WO2002029073A3 - Gene delivery vectors for stem cells - Google Patents
Gene delivery vectors for stem cells Download PDFInfo
- Publication number
- WO2002029073A3 WO2002029073A3 PCT/NL2001/000731 NL0100731W WO0229073A3 WO 2002029073 A3 WO2002029073 A3 WO 2002029073A3 NL 0100731 W NL0100731 W NL 0100731W WO 0229073 A3 WO0229073 A3 WO 0229073A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- disease
- stem cells
- gene delivery
- tropism
- adenoviruses
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10344—Chimeric viral vector comprising heterologous viral elements for production of another viral vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10345—Special targeting system for viral vectors
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002211087A AU2002211087A1 (en) | 2000-10-06 | 2001-10-04 | Gene delivery vectors for stem cells |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23883000P | 2000-10-06 | 2000-10-06 | |
EP00203471.8 | 2000-10-06 | ||
US60/238,830 | 2000-10-06 | ||
EP00203471A EP1195440A1 (en) | 2000-10-06 | 2000-10-06 | Gene delivery vectors for stem cells |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002029073A2 WO2002029073A2 (en) | 2002-04-11 |
WO2002029073A3 true WO2002029073A3 (en) | 2002-10-03 |
Family
ID=26072760
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/NL2001/000731 WO2002029073A2 (en) | 2000-10-06 | 2001-10-04 | Gene delivery vectors for stem cells |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2002211087A1 (en) |
WO (1) | WO2002029073A2 (en) |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5911983A (en) * | 1992-06-26 | 1999-06-15 | University Of Pittsburgh | Gene therapy for Gaucher disease using retroviral vectors |
WO1999032647A1 (en) * | 1997-12-23 | 1999-07-01 | Introgene B.V. | Adeno-associated virus and adenovirus chimeric recombinant viruses useful for the integration of foreign genetic information into the chromosomal dna of target cells |
WO2000003029A2 (en) * | 1998-07-08 | 2000-01-20 | Introgene B.V. | Chimaeric adenoviruses |
WO2000052186A1 (en) * | 1999-03-04 | 2000-09-08 | Introgene B.V. | Means and methods for fibroblast-like or macrophage-like cell transduction |
WO2000070071A1 (en) * | 1999-05-17 | 2000-11-23 | Crucell Holland B.V. | Adenovirus derived gene delivery vehicles comprising at least one element of adenovirus type 35 |
WO2000073478A2 (en) * | 1999-06-01 | 2000-12-07 | University Of Washington | Recombinant adenoviral vectors expressing chimeric fiber proteins for cell specific infection and genome integration |
WO2002024933A2 (en) * | 2000-09-25 | 2002-03-28 | Galapagos Genomics N.V. | Viral vectors having tissue tropism for t-lymphocytes, b- and mast cells |
WO2002027006A1 (en) * | 2000-09-26 | 2002-04-04 | Crucell Holland B.V. | Adenoviral vectors for gene delivery in skeletal muscle cells or myoblasts |
-
2001
- 2001-10-04 AU AU2002211087A patent/AU2002211087A1/en not_active Abandoned
- 2001-10-04 WO PCT/NL2001/000731 patent/WO2002029073A2/en active Application Filing
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5911983A (en) * | 1992-06-26 | 1999-06-15 | University Of Pittsburgh | Gene therapy for Gaucher disease using retroviral vectors |
WO1999032647A1 (en) * | 1997-12-23 | 1999-07-01 | Introgene B.V. | Adeno-associated virus and adenovirus chimeric recombinant viruses useful for the integration of foreign genetic information into the chromosomal dna of target cells |
WO2000003029A2 (en) * | 1998-07-08 | 2000-01-20 | Introgene B.V. | Chimaeric adenoviruses |
WO2000052186A1 (en) * | 1999-03-04 | 2000-09-08 | Introgene B.V. | Means and methods for fibroblast-like or macrophage-like cell transduction |
WO2000070071A1 (en) * | 1999-05-17 | 2000-11-23 | Crucell Holland B.V. | Adenovirus derived gene delivery vehicles comprising at least one element of adenovirus type 35 |
WO2000073478A2 (en) * | 1999-06-01 | 2000-12-07 | University Of Washington | Recombinant adenoviral vectors expressing chimeric fiber proteins for cell specific infection and genome integration |
WO2002024933A2 (en) * | 2000-09-25 | 2002-03-28 | Galapagos Genomics N.V. | Viral vectors having tissue tropism for t-lymphocytes, b- and mast cells |
WO2002027006A1 (en) * | 2000-09-26 | 2002-04-04 | Crucell Holland B.V. | Adenoviral vectors for gene delivery in skeletal muscle cells or myoblasts |
Non-Patent Citations (5)
Title |
---|
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1994, BAHNSON ALFRED B ET AL: "Transduction of CD34+ enriched cord blood and Gaucher bone marrow cells by a retroviral vector carrying the glucocerebrosidase gene.", XP002163089, Database accession no. PREV199497497999 * |
GENE THERAPY, vol. 1, no. 3, 1994, pages 178 - 184 * |
LIEBER ANDRE ET AL: "Integrating adenovirus-adeno-associated virus hybrid vectors devoid of all viral genes.", JOURNAL OF VIROLOGY, vol. 73, no. 11, November 1999 (1999-11-01), pages 9314 - 9324, XP002163087, ISSN: 0022-538X * |
SHAYAKHMETOV D M ET AL: "EFFICIENT GENE TRANSFER INTO HUMAN CD34+ CELLS BY A RETARGETED ADENOVIRUS VECTOR", JOURNAL OF VIROLOGY,THE AMERICAN SOCIETY FOR MICROBIOLOGY,US, vol. 74, no. 6, March 2000 (2000-03-01), pages 2567 - 2583, XP000938716, ISSN: 0022-538X * |
VAN BEUSECHEM V W ET AL: "LONG-TERM EXPRESSION OF HUMAN ADENOSINE DEAMINASE IN RHESUS MONKEYS TRANSPLANTED WITH RETROVIRUS-INFECTED BONE-MARROW CELLS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 89, no. 16, 1992, 1992, pages 7640 - 7644, XP002163088, ISSN: 0027-8424 * |
Also Published As
Publication number | Publication date |
---|---|
AU2002211087A1 (en) | 2002-04-15 |
WO2002029073A2 (en) | 2002-04-11 |
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