WO2001037914A1 - A method for playing music in real-time synchrony with the heartbeat and a device for the use thereof - Google Patents

A method for playing music in real-time synchrony with the heartbeat and a device for the use thereof Download PDF

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Publication number
WO2001037914A1
WO2001037914A1 PCT/IL2000/000770 IL0000770W WO0137914A1 WO 2001037914 A1 WO2001037914 A1 WO 2001037914A1 IL 0000770 W IL0000770 W IL 0000770W WO 0137914 A1 WO0137914 A1 WO 0137914A1
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WIPO (PCT)
Prior art keywords
pulse
patient
microprocessor
sound
configurations
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PCT/IL2000/000770
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French (fr)
Inventor
Mordechai Lipo
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Mordechai Lipo
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Publication date
Application filed by Mordechai Lipo filed Critical Mordechai Lipo
Priority to AU15464/01A priority Critical patent/AU1546401A/en
Priority to EP00977835A priority patent/EP1409056B1/en
Priority to US10/130,476 priority patent/US7207935B1/en
Publication of WO2001037914A1 publication Critical patent/WO2001037914A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/486—Biofeedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/16—Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/16—Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
    • A61B5/162—Testing reaction times
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0027—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the hearing sense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/04—Heartbeat characteristics, e.g. ECG, blood pressure modulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/04—Heartbeat characteristics, e.g. ECG, blood pressure modulation
    • A61M2230/06—Heartbeat rate only

Definitions

  • the present invention relates to the field of music therapy and provides a method for the improvement of concentration, mood, reinforcement of the immune defense and slowing some of the aging processes in a patient by presentation to the patient of a sequence of musical sound configurations in real time synchrony with the patient's heartbeat with relation to every single pulse.
  • the present invention further relates to a device for use of said method.
  • the rhythm of a healthy individual's heartbeat is not constant. There are certain fluctuations in heartbeat rate from one pulse to another. Dr. Goldberger at Beth Israel Hospital offers a way of creation the music corresponding with heartbeat of a concrete patient.
  • the patient pulse was measured over an entire day by a special monitor with a pocket-size electrocardiogram recorder, the precise intervals between the pulse beats were processed by means of a computer program in accordance with the requirements of statistics to eliminate short-term fluctuations caused by movement or breathing.
  • the daily pulse beat sequence in which the fluctuations had come up was preserved. Thereafter, the time intervals between the heartbeats were converted into integers. Each integer, ranging from 1 to 18, was brought into correspondence with a note of diatonic musical scale.
  • a case in which physical stimuli corresponding with the patient's heartbeat are used is the invention by Pfizer Robert according to the U.S. patent number 4,282,864.
  • the invention relates to a device for inducing a pre-hypnotic state of profound relaxation in an individual, wherein the individual's mind is receptive to suggestion.
  • the device is characterized in that biofeedback signals from the individual are used to produce a plurality of pulsed physical stimuli having a double frequency in relation to the heartbeat rate of the individual.
  • the device includes a heartbeat sensor for producing a first pulse signal, the pulse beats of which are in synchrony with the heartbeat of the individual.
  • An interpolation device is connected with the heartbeat sensor to produce a second pulse signal, the pulses of which occur midway in time between successive pairs of heartbeat pulses, respectively.
  • the interpolation device includes a voltage ramp generator responsive to the first pulse signal to produce a linear voltage ramp output the peaks of which are in synchronization with the pulses of the first signal, respectively, the amplitude of the voltage peaks corresponding with the heartbeat rate of the individual.
  • the interpolation device further includes a peak detector for sensing the peaks of the voltage ramp output and a comparator connected with the peak detector for sensing the midpoint of the voltage ramp output between successive peaks to produce the second pulse signal.
  • a physical stimulus device having a pair of inputs connected with the heartbeat sensor and the interpolation device, respectively, produces a pulsed physical stimulus in response to the first and second signals and having a frequency of twice the heartbeat rate of the individual. Application of such a biofeedback pulsed physical stimulus induces a pre-hypnotic state of profound relaxation in the individual.
