WO2002045695A3 - Hydrostatic delivery system for controlled delivery of agent - Google Patents

Hydrostatic delivery system for controlled delivery of agent Download PDF

Info

Publication number
WO2002045695A3
WO2002045695A3 PCT/CA2001/001721 CA0101721W WO0245695A3 WO 2002045695 A3 WO2002045695 A3 WO 2002045695A3 CA 0101721 W CA0101721 W CA 0101721W WO 0245695 A3 WO0245695 A3 WO 0245695A3
Authority
WO
WIPO (PCT)
Prior art keywords
hydrostatic
agent
delivery system
delivery
controlled
Prior art date
Application number
PCT/CA2001/001721
Other languages
French (fr)
Other versions
WO2002045695A2 (en
Inventor
Alexander Macgregor
Original Assignee
Alexander Macgregor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alexander Macgregor filed Critical Alexander Macgregor
Priority to CA002431205A priority Critical patent/CA2431205C/en
Priority to AU2002221412A priority patent/AU2002221412B2/en
Priority to EP01999361A priority patent/EP1347748A2/en
Priority to AU2141202A priority patent/AU2141202A/en
Priority to JP2002547481A priority patent/JP2004513975A/en
Publication of WO2002045695A2 publication Critical patent/WO2002045695A2/en
Publication of WO2002045695A3 publication Critical patent/WO2002045695A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention provides a hydrostatic delivery system comprising a hydrostatic couple and an agent of interest. The hydrostatic couple comprises, at least one hydrodynamic fluid-imbibing polymer, and at least one hydrostatic pressure modulating agent. This delivery system has the ability to control the release of one or more agent of interest within a fluid environment following zero-order kinetics.
PCT/CA2001/001721 2000-12-05 2001-12-04 Hydrostatic delivery system for controlled delivery of agent WO2002045695A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002431205A CA2431205C (en) 2000-12-05 2001-12-04 Hydrostatic delivery system for controlled delivery of agent
AU2002221412A AU2002221412B2 (en) 2000-12-05 2001-12-04 Hydrostatic delivery system for controlled delivery of agent
EP01999361A EP1347748A2 (en) 2000-12-05 2001-12-04 Hydrostatic delivery system for controlled delivery of agent
AU2141202A AU2141202A (en) 2000-12-05 2001-12-04 Hydrostatic delivery system for controlled delivery of agent
JP2002547481A JP2004513975A (en) 2000-12-05 2001-12-04 Hydrostatic delivery system for controlled release of active substance

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25175100P 2000-12-05 2000-12-05
US60/251,751 2000-12-05

Publications (2)

Publication Number Publication Date
WO2002045695A2 WO2002045695A2 (en) 2002-06-13
WO2002045695A3 true WO2002045695A3 (en) 2002-12-27

Family

ID=22953251

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2001/001721 WO2002045695A2 (en) 2000-12-05 2001-12-04 Hydrostatic delivery system for controlled delivery of agent

Country Status (6)

