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WO2002047578A1 - Implant, method for inserting a reinforcing element, and method for producing an implant - Google Patents

Implant, method for inserting a reinforcing element, and method for producing an implant

Info

Publication number
WO2002047578A1
WO2002047578A1 PCT/DE2001/004722 DE0104722W WO0247578A1 WO 2002047578 A1 WO2002047578 A1 WO 2002047578A1 DE 0104722 W DE0104722 W DE 0104722W WO 0247578 A1 WO0247578 A1 WO 0247578A1
Authority
WO
Grant status
Application
Patent type
Prior art keywords
implant
means
tissue
guide
stable
Prior art date
Application number
PCT/DE2001/004722
Other languages
German (de)
French (fr)
Inventor
Kornel Tordy
Friedhelm Limbeck
Janine Tordy
Original Assignee
Kornel Tordy
Friedhelm Limbeck
Janine Tordy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/048Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L27/00Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers
    • C08L27/02Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L27/12Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment containing fluorine atoms
    • C08L27/18Homopolymers or copolymers or tetrafluoroethene

Abstract

The aim of the invention is to provide an implant, which joins with a tissue as quickly as possible and yet is sufficiently compatible with the tissue. To this end, the invention provides an implant comprised of a tissue-compatible microporous material, which has at least one sturdy opening.

Description

Implant, method of introducing a reinforcing member and method for manufacturing an implant

The invention relates to an implant made of a tissue-compatible microporous material, a method for introducing a Verstärkungsele- mentes in an area surrounded by a sheath soft structure and a method for manufacturing an implant from a blank.

For example, nets, braided belts and pillows in particular for surgical use are known that can be implanted. The materials used in this regard usually polyamides or silicones used. but these have the disadvantage that they are not sufficiently grown because of their constellation with the tissue. This leads to incompatibilities as encapsulants to a rejection of the corresponding implant. The implants are mostly sewn to the fabric, so as not to slip. did particularly at Kissenimplan- is exacerbated by the size of these implants must be determined prior to surgery and ordered so unfavorably further surgery is necessary if it is found during surgery that the intended implant is not the required size equivalent. As a surgical procedure always rationsrisiken OPE contains within itself, in particular, a second surgery a major drawback.

On the other hand implants made of a tissue-compatible microporous material of the prior art are well known and are described for example in different variations for the cosmetic surgery or trauma surgery, z. B. as tissue replacement offered. Here, in particular, expanded polytetrafluoroethylene (e-PTFE) is used.

Here, it is disadvantageous that these known implants for being pushed in growth of cell tissue in their microporous structure for too long need, so that the implant often moves especially in an unfavorable movement from its intended position. In many cases, this means that also further surgery with the above already mentioned risks is necessary.

The invention has the object of providing an implant which quickly forms a bond with a tissue and yet is sufficiently compatible with the tissue.

The object of the invention is achieved by an implant made of a tissue-compatible microporous material having at least a stable opening. A trespassing in contact with the implant tissue can grow relatively rapidly in such an arrangement in the stable opening of the implant.

Advantageously, the tissue-friendly material comprises microporous labile openings. This is particularly advantageous since, virtually any area of ​​the implant is appropriate in addition to the stable openings which serve a fast ingrowth of cellular tissue that tissue may grow in particular in the medium or long term.

in addition to a first rapid fixing possibility of the implant by the fast ingrown into the stable open cellular tissue, this causes a particularly intimate connection between the tissue-compatible microporous material of the implant and arranged around the implant subcutaneous tissue.

It is also advantageous that arise selbildungen no Cape even with larger fillings, as is the case with silicone or almost any other solid implants. Furthermore is achieved by the inventive implant compared to usual implants, such as silicone, saline, soybean oil, a significant weight saving. In particular, leakage of the contents of an implant is excluded in terms of erfindungsge- MAESSEN implant. The implant suffers neither by a pressure or a vacuum momentous injury. Also, the implant is virtually hardly destroyed by puncture or other injuries. In particular to ensure the biocompatibility of the implant, it is advantageous if the implant is made of an expanded polytetrafluoroethylene (e-PTFE) is made. In particular, PTFE is approved in surgery for quite some time and calls yet see out reactions or intolerances no allergic.

