WO2001097901A3 - Micro-injection pump - Google Patents

Micro-injection pump Download PDF

Info

Publication number
WO2001097901A3
WO2001097901A3 PCT/US2001/019676 US0119676W WO0197901A3 WO 2001097901 A3 WO2001097901 A3 WO 2001097901A3 US 0119676 W US0119676 W US 0119676W WO 0197901 A3 WO0197901 A3 WO 0197901A3
Authority
WO
WIPO (PCT)
Prior art keywords
micro
syringe
linear
passage
contrast medium
Prior art date
Application number
PCT/US2001/019676
Other languages
French (fr)
Other versions
WO2001097901A2 (en
Inventor
Baruch B Lieber
Ajay K Wakhloo
Stephen Rudin
Joseph A Wodenscheck
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Priority to AU2001271347A priority Critical patent/AU2001271347A1/en
Publication of WO2001097901A2 publication Critical patent/WO2001097901A2/en
Publication of WO2001097901A3 publication Critical patent/WO2001097901A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804Flow controllers
    • A61M5/16827Flow controllers controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/50General characteristics of the apparatus with microprocessors or computers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/007Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media

Abstract

A micro-injection pump (10) for angiography and micro-intervention procedures comprises first and second linear traverses (12, 14) each having a pusher element (12F, 14F) movable by stepper motor drive (12D, 14D) for controlling discharge from a respective micro-syringe (16, 20) engaged by the pusher element (12F, 14F). The first micro-syringe (16) preferably contains a volume of a soluble contrast medium (18), and the second micro-syringe preferably contains a volume of an insoluble contrast medium (22). Fluid discharged by the micro-syringes (16, 20) is directed to a bifurcated micro-droplet generator (28) having a straight primary passage (30D) and an obliquely merging tributary passage (30E). Insoluble contrast medium (22) from the second micro-syringe (20) flows through a micro-sized injection needle (34) extending partially and coaxially within the primary passage (30D) to a termination point just downstream from where the tributary passage (30E) joins the primary passage (30D). Soluble contrast medium (18) from the first micro-syringe (16) passes through the tributary passage (30E) to provide a flow field surrounding the injection needle (34) for shearing off discrete same-sized boluses (22A) from the terminal tip of the injection needle (34) at regular frequency in coordination with a predetermined motion profile of the first and second linear traverses (12, 14). Motion control of the linear traverses is possible using LABVIE® virtual instrumentation software arranged to communicate with a 2-axis indexer control (58) connected to first and second motor indexers (46, 50) for driving the stepper motors (12D, 14D) of the linear traverses (12, 14). Linear potentiometers (84, 86) on the linear traverses (12, 14), rotary encoders (85, 87) connected to the motors (12D, 14D), a flowmeter (92), and pressure transducers (88, 90) indicate motion and flow parameters of the system in real-time to provide a feedback loop in the system so that a desired media delivery waveform is realized.
PCT/US2001/019676 2000-06-22 2001-06-20 Micro-injection pump WO2001097901A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001271347A AU2001271347A1 (en) 2000-06-22 2001-06-20 Micro-injection pump

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21331900P 2000-06-22 2000-06-22
US60/213,319 2000-06-22

Publications (2)

Publication Number Publication Date
WO2001097901A2 WO2001097901A2 (en) 2001-12-27
WO2001097901A3 true WO2001097901A3 (en) 2002-05-30

Family

ID=22794628

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/019676 WO2001097901A2 (en) 2000-06-22 2001-06-20 Micro-injection pump

Country Status (3)

Country Link
US (1) US20020025267A1 (en)
AU (1) AU2001271347A1 (en)
WO (1) WO2001097901A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9211372B2 (en) 2011-08-11 2015-12-15 Osprey Medical, Inc. Systems and methods for limb treatment
US9295816B2 (en) 2009-12-09 2016-03-29 Osprey Medical, Inc. Catheter with distal and proximal ports