  • the technology used in this device allows to present the stimuli to the patient in real time with the patient's heartbeat, the effect of double frequency of the stimuli expresses itself in above-mentioned pre-hypnotic state but not in the improvement of concentration, mood, and feeling of well being that we try to create in the patient with our method.
  • the method of the present invention allows playing music responsive to each pulse beat of the patient in real time.
  • the effect of our invention is due to the simultaneous perception by the patient's brain of both the physiological effects produced by each real heartbeat and the music of the device which is in exact back response to the same heart beat. Summary of the invention
  • the present invention relates to a method for the improvement of concentration, mood, reinforcement of the immune defense and slowing some of the aging processes in a patient by presentation to the patient of a sequence of musical sound configurations in real time synchrony with the patient's heartbeat with relation to every single pulse.
  • the method according to the present invention comprises: a) sensing and transmitting the patient's pulse into analog electric signal; b) digitizing said electric signal; c) using said digitized electric signal as an input signal to a microprocessor; d) bringing said digitized electric signal in correspondence with a sequence of musical sound configurations by means of said microprocessor so as each pulse beat is followed by one of said sound configurations in real time; f) presenting said sequence of musical sound configurations to the patient so as each sound configuration is played in real-time synchrony with respective pulse beat and no longer than until the next pulse beat of the patient.
  • each of said sound configurations can be a member of a plurality of sound configurations responding to the patient's pulse in a pre-determined order.
  • the operator by means of a clock generator, can change the frequency of the sound configurations, i.e., the duration thereof whereas general tempo of the music is defined by the patient's pulse.
  • the aforesaid method does not allow any overlap between the sound configurations.
  • a current sound configuration is stopped before the starting of the next sound configuration if the duration of the first of the two configurations is longer than the time interval between the two respective consecutive pulse beats.
  • Some of aforesaid sound configurations can be played immediately after respective pulse beats, others - with a fixed delay, depending on a program of said microprocessor.
  • the musical sound configurations are at first prepared as wave files in a PC by means of a standard mixer-synthesizer program and downloaded into the memory of said microprocessor from said PC by using a communication card and a special program.
  • the duration of the aforementioned delay, as well as the number and order of said sound configurations can be modified according to individual needs of the patient. This modification is carried out from the PC through the communication interface not in real time.
  • musical arrangement of each of said sound configurations can be altered by means of a performing processor connected to said microprocessor.
  • the alteration is introduced by an operator upon the patient's request and/or according to results of the treatment through a special set-up table.
  • Aforesaid alteration can also be transmitted from said set-up table to the microprocessor through the Internet.
  • said musical sound configurations can be modified not in real time according to a digitized sample of the patient's pulse by a program of said PC. Said sample is taken as aforementioned after a certain time period from the beginning of the treatment, depending on the result thereof.
  • Said digitized sample of the pulse can be transmitted to said PC in real time from the output of the digital level translator through the microprocessor.
  • the method according to the invention also allows the microprocessor to be completely substituted for said PC so as all aforesaid functions of the microprocessor are transferred to the PC.
  • the method provides for a possibility to download said sound configurations from the PC into the memory of the microprocessor through the Internet.
  • the digital sample of the pulse can also be transmitted from the microprocessor to the PC through the Internet.
  • the PC can be connected to the Internet in order to modify and substitute said musical sound configurations. Evaluation of said musical pattern sequence regarding the psychotherapeutic effect thereof is done in advance by an experienced operator guided by their knowledge and intuition on the subject.
  • said sensor can be placed on an artery pulse point or on a fingertip.
  • the patient's pulse picture can be seen on a computer screen or other display.
  • the present invention further relates to a device for the realization of the method.
  • the device allows presentation to the patient of a sequence of musical patterns in real time synchrony with the patient's heartbeat with relation to every single pulse.
