WO2001053474A3 - Flavobacterium heparinum expression system - Google Patents

Flavobacterium heparinum expression system Download PDF

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Publication number
WO2001053474A3
WO2001053474A3 PCT/IB2001/000143 IB0100143W WO0153474A3 WO 2001053474 A3 WO2001053474 A3 WO 2001053474A3 IB 0100143 W IB0100143 W IB 0100143W WO 0153474 A3 WO0153474 A3 WO 0153474A3
Authority
WO
WIPO (PCT)
Prior art keywords
expression system
flavobacterium heparinum
heparinum
flavobacterium
expression
Prior art date
Application number
PCT/IB2001/000143
Other languages
French (fr)
Other versions
WO2001053474A8 (en
WO2001053474A2 (en
Inventor
Hongsheng Su
Shao Zhongqi
Ana Lydia Tkalec
Francoise Blain
Joseph Zimmerman
Original Assignee
Ibex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ibex Pharmaceuticals Inc filed Critical Ibex Pharmaceuticals Inc
Priority to DE60127381T priority Critical patent/DE60127381D1/en
Priority to CA002397562A priority patent/CA2397562A1/en
Priority to EP01942668A priority patent/EP1252291B1/en
Priority to JP2001553935A priority patent/JP2003520598A/en
Priority to AU57908/01A priority patent/AU5790801A/en
Publication of WO2001053474A2 publication Critical patent/WO2001053474A2/en
Publication of WO2001053474A8 publication Critical patent/WO2001053474A8/en
Publication of WO2001053474A3 publication Critical patent/WO2001053474A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Saccharide Compounds (AREA)

Abstract

This invention is directed to Flavobacterium heparinum foruse as a host cell organism for the expression of homologous and heterologous genes.
PCT/IB2001/000143 2000-01-21 2001-01-16 Flavobacterium heparinum expression system WO2001053474A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DE60127381T DE60127381D1 (en) 2000-01-21 2001-01-16 FLAVOBAKTERIUM HEPARINUM EXPRESSION SYSTEM
CA002397562A CA2397562A1 (en) 2000-01-21 2001-01-16 Flavobacterium heparinum expression system
EP01942668A EP1252291B1 (en) 2000-01-21 2001-01-16 Flavobacterium heparinum expression system
JP2001553935A JP2003520598A (en) 2000-01-21 2001-01-16 Flavobacterium heparinum expression system
AU57908/01A AU5790801A (en) 2000-01-21 2001-01-16 Flavobacterium heparinum expression system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17756800P 2000-01-21 2000-01-21
US60/177,568 2000-01-21

Publications (3)

Publication Number Publication Date
WO2001053474A2 WO2001053474A2 (en) 2001-07-26
WO2001053474A8 WO2001053474A8 (en) 2001-08-30
WO2001053474A3 true WO2001053474A3 (en) 2002-01-17

Family

ID=22649110

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2001/000143 WO2001053474A2 (en) 2000-01-21 2001-01-16 Flavobacterium heparinum expression system

Country Status (8)

Country Link
US (2) US6841375B2 (en)
EP (1) EP1252291B1 (en)
JP (1) JP2003520598A (en)
AT (1) ATE357506T1 (en)
AU (1) AU5790801A (en)
CA (1) CA2397562A1 (en)
DE (1) DE60127381D1 (en)
WO (1) WO2001053474A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6131811A (en) 1998-05-29 2000-10-17 E-Micro Corporation Wallet consolidator
WO2001053474A2 (en) * 2000-01-21 2001-07-26 Ibex Pharmaceuticals, Inc. Flavobacterium heparinum expression system
MXPA04001334A (en) * 2001-08-13 2004-05-05 Univ Florida Materials and methods to promote repair of nerve tissue.
DE60334220D1 (en) 2002-06-03 2010-10-28 Massachusetts Inst Technology Rationally Constructed Lyases Derived from Chondroitinase B.
JP2006519977A (en) 2002-11-11 2006-08-31 アフィメトリックス インコーポレイテッド Method for identifying DNA copy number changes
US7767420B2 (en) * 2005-11-03 2010-08-03 Momenta Pharmaceuticals, Inc. Heparan sulfate glycosaminoglycan lyase and uses thereof
US7691613B2 (en) 2006-11-03 2010-04-06 Momenta Pharmaceuticals, Inc. Glycosaminoglycan lyase IV and uses thereof
US7691612B2 (en) 2005-11-03 2010-04-06 Momenta Pharmaceuticals, Inc. Heparan sulfate glycosaminoglycan lyase and uses thereof
US8200440B2 (en) 2007-05-18 2012-06-12 Affymetrix, Inc. System, method, and computer software product for genotype determination using probe array data

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5695968A (en) * 1990-12-07 1997-12-09 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for production of D-α-amino acids

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681733A (en) * 1994-06-10 1997-10-28 Ibex Technologies Nucleic acid sequences and expression systems for heparinase II and heparinase III derived from Flavobacterium heparinum
US6093563A (en) * 1994-07-08 2000-07-25 Ibex Technologies R And D, Inc. Chondroitin lyase enzymes
WO2001053474A2 (en) * 2000-01-21 2001-07-26 Ibex Pharmaceuticals, Inc. Flavobacterium heparinum expression system

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5695968A (en) * 1990-12-07 1997-12-09 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for production of D-α-amino acids

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
RUDY ANTOINE ET AL.: "Isolation and molecular characterization of a novel broad-host-range plasmid from Bordetella bronchiseptica with sequence similarities to plasmids from Gram-positive microorganisms", MOLECULAR MICROBIOLOGY, vol. 6, no. 13, 1992, pages 1785 - 1799, XP001015869 *

Also Published As

Publication number Publication date
AU5790801A (en) 2001-07-31
EP1252291A2 (en) 2002-10-30
JP2003520598A (en) 2003-07-08
WO2001053474A8 (en) 2001-08-30
ATE357506T1 (en) 2007-04-15
EP1252291B1 (en) 2007-03-21
WO2001053474A2 (en) 2001-07-26
US20050153398A1 (en) 2005-07-14
US20010034043A1 (en) 2001-10-25
US6841375B2 (en) 2005-01-11
CA2397562A1 (en) 2001-07-26
DE60127381D1 (en) 2007-05-03

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