WO2002002599A3 - Recepteur couple aux proteines g humaines igpcr17, et son utilisation - Google Patents

Recepteur couple aux proteines g humaines igpcr17, et son utilisation Download PDF

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Publication number
WO2002002599A3
WO2002002599A3 PCT/EP2001/007532 EP0107532W WO0202599A3 WO 2002002599 A3 WO2002002599 A3 WO 2002002599A3 EP 0107532 W EP0107532 W EP 0107532W WO 0202599 A3 WO0202599 A3 WO 0202599A3
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WO
WIPO (PCT)
Prior art keywords
igpcr17
protein
coupled receptor
receptor
human
Prior art date
Application number
PCT/EP2001/007532
Other languages
English (en)
Other versions
WO2002002599A2 (fr
Inventor
Frank Wattler
Sigrid Wattler
Paul Trommler
Michael C Nehls
Original Assignee
Ingenium Pharmaceuticals Ag
Frank Wattler
Sigrid Wattler
Paul Trommler
Michael C Nehls
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ingenium Pharmaceuticals Ag, Frank Wattler, Sigrid Wattler, Paul Trommler, Michael C Nehls filed Critical Ingenium Pharmaceuticals Ag
Priority to AU2001281933A priority Critical patent/AU2001281933A1/en
Publication of WO2002002599A2 publication Critical patent/WO2002002599A2/fr
Publication of WO2002002599A3 publication Critical patent/WO2002002599A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Selon l'invention, une nouvelle protéine de récepteur couplée aux protéines G humaines (GPcR), IGPcR17, a été identifiée et caractérisée. L'invention concerne également des nucléotides codant le IGPcR17, des protéines de IGPcR17 et des protéines de fusion, des anticorps dirigés contre le récepteur, des systèmes d'expression de cellules hôtes, des modèles animaux dans lesquels le gène IGPcR17 subit une mutation, des animaux 'knock-out' de recombinaison qui n'expriment pas le IGPcR17, et des animaux transgéniques qui expriment un transgène de IGPcR17, ainsi que des composés qui modulent l'expression génique ou l'activité de récepteur du IGPcR17 et leur utilisation pour la sélection de médicaments, et pour le diagnostic ou le traitement de maladies, en particulier de troubles du système nerveux central.
PCT/EP2001/007532 2000-06-30 2001-07-02 Recepteur couple aux proteines g humaines igpcr17, et son utilisation WO2002002599A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001281933A AU2001281933A1 (en) 2000-06-30 2001-07-02 Human g protein-coupled receptor igpcr17, and uses therof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21575900P 2000-06-30 2000-06-30
US60/215,759 2000-06-30

Publications (2)

Publication Number Publication Date
WO2002002599A2 WO2002002599A2 (fr) 2002-01-10
WO2002002599A3 true WO2002002599A3 (fr) 2002-10-10

Family

ID=22804265

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/007532 WO2002002599A2 (fr) 2000-06-30 2001-07-02 Recepteur couple aux proteines g humaines igpcr17, et son utilisation

Country Status (2)

Country Link
AU (1) AU2001281933A1 (fr)
WO (1) WO2002002599A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6762029B2 (en) 1999-12-23 2004-07-13 Portola Pharmaceuticals, Inc. Methods of identifying agents that modulate P2Y12 receptor activity
ES2890882T3 (es) 2002-10-16 2022-01-24 Gen Probe Inc Composiciones y procedimientos para detectar el virus del Nilo occidental
US7927840B2 (en) 2006-09-11 2011-04-19 Gen Probe Incorporated Method for detecting West Nile Virus nucleic acids in the 3′ non-coding region

