WO2002022136A1 - Diphosphonate solutions - Google Patents
Diphosphonate solutions Download PDFInfo
- Publication number
- WO2002022136A1 WO2002022136A1 PCT/AU2001/001171 AU0101171W WO0222136A1 WO 2002022136 A1 WO2002022136 A1 WO 2002022136A1 AU 0101171 W AU0101171 W AU 0101171W WO 0222136 A1 WO0222136 A1 WO 0222136A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- solution
- pharmaceutical product
- product according
- glass
- polymer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Abstract
Description
Claims
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/380,645 US20040082545A1 (en) | 2000-09-18 | 2001-09-18 | Diphosphonate solutions |
CA002406446A CA2406446A1 (en) | 2000-09-18 | 2001-09-18 | Diphosphonate solutions |
KR10-2003-7002186A KR20030043931A (en) | 2000-09-18 | 2001-09-18 | Diphosphonate solutions |
EP01973807A EP1318818A4 (en) | 2000-09-18 | 2001-09-18 | Diphosphonate solutions |
AU2001293473A AU2001293473A1 (en) | 2000-09-18 | 2001-09-18 | Diphosphonate solutions |
NO20031215A NO20031215L (en) | 2000-09-18 | 2003-03-17 | Difosfonatlösninger |
US11/190,493 US20060154900A1 (en) | 2000-09-18 | 2005-07-26 | Diphosphonate solutions |
US11/194,106 US20060154898A1 (en) | 2000-09-18 | 2005-07-28 | Diphosphonate solutions |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPR0189 | 2000-02-18 | ||
AUPR0189A AUPR018900A0 (en) | 2000-09-18 | 2000-09-18 | Pamidronate solution |
AUPR4855A AUPR485501A0 (en) | 2001-05-10 | 2001-05-10 | Stable injectable solutions |
AUPR4855 | 2001-05-10 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/190,493 Continuation US20060154900A1 (en) | 2000-09-18 | 2005-07-26 | Diphosphonate solutions |
US11/194,106 Continuation US20060154898A1 (en) | 2000-09-18 | 2005-07-28 | Diphosphonate solutions |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2002022136A1 true WO2002022136A1 (en) | 2002-03-21 |
Family
ID=25646444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/AU2001/001171 WO2002022136A1 (en) | 2000-09-18 | 2001-09-18 | Diphosphonate solutions |
Country Status (10)
Country | Link |
---|---|
US (3) | US20040082545A1 (en) |
EP (2) | EP1671638A1 (en) |
KR (1) | KR20030043931A (en) |
CN (1) | CN1441674A (en) |
AU (1) | AU2001293473A1 (en) |
CA (1) | CA2406446A1 (en) |
NO (1) | NO20031215L (en) |
PL (1) | PL360910A1 (en) |
TW (1) | TW200418494A (en) |
WO (1) | WO2002022136A1 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005025551A3 (en) * | 2003-09-18 | 2006-01-12 | Novartis Ag | Pharmaceutical products comprising bisphosphonates |
EP2363111A1 (en) * | 2010-03-01 | 2011-09-07 | Combino Pharm, S.L. | Stable pharmaceutical composition comprising bisphosphonate |
WO2011107646A1 (en) * | 2010-03-05 | 2011-09-09 | Capital, Business Y Gestión De Finanzas, S.L. | Pharmaceutical composition |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006100687A1 (en) * | 2005-03-24 | 2006-09-28 | Dabur Pharma Ltd. | Disodium pamidronate aqueous formulation |
US7605148B2 (en) * | 2007-04-16 | 2009-10-20 | Aurobindo Pharma Ltd. | Aqueous oral solution of bisphosphonic acid |
WO2011127629A1 (en) * | 2010-04-16 | 2011-10-20 | 台湾东洋药品工业股份有限公司 | Pharmaceutical product of diphosphonate injection and preparation method thereof |