  • the device comprises the following units: a) a pulse sensor for picking-up the pulse of the patient and converting said pulse into electrical signal; b) a digital level translator operatively connected to said sensor for digitizing said electric signal; c) a microprocessor operatively connected to said digital level translator for transforming in real time the patient's pulse into a pre-determined sequence of sound configurations, each of said configurations responding to one pulse beat of the patient and lasting no longer than until the next pulse beat.
  • a clock generator for modifying the frequency of said musical sound configurations; e) headphones or loudspeaker operatively connected to said performing processor for presenting the music to the patient.
  • said microprocessor comprises a processing means for stopping said sound configuration before the next sound configuration starts if the duration of the first of the said sound configurations is longer than the time interval between the two respective consecutive pulse beats.
  • Said microprocessor comprises a processing means providing a certain order of responding by said sound configurations to the patient's pulse beats. That makes the music flexible, melodious and more effective.
  • the device according to the invention comprises a communication card through which said sound configurations are registered in the memory of said microprocessor from the PC.
  • the number, order of said sound configurations, as well as the time of delay of a certain sound configuration can be changed from a PC by a special program through another communication card.
  • the microprocessor can be connected with the PC through the Internet.
  • the two communication cards comprise the communication interface of the device according to the invention.
  • said PC can be connected through the Internet with another PC in order to modify the sound sequences and/or substitute them according to results of the treatment.
  • said digital level translator is connected to the PC through the microprocessor for directly transmitting the patient's pulse to said PC. The connection to the PC can be carried out through the Internet as well.
  • the device according to the present invention can also comprise a performing midi-processor and a set-up table, both of which are connected to said microprocessor.
  • Said midi-processor is provided with a processing means for altering musical arrangement of each of said sound configurations. This alteration is introduced by an operator through said set-up table that can also be connected to said microprocessor through the Internet. Similar to the aforementioned, in such an embodiment of the invention, the sound configuration are played in real time synchrony with the patient's pulse, a digital electric signal of which enters the microprocessor.
  • a pressure sensitive or a photoelectric pickup can be used as a pulse sensor.
  • the patient's pulse is picked up by either piezoelectric pressure sensitive or photoelectric sensor 1 and turned into an electric signal.
  • the sensor is fixed in a plastic bucket, which enables to put said sensor on the fingertip.
  • the signal is transmitted to input filter 2, comprising two filters: a low-pass filter against 50/60 Hz noises with peak-to-peak amplitude of up to 10 V and a high-pass filter which cuts noises from 2000 Hz.
  • input filter 2 From input filter 2 the signal is transmitted to input amplifier 3, which is a differential amplifier with a gain range of 50. Therefrom, the signal goes to output high-pass filter 4, which cuts below 100 kHz
  • Translator 5 transforms said AC signal to a digital level between O, 3 V to 3 V by means of an open collector comparator with a threshold of 0,3 V and hysteresis of 50 mV. The comparator output can reach 5 V.
  • microprocessor 6 From converter 5, the signal goes to microprocessor 6, comprising microprocontroller 6, two digital musical processors 6a, clock generator 6b, analog adder 6c and communication interface 6d.
  • microcontroller 6 has three units:
  • 8254 programmable general-purpose timer which consists of 3 16-bit-general-purpose timers.
  • Microcontroller 6 transmits to digital musical processors 6a the sound configurations coming up in real-time synchrony with the patient's pulse beats.
  • Digital musical processor 6a consists of the single musical record/playback chip, in which the musical sound configurations are recorded.
  • the 2 digital musical processor outputs are connected to analog adder 6c to give a 2-sounds' mix.
  • the Programmable Clock Generator output is connected (by a jumper) to an input of microcontroller 6 and to the clock inputs of the two digital musical processors and changes the input clock frequency.
  • This change of the input clock frequency of processor 6a changes the tempo of each of said sound configurations whereas general tempo of the music is defined by the patient's pulse.
  • the musical sound configurations are played according to a special program of microcontroller 6.
