WO2001072316A1 - Ayurvedic composition for diabetes - Google Patents

Ayurvedic composition for diabetes Download PDF

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Publication number
WO2001072316A1
WO2001072316A1 PCT/IB2000/000405 IB0000405W WO0172316A1 WO 2001072316 A1 WO2001072316 A1 WO 2001072316A1 IB 0000405 W IB0000405 W IB 0000405W WO 0172316 A1 WO0172316 A1 WO 0172316A1
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WO
WIPO (PCT)
Prior art keywords
composition
mixture
ingredients
blood sugar
herbs
Prior art date
Application number
PCT/IB2000/000405
Other languages
French (fr)
Inventor
Victor Hettigoda
Original Assignee
Victor Hettigoda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Victor Hettigoda filed Critical Victor Hettigoda
Priority to PCT/IB2000/000405 priority Critical patent/WO2001072316A1/en
Publication of WO2001072316A1 publication Critical patent/WO2001072316A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/59Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Abstract

An edible Ayurvedic herbal composition for reducing blood sugar levels in humans, specially suffering from diabetes mellitus comprising a mixture of ingredients selected from the group consisting of Cinnamomum zeylanicum, Artocarpus heterophyllus, Salacia reticulata, Tinospora cordifolia and Pterocarpus marsupium. The mixture of the ingredients of the five selected herbs present in therapeutically effective proportions depending on the required strength of the mixture to treat abnormal levels of blood sugar and diabetes mellitus. This mixture is essentially made using a special grinder called Mortar and Pestle made of timber specially Pestle made of Caryota urens to give additional effects.