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998050549A2 (fr) * 1997-05-07 1998-11-12 Human Genome Sciences, Inc. Deux recepteurs couples par des proteines g: gpcr2 induit par veb (ebi-2) et gpcr de type gde-1
WO2000022131A2 (fr) * 1998-10-13 2000-04-20 Arena Pharmaceuticals, Inc. Recepteurs non-endogenes de la proteine g humaine ayant une activite constitutive
WO2000028028A1 (fr) * 1998-11-06 2000-05-18 Millennium Pharmaceuticals, Inc. Recepteurs a couplage de proteine g, homologues de gpcr 2 induits par ebv (ebi-2), et procedes permettant de rechercher certains de leurs ligands
WO2000031258A2 (fr) * 1998-11-20 2000-06-02 Arena Pharmaceuticals, Inc. Recepteurs humains couples a la proteine g orphan
WO2000034333A1 (fr) * 1998-12-10 2000-06-15 Astrazeneca Ab Nouveau recepteur couple aux proteines g
WO2001046454A1 (fr) * 1999-12-23 2001-06-28 Cor Therapeutics, Inc. Recepteur p2y12
WO2001057190A2 (fr) * 2000-02-03 2001-08-09 Hyseq, Inc. Acides nucleiques et polypeptides
WO2001085791A1 (fr) * 2000-05-11 2001-11-15 Lifespan Biosciences, Inc. Sequences d'acide nucleique destinees a de nouveaux gpcrs
WO2001098508A2 (fr) * 2000-06-21 2001-12-27 Deltagen, Inc. Souris transgeniques contenant des disruptions geniques ciblees
WO2002024942A2 (fr) * 2000-09-20 2002-03-28 The Regents Of The University Of California Recepteur d'adp-glucose

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998050549A2 (fr) * 1997-05-07 1998-11-12 Human Genome Sciences, Inc. Deux recepteurs couples par des proteines g: gpcr2 induit par veb (ebi-2) et gpcr de type gde-1
WO2000022131A2 (fr) * 1998-10-13 2000-04-20 Arena Pharmaceuticals, Inc. Recepteurs non-endogenes de la proteine g humaine ayant une activite constitutive
WO2000028028A1 (fr) * 1998-11-06 2000-05-18 Millennium Pharmaceuticals, Inc. Recepteurs a couplage de proteine g, homologues de gpcr 2 induits par ebv (ebi-2), et procedes permettant de rechercher certains de leurs ligands
WO2000031258A2 (fr) * 1998-11-20 2000-06-02 Arena Pharmaceuticals, Inc. Recepteurs humains couples a la proteine g orphan
WO2000034333A1 (fr) * 1998-12-10 2000-06-15 Astrazeneca Ab Nouveau recepteur couple aux proteines g
WO2001046454A1 (fr) * 1999-12-23 2001-06-28 Cor Therapeutics, Inc. Recepteur p2y12
WO2001057190A2 (fr) * 2000-02-03 2001-08-09 Hyseq, Inc. Acides nucleiques et polypeptides
WO2001085791A1 (fr) * 2000-05-11 2001-11-15 Lifespan Biosciences, Inc. Sequences d'acide nucleique destinees a de nouveaux gpcrs
WO2001098508A2 (fr) * 2000-06-21 2001-12-27 Deltagen, Inc. Souris transgeniques contenant des disruptions geniques ciblees
WO2002024942A2 (fr) * 2000-09-20 2002-03-28 The Regents Of The University Of California Recepteur d'adp-glucose

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 14 June 2001 (2001-06-14), TAKASAKI J. ET AL.: "Homo sapiens mRNA for Gi-coupled ADP receptor HORK3", XP002208266, Database accession no. AB052684 *
DATABASE EMBL 6 March 2000 (2000-03-06), MUZNY D. ET AL.: "Homo sapiens 3 BAC RP11-25K24", XP002208265, Database accession no. AC024886 *
DATABASE EMBL 6 November 2001 (2001-11-06), TANG Y. ET AL.: "Human polynucleotide SEQ ID NO: 927", XP002208267, Database accession no. AAK52382 *
DATABASE EMBL 6 November 2001 (2001-11-06), TANG Y. ET AL.: "Human protein SEQ ID NO: 1911", XP002208268, Database accession no. AAM79249 *

Also Published As

Publication number Publication date
WO2002002599A2 (fr) 2002-01-10
AU2001281933A1 (en) 2002-01-14

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