  • the Output Audio amplifier interfaces between the digital musical processor and the loudspeaker or the headphones.
  • a potentiometer controls the sound volume.

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Abstract

The invention relates to a method for the improvement of concentration, mood, reinforcement of the immune defense and slowing some of the aging processes in a patient by presentation to the patient of a sequence of musical sound configurations in real time synchrony with the patient's heartbeat with relation to every single pulse, comprising: (a) sensing and transmitting the patient's pulse beating into analog electric signal; (b) digitizing the electric signal; (c) using the digitized electric signal as an input signal to a microprocessor (6); (d) bringing the digitized electric signal in correspondence with a sequence of musical sound configurations by means of the microprocessor (6) so as each pulse beat is followed by one of the sound configurations in real time; (e) presenting the sequence of sound configurations to the patient so as each sound configuration is played in real-time synchrony with respective pulse beat and no longer than until the next pulse beat of the patient.

Description

A METHOD FOR PLAYING MUSIC IN REAL-TIME SYNCHRONY WITH THE HEARTBEAT AND A DEVICE FOR THE USE THEREOF.
Field of the invention
The present invention relates to the field of music therapy and provides a method for the improvement of concentration, mood, reinforcement of the immune defense and slowing some of the aging processes in a patient by presentation to the patient of a sequence of musical sound configurations in real time synchrony with the patient's heartbeat with relation to every single pulse. The present invention further relates to a device for use of said method.
Background of the invention
The positive influence of music corresponding with a patient's heartbeat on the patient's mental and physical health is known in music therapy. The improvement of mood, decrease of depression and level of cortisone in blood after a number of treatment sessions with the use of such music was proved by special research conducted by the Department of Music Education and Music Therapy, the University of Miami, USA. (McKinney CH, Antony MH, Kumar M., Tims FC, McCabe PM, Health Psycho 1997 July; 16(4), P.390-400). According to the method used in said research, the music is played not in a real time synchrony with the patient's heartbeat.
The rhythm of a healthy individual's heartbeat is not constant. There are certain fluctuations in heartbeat rate from one pulse to another. Dr. Goldberger at Beth Israel Hospital offers a way of creation the music corresponding with heartbeat of a concrete patient. In the course of his research, the patient pulse was measured over an entire day by a special monitor with a pocket-size electrocardiogram recorder, the precise intervals between the pulse beats were processed by means of a computer program in accordance with the requirements of statistics to eliminate short-term fluctuations caused by movement or breathing. The daily pulse beat sequence in which the fluctuations had come up was preserved. Thereafter, the time intervals between the heartbeats were converted into integers. Each integer, ranging from 1 to 18, was brought into correspondence with a note of diatonic musical scale. I.e., the changes in heart rate were made proportional to the changes in pitch of the sounds. Thus, a daily heartbeat melody of a patient was generated. Then, Dr. Goldberger chose the rhythm and harmonic accompaniment for each melody. The application of this music produced a positive effect on the state of mind of the patients. Dr. Goldberger explains the medicinal effect of these "heart songs" by the assumption that the variation in pitch of the sounds so produced resonates with the body's own complex variability and scaling. That makes the ground for the conclusion that the positive influence of music on a patient can be reinforced if that music is responsive to each pulse of the patient in real time.
A case in which physical stimuli corresponding with the patient's heartbeat are used is the invention by Pfizer Robert according to the U.S. patent number 4,282,864. The invention relates to a device for inducing a pre-hypnotic state of profound relaxation in an individual, wherein the individual's mind is receptive to suggestion. The device is characterized in that biofeedback signals from the individual are used to produce a plurality of pulsed physical stimuli having a double frequency in relation to the heartbeat rate of the individual.