Country Link
US (2) US7381424B2 (en)
EP (1) EP1347748A2 (en)
JP (1) JP2004513975A (en)
AU (2) AU2002221412B2 (en)
CA (1) CA2431205C (en)
WO (1) WO2002045695A2 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004513975A (en) * 2000-12-05 2004-05-13 マクグレゴール アレキサンダー Hydrostatic delivery system for controlled release of active substance
US20040219210A1 (en) * 2003-05-01 2004-11-04 Jian-Hwa Guo Controlled release solid dosage nifedipine formulations
CA2569968C (en) * 2004-06-10 2014-08-19 Glatt Air Techniques, Inc. Controlled release matrix pharmaceutical dosage formulation
MX2007005277A (en) 2004-11-02 2008-03-11 Gangagen Life Sciences Inc Stabilized bacteriophage formulations.
US8017032B2 (en) * 2005-03-01 2011-09-13 Truox, Inc. Tablet composition for the in-situ generation of chlorine dioxide for use in antimicrobial applications
US20110027330A1 (en) * 2005-03-01 2011-02-03 Martin Roy W Tablet composition for the in-situ generation of chlorine dioxide for use in antimicrobial applications
US20060197056A1 (en) * 2005-03-01 2006-09-07 Martin Roy W Solvent-activated reactor using colloidal gel
US20090208547A1 (en) * 2005-03-01 2009-08-20 Roy William Martin Oxidizing composition including a gel layer
US7534368B2 (en) * 2005-03-01 2009-05-19 Truox, Inc. Oxidizing composition including a gel layer
US7514019B2 (en) * 2005-03-01 2009-04-07 Truox, Inc. Solvent-activated reactor including a gel layer
US7993545B2 (en) * 2005-03-01 2011-08-09 Truox, Inc. Tablet composition for the in-situ generation of chlorine dioxide for use in antimicrobial applications
MX2008013675A (en) 2006-04-26 2009-03-06 Supernus Pharmaceuticals Inc Controlled released preparations of oxcarbazepine having sigmoidal release profile.
US7964182B2 (en) * 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
EP2064252A2 (en) * 2006-09-01 2009-06-03 Usv Limited Process for the preparation of sevelamer hydrochloride and formulation thereof
CN101284879B (en) * 2007-04-09 2010-07-21 东莞东美食品有限公司 Preparation method of oxidized starch
US20080292692A1 (en) * 2007-05-21 2008-11-27 Shira Pilch Impermeable Capsules
ES2405774T3 (en) 2007-10-11 2013-06-03 Inserm (Institut National De La Sante Et De La Recherche Scientifique) Methods for preparing porous scaffolding for tissue engineering
US7928189B2 (en) 2008-05-05 2011-04-19 Ottawa Health Research Institute PCSK9 polypeptide fragment
EP2389168A2 (en) * 2009-01-22 2011-11-30 USV Limited Pharmaceutical compositions comprising phosphate-binding polymer
US9675065B2 (en) 2011-02-14 2017-06-13 Truox, Inc. Biocide and bleach compositions and related methods
WO2013028624A1 (en) * 2011-08-19 2013-02-28 Ho Rodney J Y Compositions, devices, and methods for treating infections
US8999393B1 (en) 2013-01-09 2015-04-07 Edgemont Pharmaceuticals Llc Sustained release formulations of lorazepam
SG11201505352RA (en) 2013-01-09 2015-08-28 Edgemont Pharmaceuticals Llc Controlled release formulations of lorazepam
US9132096B1 (en) 2014-09-12 2015-09-15 Alkermes Pharma Ireland Limited Abuse resistant pharmaceutical compositions
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
EP3288570A4 (en) 2015-04-29 2018-11-21 Fred Hutchinson Cancer Research Center Modified stem cells and uses thereof
ES2898930T3 (en) * 2015-06-01 2022-03-09 Xeno Biosciences Inc Compositions for use in modulating the gut microbiota and weight management
PT109154B (en) * 2016-02-12 2019-11-05 Univ De Coimbra NON-INVASIVE EYE INSERT TECHNOLOGY FOR CONTROLLED DRUG RELEASE
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB905000A (en) * 1960-06-06 1962-09-05 American Home Prod Improvements in and relating to sustained and delayed release oral medicaments
EP0486863A1 (en) * 1990-11-17 1992-05-27 Bayer Ag Antiacid compositions with prolonged gastric residence time

