WO2001072838A3 - Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr proteins, and uses thereof - Google Patents

Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr proteins, and uses thereof Download PDF

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Publication number
WO2001072838A3
WO2001072838A3 PCT/US2001/009523 US0109523W WO0172838A3 WO 2001072838 A3 WO2001072838 A3 WO 2001072838A3 US 0109523 W US0109523 W US 0109523W WO 0172838 A3 WO0172838 A3 WO 0172838A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid molecules
molecules encoding
protein coupled
coupled receptors
Prior art date
Application number
PCT/US2001/009523
Other languages
French (fr)
Other versions
WO2001072838A2 (en
Inventor
Ming-Hui Wei
Anibal Cravchik
Francesco Valentina Di
Ellen M Beasley
Original Assignee
Pe Corp Ny
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pe Corp Ny filed Critical Pe Corp Ny
Priority to JP2001571769A priority Critical patent/JP2003528634A/en
Priority to AU2001247766A priority patent/AU2001247766A1/en
Priority to EP01920742A priority patent/EP1278839A2/en
Priority to CA002404533A priority patent/CA2404533A1/en
Publication of WO2001072838A2 publication Critical patent/WO2001072838A2/en
Publication of WO2001072838A3 publication Critical patent/WO2001072838A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides amino acid sequences of peptides that are encoded by genes within the Human genome, the GPCR peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the GPCR peptides and methods of identifying modulators of the GPCR peptides.
PCT/US2001/009523 2000-03-29 2001-03-27 Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr proteins, and uses thereof WO2001072838A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2001571769A JP2003528634A (en) 2000-03-29 2001-03-27 Isolated human G protein-coupled receptors, nucleic acid molecules encoding human GPCR proteins, and uses thereof
AU2001247766A AU2001247766A1 (en) 2000-03-29 2001-03-27 Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr proteins, and uses thereof
EP01920742A EP1278839A2 (en) 2000-03-29 2001-03-27 Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr proteins, and uses thereof
CA002404533A CA2404533A1 (en) 2000-03-29 2001-03-27 Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr proteins, and uses thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US19285300P 2000-03-29 2000-03-29
US60/192,853 2000-03-29
US63559300A 2000-08-09 2000-08-09
US09/635,593 2000-08-09

Publications (2)

Publication Number Publication Date
WO2001072838A2 WO2001072838A2 (en) 2001-10-04
WO2001072838A3 true WO2001072838A3 (en) 2002-02-14

Family

ID=26888432

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/009523 WO2001072838A2 (en) 2000-03-29 2001-03-27 Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr proteins, and uses thereof

Country Status (5)

Country Link
EP (1) EP1278839A2 (en)
JP (1) JP2003528634A (en)
AU (1) AU2001247766A1 (en)
CA (1) CA2404533A1 (en)
WO (1) WO2001072838A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7510845B2 (en) 2000-05-04 2009-03-31 California Institute Of Technology Assay employing G protein-coupled receptor expressed in dorsal root ganglia
US20030092035A1 (en) 2000-05-04 2003-05-15 Anderson David J. Pain signaling molecules
KR100662296B1 (en) * 2002-05-09 2007-01-02 엘지전자 주식회사 Aging Method of Organic Electro Luminescent Module
CN114276460B (en) * 2022-03-04 2022-06-24 水木未来(北京)科技有限公司 Modified GPR75 and use thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999032519A1 (en) * 1997-12-22 1999-07-01 Astrazeneca Canada Inc. Novel g protein-coupled receptor
WO2001016159A1 (en) * 1999-08-27 2001-03-08 Smithkline Beecham Corporation Gpcr, theant
WO2001019983A1 (en) * 1999-09-16 2001-03-22 Solvay Pharmaceuticals B.V. Human g-protein coupled receptor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999032519A1 (en) * 1997-12-22 1999-07-01 Astrazeneca Canada Inc. Novel g protein-coupled receptor
WO2001016159A1 (en) * 1999-08-27 2001-03-08 Smithkline Beecham Corporation Gpcr, theant
WO2001019983A1 (en) * 1999-09-16 2001-03-22 Solvay Pharmaceuticals B.V. Human g-protein coupled receptor

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 13 July 1997 (1997-07-13), TRENKLE T.C.M. ET AL: "Human RAP-PCR products", XP002184794, Database accession no. AF003828 *
DATABASE EMBL [online] 27 March 2000 (2000-03-27), BIRREN B. ET AL: "Homo sapiens chromosome 11, clone RP11-589F4", XP002184795, Database accession no. AC027026 *
See also references of EP1278839A2 *

Also Published As

Publication number Publication date
WO2001072838A2 (en) 2001-10-04
CA2404533A1 (en) 2001-10-04
JP2003528634A (en) 2003-09-30
EP1278839A2 (en) 2003-01-29
AU2001247766A1 (en) 2001-10-08

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