As an implant is very soft and elastic from an e-PTFE, it does not come advantageously rarely or pressure points. This is especially beneficial in areas such as nerves, bones, blood vessels, which in particular subsequent pains are virtually eliminated.

With the expanded polytetrafluoroethylene is advantageously provided a microporous material available, whose material is so widely expanded can respectively be that a tissue and / or a vessel through the microporous material may grow through itself and thus the implant has a very intimate connection with the received tissue.

The stable foraminous microporous material made of an expanded polytetrafluoroethylene has, in particular due to its porous structure, a ratio of preferably only 14% material and 86% air.

Here, the micro-porosity or unstable holes ensure that medium to long term tissue penetrate the material or can grow together with this. The implant with stable openings suitable to even the smallest tissue and / or node distances (both benign and malignant) which are well visible, for example, after an intervention by the sinking skin due to a tissue defect, replenish, as the implant is preferably in each to-cut any length, and thus virtually any missing tissue, whose shape and size was not fixed prior to a surgical insert can be replaced. For example, a skein may be formed, which can be used in place of the removed tissue from the implant. The band-shaped implant per se, which is shaped into a ball or egg ner similar three-dimensional arrangement, thus forming a lattice structure which can be penetrated in the long tissue.

The inventive implant has a single substance, which preferably contains no filling, wherein the disadvantage of diffusion of liquids conventional implants advantageously is not given.

It is understood that the inventive implant can be found as a supporting element or as a tissue replacement not only in human medicine but also in veterinary medicine application.

In order to realize an intimate connection between a tissue and the implant by means of the stable openings quickly as possible, it is advantageous if at least a stable open a substantially perpendicular to the implant surface minimum diameter of 30 microns and 50 microns, preferably a minimum diameter of 1 mm, having. This ensures that a fabric especially quickly grow into the microporous material of the implant.

In particular, the openings can be selected so large that tissue or similar structures, these openings after insertion of the implant extent penetrate that these come back with the body's own tissue or other body structures in contact. The thus-related adhesions lead directly to a stabilization of the implant in the body. The contact also promotes a possible coalescence, which is then much faster proceeds. It is also conceivable that it - takes a little longer until they enter into their own relatively large openings or waxing - especially in more stable and harder structures. However this is much faster than is the case with the smallest or labile openings.

Thus, the implant material is still sufficiently particular available, it is advantageous if at least a stable opening located a substantially perpendicular to the implant surface diameter of less than 5 mm, preferably a diameter of less than or equal to 4 mm,.

It is particularly advantageous if the stable openings of the microporous material, particularly in a standing under load in the opening plane of the implant, are open such that its minimum diameter is greater than the minimum diameter of the labile openings. Is In this way the risk can be mitigated, that an inserted recently implant shifts by an unfavorable movement or for example by a coughing process such that a renewed surgical intervention is necessary.

This distinguishes the implant of known implants according to the invention, since the pores of a known microporous material are closed depending on the load of the implant or from the outset such that ingrowth of tissue greatly hindered or is almost impossible. This is partly because that individual fibers of the known implants are tightened in many load conditions so as to constrict the pores in each case between them in such a way, sealed, that the implant surrounding tissue hardly and if then very slowly grow into the pores ,

However, the stable openings of the implant according to the invention, however, remain so wide open that the microporous material surrounding tissue may advantageously be able to grow quickly in the stable openings and thus as quickly as possible to ensure at least a basic fixation of the implant within the tissue at all the application-related loads. In particular, the risk of slippage in this case can be greatly reduced soon after surgery.

The size of the stable openings or the microstructure can be adapted to the respective application in the context of the invention, wherein the stable openings sufficiently large for rapid penetration of the particular tissue and the microstructure sufficiently rigid for the loads required and sufficiently for a long-term ingrowth the fabric should be selected.

It is understood that the stable openings can have virtually any technically feasible hole shape. It is particularly advantageous if at least a stable opening has a circular or oval shape.

Furthermore, the stable openings can be arranged at any distance to each other, it was found that it is advantageous for the stable openings a distance of at least 0.5 mm, preferably a distance of at least 1 mm, from one another.

