050106A2/en
Publication of WO2002050106A3 publication Critical patent/WO2002050106A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention relates to bacterial genes and proteins that are implicated in the process of fatty acid/phospholipid biosynthesis and also to bacteriophage genes and their protein products that interact with bacterial proteins implicated in fatty acid/phospholipid biosynthesis. More particularly, the invention relates to compositions and methods involving essential Staphylococcus aureus genes and its encoded proteins STAAU_R4. In addition, the invention relates to screening assays to identify compounds which modulate the level and/or activity of STAAU_R4 and to such compounds.
PCT/CA2001/001847 2000-12-20 2001-12-19 Compositions and methods involving an essential staphylococcus aureus gene and its encoded protein staau_r4 WO2002050106A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2002551999A JP2004532612A (en) 2000-12-20 2001-12-19 Compositions and methods involving the essential Staphylococcus aureus gene and its encoded protein STAAU_R4.
AU2002224692A AU2002224692B2 (en) 2000-12-20 2001-12-19 Compositions and methods involving an essential staphylococcus aureus gene and its encoded protein STAAU_R4
EP01994577A EP1345960A2 (en) 2000-12-20 2001-12-19 Compositions and methods involving an essential staphylococcus aureus gene and its encoded protein staau-r4
AU2469202A AU2469202A (en) 2000-12-20 2001-12-19 Compositions and methods involving an essential staphylococcus aureus gene and its encoded protein staau r4
CA002433308A CA2433308A1 (en) 2000-12-20 2001-12-19 Compositions and methods involving an essential staphylococcus aureus gene and its encoded protein staau_r4

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25648900P 2000-12-20 2000-12-20
US60/256,489 2000-12-20

Publications (2)

Publication Number Publication Date
WO2002050106A2 WO2002050106A2 (en) 2002-06-27
WO2002050106A3 true WO2002050106A3 (en) 2002-12-12

Family

ID=22972412

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2001/001847 WO2002050106A2 (en) 2000-12-20 2001-12-19 Compositions and methods involving an essential staphylococcus aureus gene and its encoded protein staau_r4

Country Status (5)

Country Link
EP (1) EP1345960A2 (en)
JP (1) JP2004532612A (en)
AU (2) AU2469202A (en)
CA (1) CA2433308A1 (en)
WO (1) WO2002050106A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111798712B (en) * 2020-07-15 2021-10-29 周晓庆 3D intelligent simulation method for bacteriophage infected bacteria

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002531107A (en) * 1998-12-03 2002-09-24 フェージテック，インコーポレーテッド Development of new antimicrobial agents based on bacteriophage genomics

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 24 April 2001 (2001-04-24), KURODA, M. ET AL.: "Staphylococcus aureus subsp. aureus genomic DNA, complete genome, section 5/10", XP002215850, Database accession no. AP003133 *
MAKOTO KURODA ET AL.: "Whole genome sequencing of meticillin-resistant Staphylococcus aureus", LANCET, vol. 357, Q99UN), April 2001 (2001-04-01), pages 1225 - 1240, XP004246103 *
MORBIDONI H R ET AL: "Bacillus subtilis acyl carrier protein is encoded in a cluster of lipid biosynthesis genes", JOURNAL OF BACTERIOLOGY, WASHINGTON, DC, US, vol. 178, no. 16, August 1996 (1996-08-01), pages 4794 - 4800, XP002119514, ISSN: 0021-9193 *
See also references of EP1345960A2 *

Also Published As

Publication number Publication date
AU2002224692B2 (en) 2007-05-24
AU2469202A (en) 2002-07-01
WO2002050106A2 (en) 2002-06-27
CA2433308A1 (en) 2002-06-27
JP2004532612A (en) 2004-10-28
EP1345960A2 (en) 2003-09-24

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