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6475188B1 (en) * 1999-05-20 2002-11-05 Anthony David Baxter Bilateral microinjector pump for freely moving animals in an operant chamber
DE10208776A1 (en) * 2002-02-28 2003-09-04 Muefa Ag Infusion unit, useful for the administration of infusion liquids to patients, comprises at least two administration devices, which are mounted on the main body of the unit
US7270648B2 (en) * 2002-12-23 2007-09-18 Farhad Kazemzadeh Drug delivery apparatus
US20050148867A1 (en) * 2003-12-31 2005-07-07 Liebel-Flarsheim Company Injector with changeable syringe constants
ITMO20040028A1 (en) * 2004-02-06 2004-05-06 Sidam Di Azzolini Graziano E C SYRINGE INFUSION PUMP
DE102004031674B3 (en) * 2004-06-30 2005-08-04 Erbe Elektromedizin Gmbh Medical pump for a water jet in liver surgery comprises a drive unit for opening and closing holders and/or coupling units
DE102004031673B4 (en) * 2004-06-30 2009-04-16 Erbe Elektromedizin Gmbh Medical pump
US20060258985A1 (en) * 2005-05-11 2006-11-16 Russell Claudia J Graphical display of medication limits and delivery program
JP5378383B2 (en) * 2007-09-10 2013-12-25 オーソ−クリニカル・ダイアグノスティックス・インコーポレイテッド Aspiration and dispensing of small amounts of liquid
JP5695908B2 (en) 2007-12-10 2015-04-08 バイエル メディカル ケア インコーポレーテッド Continuous fluid transport system and fluid transport method
US9050400B2 (en) * 2008-08-12 2015-06-09 Osprey Medical, Inc. Remote sensing catheter system and methods
US20110087166A1 (en) * 2009-04-06 2011-04-14 Mark Davis Laboratory syringe pumps
DE102011081137B4 (en) * 2011-08-17 2015-03-12 Henkel Ag & Co. Kgaa output system
CN103042386B (en) * 2012-12-31 2015-04-01 安徽工业大学 Rotary bearing mounting system on basis of labview and method for controlling rotary bearing mounting system
US11141123B2 (en) * 2014-12-02 2021-10-12 Koninklijke Philips N.V. Fractional flow reserve determination
CA3207200A1 (en) 2015-01-09 2016-07-14 Bayer Healthcare Llc Multiple fluid delivery system with multi-use disposable set and features thereof
AU2018210313A1 (en) 2017-01-17 2019-06-20 Kaleo, Inc. Medicament delivery devices with wireless connectivity and event detection
US11929160B2 (en) 2018-07-16 2024-03-12 Kaleo, Inc. Medicament delivery devices with wireless connectivity and compliance detection
CN110674564B (en) * 2019-04-09 2024-02-02 哈尔滨理工大学 Main shaft attitude calculation method based on Labview

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256157A (en) * 1991-01-31 1993-10-26 Baxter International Inc. Automated infusion pump with replaceable memory cartridges
US5472403A (en) * 1993-05-11 1995-12-05 The Regents Of The University Of California Device for automatic injection of radionuclide
EP0824022A1 (en) * 1996-08-12 1998-02-18 Microflow Engineering SA Parenteral drug administration system
WO1999021481A2 (en) * 1997-10-24 1999-05-06 Invasatec, Inc. Angiographic injector system with automatic high/low pressure switching
US6063052A (en) * 1993-10-28 2000-05-16 Medrad, Inc. Injection system and pumping system for use therein

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3623474A (en) 1966-07-25 1971-11-30 Medrad Inc Angiographic injection equipment
US3701345A (en) 1970-09-29 1972-10-31 Medrad Inc Angiographic injector equipment
US3812843A (en) 1973-03-12 1974-05-28 Lear Siegler Inc Method and apparatus for injecting contrast media into the vascular system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256157A (en) * 1991-01-31 1993-10-26 Baxter International Inc. Automated infusion pump with replaceable memory cartridges
US5472403A (en) * 1993-05-11 1995-12-05 The Regents Of The University Of California Device for automatic injection of radionuclide
US6063052A (en) * 1993-10-28 2000-05-16 Medrad, Inc. Injection system and pumping system for use therein
EP0824022A1 (en) * 1996-08-12 1998-02-18 Microflow Engineering SA Parenteral drug administration system
WO1999021481A2 (en) * 1997-10-24 1999-05-06 Invasatec, Inc. Angiographic injector system with automatic high/low pressure switching

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9295816B2 (en) 2009-12-09 2016-03-29 Osprey Medical, Inc. Catheter with distal and proximal ports
US9211372B2 (en) 2011-08-11 2015-12-15 Osprey Medical, Inc. Systems and methods for limb treatment
US9555183B2 (en) 2011-08-11 2017-01-31 Osprey Medical, Inc. Systems and methods for limb treatment

Also Published As

Publication number Publication date
US20020025267A1 (en) 2002-02-28
WO2001097901A2 (en) 2001-12-27
AU2001271347A1 (en) 2002-01-02

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