It is understood that the stable openings may be generally arranged in almost any configuration to the implant.

It is advantageous, in particular with respect to a Vaginalbandes when the implant is tubular or ribbon-shaped. The implant is preferably formed as an e-polytetrafluoroethylene tape. The implant may be varied in terms of its width, height, or shape, with a rectangular shape with 1 mm width and 10 mm is preferred.

While preferably an implant with a connecting means is applied to a TVT at both ends for the application, an implant as tissue substitute may be preferably provided as tape material on a roll. In this case, an oval band may be advantageous, since this provides volume in a suitable manner. In manufacturing, in particular, a rectangular band which is easier to work is. In a tape as tissue substitute a rectangular shape with 1.5 mm high and 4 mm wide is preferred for these reasons. In particular, the implant can be in the form of a ribbon particularly favorable to a conglomerate through a small incision or through one or more small incisions are freely inserted, wherein a loose thereby arbitrarily large implant can be prepared, inter alia.

An embodiment variant provides that the implant is at least one

having connecting means by means of which a further component with

can be connected> the implant. In particular to bear the rather soft implant through tissue, it is advantageous if the implant comprises a connecting means on which a fixed member for guiding can be attached, for example, easily.

It is understood that the connecting device be attached depending on the application intraoperatively to the implant or may be already arranged at the factory on the implant.

It is advantageous if the connecting device has means for interlocking connection. This can quickly established a good durable bond. In particular, the connection means may comprise a thread. In this way, for example, ensures that virtually any component can be quickly and easily attached to the implant. The device requires only a Verbindungseinrich- the thread of the processing corresponding counter thread.

On the other hand, the connecting means may also include means for friction bonding.

The skilled artisan will appreciate that the connection means of the implant can be realized by a variety of technical equipment such as, for example, plug or clamp connections. It is understood that such a connecting device, in particular if it is already at the factory connected to the implant, is advantageous irrespective of the other characteristics of the invention, in order to ensure reliable insertion of an implant quickly and reliably.

A further embodiment provides that eimichtung where it attaches a guide means is mounted, with which the implant can be guided in particular by a fabric. The guide means makes it possible to guide the implant, for example during a surgical applications in the treatment of urinary incontinence advantageous tongues without serious consequences injury through the tissue of the body. Preferably, the guide means with respect to the connecting means of the implant has no palpable and / or visible transition. For this, the guide means may for example be a blunt needle or a Pilotpin. In particular, a blunt needle allows example, in a incontinence operation, an insertion of the implant in a very short time, with the risk fäßverletzung with respect to a tissue and / or Ge, for example, injuries to the bladder and the urethra is greatly minimized.

In order to guide the implant advantageously by a fabric, it is advantageous if the guide means is bent.

In particular the Fülirungsmittel to mount quickly and easily to the measure implant, it is advantageous if the guide means comprises a clutch device which communicates with the connecting means of the implant. For example, the connecting means of the implant is externally threaded and the coupling means of the guide means to a corresponding external thread of the internal thread, so that the guide means can be very easily attached to the implant.

Among other things, the risk of tissue injury may be further reduced, it is advantageous if the guide means at the opposite end of the coupling device concavely curved, preferably spherically rounded. By a relatively coarse structure to this end, the tissue is only injured in a reasonable frame. In the present context, the average curvature radius of the tip should be not less than 50 μ, preferably about 100 μ and 300 μ. are to avoid injury if possible. Among the average radius of curvature in this regard, a radius of the tip accessible from one side of the tip and then beaten on the other side of the semi-circle is meant in which both mutually as well as the tip itself lying on this semi-circle, while the remaining components of the top outside or are arranged in this semi-circle.

Preferably, the concave end is polished in order to minimize the risk of injury.

The risk of tissue or vascular injury can be minimized in addition, when the clutch means of the guide means and the connecting means of the implant have an identical outer diameter. In this way a nearly seamless connection between the guide means and the implant can be manufactured in particular. This facilitates, among others, guiding the erfindungsge- MAESSEN implant through a body essential since no transitions between the guide means and the implant when driving through a tissue is a hindrance. In addition, possible to dispense with a protective tube or a protective shell between the implant and which is pierced a tissue.