CN116077446A (en) * | 2022-12-16 | 2023-05-09 | 上药东英(江苏)药业有限公司 | Rabeprazole sodium freeze-dried powder injection and preparation method thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5219556A (en) * | 1990-07-09 | 1993-06-15 | Mallinckrodt Medical, Inc. | Stabilized therapeutic radiopharmaceutical complexes |
US5914323A (en) * | 1994-08-24 | 1999-06-22 | Merck & Co., Inc. | Intravenous alendronate formulations |
WO2000034293A1 (en) * | 1998-12-10 | 2000-06-15 | Aesgen, Inc. | Method for preparation of disodium pamidronate |
DE20106394U1 (en) * | 2001-04-11 | 2001-08-09 | Helm Pharmaceuticals Gmbh | Pharmaceutical preparation |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE7612534L (en) * | 1975-12-01 | 1977-06-02 | Henkel & Cie Gmbh | PROCEDURE FOR THE PREPARATION OF PHARMACEUTICALS FOR THE TREATMENT OF CALCIUM SUBSTANCE DEFICIENCIES |
US4304734A (en) * | 1980-10-16 | 1981-12-08 | Vysoka Skola Chemicko-Technologicka | 6-Amino-1-hydroxyhexylidene diphosphonic acid, salts and a process for production thereof |
US4639338A (en) * | 1984-08-06 | 1987-01-27 | Ciba-Geigy Corporation | Preparation of crystalline disodium 3-amino-1-hydroxypropane-1,1-diphosphonate pentahydrate |
US5167816A (en) * | 1990-08-20 | 1992-12-01 | Abbott Laboratories | Sterile coupling device for drug container |
DE4228552A1 (en) * | 1992-08-27 | 1994-03-03 | Boehringer Mannheim Gmbh | Drugs containing diphosphonic acids and their salts |
JP3672342B2 (en) * | 1994-09-26 | 2005-07-20 | アステラス製薬株式会社 | Injection solution containing bisphosphonic acid or derivative thereof, stabilization method thereof, and injection solution ampoule |
US5853894A (en) * | 1997-02-03 | 1998-12-29 | Cytonix Corporation | Laboratory vessel having hydrophobic coating and process for manufacturing same |
US6087350A (en) * | 1997-08-29 | 2000-07-11 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Use of pretreatment chemicals to enhance efficacy of cytotoxic agents |
US6174873B1 (en) * | 1998-11-04 | 2001-01-16 | Supergen, Inc. | Oral administration of adenosine analogs |
US6794536B1 (en) * | 1998-12-10 | 2004-09-21 | Aesqen, Inc. | Method for preparation of disodium pamidronate |
US6160165A (en) * | 1998-12-10 | 2000-12-12 | Aesgen, Inc. | Method for preparation of disodium pamidronate |
US6309596B1 (en) * | 1998-12-15 | 2001-10-30 | Bausch & Lomb Incorporated | Treatment of contact lenses with aqueous solution comprising a biguanide disinfectant stabilized by a poloxamine |
US6167369A (en) * | 1998-12-23 | 2000-12-26 | Xerox Company | Automatic language identification using both N-gram and word information |
EP1189603A2 (en) * | 1999-03-22 | 2002-03-27 | Immugen Pharmaceuticals, Inc. | Treatment of immune diseases like hiv disease and neoplastic disorders |
US6211169B1 (en) * | 1999-09-29 | 2001-04-03 | Aesgen, Inc. | Stable calcitriol solution for packaging into vials |
EP1136069A1 (en) * | 2000-03-21 | 2001-09-26 | SPA SOCIETA' PRODOTTI ANTIBIOTICI S.p.A. | Pharmaceutical compositions containing clodronates for high local tolerance intramuscular administration |
WO2002087592A1 (en) * | 2001-05-02 | 2002-11-07 | Sicor Inc. | Injectable pamidronate disodium |
-
2001
- 2001-09-18 CA CA002406446A patent/CA2406446A1/en not_active Abandoned
