WO2001040309A3 - Anti-prostate stem cell antigen (psca) antibody compositions and methods of use - Google Patents
Anti-prostate stem cell antigen (psca) antibody compositions and methods of use Download PDFInfo
- Publication number
- WO2001040309A3 WO2001040309A3 PCT/US2000/029603 US0029603W WO0140309A3 WO 2001040309 A3 WO2001040309 A3 WO 2001040309A3 US 0029603 W US0029603 W US 0029603W WO 0140309 A3 WO0140309 A3 WO 0140309A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- psca
- antibody
- stem cell
- antibodies
- cell antigen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ518477A NZ518477A (en) | 1999-10-29 | 2000-10-27 | Isolated anti-prostate stem cell antigen (PSCA) antibodies that internalise upon binding to PSCA on a mammalian cell, including a PSCA-expressing tumour cell, in vivo |
IL14911600A IL149116A0 (en) | 1999-10-29 | 2000-10-27 | Anti-prostate stem cell antigen (psca) antibody compositions and methods of use |
AU32618/01A AU778199B2 (en) | 1999-10-29 | 2000-10-27 | Anti-prostate stem cell antigen (PSCA) antibody compositions and methods of use |
BR0015224-2A BR0015224A (en) | 1999-10-29 | 2000-10-27 | Isolated prostatic stem cell (psca) anti-antigen, monoclonal anti-psca antibody, isolated nucleic acid, expression vector, cell, host cell, antibody production method, in vitro method composition to kill a cancer cell that expresses psca , use of an anti-psca monoclonal antibody and industrialized article |
EP00991385A EP1226177B1 (en) | 1999-10-29 | 2000-10-27 | Anti-prostate stem cell antigen (psca) antibody compositions and methods of use |
CA002387108A CA2387108A1 (en) | 1999-10-29 | 2000-10-27 | Anti-prostate stem cell antigen (psca) antibody compositions and methods of use |
DE60039448T DE60039448D1 (en) | 1999-10-29 | 2000-10-27 | AGAINST PROSTATE-STATE-TEMPORARY (PSCA) ANTIBODIES AND THEIR USE |
DK00991385T DK1226177T3 (en) | 1999-10-29 | 2000-10-27 | Antibody Compositions for Anti-Prostate Stem Cell Antigen (PSCA) and Applications thereof |
JP2001541063A JP4028237B2 (en) | 1999-10-29 | 2000-10-27 | Anti-prostate stem cell antigen (PSCA) antibody composition and method of use |
NO20021992A NO20021992L (en) | 1999-10-29 | 2002-04-26 | Anti-prostate stem cell antigen (PSCA) antibody preparation and methods of use |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16255899P | 1999-10-29 | 1999-10-29 | |
US60/162,558 | 1999-10-29 | ||
US18287200P | 2000-02-16 | 2000-02-16 | |
US60/182,872 | 2000-02-16 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2001040309A2 WO2001040309A2 (en) | 2001-06-07 |
WO2001040309A3 true WO2001040309A3 (en) | 2001-11-29 |
WO2001040309A9 WO2001040309A9 (en) | 2002-08-15 |
Family
ID=26858866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/029603 WO2001040309A2 (en) | 1999-10-29 | 2000-10-27 | Anti-prostate stem cell antigen (psca) antibody compositions and methods of use |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1226177B1 (en) |
JP (1) | JP4028237B2 (en) |
KR (1) | KR100490077B1 (en) |
CN (1) | CN1413220A (en) |
AT (1) | ATE400587T1 (en) |
AU (1) | AU778199B2 (en) |
BR (1) | BR0015224A (en) |
CA (1) | CA2387108A1 (en) |
DE (1) | DE60039448D1 (en) |
DK (1) | DK1226177T3 (en) |
ES (1) | ES2309012T3 (en) |
IL (1) | IL149116A0 (en) |
NO (1) | NO20021992L (en) |
NZ (1) | NZ518477A (en) |
WO (1) | WO2001040309A2 (en) |
Cited By (2)
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---|---|---|---|---|
US8940871B2 (en) | 2006-03-20 | 2015-01-27 | The Regents Of The University Of California | Engineered anti-prostate stem cell antigen (PSCA) antibodies for cancer targeting |
WO2024138128A2 (en) | 2022-12-23 | 2024-06-27 | Genentech, Inc. | Cereblon degrader conjugates, and uses thereof |
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- 2000-10-27 WO PCT/US2000/029603 patent/WO2001040309A2/en active IP Right Grant
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WO2024138128A2 (en) | 2022-12-23 | 2024-06-27 | Genentech, Inc. | Cereblon degrader conjugates, and uses thereof |
Also Published As
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AU3261801A (en) | 2001-06-12 |
IL149116A0 (en) | 2002-11-10 |
CN1413220A (en) | 2003-04-23 |
DK1226177T3 (en) | 2008-10-06 |
CA2387108A1 (en) | 2001-06-07 |
KR100490077B1 (en) | 2005-05-17 |
NO20021992L (en) | 2002-06-28 |
DE60039448D1 (en) | 2008-08-21 |
BR0015224A (en) | 2002-07-09 |
ATE400587T1 (en) | 2008-07-15 |
JP4028237B2 (en) | 2007-12-26 |
AU778199B2 (en) | 2004-11-25 |
EP1226177A2 (en) | 2002-07-31 |
KR20020047303A (en) | 2002-06-21 |
NO20021992D0 (en) | 2002-04-26 |
NZ518477A (en) | 2004-10-29 |
JP2003515330A (en) | 2003-05-07 |
EP1226177B1 (en) | 2008-07-09 |
WO2001040309A9 (en) | 2002-08-15 |
ES2309012T3 (en) | 2008-12-16 |
WO2001040309A2 (en) | 2001-06-07 |
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