Description

AYURVEDIC COMPOSITION FOR DIABETES
INTRODUCTION
The invention ,is for an Ayurvedic composition made by mixing the ingredients of herbal trees to reduce the blood sugar levels and diabetic mellitus of human beings. Ayurvedic preparations are generally made with special procedures and this invention guarantees that there will be no harmful side effects to the human body.
BACKGROUND OF THE INVENTION
Diabetes mellitus is an insidous disease for which there is presently no cure. With humans who are suffering from diabetic mellitus the glucose level in the blood has to be controlled. Unless this is done systematically and regularly it can lead to strokes, untimely heart attacks, loss of eyesight, loss of limbs and ultimately may die as a result of this disease.
Ayurveda treatments in the form of "Charaka Samhita" have been published and known as far back in 8th century B.C. This is still regarded as a comprehensive authoritative treatise in the field of Ayurvedic medicine. There are of course other valuable literature such as Susruta Samhita, Ashtanga Hridya and Madava Nidana describing standards and manufacturing practices of Ayurveda medicines.
According to the Ayurvedic teachings a diabetic condition can occur due to the imbalance of air/vacuum (vata) in a human body. As per the understanding of Ayurvedic system of medicine there are three physical forces (vata, pitta, kapha) that govern the health and determine the physical constitution of living beings.
At present there is no existance of any pure Ayurvedic preparations in the market to combat diabetic mellitus effectively. It is a widely known fact that most of the medicines that are available in the market cause side effects in the human body.
This alleged invention has been formulated improving on ancient formulae from the avilable Ayurvedic literature and by making numerous clinical experiments at the Siddhalepa Ayurveda Hospital which is a well known Ayurvedic hospital in Sri Lanka. These experiments carried out at this well equipped hospital having good laboratory facilities have revealed that these Ayurvedic preparations described hereto are more effective in controlling diabetic mellitus of the human body compared with other medicaments available in the market.
Since there is a long felt need for an Ayurvedic herbal composition in the form of a natural, holistic edible composition, which will serve as a therapeutic agent and maintain the diabetic mellitus at a controlled level experiments were carried out at the Siddhalepa Ayurveda Hospital under the guidance of Ayurvedic Doctors headed by Dr.Victor Hettigoda.
DESCRIPTION
The invention pertains to an Ayurvedic edible composition comprising of ingredients from at least three of the following herbal trees that are abundantly found in Sri Lanka.
l.Cinnamomum zeylanicum 2.Artocarpus heterophyllus 3.Salacia reticulata 4.Tinospora cordifolia 5.Pterocarpus marsupium Preferably the composition comprises of the ingredients of the above trees in the form of bark of Cinnamomum zeylanicum, an infusion of the mature leaves and bark of Artocarpus heterophyllus, roots and stems of Salacia reticulata, infusion of the stem of Tinospora cordifolia and the red Latex tapped from the Pterocarpus marsupium tree.
The ratio of the ingredients used in the said Ayurvedic composition is variable according the requirements of the therapeutic system. Each ingredient from a particular tree may vary as^a percentage (%) based on the weight of the composition of a batch.
The said composition may be made with ingredients from all the five trees or a combination of any three trees and in such a case the proportion of the ingredients used may be increased as per the requirement.
The said composition does not in any way contain any fillers or artificial materials or parts of animals or enhancing agents since such materials are not neccessary and if used, merely will serve to dilute the effecfive concentration of the ingredients of the herbal trees and will also decrease the absorption rate into the blood stream after ingestion. The individual ingredients from the herbs are obtained from reliable sources and milled and mixed as dry powders and this powder is further processed before being compressed into tablets/pills or processed into the form of tea bags. This composition can also be prepared and marketed in the form of an edible herbal tonic.
The methods used in preparing this medicine are ancient and the effectiveness of this medicine has been proved to be better if these proven ancient methods are used.
For instance this method warrants heating in a clay pot using only Cinnamomum tree firewood. The grinding and mixing should be ddhe in a wooden manual grinder where the grinding pole should be made of Kitul tree timber. It is believed and proved beyond doubt that the materials and the methods used in the ancient days produce the best results.
The dosage of the composition of the alleged invention will vary depending on factors such as severity of the disease, age, physical condition, body weight and the diet restrictions of the patient. General guidelines could be incorporated into the packing and different strength compositions could be classified and identified by way of a label or a mark. With these instructions individual patients with a particular body weight and lifestyle and the knowledge of the severity of the disease may readily determine the proper dosage and the recommended composition to control the diabetic mellitus. PREFFERED EMBODIMENT
The following embodiments are presented by way of example only and does not limit the scope of the claims.
1. Cut and prepare bark, leaves, flowers and leaf stalk of Cinnamomum zeylanicum tree to about 1 cm pieces and wash and strain the water and dry in atmospheric air by placing in a clean shady area.
2. Cut and^prepare leaves, roots, flowers, bark and leaf stalk of Artocarpus heterophyllus tree to about 1 cm pieces and wash and strain the water and dry in atmospheric air by placing in a clean shady area.
3. Cut and prepare equal quantities of bark, roots and leaves of Salacia reticulata tree to about, 1 cm pieces and wash and strain the water and dry in atmospheric air by placing in a clean shady area.
4. Cut and prepare stems of Tinospora cordifolia creeper to about 1 cm pieces and wash and strain the water and dry in atmospheric air by placing in a clean shady area. Take the above ingredients in the following proportion:
1,Cinnamomum zeylanicum - 10%
2.Artocarpus heterophyllus - 35%
3.Salacia reticulata - 35%
4.Tinospora cordifolia - 20%
Then introduce the mixture of these ingredients in the proportion of 2:1 with Latex of Pterocarpus marsupium tree in a clay pot which should be gradullay heated with a low flame made out of Cinnamomum firewood until composition is free of moisture. The residue in the clay pot should be ground manually in a wooden manual grinder in the form of Mortar and Pestle having a pestle made out of Caryota Urens timber and the resulting powder should be intensively mixed and dried in a drier to obtain a powder having less than 5% moisture content before packing for use.