To drive the guide means simple and yet gently through a body or through tissue, it is advantageous when the guide means comprises a vibration device. Thereby caused, a high pressure on the Fülirungsmittel need not, as previously exerted to move DIE ses through the body, but the implant is moved due to the vibrations of the guiding means almost independently through the tissue of the body. Among other things, thus the risk of injury to internal organs such as a bladder or blood vessels is reduced even further. In addition, thus the operation time is reduced significantly. For example, the implant during an operation for inserting a Vaginalbandes in less than 20 minutes can be used, possibly even under local anesthesia.

It is understood that the vibration device may be either externally mounted on the guide means and arranged internally in the guide means. Moreover, the vibration device may bring the guide means directly or by means of a flexible extension to vibrate.

Preferably, the vibration device is arranged in the region of the coupling device or in the vicinity of the coupling means of the guide means, so that the latter can be introduced readily.

In order to reduce the total cost, it is advantageous if the guide means is constructed such that it can be used at least after a first use for a second time.

Preferably, the connecting means and / or the guide means and / or the coupling means of the guide means made of V4A is made. In this way, they are extremely durable and easily sterilized. In addition, this material is already well-proven in medical technology.

It is understood that the devices and means mentioned above may also be made of other materials. This applies in particular then sondere, albeit these materials meet the strict medical standards.

In particular, it is possible when using the implant previously described, to dispense with the previously required hose or plastic bags when feeding the implant into a tissue. Among other things, it is also ensured thereby that the implant is especially close to the piercing tissue, which makes a faster tissue ingrowth into the microporous material of the implant. Also remains at a point of penetration of the skin, only a relatively small scar, approximately corresponds to the diameter of the guide means there need not be increased unnecessarily due to the identical outer diameter and due to the existing tubular casing or plastic shell of the section for piercing. This reduces inter alia, the wound pain of a patient.

It is understood that both the above-described guide means and the vibration device and the coupling between the guide means and implant even without the other features of the invention are advantageous. is meant by the term "labile opening" according to the invention pores of the microporous material, which is closed completely or so far at an application-specific load distribution in the microporous material in the worst case, so that in the labile openings to-least temporarily no cell tissue can grow.

is meant by the term "stable open" in the sense of the invention, those pores of the microporous material, the loading true at a application-specific load distribution in the microporous material even in a worst case, the load application a minimum diameter, so that in the stable openings almost anytime penetrate a cell or tissue ingrowth.

A microporous material as described above can be produced particularly simply, it is advantageous if the microporous material is an expanded polytetrafluoroethylene (e-PTFE). Particularly in a e-PTFE material, the fibrils can grow almost at will and thus produce a different textured microporous material simple and inexpensive. In addition, so far been re intolerances or allergies completely unremarkable e-PTFE in particular with respect of medical applications.

The object of the invention is also achieved by a method for introducing a reinforcing member in an area surrounded by a sheath soft structure, in which the reinforcing member from a first region of the sheath into the soft structure, the encryption strengthening element up to a second region of the case made by the soft structure and guided outwardly therefrom, and wherein the overwrap in the second region from the outside of the reinforcing member permeable and the reinforcing member is then passed through the second area to the outside.

it when previously, the reinforcing member is located in the second portion of the envelope from the outside, so that the envelope can be opened selectively at this point is advantageous.

It is particularly advantageous if a part of the reinforcing element mapping for permeabilizing the envelope to the second region. Characterized in that the reinforcing element or at least part thereof forms its images on the casing may very well be determined from the outside, at which point the envelope, the reinforcing member is located. Thereby, the location of the sleeve for the reinforcement element can be made selectively permeable from outside.

The method is suitable, for example, with regard to use in connection with surrounded by a sheath aerosols. Also other soft materials, which are surrounded by a harder shell and which are to be reinforced by a reinforcing member may be treated in this manner. In particular, this method is also suitable for feeding an implant in a body. Here, the casing or skin is first opened at a first location such that the reinforcing element or an implant, optionally would take under Zuhilfe- of the guide means in the material or guided in the body and this is driven through this or, to the shell or the skin is achieved at a second location. There, the reinforcing agent, the implant or the guiding means can be located and the shell or skin are again opened from the outside, for example by a cut.