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2909462A (en) 1955-12-08 1959-10-20 Bristol Myers Co Acrylic acid polymer laxative compositions
US3042667A (en) 1959-03-10 1962-07-03 Pharmacia Ab Process for producing dextran derivatives and products resulting therefrom
US3033754A (en) 1959-12-21 1962-05-08 Lakeside Lab Inc Tablets containing hydrazine derivatives
SE358894B (en) 1961-10-25 1973-08-13 Pharmacia Ab
US3330729A (en) 1963-10-04 1967-07-11 Goodrich Co B F Sustained release tablet containing medicament admixed in a waterinsoluble acrylic acid cross-linked polymer and selected basic magnesium or calcium diluent
CH415963A (en) 1964-09-04 1966-06-30 Wander Ag Dr A Compound for the production of tablets with protracted action
US3458622A (en) 1967-04-07 1969-07-29 Squibb & Sons Inc Controlled release tablet
US3538214A (en) 1969-04-22 1970-11-03 Merck & Co Inc Controlled release medicinal tablets
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4002173A (en) 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
US4248857A (en) 1979-08-09 1981-02-03 American Home Products Corporation Sustained release pharmaceutical compositions
DE3239476C2 (en) 1981-10-26 1984-06-20 Arakawa Kagaku Kogyo K.K., Osaka Process for producing a solid, dry and water-absorbent resin
US5082668A (en) 1983-05-11 1992-01-21 Alza Corporation Controlled-release system with constant pushing source
US4680323A (en) 1983-12-01 1987-07-14 Hans Lowey Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration
US4601894A (en) 1985-03-29 1986-07-22 Schering Corporation Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate
US4624847A (en) 1985-04-22 1986-11-25 Alza Corporation Drug delivery device for programmed delivery of beneficial drug
US4755386A (en) 1986-01-22 1988-07-05 Schering Corporation Buccal formulation
US4687757A (en) 1986-03-24 1987-08-18 Phillips Petroleum Company Hydrofining catalyst composition and process for its preparation
US4820773A (en) 1986-04-21 1989-04-11 American Colloid Company Water absorbent resins prepared by polymerization in the presence of styrene-maleic anhydride copolymers
US4994276A (en) 1988-09-19 1991-02-19 Edward Mendell Co., Inc. Directly compressible sustained release excipient
CA2041774C (en) 1990-11-27 1994-04-19 Mircea A. Mateescu Use of cross-linked amylose as a matrix for the slow release of biologically active compounds
US5357636A (en) * 1992-06-30 1994-10-25 Dresdner Jr Karl P Flexible protective medical gloves and methods for their use
GB9505032D0 (en) 1995-03-13 1995-05-03 Westminster Lab Ltd Improvements in or relating to organic compositions
US5582838A (en) * 1994-12-22 1996-12-10 Merck & Co., Inc. Controlled release drug suspension delivery device
US5837284A (en) * 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
IT1282650B1 (en) * 1996-02-19 1998-03-31 Jagotec Ag PHARMACEUTICAL TABLET, CHARACTERIZED BY A HIGH INCREASE IN VOLUME IN CONTACT WITH BIOLOGICAL LIQUIDS
US6071539A (en) * 1996-09-20 2000-06-06 Ethypharm, Sa Effervescent granules and methods for their preparation
WO1998020872A1 (en) * 1996-11-14 1998-05-22 Halldor Thormar Topical formulations containing as a therapeutic active agent fatty acids or fatty alcohols or monoglyceride derivatives thereof for treating of mucosa infections
US6131570A (en) * 1998-06-30 2000-10-17 Aradigm Corporation Temperature controlling device for aerosol drug delivery
US5807575A (en) 1997-02-14 1998-09-15 Rougier Inc. Manufacture of cross-linked amylose useful as a excipient for control release of active compounds
US5840329A (en) * 1997-05-15 1998-11-24 Bioadvances Llc Pulsatile drug delivery system
US6200604B1 (en) * 1998-03-27 2001-03-13 Cima Labs Inc. Sublingual buccal effervescent
WO2000015198A1 (en) * 1998-09-14 2000-03-23 Ranbaxy Laboratories Limited Orally administered controlled drug delivery system providing temporal and spatial control
JP2004513975A (en) * 2000-12-05 2004-05-13 マクグレゴール アレキサンダー Hydrostatic delivery system for controlled release of active substance

