WO2001098784A3 - Particles and their use in molecular imprinting - Google Patents

Particles and their use in molecular imprinting Download PDF

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Publication number
WO2001098784A3
WO2001098784A3 PCT/GB2001/002794 GB0102794W WO0198784A3 WO 2001098784 A3 WO2001098784 A3 WO 2001098784A3 GB 0102794 W GB0102794 W GB 0102794W WO 0198784 A3 WO0198784 A3 WO 0198784A3
Authority
WO
WIPO (PCT)
Prior art keywords
particles
molecular imprinting
cavities
molecule
imprint
Prior art date
Application number
PCT/GB2001/002794
Other languages
French (fr)
Other versions
WO2001098784A2 (en
Inventor
Steven Robert Carter
Steven Rimmer
Original Assignee
Prometic Biosciences Ltd
Steven Robert Carter
Steven Rimmer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prometic Biosciences Ltd, Steven Robert Carter, Steven Rimmer filed Critical Prometic Biosciences Ltd
Priority to AT01940836T priority Critical patent/ATE279725T1/en
Priority to CA002412827A priority patent/CA2412827A1/en
Priority to DE60106442T priority patent/DE60106442T2/en
Priority to DK01940836T priority patent/DK1292828T3/en
Priority to EP01940836A priority patent/EP1292828B1/en
Priority to AU2001274329A priority patent/AU2001274329A1/en
Publication of WO2001098784A2 publication Critical patent/WO2001098784A2/en
Publication of WO2001098784A3 publication Critical patent/WO2001098784A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/268—Polymers created by use of a template, e.g. molecularly imprinted polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016—Particle form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/305—Addition of material, later completely removed, e.g. as result of heat treatment, leaching or washing, e.g. for forming pores
    • B01J20/3057—Use of a templating or imprinting material ; filling pores of a substrate or matrix followed by the removal of the substrate or matrix
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
    • B01J20/3293—Coatings on a core, the core being particle or fiber shaped, e.g. encapsulated particles, coated fibers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2600/00—Assays involving molecular imprinted polymers/polymers created around a molecular template

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Thermal Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Light Receiving Elements (AREA)
  • Solid State Image Pick-Up Elements (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

Particles capable of specific binding to an imprint molecule, comprises an outer shell including cavities that correspond to the imprint molecule, and an inner core substantially free of such cavities. Such particles can be used as a medium for various techniques, including separation of a target molecule.
PCT/GB2001/002794 2000-06-23 2001-06-22 Particles and their use in molecular imprinting WO2001098784A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AT01940836T ATE279725T1 (en) 2000-06-23 2001-06-22 PARTICLES AND THEIR USE IN MOLECULAR IMBOINTING
CA002412827A CA2412827A1 (en) 2000-06-23 2001-06-22 Particles and their use in molecular imprinting
DE60106442T DE60106442T2 (en) 2000-06-23 2001-06-22 PARTICLES AND THEIR USE IN MOLECULAR IMPRESSION
DK01940836T DK1292828T3 (en) 2000-06-23 2001-06-22 Particles and their use for molecular imprinting
EP01940836A EP1292828B1 (en) 2000-06-23 2001-06-22 Particles and their use in molecular imprinting
AU2001274329A AU2001274329A1 (en) 2000-06-23 2001-06-22 Particles and their use in molecular imprinting

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0015449.2 2000-06-23
GBGB0015449.2A GB0015449D0 (en) 2000-06-23 2000-06-23 Molecular imprinting

Publications (2)

Publication Number Publication Date
WO2001098784A2 WO2001098784A2 (en) 2001-12-27
WO2001098784A3 true WO2001098784A3 (en) 2002-05-30

Family

ID=9894290

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2001/002794 WO2001098784A2 (en) 2000-06-23 2001-06-22 Particles and their use in molecular imprinting

Country Status (11)