The device includes a heartbeat sensor for producing a first pulse signal, the pulse beats of which are in synchrony with the heartbeat of the individual. An interpolation device is connected with the heartbeat sensor to produce a second pulse signal, the pulses of which occur midway in time between successive pairs of heartbeat pulses, respectively. The interpolation device includes a voltage ramp generator responsive to the first pulse signal to produce a linear voltage ramp output the peaks of which are in synchronization with the pulses of the first signal, respectively, the amplitude of the voltage peaks corresponding with the heartbeat rate of the individual. The interpolation device further includes a peak detector for sensing the peaks of the voltage ramp output and a comparator connected with the peak detector for sensing the midpoint of the voltage ramp output between successive peaks to produce the second pulse signal. A physical stimulus device having a pair of inputs connected with the heartbeat sensor and the interpolation device, respectively, produces a pulsed physical stimulus in response to the first and second signals and having a frequency of twice the heartbeat rate of the individual. Application of such a biofeedback pulsed physical stimulus induces a pre-hypnotic state of profound relaxation in the individual.
Although the technology used in this device allows to present the stimuli to the patient in real time with the patient's heartbeat, the effect of double frequency of the stimuli expresses itself in above-mentioned pre-hypnotic state but not in the improvement of concentration, mood, and feeling of well being that we try to create in the patient with our method.
The method of the present invention allows playing music responsive to each pulse beat of the patient in real time. We assume that the effect of our invention is due to the simultaneous perception by the patient's brain of both the physiological effects produced by each real heartbeat and the music of the device which is in exact back response to the same heart beat. Summary of the invention
The present invention relates to a method for the improvement of concentration, mood, reinforcement of the immune defense and slowing some of the aging processes in a patient by presentation to the patient of a sequence of musical sound configurations in real time synchrony with the patient's heartbeat with relation to every single pulse. The method according to the present invention comprises: a) sensing and transmitting the patient's pulse into analog electric signal; b) digitizing said electric signal; c) using said digitized electric signal as an input signal to a microprocessor; d) bringing said digitized electric signal in correspondence with a sequence of musical sound configurations by means of said microprocessor so as each pulse beat is followed by one of said sound configurations in real time; f) presenting said sequence of musical sound configurations to the patient so as each sound configuration is played in real-time synchrony with respective pulse beat and no longer than until the next pulse beat of the patient.
In a preferred embodiment of the present invention, each of said sound configurations can be a member of a plurality of sound configurations responding to the patient's pulse in a pre-determined order.
The operator, by means of a clock generator, can change the frequency of the sound configurations, i.e., the duration thereof whereas general tempo of the music is defined by the patient's pulse. The aforesaid method does not allow any overlap between the sound configurations. According to the method, a current sound configuration is stopped before the starting of the next sound configuration if the duration of the first of the two configurations is longer than the time interval between the two respective consecutive pulse beats.
Some of aforesaid sound configurations can be played immediately after respective pulse beats, others - with a fixed delay, depending on a program of said microprocessor.
In a preferred embodiment of the invention the musical sound configurations are at first prepared as wave files in a PC by means of a standard mixer-synthesizer program and downloaded into the memory of said microprocessor from said PC by using a communication card and a special program.
The duration of the aforementioned delay, as well as the number and order of said sound configurations can be modified according to individual needs of the patient. This modification is carried out from the PC through the communication interface not in real time.
In a preferred embodiment of the invention, musical arrangement of each of said sound configurations can be altered by means of a performing processor connected to said microprocessor. The alteration is introduced by an operator upon the patient's request and/or according to results of the treatment through a special set-up table. Aforesaid alteration can also be transmitted from said set-up table to the microprocessor through the Internet.
Furthermore, said musical sound configurations can be modified not in real time according to a digitized sample of the patient's pulse by a program of said PC. Said sample is taken as aforementioned after a certain time period from the beginning of the treatment, depending on the result thereof.
Said digitized sample of the pulse can be transmitted to said PC in real time from the output of the digital level translator through the microprocessor.
The method according to the invention also allows the microprocessor to be completely substituted for said PC so as all aforesaid functions of the microprocessor are transferred to the PC.
If said microprocessor and said PC function alongside each other, the method provides for a possibility to download said sound configurations from the PC into the memory of the microprocessor through the Internet.