Claims

l.An edible Ayurvedic herbal composition for reducing blood sugar levels in humans, especially suffering from diabetes mellitus comprising a mixture of ingredients selected from the group consisting of Cinnamomum zeylanicum, Artocarpus heterophyllus, Salacia reticulata, Tinospora cordifolia and Pterocarpus marsupium.
2.A composition as claimed in claim 1 where the mixture of ingredients of the five selected herbs being present in therapeutically effective propotions depending on the required strength of the mixture to treat the abnormal levels of blood sugar and diabetes mellitus.
3.A composition as claimed in claim 1 where the mixture of ingredients consist of at least three herbs selected from the above said group.
4.A composition as claimed in claim 2 where the mixture of ingredients of the three selected herbs being present in therapeutically effective propotions depending on the required strength of the mixture to treat the abnormal levels of blood sugar and diabeteic mellitus.
5.A composition as claimed in above claims where the composition is presented in the form of a herbal tea bag, herbal pill or a tonic.
6.A method of preparing a composition to reduce the blood sugar level or diabetic mellitus of a human, comprising a mixture of the bark of Cinnamomum zeylanicum tree, an infusion of /the mature leaves and bark of Artocarpus heterophyllus tree, roots and stems of Salacia reticulata tree, infusion of the stem of Tinospora cordifolia tree and the red latex tapped from the Pterocarpus marsupium tree.
7.A method of preparing a composition to reduce the blood sugar level or diabetic mellitus of a human, comprising a mixture of any ingredients from the trees as claimed in claim 6 using a clay pot for heating with Cinnamomum firewood and grinding and mixing with a manual wooden grinder in the form of Mortar and Pestle.
8.A method of preparing a composition to reduce and control the blood sugar level or diabetic mellitus of a human where ingredients from at least three herbs from the group claimed in claim 6 or 7 are present. AMENDED CLAIMS
[received by the International Bureau on 28 February 2001 (28.02.01); original claim 1 replaced by amended claim 1; remaining claims unchanged (1 page)]
1. An edible Ayurvedic herbal composition for reducing blood sugar levels in humans, especially suffering from diabetes mellitus comprising a mixture of ingredients consisting of Cinnamomum zeylanicum, Artocarpus heterophyilus, Salacia reticulate, Tinospora cordifolia and Pterocarpus marsupium.
2. A composition as claimed in claim 1 where the mixture of ingredients of the five selected herbs being present in therapeutically effective proportions depending on the required strength of the mixture to treat the abnormal levels of blood sugar and diabetes mellitus.
3. A composition as claimed in claim 1 where the mixture of ingredients consist of at least three herbs selected from the above said group.
4. A composition as claimed in claim 2 where the mixture of ingredients of the three selected herbs being present in therapeutically effective proportions depending on the required strength of the mixture to treat the abnormal levels of blood sugar and diabetic mellitus. Statement Under Article 19(1) Rule 46.4
The Claim 1 is amended by deleting the words "selected from the group" and leaving all the other words unchanged.
By this amendment to the claim no 1 there is no impact on the description. Deleting of the above words define that the all the five ingredients, viz.: Cinnamomum zeylanicum, Artocarpus heterophyilus, Salacia reticulate, Tinospora cordifolia and Pterocarpus marsupium, have to be used in making the composition claimed for.
The claim 1 as filed define that the composition of the alleged invention may consist any one of the ingredients since the claim defined a mixture of ingredients selected from the group consisting of the said five ingredients. The amended claim 1 defines a composition that consist of all the said five ingredients and therefore the alleged invention of the herbal composition is different from the compositions described and defined in the citations of the ISR.
PCT/IB2000/000405 2000-03-30 2000-03-30 Ayurvedic composition for diabetes WO2001072316A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/IB2000/000405 WO2001072316A1 (en) 2000-03-30 2000-03-30 Ayurvedic composition for diabetes

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU33194/00A AU3319400A (en) 2000-03-30 2000-03-30 Ayurvedic composition for diabetes
DE00911204T DE00911204T1 (en) 2000-03-30 2000-03-30 AYURVEDIC COMPOSITION FOR TREATING DIABETES
EP00911204A EP1425025A1 (en) 2000-03-30 2000-03-30 Ayurvedic composition for diabetes
PCT/IB2000/000405 WO2001072316A1 (en) 2000-03-30 2000-03-30 Ayurvedic composition for diabetes

Publications (1)

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WO2001072316A1 true WO2001072316A1 (en) 2001-10-04

