WO2002027909A3 - Apparatus for switchng and manipulating particles and method of use thereof - Google Patents

Apparatus for switchng and manipulating particles and method of use thereof Download PDF

Info

Publication number
WO2002027909A3
WO2002027909A3 PCT/US2001/042426 US0142426W WO0227909A3 WO 2002027909 A3 WO2002027909 A3 WO 2002027909A3 US 0142426 W US0142426 W US 0142426W WO 0227909 A3 WO0227909 A3 WO 0227909A3
Authority
WO
WIPO (PCT)
Prior art keywords
branches
particles
switchng
traveling
branch
Prior art date
Application number
PCT/US2001/042426
Other languages
French (fr)
Other versions
WO2002027909A8 (en
WO2002027909A2 (en
Inventor
Xiao-Bo Wang
Weiping Yang
Junquan Xu
Jing Cheng
Lei Wu
Original Assignee
Aviva Biosciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CNB001290436A external-priority patent/CN1325909C/en
Application filed by Aviva Biosciences Corp filed Critical Aviva Biosciences Corp
Priority to EP01979923A priority Critical patent/EP1320922A2/en
Priority to CA002421939A priority patent/CA2421939A1/en
Priority to AU2002211838A priority patent/AU2002211838A1/en
Publication of WO2002027909A2 publication Critical patent/WO2002027909A2/en
Publication of WO2002027909A3 publication Critical patent/WO2002027909A3/en
Publication of WO2002027909A8 publication Critical patent/WO2002027909A8/en

Links

Classifications

    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02N—ELECTRIC MACHINES NOT OTHERWISE PROVIDED FOR
    • H02N1/00—Electrostatic generators or motors using a solid moving electrostatic charge carrier
    • H02N1/002—Electrostatic motors
    • H02N1/004—Electrostatic motors in which a body is moved along a path due to interaction with an electric field travelling along the path
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D57/00—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C
    • B01D57/02—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C by electrophoresis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/02—Separators
    • B03C5/022—Non-uniform field separators
    • B03C5/028—Non-uniform field separators using travelling electric fields, i.e. travelling wave dielectrophoresis [TWD]
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02N—ELECTRIC MACHINES NOT OTHERWISE PROVIDED FOR
    • H02N11/00—Generators or motors not provided for elsewhere; Alleged perpetua mobilia obtained by electric or magnetic means
    • H02N11/006—Motors

Abstract

A device (103, 106, 112, 113, 110, 152, 158, 168, 170A, 170B, 170C, 182, 184, 250, 295) acts as a particle switch to transport and/or re-direct microparticles which are in a fluid suspension. The switch (103, 107, 112, 113, 110, 152, 158, 168, 170A, 170B, 170C, 182, 184, 250, 295) comprises at least three structural branches (e.g., 103a/103b/103c, 107a/107b/107c/107d, 110a/110b/110c, 110d/110e/110f, 110g/110h/110i, 152a/152b/152c, etc.); and the branches may be connected at a common junction (103, 107, 150, 158, 258). Particles (160, 164) can be transported along the branches as a result of the forces generated along that branch. Particles are transported into or out of the particle switch via the ends (e.g., 105a, 105b, 105c, 108a, 108b, 108c) of the branches. Particles can be switched from one branch into one of the other branches. Depending on the properties of the particles, the transportation mechanism may be traveling-wave-dielectrophoresis or traveling-wave-electrophoresis.
PCT/US2001/042426 2000-09-27 2001-09-24 Apparatus for switchng and manipulating particles and method of use thereof WO2002027909A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP01979923A EP1320922A2 (en) 2000-09-27 2001-09-24 Apparatus for switchng and manipulating particles and method of use thereof
CA002421939A CA2421939A1 (en) 2000-09-27 2001-09-24 Apparatus for switchng and manipulating particles and method of use thereof
AU2002211838A AU2002211838A1 (en) 2000-09-27 2001-09-24 Apparatus for switchng and manipulating particles and method of use thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN00129043.6 2000-09-27
CNB001290436A CN1325909C (en) 2000-09-27 2000-09-27 Apparatus for particle operation and guide and use method thereof
US09/678,263 2000-10-03
US09/678,263 US6596143B1 (en) 2000-09-27 2000-10-03 Apparatus for switching and manipulating particles and method of use thereof

Publications (3)

Publication Number Publication Date
WO2002027909A2 WO2002027909A2 (en) 2002-04-04
WO2002027909A3 true WO2002027909A3 (en) 2002-07-25
WO2002027909A8 WO2002027909A8 (en) 2003-11-20

Family

ID=25739591

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/042426 WO2002027909A2 (en) 2000-09-27 2001-09-24 Apparatus for switchng and manipulating particles and method of use thereof

Country Status (4)

Country Link
EP (1) EP1320922A2 (en)
AU (1) AU2002211838A1 (en)
CA (1) CA2421939A1 (en)
WO (1) WO2002027909A2 (en)

