WO2002043666A3 - Compositions containing an antioxidant such as alpha lipoic acid, carnitine, vitamin c or vitamin e for preventing or inhibiting loss of cognitive function - Google Patents

Compositions containing an antioxidant such as alpha lipoic acid, carnitine, vitamin c or vitamin e for preventing or inhibiting loss of cognitive function Download PDF

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Publication number
WO2002043666A3
WO2002043666A3 PCT/US2001/048665 US0148665W WO0243666A3 WO 2002043666 A3 WO2002043666 A3 WO 2002043666A3 US 0148665 W US0148665 W US 0148665W WO 0243666 A3 WO0243666 A3 WO 0243666A3
Authority
WO
WIPO (PCT)
Prior art keywords
vitamin
antioxidant
carnitine
preventing
cognitive function
Prior art date
Application number
PCT/US2001/048665
Other languages
French (fr)
Other versions
WO2002043666A2 (en
Inventor
Steven Curtis Zicker
Karen J Wedekind
Original Assignee
Colgate Palmolive Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/922,633 external-priority patent/US20020052402A1/en
Application filed by Colgate Palmolive Co filed Critical Colgate Palmolive Co
Priority to EP01992146A priority Critical patent/EP1339404A2/en
Priority to AU2002232616A priority patent/AU2002232616A1/en
Priority to CA002427470A priority patent/CA2427470A1/en
Priority to JP2002545645A priority patent/JP2004514686A/en
Publication of WO2002043666A2 publication Critical patent/WO2002043666A2/en
Publication of WO2002043666A3 publication Critical patent/WO2002043666A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

A composition comprising an antioxidant or mixture thereof in quantities sufficient to prevent, or inhibit, or reverse deterioration of cognitive function.
PCT/US2001/048665 2000-10-31 2001-10-30 Compositions containing an antioxidant such as alpha lipoic acid, carnitine, vitamin c or vitamin e for preventing or inhibiting loss of cognitive function WO2002043666A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP01992146A EP1339404A2 (en) 2000-10-31 2001-10-30 Composition and method
AU2002232616A AU2002232616A1 (en) 2000-10-31 2001-10-30 Compositions containing an antioxidant such as alpha lipoic acid, carnitine, vitamin C or vitamin E for preventing or inhibiting loss of cognitive function
CA002427470A CA2427470A1 (en) 2000-10-31 2001-10-30 Compositions containing an antioxidant such as alpha lipoic acid, carnitine, vitamin c or vitamin e for preventing or inhibiting loss of cognitive function
JP2002545645A JP2004514686A (en) 2000-10-31 2001-10-30 Compositions and methods

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US24451100P 2000-10-31 2000-10-31
US60/244,511 2000-10-31
US25344600P 2000-11-28 2000-11-28
US25344700P 2000-11-28 2000-11-28
US60/253,447 2000-11-28
US60/253,446 2000-11-28
US09/922,633 US20020052402A1 (en) 2000-10-31 2001-08-06 Composition and method
US09/922,633 2001-08-06

Publications (2)

Publication Number Publication Date
WO2002043666A2 WO2002043666A2 (en) 2002-06-06
WO2002043666A3 true WO2002043666A3 (en) 2003-01-30

Family

ID=27500158

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/048665 WO2002043666A2 (en) 2000-10-31 2001-10-30 Compositions containing an antioxidant such as alpha lipoic acid, carnitine, vitamin c or vitamin e for preventing or inhibiting loss of cognitive function

Country Status (6)

Country Link
EP (1) EP1339404A2 (en)
JP (1) JP2004514686A (en)
CN (1) CN1477958A (en)
AU (1) AU2002232616A1 (en)
CA (1) CA2427470A1 (en)
WO (1) WO2002043666A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005185188A (en) * 2003-12-25 2005-07-14 Nichirei Corp Composition containing treated product of acerola and l-carnitine
RU2350124C2 (en) * 2004-01-28 2009-03-27 Нестек С.А. Nutritious composition for improvement of skin condition and prevention of dermal diseases
AU2005309502B2 (en) * 2004-11-24 2011-11-17 Hill's Pet Nutrition, Inc. Methods for increasing the immune response in an animal
US20090176864A1 (en) * 2004-11-24 2009-07-09 Hill's Pet Nutrition, Inc. Methods For Improving Hepatic and Immune Function In An Animal
DK1817058T3 (en) * 2004-11-24 2015-12-07 Hills Pet Nutrition Inc COMPOSITION FOR USE FOR IMPROVING THE hepatic clearance xenobiotics WITH AN ANIMAL
CN101287460B (en) * 2005-08-17 2012-04-25 希尔氏宠物营养品公司 Compositions for the prevention and treatment of kidney disease
CN1895671B (en) * 2005-12-08 2012-11-28 淮北辉克药业有限公司 Compound preparation for treating viral liver disease
CN101045048B (en) * 2006-03-27 2011-05-18 中国科学院上海生命科学研究院 Application of chondriosome nutrient composition
JPWO2008099469A1 (en) * 2007-02-14 2010-05-27 株式会社プロジェクト・エム Compositions and methods for inhibiting lipid peroxidation of erythrocytes
CN102469807A (en) * 2009-07-14 2012-05-23 希尔氏宠物营养品公司 Pet food compositions including a sustained-release lipoic acid and methods of manufacture and use thereof
KR20140019827A (en) 2011-04-05 2014-02-17 론자 아게 (론자 엘티디.) Use of l-carnitine, salts and derivatives thereof for reducing or preventing fatigue and improving cognitive function
EP2508179A1 (en) 2011-04-05 2012-10-10 Lonza Ltd. Use of L-Carnitine, salts and derivatives thereof for reducing or preventing fatigue and improving cognitive function
NL2024431B1 (en) 2019-12-11 2021-09-07 Sulfateq Bv Compounds for treatment of alzheimer’s disease