De Further, the object of the invention solved by a method for manufacturing an implant from a blank, wherein the blank is formed intraoperatively into an implant. Since almost never zutref- the extent of tissue removal, for example, prior to an operation can be determined fend, it is now possible to directly intraoperatively adjust the implant to the extent of tissue sampling occurred.

It is particularly advantageous when the blank is cut to length intraoperatively to an implant is. In particular directly during surgery, for example for introducing a tissue replacement, it is advantageous if the implant can be exactly adapted to the operating conditions by the blank can be cut to length intraoperatively. For example, in a TVT, this - possibly even after days - happen when the implant is already being used.

Further advantages, objects and features of the present invention will be explained with reference to the description of the attached drawing, in which exemplary embodiments shown with respect to the inventive implant. Show it

Figure 1 is a schematic view of a first arrangement variation stable openings of an implant,

Figure 2 is a schematic view of a second arrangement variation stable openings of an implant,

Figure 3 is a schematic cross sections of some implants,

Figure 4 is a schematic illustration of an implant with a guide means and a vibration means

Figure 5 is a schematic representation of another implant with a connecting device.

The implant 1 depicted in Figure 1 is made from a flat strip. 2 The ribbon 2 in this case comprises a plurality of holes 3, 4, 5, 6, 7 and 8, which are introduced as a stable openings in the implant. 1 The holes 3 to 8 are arranged in this case in each case essentially at an equal distance-each other in a longitudinal direction 9 of the flat strip. 2

In contrast, the implant 10 has at its flat band-like configured body 11 a number of each other in a longitudinal orientation 12 offset holes 13, 14, 15, 16, 17 and 18. The holes 13 to 18 are even in the longitudinal direction 12 of the body 11 disposed of the implant 10, but the holes are 13, 15 and 17 closer to a side area 19 of the implant 10, whereas the holes 14, 16 and 18 rather arranged in a side region 20 of the implant 10 degrees.

In the Figure 3 cross-sections 21, 22, 23, 24 and 24 A different implants are shown. The cross-section 21 here corresponds to a band-oval, the cross section 22 corresponding to a flat band. The cross section 23 has a circular shape, while the cross section 24 is rectangular, in particular square shaped. The reference numeral 24 A, a hose is designated. This may be unstable on the one hand formed Eigent or rigid in itself.

The implant 25 shown in Figure 4 comprises an expanded Polytet- rafluorethylen band 26, which is disposed with a stainless steel screw 27 to an inner thread 28 of a curved needle 29th

The expanded polytetrafluoroethylene tape 26 has a plurality of labile openings 30 (only exemplarily numbered) and a plurality of stable openings 31 (also numbered only as examples).

The curved needle 29 comprises the region of its tip 32 a polished ball-shaped tip 33. The tip of each rounded tip comes into question, have an average radius of curvature greater than 50 μ, preferably greater than 300 μ, having.

The implant 25 and the curved needle 29 know in a region 34, which is preferably arranged in the vicinity of the internal thread 28, a vibrator 35th By means of the vibrator 35, the needle is so offset 29 in particular in the area of ​​the polished ball-like tip 33 to vibrate, that the implant 25 can be moved advantageously in the thrust direction 36 by a web 36A. To achieve with the implant 25, the tissue 36 A, is - optionally - a skin puncture 36B which is arranged around the tissue 36 A. This can be by known methods, such as a small incision happen, so that it can be dispensed with a sharp needle which can pierce the skin independently. Accordingly, the guide means or the implant 25 may then again be led out, in which it is guided up to the skin and 36B located there. the guide means or the implant can then be removed 25 by a small incision.

