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WO2002012888A3 - Capsules encapsulating solid particles of signal-generating organic substances - Google Patents

Capsules encapsulating solid particles of signal-generating organic substances

Info

Publication number
WO2002012888A3
WO2002012888A3 PCT/EP2001/009114 EP0109114W WO2002012888A3 WO 2002012888 A3 WO2002012888 A3 WO 2002012888A3 EP 0109114 W EP0109114 W EP 0109114W WO 2002012888 A3 WO2002012888 A3 WO 2002012888A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
signal
capsules
generating
organic
molecules
Prior art date
Application number
PCT/EP2001/009114
Other languages
French (fr)
Other versions
WO2002012888A2 (en )
Inventor
Dieter Trau
Reinhard Renneberg
Frank Caruso
Matthias Lehmann
Original Assignee
8Sens Biognostic Ag
Dieter Trau
Reinhard Renneberg
Frank Caruso
Matthias Lehmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587Nanoparticles

Abstract

The present invention refers to capsules encapsulating solid particles of signal-generating organic substances and carrying on the outer surface affinity molecules for secific recognition of and binding to target molecules in a sample. The invention is directed to teh use of these capsules for signal production in the optical, electrochemical or chemical detection of target molecules. To obtain a signal the signal-generating organic substances are released and dissolved. A detection method and a kit are provided.
PCT/EP2001/009114 2000-08-08 2001-08-07 Capsules encapsulating solid particles of signal-generating organic substances WO2002012888A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE10042023.0 2000-08-08
DE2000142023 DE10042023C2 (en) 2000-08-08 2000-08-08 Capsules encapsulating solid particles of signal-generating organic substances, and their use in bioassays for detection of target molecules in a sample

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10344016 US20040014073A1 (en) 2000-08-08 2001-08-07 Capsules encapsulating solid particles of signal-generating organic substances and their use in vitro bioassays for detection of target molecules in a sample
DE2001623806 DE60123806D1 (en) 2000-08-08 2001-08-07 Capsules containing solid particles of signal-generating organic substances
CA 2417714 CA2417714A1 (en) 2000-08-08 2001-08-07 Capsules encapsulating solid particles of signal-generating organic substances
EP20010971884 EP1309867B1 (en) 2000-08-08 2001-08-07 Capsules encapsulating solid particles of signal-generating organic substances

Publications (2)

Publication Number Publication Date
WO2002012888A2 true WO2002012888A2 (en) 2002-02-14
WO2002012888A3 true true WO2002012888A3 (en) 2002-05-16

Family

ID=7653916

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/009114 WO2002012888A3 (en) 2000-08-08 2001-08-07 Capsules encapsulating solid particles of signal-generating organic substances

Country Status (5)

Country Link
US (1) US20040014073A1 (en)
EP (1) EP1309867B1 (en)
CA (1) CA2417714A1 (en)
DE (2) DE10042023C2 (en)
WO (1) WO2002012888A3 (en)

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US8691594B2 (en) 1996-04-25 2014-04-08 Bioarray Solutions, Ltd. Method of making a microbead array with attached biomolecules
US9147037B2 (en) 2004-08-02 2015-09-29 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
US9251583B2 (en) 2002-11-15 2016-02-02 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
US9436088B2 (en) 2001-06-21 2016-09-06 Bioarray Solutions, Ltd. Un-supported polymeric film with embedded microbeads