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06199690A (en) * 1992-03-06 1994-07-19 Yunie:Kk Agent for promoting cerebral metabolism and improving cerebral function
DE4343592A1 (en) * 1993-12-21 1995-06-22 Asta Medica Ag Use of lipoic acid cpds. for prodn. of CNS medicaments
US5853747A (en) * 1994-06-27 1998-12-29 Institut De Recherche Biologique Therapeutic and dietetic uses of a brain phospholipid-based complex
US5977162A (en) * 1996-09-16 1999-11-02 Seidman; Michael D. Therapeutic treatment for auditory function
DE19920316A1 (en) * 1999-05-03 1999-12-09 Heinz Kiefer Antioxidant medicament containing vitamins and trace elements, useful e.g. for maintaining cellular function and preventing cancer
WO2000011968A1 (en) * 1998-09-01 2000-03-09 Sigma-Tau Healthscience S.P.A. ANTIOXIDANT COMPOSITION COMPRISING ACETYL L-CARNITINE AND α-LIPOIC ACID
WO2000054754A2 (en) * 1999-03-16 2000-09-21 Merck Patent Gmbh Composition comprising isoquercetin and ascorbic acid in a sustained release form
WO2000057876A1 (en) * 1999-03-26 2000-10-05 Lipogenics, Inc. Novel antioxidant formulations and methods for using them
WO2000076492A1 (en) * 1999-06-15 2000-12-21 Nutri-Logics, Inc. Nutrient formulations for disease reduction, and related treatment and component screening methods
WO2001032168A1 (en) * 1999-11-03 2001-05-10 Juvenon, Inc. Method of treating benign forgetfulness
WO2001058271A1 (en) * 2000-01-25 2001-08-16 Juvenon, Inc. Nutritional supplements for aged pets
WO2001070206A2 (en) * 2000-03-06 2001-09-27 Javor Andras Combination of lecithin with ascorbic acid

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06199690A (en) * 1992-03-06 1994-07-19 Yunie:Kk Agent for promoting cerebral metabolism and improving cerebral function
DE4343592A1 (en) * 1993-12-21 1995-06-22 Asta Medica Ag Use of lipoic acid cpds. for prodn. of CNS medicaments
US5853747A (en) * 1994-06-27 1998-12-29 Institut De Recherche Biologique Therapeutic and dietetic uses of a brain phospholipid-based complex
US5977162A (en) * 1996-09-16 1999-11-02 Seidman; Michael D. Therapeutic treatment for auditory function
WO2000011968A1 (en) * 1998-09-01 2000-03-09 Sigma-Tau Healthscience S.P.A. ANTIOXIDANT COMPOSITION COMPRISING ACETYL L-CARNITINE AND α-LIPOIC ACID
WO2000054754A2 (en) * 1999-03-16 2000-09-21 Merck Patent Gmbh Composition comprising isoquercetin and ascorbic acid in a sustained release form
WO2000057876A1 (en) * 1999-03-26 2000-10-05 Lipogenics, Inc. Novel antioxidant formulations and methods for using them
DE19920316A1 (en) * 1999-05-03 1999-12-09 Heinz Kiefer Antioxidant medicament containing vitamins and trace elements, useful e.g. for maintaining cellular function and preventing cancer
WO2000076492A1 (en) * 1999-06-15 2000-12-21 Nutri-Logics, Inc. Nutrient formulations for disease reduction, and related treatment and component screening methods
WO2001032168A1 (en) * 1999-11-03 2001-05-10 Juvenon, Inc. Method of treating benign forgetfulness
WO2001058271A1 (en) * 2000-01-25 2001-08-16 Juvenon, Inc. Nutritional supplements for aged pets
WO2001070206A2 (en) * 2000-03-06 2001-09-27 Javor Andras Combination of lecithin with ascorbic acid

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 199433, Derwent World Patents Index; Class B05, AN 1994-269367, XP002210667 *
POULIN J E ET AL: "Vitamin E prevents oxidative modification of brain and lymphocyte band 3 proteins during aging.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. UNITED STATES 28 MAY 1996, vol. 93, no. 11, 28 May 1996 (1996-05-28), pages 5600 - 5603, XP002210596, ISSN: 0027-8424 *
See also references of EP1339404A2 *

Also Published As

Publication number Publication date
CA2427470A1 (en) 2002-06-06
CN1477958A (en) 2004-02-25
EP1339404A2 (en) 2003-09-03
AU2002232616A1 (en) 2002-06-11
JP2004514686A (en) 2004-05-20
WO2002043666A2 (en) 2002-06-06

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