- 2001-09-18 WO PCT/AU2001/001171 patent/WO2002022136A1/en not_active Application Discontinuation
- 2001-09-18 CN CN01812743A patent/CN1441674A/en active Pending
- 2001-09-18 EP EP06007027A patent/EP1671638A1/en not_active Withdrawn
- 2001-09-18 KR KR10-2003-7002186A patent/KR20030043931A/en not_active Application Discontinuation
- 2001-09-18 AU AU2001293473A patent/AU2001293473A1/en not_active Abandoned
- 2001-09-18 PL PL36091001A patent/PL360910A1/en not_active Application Discontinuation
- 2001-09-18 US US10/380,645 patent/US20040082545A1/en not_active Abandoned
- 2001-09-18 EP EP01973807A patent/EP1318818A4/en not_active Withdrawn
- 2001-09-19 TW TW093111927A patent/TW200418494A/en unknown
-
2003
- 2003-03-17 NO NO20031215A patent/NO20031215L/en not_active Application Discontinuation
-
2005
- 2005-07-26 US US11/190,493 patent/US20060154900A1/en not_active Abandoned
- 2005-07-28 US US11/194,106 patent/US20060154898A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5219556A (en) * | 1990-07-09 | 1993-06-15 | Mallinckrodt Medical, Inc. | Stabilized therapeutic radiopharmaceutical complexes |
US5914323A (en) * | 1994-08-24 | 1999-06-22 | Merck & Co., Inc. | Intravenous alendronate formulations |
WO2000034293A1 (en) * | 1998-12-10 | 2000-06-15 | Aesgen, Inc. | Method for preparation of disodium pamidronate |
DE20106394U1 (en) * | 2001-04-11 | 2001-08-09 | Helm Pharmaceuticals Gmbh | Pharmaceutical preparation |
Non-Patent Citations (2)
Title |
---|
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 135:216036, HELM PHARMACEUTICALS GMBH XP008049806 * |
See also references of EP1318818A4 * |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005025551A3 (en) * | 2003-09-18 | 2006-01-12 | Novartis Ag | Pharmaceutical products comprising bisphosphonates |
JP2007505861A (en) * | 2003-09-18 | 2007-03-15 | ノバルティス アクチエンゲゼルシャフト | Pharmaceutical products containing bisphosphonates |
KR101015718B1 (en) * | 2003-09-18 | 2011-02-22 | 노파르티스 아게 | Pharmaceutical products comprising bisphosphonates |
US7932241B2 (en) | 2003-09-18 | 2011-04-26 | Novartis Ag | Pharmaceutical products comprising bisphosphonates |
JP4802096B2 (en) * | 2003-09-18 | 2011-10-26 | ノバルティス アーゲー | Pharmaceutical products containing bisphosphonates |
EP2363111A1 (en) * | 2010-03-01 | 2011-09-07 | Combino Pharm, S.L. | Stable pharmaceutical composition comprising bisphosphonate |
WO2011107408A1 (en) * | 2010-03-01 | 2011-09-09 | Combino Pharm, S.L. | Stable pharmaceutical composition comprising bisphosphonate |
WO2011107646A1 (en) * | 2010-03-05 | 2011-09-09 | Capital, Business Y Gestión De Finanzas, S.L. | Pharmaceutical composition |
Also Published As
Publication number | Publication date |
---|---|
CA2406446A1 (en) | 2002-03-21 |
NO20031215D0 (en) | 2003-03-17 |
TW200418494A (en) | 2004-10-01 |
US20060154898A1 (en) | 2006-07-13 |
PL360910A1 (en) | 2004-09-20 |
CN1441674A (en) | 2003-09-10 |
EP1318818A1 (en) | 2003-06-18 |
EP1671638A1 (en) | 2006-06-21 |
AU2001293473A1 (en) | 2002-03-26 |
US20060154900A1 (en) | 2006-07-13 |
EP1318818A4 (en) | 2004-09-29 |
US20040082545A1 (en) | 2004-04-29 |
NO20031215L (en) | 2003-05-16 |
KR20030043931A (en) | 2003-06-02 |
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