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US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7312040B2 (en) * 2002-09-20 2007-12-25 Agilent Technologies, Inc. Microcapsule biosensors and methods of using the same
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US7247500B2 (en) * 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
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US20040197819A1 (en) * 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7927796B2 (en) * 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
CA2899287A1 (en) 2003-10-28 2005-05-12 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
WO2005045059A3 (en) * 2003-10-28 2005-09-09 Bioarray Solutions Ltd Allele assignment and probe selection in multiplexed assays of polymorphic targets
CA2544262A1 (en) * 2003-10-28 2005-05-12 Bioarray Solutions Ltd. Gel-shell beads with adsorbed or bound biomolecules
ES2533876T3 (en) 2003-10-29 2015-04-15 Bioarray Solutions Ltd Multiplexed analysis of nucleic acids by fragmentation dsDNA
US20050112703A1 (en) 2003-11-21 2005-05-26 Kimberly-Clark Worldwide, Inc. Membrane-based lateral flow assay devices that utilize phosphorescent detection
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US7943395B2 (en) * 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
US7094528B2 (en) * 2004-06-30 2006-08-22 Kimberly-Clark Worldwide, Inc. Magnetic enzyme detection techniques
US7906276B2 (en) 2004-06-30 2011-03-15 Kimberly-Clark Worldwide, Inc. Enzymatic detection techniques
US7363170B2 (en) * 2004-07-09 2008-04-22 Bio Array Solutions Ltd. Transfusion registry network providing real-time interaction between users and providers of genetically characterized blood products
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
DK1957050T3 (en) * 2005-11-14 2014-01-20 Louisiana Tech University Res Foundation Polypeptidfilm and Methods
US8183184B2 (en) * 2006-09-05 2012-05-22 University Of Kansas Polyelectrolyte complexes for oil and gas applications
WO2008157372A3 (en) 2007-06-14 2009-12-30 Massachusetts Institute Of Technology Self assembled films for protein and drug delivery applications
US8530244B2 (en) * 2007-10-02 2013-09-10 Terapia Celular, L'N, Inc. Methods and materials for amplification of a signal in an immunoassay
JP2011508233A (en) * 2007-12-27 2011-03-10 インフィゴ ダイアグノスティクス リミテッドInfigo Diagnostics Ltd. Small molecules and protein analysis devices based on molecularly imprinted polymers
DE102008019928A1 (en) * 2008-04-21 2009-12-31 Siemens Healthcare Diagnostics Gmbh Procedures for applying spots with capture molecules on substrate surface for chip, particularly optical sensor, involve washing substrate surface of chip by dipping in aqueous solution of cationic polyelectrolyte
US8383337B2 (en) 2008-07-18 2013-02-26 General Electric Company Methods using metal oxide particles for analyte detection
GB0910010D0 (en) * 2009-06-10 2009-07-22 Dna Supernova Ltd Signal amplification microspheres their use in one-step and multi-step analytical amplification procedures and methods for their production
GB0910203D0 (en) 2009-06-12 2009-07-29 Dna Supernova Ltd Signal accumulation for improvement of signal readability on solid phase substrates after signal amplification
FR2965273B1 (en) * 2010-09-29 2015-07-17 Centre Nat Rech Scient Method of preparing a chemical structure having partitioned capable of generating a fluorescence spectrum and its specific applications
US8586387B2 (en) * 2011-08-30 2013-11-19 Supernova Diagnostics, Inc. Methods of triggering activation of encapsulated signal-generating substances and apparatus utilising activated signal-generating substances
US20130052748A1 (en) 2011-08-30 2013-02-28 Supernova Diagnostics, Inc. Assay device and method of assaying
EP2617759B1 (en) * 2012-01-19 2014-12-03 Acreo Swedish ICT AB Method of modifying the properties of a surface
JP5996234B2 (en) * 2012-03-30 2016-09-21 デンカ生研株式会社 Immunoassay methods and reagents
CN102706929B (en) * 2012-05-10 2017-09-01 江南大学 A process for preparing a modified hyaluronic acid with molecular imprinting sensor photocrosslinkable
DE102013002575A1 (en) * 2013-02-11 2014-08-14 Max Renneberg A method of visualized exclusion of acute disorders by means of color-labeled proteins
CN104049079B (en) * 2013-03-14 2016-05-18 苏州德沃生物技术有限公司 A directional marker from an immune preparation method and application nanospheres
US9463244B2 (en) 2013-03-15 2016-10-11 Massachusetts Institute Of Technology Compositions and methods for nucleic acid delivery
WO2015048315A1 (en) * 2013-09-25 2015-04-02 Massachusetts Institute Of Technology Biodegradable layer-by-layer (lbl) films for cell capture and release
US20160047816A1 (en) * 2014-07-25 2016-02-18 SeLux Diagnostics, Inc. Assay methods involving dissociable nanoparticles
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WO2017015145A3 (en) * 2015-07-17 2017-03-09 SeLux Diagnostics, Inc. Dissociable nanoparticles with inter alia transition-metal complex catalysts

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8691594B2 (en) 1996-04-25 2014-04-08 Bioarray Solutions, Ltd. Method of making a microbead array with attached biomolecules
US9400259B2 (en) 1996-04-25 2016-07-26 Bioarray Solutions, Ltd. Method of making a microbead array with attached biomolecules
US9436088B2 (en) 2001-06-21 2016-09-06 Bioarray Solutions, Ltd. Un-supported polymeric film with embedded microbeads
US9251583B2 (en) 2002-11-15 2016-02-02 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
US8691754B2 (en) 2003-09-22 2014-04-08 Bioarray Solutions, Ltd. Microparticles with enhanced covalent binding capacity and their uses
US9147037B2 (en) 2004-08-02 2015-09-29 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification

Also Published As

Publication number Publication date Type
DE60123806D1 (en) 2006-11-23 grant
WO2002012888A2 (en) 2002-02-14 application
DE10042023C2 (en) 2003-04-10 grant
US20040014073A1 (en) 2004-01-22 application
CA2417714A1 (en) 2002-02-14 application
DE10042023A1 (en) 2002-02-28 application
EP1309867B1 (en) 2006-10-11 grant
EP1309867A2 (en) 2003-05-14 application

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