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AU (1) AU3319400A (en)
DE (1) DE00911204T1 (en)
WO (1) WO2001072316A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008041049A1 (en) * 2006-10-02 2008-04-10 Avestha Gengraine Technologies Pvt. Ltd. Cinnamomum zeylanicum plant extracts for the treatment of diabetes and the extraction process thereof
WO2008059310A1 (en) * 2006-11-13 2008-05-22 Avestha Gengraine Technologies Pvt. Ltd Cinnamomum zeylanicum water extracts and their application in diabetes related conditions
WO2008142702A1 (en) * 2007-05-23 2008-11-27 Avesthagen Limited A synergistic ayurvedic / functional food bioactive composition [cincata]
US9849151B2 (en) 2013-11-19 2017-12-26 OmniActive Health Technologies (Canada) Limited Salacia compositions, methods of treatment by their administration, and methods of their preparation
CN108851078A (en) * 2018-06-28 2018-11-23 海南大学 A kind of jackfruit kernel coconut palm ball and preparation method thereof with galgctogogue action

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1149692A (en) * 1997-06-06 1999-02-23 Morishita Jintan Kk Anti-diabetic agent and food product containing the same
US5886029A (en) * 1997-09-05 1999-03-23 Dhaliwal; Kirpal S. Method and composition for treatment of diabetes
EP0956867A1 (en) * 1998-05-12 1999-11-17 Franz-Peter Dr. Liebel Use of flavonoid glycosides, tanning agents and microorganisms for the therapy and prophylaxis of diabetes mellitus

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1149692A (en) * 1997-06-06 1999-02-23 Morishita Jintan Kk Anti-diabetic agent and food product containing the same
US5886029A (en) * 1997-09-05 1999-03-23 Dhaliwal; Kirpal S. Method and composition for treatment of diabetes
EP0956867A1 (en) * 1998-05-12 1999-11-17 Franz-Peter Dr. Liebel Use of flavonoid glycosides, tanning agents and microorganisms for the therapy and prophylaxis of diabetes mellitus

Non-Patent Citations (9)

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Title
ANNALS ACADEMY OF MEDICINE SINGAPORE, vol. 29, no. 1, January 2000 (2000-01-01), pages 37 - 41, ISSN: 0304-4602 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1991, FERNANDO M R ET AL: "EFFECT OF ARTOCARPUS-HETEROPHYLLUS AND ASTERACANTHUS-LONGIFOLIA ON GLUCOSE TOLERANCE IN NORMAL HUMAN SUBJECTS AND IN MATURITY-ONSET DIABETIC PATIENTS", XP002155795, Database accession no. PREV199191133885 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; February 1999 (1999-02-01), KAR AJIT ET AL: "Preliminary studies on the inorganic constituents of some indigenous hypoglycaemic herbs on oral glucose tolerance test.", XP002155796, Database accession no. PREV199900200894 *
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DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; November 1999 (1999-11-01), ONDEROGLU SELDA ET AL: "The evaluation of long-term effects of cinnamon bark and olive leaf on toxicity induced by streptozotocin administration to rats.", XP002155797, Database accession no. PREV200000086419 *
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PATENT ABSTRACTS OF JAPAN vol. 1999, no. 05 31 May 1999 (1999-05-31) *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008041049A1 (en) * 2006-10-02 2008-04-10 Avestha Gengraine Technologies Pvt. Ltd. Cinnamomum zeylanicum plant extracts for the treatment of diabetes and the extraction process thereof
WO2008059310A1 (en) * 2006-11-13 2008-05-22 Avestha Gengraine Technologies Pvt. Ltd Cinnamomum zeylanicum water extracts and their application in diabetes related conditions
WO2008142702A1 (en) * 2007-05-23 2008-11-27 Avesthagen Limited A synergistic ayurvedic / functional food bioactive composition [cincata]
US9849151B2 (en) 2013-11-19 2017-12-26 OmniActive Health Technologies (Canada) Limited Salacia compositions, methods of treatment by their administration, and methods of their preparation
CN108851078A (en) * 2018-06-28 2018-11-23 海南大学 A kind of jackfruit kernel coconut palm ball and preparation method thereof with galgctogogue action

Also Published As

Publication number Publication date
DE00911204T1 (en) 2004-10-21
AU3319400A (en) 2001-10-08
EP1425025A1 (en) 2004-06-09

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