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB905000A (en) * 1960-06-06 1962-09-05 American Home Prod Improvements in and relating to sustained and delayed release oral medicaments
EP0486863A1 (en) * 1990-11-17 1992-05-27 Bayer Ag Antiacid compositions with prolonged gastric residence time

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DORKOOSH F A ET AL: "Preparation and NMR characterization of superporous hydrogels (SPH) and SPH composites", POLYMER, ELSEVIER SCIENCE PUBLISHERS B.V, GB, vol. 41, no. 23, November 2000 (2000-11-01), pages 8213 - 8220, XP004209739, ISSN: 0032-3861 *
GUL M K ET AL: "Formulation and in vitro evaluation of ibuprofen-carbopolR) 974P-NF controlled release matrix tablets III: influence of co-excipients on release rate of the drug", JOURNAL OF CONTROLLED RELEASE, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, vol. 54, no. 2, 31 July 1998 (1998-07-31), pages 185 - 190, XP004134566, ISSN: 0168-3659 *
See also references of EP1347748A2 *

Also Published As

Publication number Publication date
JP2004513975A (en) 2004-05-13
US20020155067A1 (en) 2002-10-24
AU2002221412B2 (en) 2006-04-13
CA2431205A1 (en) 2002-06-13
US7381424B2 (en) 2008-06-03
US8231897B2 (en) 2012-07-31
AU2141202A (en) 2002-06-18
EP1347748A2 (en) 2003-10-01
WO2002045695A2 (en) 2002-06-13
US20080317847A1 (en) 2008-12-25
CA2431205C (en) 2005-08-23

Similar Documents

Publication Publication Date Title
WO2002045695A3 (en) Hydrostatic delivery system for controlled delivery of agent
CA2502399A1 (en) Hydraulic fluid distribution system
GB2339249B (en) Variable presure hydraulic systems
WO2002060582A3 (en) Microfluidic devices for introducing and dispensing fluids from microfluidic systems
AU6033098A (en) Fluid pressure reduction device
WO2002055128A3 (en) Fluid delivery and measurement systems and methods
MXPA03007291A (en) Hydraulic fracturing fluid comprising a block copolymer containing at least one water-soluble block and one hydrophobic block.
AU2001223525A1 (en) Armoured, flexible pipe and use of same
AU4248500A (en) Fluid pressure reduction device with tortuous paths
AU2002240386A1 (en) Catheter fluid control system
DK0825348T3 (en) Pressure amplifier for liquids, especially hydraulic fluids
GB0009735D0 (en) Formulation
AU2002361005A1 (en) Pharmaceutical composition comprising an oil/water/oil double microemulsion incorporated into a solid support
EP1180460A3 (en) Hydraulic braking system including power-operated pressure source device, and device for controlling pressure output of the pressure source device
ES2165909T3 (en) HYDRAULIC COUPLING WITH ADJUSTABLE PRESSURE DISCHARGE VALVE.
TW200628667A (en) Chemical composition and process
MY118530A (en) Method and compositions for minimizing biological and colloidal fouling
WO1994011424A3 (en) Ink eradicator system
ZA200109593B (en) Fluid flow and pressure control system and method.
WO2001077551A3 (en) Pressure relief device for a sealed system
BR0008564A (en) Presence detection sensor for intelligent airbag systems
FR2710954B1 (en) Electro-hydraulic actuator, especially for an anti-lock hydraulic braking system.
WO1999063250A3 (en) Control device for a safety valve
WO2003053767A3 (en) A ram-based positioning system
MY116445A (en) Dual mode emergency braking apparatus and method of use thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2002547481

Country of ref document: JP

Ref document number: 2431205

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2001999361

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2002221412

Country of ref document: AU

WWP Wipo information: published in national office

Ref document number: 2001999361

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642