The digital sample of the pulse can also be transmitted from the microprocessor to the PC through the Internet.
In a preferred embodiment of the invention, the PC can be connected to the Internet in order to modify and substitute said musical sound configurations. Evaluation of said musical pattern sequence regarding the psychotherapeutic effect thereof is done in advance by an experienced operator guided by their knowledge and intuition on the subject.
According to the method, said sensor can be placed on an artery pulse point or on a fingertip.
The patient's pulse picture can be seen on a computer screen or other display.
The present invention further relates to a device for the realization of the method. According to the method, the device allows presentation to the patient of a sequence of musical patterns in real time synchrony with the patient's heartbeat with relation to every single pulse. The device comprises the following units: a) a pulse sensor for picking-up the pulse of the patient and converting said pulse into electrical signal; b) a digital level translator operatively connected to said sensor for digitizing said electric signal; c) a microprocessor operatively connected to said digital level translator for transforming in real time the patient's pulse into a pre-determined sequence of sound configurations, each of said configurations responding to one pulse beat of the patient and lasting no longer than until the next pulse beat.
d) a clock generator for modifying the frequency of said musical sound configurations; e) headphones or loudspeaker operatively connected to said performing processor for presenting the music to the patient.
To prevent the overlap between the musical patterns, said microprocessor comprises a processing means for stopping said sound configuration before the next sound configuration starts if the duration of the first of the said sound configurations is longer than the time interval between the two respective consecutive pulse beats.
Said microprocessor comprises a processing means providing a certain order of responding by said sound configurations to the patient's pulse beats. That makes the music flexible, melodious and more effective.
The device according to the invention comprises a communication card through which said sound configurations are registered in the memory of said microprocessor from the PC.
The number, order of said sound configurations, as well as the time of delay of a certain sound configuration can be changed from a PC by a special program through another communication card. The microprocessor can be connected with the PC through the Internet.
The two communication cards comprise the communication interface of the device according to the invention.
In a preferred embodiment of the invention, said PC can be connected through the Internet with another PC in order to modify the sound sequences and/or substitute them according to results of the treatment. In a preferred embodiment of the invention, said digital level translator is connected to the PC through the microprocessor for directly transmitting the patient's pulse to said PC. The connection to the PC can be carried out through the Internet as well.
The device according to the present invention can also comprise a performing midi-processor and a set-up table, both of which are connected to said microprocessor. Said midi-processor is provided with a processing means for altering musical arrangement of each of said sound configurations. This alteration is introduced by an operator through said set-up table that can also be connected to said microprocessor through the Internet. Similar to the aforementioned, in such an embodiment of the invention, the sound configuration are played in real time synchrony with the patient's pulse, a digital electric signal of which enters the microprocessor.
According to the method of the invention, a pressure sensitive or a photoelectric pickup can be used as a pulse sensor.
Detailed description of a preferred embodiment
The present invention will be described in detail by figure 1. This description is not intended to limit the scope of the present invention, but only to illustrate the preferred embodiment.
According to the embodiment, the patient's pulse is picked up by either piezoelectric pressure sensitive or photoelectric sensor 1 and turned into an electric signal. The sensor is fixed in a plastic bucket, which enables to put said sensor on the fingertip. The signal is transmitted to input filter 2, comprising two filters: a low-pass filter against 50/60 Hz noises with peak-to-peak amplitude of up to 10 V and a high-pass filter which cuts noises from 2000 Hz. From input filter 2 the signal is transmitted to input amplifier 3, which is a differential amplifier with a gain range of 50. Therefrom, the signal goes to output high-pass filter 4, which cuts below 100 kHz
After filter 4, the signal is digitized by digital level translator 5. Translator 5 transforms said AC signal to a digital level between O, 3 V to 3 V by means of an open collector comparator with a threshold of 0,3 V and hysteresis of 50 mV. The comparator output can reach 5 V.