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US7015047B2 (en) 2001-01-26 2006-03-21 Aviva Biosciences Corporation Microdevices having a preferential axis of magnetization and uses thereof
US7811768B2 (en) 2001-01-26 2010-10-12 Aviva Biosciences Corporation Microdevice containing photorecognizable coding patterns and methods of using and producing the same
CN100494360C (en) 2001-03-22 2009-06-03 博奥生物有限公司 Process for separating cells and its application
US20060029955A1 (en) 2001-03-24 2006-02-09 Antonio Guia High-density ion transport measurement biochip devices and methods
CA2441366A1 (en) 2001-03-24 2002-10-03 Aviva Biosciences Corporation Biochips including ion transport detecting structures and methods of use
US8986944B2 (en) 2001-10-11 2015-03-24 Aviva Biosciences Corporation Methods and compositions for separating rare cells from fluid samples
US8980568B2 (en) 2001-10-11 2015-03-17 Aviva Biosciences Corporation Methods and compositions for detecting non-hematopoietic cells from a blood sample
EP1501924A4 (en) 2002-05-04 2006-05-24 Aviva Biosciences Corp Apparatus including ion transport detecting structures and methods of use
GB2392977A (en) * 2002-09-13 2004-03-17 Suisse Electronique Microtech A fluidic dielectrophoretic system and method for analysing biomolecules
US7105081B2 (en) * 2002-12-20 2006-09-12 Board Of Regents, The University Of Texas System Methods and apparatus for electrosmear analysis
US7156970B2 (en) 2003-06-12 2007-01-02 Palo Alto Research Center Incorporated Distributed multi-segmented reconfigurable traveling wave grids for separation of proteins in gel electrophoresis
US7309410B2 (en) * 2003-12-03 2007-12-18 Palo Alto Research Center Incorporated Traveling wave grids and algorithms for biomolecule separation, transport and focusing
CA2657621A1 (en) 2006-07-14 2008-01-17 Aviva Biosciences Corporation Methods and compositions for detecting rare cells from a biological sample
US9399217B2 (en) 2010-10-04 2016-07-26 Genapsys, Inc. Chamber free nanoreactor system
US9184099B2 (en) 2010-10-04 2015-11-10 The Board Of Trustees Of The Leland Stanford Junior University Biosensor devices, systems and methods therefor
EP2625526B1 (en) 2010-10-04 2017-03-15 Genapsys Inc. Systems and methods for automated reusable parallel biological reactions
US9926596B2 (en) 2011-05-27 2018-03-27 Genapsys, Inc. Systems and methods for genetic and biological analysis
US8585973B2 (en) 2011-05-27 2013-11-19 The Board Of Trustees Of The Leland Stanford Junior University Nano-sensor array
EP2785868B1 (en) 2011-12-01 2017-04-12 Genapsys Inc. Systems and methods for high efficiency electronic sequencing and detection
WO2013104994A2 (en) * 2012-01-13 2013-07-18 The University Of British Columbia Multiple arm apparatus and methods for separation of particles
US9809852B2 (en) 2013-03-15 2017-11-07 Genapsys, Inc. Systems and methods for biological analysis
WO2015089238A1 (en) 2013-12-11 2015-06-18 Genapsys, Inc. Systems and methods for biological analysis and computation
EP3556864B1 (en) 2014-04-18 2020-12-09 Genapsys, Inc. Methods and systems for nucleic acid amplification
US10544456B2 (en) 2016-07-20 2020-01-28 Genapsys, Inc. Systems and methods for nucleic acid sequencing
SG11202002516WA (en) 2017-09-21 2020-04-29 Genapsys Inc Systems and methods for nucleic acid sequencing

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19544127C1 (en) * 1995-11-27 1997-03-20 Gimsa Jan Dr Suspended particle micro-manipulation
DE19653659C1 (en) * 1996-12-20 1998-05-20 Guenter Prof Dr Fuhr Electrode arrangement for field cages

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19544127C1 (en) * 1995-11-27 1997-03-20 Gimsa Jan Dr Suspended particle micro-manipulation
DE19653659C1 (en) * 1996-12-20 1998-05-20 Guenter Prof Dr Fuhr Electrode arrangement for field cages

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MASUDA S ET AL: "SEPARATION OF SMALL PARTICLES SUSPENDED IN LIQUID BY NONUNIFORM TRAVELING FIELD", IEEE TRANSACTIONS ON INDUSTRY APPLICATIONS, IEEE INC. NEW YORK, US, vol. IA 23, no. 3, 1 May 1987 (1987-05-01), pages 474 - 480, XP000570706, ISSN: 0093-9994 *

Also Published As

Publication number Publication date
EP1320922A2 (en) 2003-06-25
AU2002211838A1 (en) 2002-04-08
CA2421939A1 (en) 2002-04-04
WO2002027909A8 (en) 2003-11-20
WO2002027909A2 (en) 2002-04-04

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