The vibrator 35 transmits vibrations by means of an extension 37 to the needle 29 of the implant 25th

The implant 38 (Figure 5) comprises a plurality of stable openings 39 (numbered only as examples here) as well as at one end 40 of a screw 41, which is clamped with its portion 42 with a polytetrafluoroethylene tape 43 of the implant 38th

Claims

claims:
1. An implant (1; 10; 25; 38) made of a tissue-compatible microporous material, characterized by at least a stable opening (31; 39).
2. The implant (1; 10; 25; 38) according to claim 1, characterized in that the tissue-friendly microporous material labile openings (30).
is made of an expanded polytetrafluoroethylene (e-PTFE) 3. The implant (1; 10; 25; 38) according to any one of claims 1 or 2, characterized in that the implant (38 1; 10;; 25).
4. The implant (1; 10; 25; 38) according to any one of claims 1 to 3, characterized in that at least a stable opening (31; 39) has a substantially perpendicular to the implant surface minimum diameter of 30 μ and 50 microns, preferably has a minimum diameter of 1 mm.
5. The implant (1; 10; 25; 38) according to any one of claims 1 to 4, characterized in that at least one stable opening (31; 39) has a substantially perpendicular to the implant surface diameter of less than 5 mm, preferably a diameter of below or equal to 3 mm.
6. An implant (1; 10; 25; 38) according to one of claims 1 to 5, characterized in that the stable openings (31; 39) with respect to the labile openings (30), particularly in a standing under load in the opening plane implant (1; 10; 25; 38) are open such that its minimum diameter is greater than the
Minimum diameter of the labile openings (30).
7. The implant (1; 10; 25; 38) according to any one of claims 1 to 6, characterized in that at least one stable opening (31; 39) has a circular or oval shape.
8. The implant (1; 10; 25; 38) according to any one of claims 1 to 7, characterized in that the stable openings (31; 39) a distance of at least 0.5 mm, preferably a distance of at least 1 mm, with each other respectively.
9. The implant (1; 10; 25; 38) according to any one of claims 1 to 8, characterized in that the implant (1; 10; 25; 38) is tubular or ribbon-shaped.
10. An implant (1; 10; 25; 38) according to any one of claims 1 to 9, characterized in that the implant (1; 10; 25; 38) has at least one connecting device, by means of which another construction part with the implant can be connected.
11. An implant (1; 10; 25; 38) according to claim 10, characterized in that the connecting device has means for interlocking connection.
12. An implant (1; 10; 25; 38) according to claim 10 or 11, characterized indicates overall that the connection means comprises a thread.
13. An implant (1; 10; 25; 38) according to claim 10, characterized in that the connection means includes means for friction bonding.
14. An implant (1; 10; 25; 38) according to one of claims 10 to 13, characterized in that by means of the connecting means, a guide means is connected to the implant with which the implant (1; 10; 25; 38), in particular may be passed through a tissue.
15. An implant (1; 10; 25; 38) according to claim 14, characterized in that the guide means at the opposite end of the coupling device concavely curved, preferably spherically rounded.
16. An implant (1; 10; 25; 38) according to claim 15, characterized gekennzeich- net, that the concavely curved end is polished.
17. An implant (1; 10; 25; 38) according to any one of claims 14 to 16, characterized in that the guide means comprise a blunt needle (29).
18. An implant (1; 10; 25; 38) according to any one of claims 14 to 17, data carried in that the guide means is bent.
19. An implant (1; 10; 25; 38) according to any one of claims 14 to 18, characterized in that the guide means comprises a clutch device, which with the connecting means of the implant (1; 38 10;; 25) communicates.
20. An implant (1; 10; 25; 38) according to claim 19, characterized in that the coupling means of the guide means and the connecting means of the implant have an identical outer diameter.
21. An implant (1; 10; 25; 38) according to any one of claims 14 to 20, data carried in that the guide means comprises a vibration device.
22. Implant according to one of claims 1 to 21, characterized in that the microporous material comprises a multiplicity of fibrils, wherein said fibrils in the area of ​​their ends are group-penweise interconnected.
23. The implant of claim 22, characterized in that the fibrils form labile openings about 30 microns and 50 microns.
24. A method for introducing a reinforcing member in an area surrounded by a sheath soft structure, in which the reinforcement element from a first region of the shell, starting in the soft structure in until a second portion of the sheath by the soft structure and outwardly is guided, characterized in that the sheath in the second region from the outside made permeable for the reinforcing element and the comparison is then performed strengthening element through the second area to the outside.
25, installation methods according to claim 26, characterized in that before, the reinforcing member is located in the second region of the sleeve from the outside.
26, installation methods according to one of claims 24 or 25, characterized in that the permeabilizing a part of the reinforcing element is imaged on the second area.
27. A method for producing an implant (1; 10; 25; 38) from a blank, characterized in that the blank intraope--operatively to an implant (1; 10; 25; 38) is formed.
28. The manufacturing method according to claim 27, characterized in that the blank is cut to length intraoperatively.
PCT/DE2001/004722 2000-12-16 2001-12-14 Implant, method for inserting a reinforcing element, and method for producing an implant WO2002047578A1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
DE10062691 2000-12-16
DE20022228.7 2000-12-16
DE2000222228 DE20022228U1 (en) 2000-12-16 2000-12-16 Punched e-PTFE tape for surgical implants
DE10062691.2 2000-12-16
DE10156594 2001-11-20
DE10156594.1 2001-11-20
DE10156592 2001-11-20
DE10156592.5 2001-11-20