Country Link
US (1) US20030186328A1 (en)
EP (1) EP1292828B1 (en)
CN (1) CN1218181C (en)
AT (1) ATE279725T1 (en)
AU (1) AU2001274329A1 (en)
CA (1) CA2412827A1 (en)
DE (1) DE60106442T2 (en)
DK (1) DK1292828T3 (en)
ES (1) ES2228879T3 (en)
GB (1) GB0015449D0 (en)
WO (1) WO2001098784A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1321714C (en) * 2004-05-28 2007-06-20 北京大学 Filling material used for molecule brand solid phase extraction and preparation method thereof
FR2887885B1 (en) * 2005-07-04 2007-09-14 Polyintell Sarl MOLECULAR IMPRESSIONS WITH IMPROVED RECONNAISSANCE CAPACITY, PREPARATION METHOD AND USE THEREOF
KR100861452B1 (en) * 2007-03-05 2008-10-02 성균관대학교산학협력단 Method for preparing surface-imprinted polyacrylate microsphere in the form of core-shell for the selective separation of heavy metal ion
KR101013679B1 (en) * 2007-08-30 2011-02-10 가부시키가이샤 시세이도 Molecular Identification Materials and Manufacturing Methods Thereof
US20100291224A1 (en) * 2008-01-03 2010-11-18 Yen Wah Tong Nanostructures, methods of preparing and uses thereof
US9410949B2 (en) 2010-12-03 2016-08-09 Washington University In St. Louis Label-free detection of renal cancer
US20170172946A1 (en) * 2015-12-21 2017-06-22 Stephan Hau Micro-solid phase extraction
AT519751B1 (en) * 2017-05-04 2018-10-15 Profactor Gmbh Process for the preparation of surfaces with affinity receptors

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001019886A1 (en) * 1999-09-17 2001-03-22 Mip Technologies Ab New molecularly imprinted polymers grafted on solid supports

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458599B1 (en) * 2000-02-18 2002-10-01 Aspira Biosystems, Inc. Compositions and methods for capturing, isolating, detecting, analyzing and quantifying macromolecules

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001019886A1 (en) * 1999-09-17 2001-03-22 Mip Technologies Ab New molecularly imprinted polymers grafted on solid supports

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
GLAD M ET AL: "MOLECULARLY IMPRINTED COMPOSITE POLYMERS BASED ON TRIMETHYLOLPROPANE TRIMETHACRYLATE (TRIM) PARTICLES FOR EFFICIENT ENANTIOMERIC SEPARATIONS", REACTIVE POLYMERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 25, no. 1, 1 May 1995 (1995-05-01), pages 47 - 54, XP000505034, ISSN: 0923-1137 *
GLAD M ET AL: "USE OF SILANE MONOMERS FOR MOLECULAR IMPRINTING AND ENZYME ENTRAPMENT IN POLYSILOXANE-COATED POROUS SILICA", JOURNAL OF CHROMATOGRAPHY, vol. 347, no. 1, 1985, pages 11 - 24, XP002183900, ISSN: 0021-9673 *
VIDYASANKAR SUNDARESAN ET AL: "Selective ligand-exchange adsorbents prepared by template polymerization.", BIOTECHNOLOGY AND BIOENGINEERING, vol. 48, no. 5, 1995, pages 431 - 436, XP002183902, ISSN: 0006-3592 *
VIDYASANKAR, SUNDARESAN ET AL: "Molecularly imprinted ligand-exchange adsorbents for the chiral separation of underivatized amino acids", J. CHROMATOGR., A (1997), 775(1 + 2), 51-63, XP002183901 *

Also Published As

Publication number Publication date
AU2001274329A1 (en) 2002-01-02
WO2001098784A2 (en) 2001-12-27
US20030186328A1 (en) 2003-10-02
CN1440506A (en) 2003-09-03
EP1292828A2 (en) 2003-03-19
DK1292828T3 (en) 2005-01-24
CN1218181C (en) 2005-09-07
CA2412827A1 (en) 2001-12-27
ES2228879T3 (en) 2005-04-16
EP1292828B1 (en) 2004-10-13
DE60106442D1 (en) 2004-11-18
GB0015449D0 (en) 2000-08-16
DE60106442T2 (en) 2005-03-03
ATE279725T1 (en) 2004-10-15

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