WO2001072833A3 - Human ephrin-like receptor - Google Patents

Human ephrin-like receptor Download PDF

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Publication number
WO2001072833A3
WO2001072833A3 PCT/EP2001/003339 EP0103339W WO0172833A3 WO 2001072833 A3 WO2001072833 A3 WO 2001072833A3 EP 0103339 W EP0103339 W EP 0103339W WO 0172833 A3 WO0172833 A3 WO 0172833A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
receptor
human ephrin
neurons
reagents
disease
Prior art date
Application number
PCT/EP2001/003339
Other languages
French (fr)
Other versions
WO2001072833A2 (en )
Inventor
Shyam Ramakrishnan
Original Assignee
Bayer Ag
Shyam Ramakrishnan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Abstract

Reagents which regulate human ephrin-like receptor and reagents which bind to human ephrin-like receptor gene products can play a role in preventing, ameliorating, or correcting neurodegenerative disorders, including but not limited to, Alzheimer's disease, Parkinson's disease, Huntington's chorea, and amyotrophic lateral sclerosis, and other neuropathies, including regeneration of neurons or in survival of neurons after trauma or stroke. Regulation of human ephrin-like receptor function also can be used to increase or decrease cell proliferation, for example to treat cancer or other hyperproliferative diseases.
PCT/EP2001/003339 2000-03-27 2001-03-23 Human ephrin-like receptor WO2001072833A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US19236900 true 2000-03-27 2000-03-27
US60/192,369 2000-03-27

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AU5621501A AU5621501A (en) 2000-03-27 2001-03-23 Regulation of human ephrin-like receptor

Publications (2)

Publication Number Publication Date
WO2001072833A2 true WO2001072833A2 (en) 2001-10-04
WO2001072833A3 true true WO2001072833A3 (en) 2003-01-16

Family

ID=22709361

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/003339 WO2001072833A3 (en) 2000-03-27 2001-03-23 Human ephrin-like receptor

Country Status (1)

Country Link
WO (1) WO2001072833A3 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0208089D0 (en) * 2002-04-09 2002-05-22 Oxford Glycosciences Uk Ltd Protein

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EM_EST [online] E.B.I. Hinxton U.K.; 14 December 1998 (1998-12-14), XP002211573, Database accession no. AI311841 *
DATABASE EM_EST [online] E.B.I. Hinxton U.K.; 6 January 2000 (2000-01-06), XP002211574, Database accession no. AW274408 *
FOX G M ET AL: "CDNA CLONING AND TISSUE DISTRIBUTION OF FIVE HUMAN EPH-LIKE RECEPTOR PROTEIN-TYROSINE KINASES", ONCOGENE, BASINGSTOKE, HANTS, GB, vol. 10, no. 5, 2 March 1995 (1995-03-02), pages 897 - 905, XP000946743, ISSN: 0950-9232 *
ZHOU RENPING: "The Eph family receptors and ligands.", PHARMACOLOGY & THERAPEUTICS, vol. 77, no. 3, March 1998 (1998-03-01), pages 151 - 181, XP008007426, ISSN: 0163-7258 *

Also Published As

Publication number Publication date Type
WO2001072833A2 (en) 2001-10-04 application

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