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10450688 US20040049289A1 (en) 2000-12-16 2001-12-14 Implant, method for inserting a reinforcing element, and method for producing an implant
EP20010995601 EP1345553A1 (en) 2000-12-16 2001-12-14 Implant, method for inserting a reinforcing element, and method for producing an implant
JP2002549156A JP2004515306A (en) 2000-12-16 2001-12-14 Implant procedure the introduction of reinforcing elements, and an implant manufacturing process

Publications (1)

Publication Number Publication Date
WO2002047578A1 true true WO2002047578A1 (en) 2002-06-20

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PCT/DE2001/004722 WO2002047578A1 (en) 2000-12-16 2001-12-14 Implant, method for inserting a reinforcing element, and method for producing an implant

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EP (1) EP1345553A1 (en)
JP (1) JP2004515306A (en)
CN (1) CN1489449A (en)
WO (1) WO2002047578A1 (en)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5122155A (en) * 1990-10-11 1992-06-16 Eberbach Mark A Hernia repair apparatus and method of use
US5290217A (en) * 1991-10-10 1994-03-01 Earl K. Sipes Method and apparatus for hernia repair
WO1994019029A1 (en) * 1993-02-18 1994-09-01 W.L. Gore & Associates, Inc. A laminated patch tissue repair sheet material
WO1995030374A1 (en) * 1994-05-06 1995-11-16 Origin Medsystems, Inc. Apparatus and method for delivering a patch
FR2741523A1 (en) * 1995-11-23 1997-05-30 Prothia Sarl Device for retracting implanted articles in human body
WO1999016381A1 (en) * 1997-10-01 1999-04-08 Boston Scientific Limited Pelvic floor reconstruction
US5922026A (en) * 1997-05-01 1999-07-13 Origin Medsystems, Inc. Surgical method and prosthetic strip therefor
US5972007A (en) * 1997-10-31 1999-10-26 Ethicon Endo-Surgery, Inc. Energy-base method applied to prosthetics for repairing tissue defects

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5122155A (en) * 1990-10-11 1992-06-16 Eberbach Mark A Hernia repair apparatus and method of use
US5290217A (en) * 1991-10-10 1994-03-01 Earl K. Sipes Method and apparatus for hernia repair
WO1994019029A1 (en) * 1993-02-18 1994-09-01 W.L. Gore & Associates, Inc. A laminated patch tissue repair sheet material
WO1995030374A1 (en) * 1994-05-06 1995-11-16 Origin Medsystems, Inc. Apparatus and method for delivering a patch
FR2741523A1 (en) * 1995-11-23 1997-05-30 Prothia Sarl Device for retracting implanted articles in human body
US5922026A (en) * 1997-05-01 1999-07-13 Origin Medsystems, Inc. Surgical method and prosthetic strip therefor
WO1999016381A1 (en) * 1997-10-01 1999-04-08 Boston Scientific Limited Pelvic floor reconstruction
US5972007A (en) * 1997-10-31 1999-10-26 Ethicon Endo-Surgery, Inc. Energy-base method applied to prosthetics for repairing tissue defects

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JP2004515306A (en) 2004-05-27 application
EP1345553A1 (en) 2003-09-24 application
CN1489449A (en) 2004-04-14 application

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