From converter 5, the signal goes to microprocessor 6, comprising microprocontroller 6, two digital musical processors 6a, clock generator 6b, analog adder 6c and communication interface 6d. Microcontroller 6 has three units:
1) 8032 microcontroller for general control of sound and communication;
2) The memory:
16 KBYTES of RAM; 32 KBYTES of EPROM; 32 Kbytes of EEPROM;
3) 8254 programmable general-purpose timer, which consists of 3 16-bit-general-purpose timers.
Microcontroller 6 transmits to digital musical processors 6a the sound configurations coming up in real-time synchrony with the patient's pulse beats.
Digital musical processor 6a consists of the single musical record/playback chip, in which the musical sound configurations are recorded.
The 2 digital musical processor outputs are connected to analog adder 6c to give a 2-sounds' mix.
Programmable Clock Generator 6c
The Programmable Clock Generator output is connected (by a jumper) to an input of microcontroller 6 and to the clock inputs of the two digital musical processors and changes the input clock frequency. This change of the input clock frequency of processor 6a changes the tempo of each of said sound configurations whereas general tempo of the music is defined by the patient's pulse. The musical sound configurations are played according to a special program of microcontroller 6.
Output Audio Amplifier 6e
The Output Audio amplifier interfaces between the digital musical processor and the loudspeaker or the headphones. A potentiometer controls the sound volume.
RS232 communication interface 6d
The RS232 communication interfaces between an IBM PC and microprocessor 6 for software downloading and debugging.

Claims

Claims
1. A method for the improvement of concentration, mood, reinforcement of the immune defense and slowing some of the aging processes in a patient by presentation to the patient of a sequence of musical sound configurations in real time synchrony with the patient's heartbeat with relation to every single pulse, comprising;
(a) sensing and transmitting the patient's pulse beating into analog electric signal;
(b) digitizing said electric signal;
(c) using said digitized electric signal as an input signal to a microprocessor;
(d) bringing said digitized electric signal in correspondence with a sequence of musical sound configurations by means of said microprocessor so as each pulse beat is followed by one of said sound configurations in real time;
e) presenting said sequence of sound configurations to the patient so as each sound configuration is played in real-time synchrony with respective pulse beat and no longer than until the next pulse beat of the patient.
2. A method according to claim 1 wherein each of said sound configurations is a member of a plurality of sound configurations responding to the patient's pulse beats in a pre-determined order.
3. A method according to claims 1 , 2 wherein said sound configuration is stopped before the next sound configuration starts if the duration of the first of said two configurations is longer than the time interval between the two respective consecutive pulse beats.
4. A method according to any of the preceding claims wherein said sound configuration is played in response to a pulse beat immediately after said pulse beat.
5. A method according to claims 1 - 3 wherein said sound configuration is played in response to a pulse beat with a fixed delay.
6. A method according to any of the preceding claims wherein the sound configurations are at first prepared as wave files in the PC and downloaded into the memory of said microprocessor through a communication interface.
7. A method according to any of the preceding claims wherein the length of said delay, the number and the order of the sound configurations can be changed not in real time from said PC through said communication interface.
8. A method according to claims 1 - 5 and 7 wherein musical arrangement of each of said sound configurations is altered by means of a performing processor connected to said microprocessor, said alteration being introduced by an operator through a set-up table also connected to said microprocessor.
9. A method according to any of the preceding claims wherein said sound configurations are modified not in real time according to a digitized sample of the patient's pulse by a program of said PC, said sample being taken according to the method of claim 1 after a certain time period from the beginning of the treatment, depending on the result thereof.
10. A method according to claim 9 wherein said digitized sample of the patient's pulse signal is transmitted from the microprocessor to said PC in real time.
11. A method according to claim 8 wherein said set-up is transmitted from said set-up table to said microprocessor through the Internet.
12. A method according to the preceding claims wherein all functions of said microprocessor are performed by said PC so that said microprocessor is completely substituted for said PC.
13. A method according to any of preceding claims except for claim 12 wherein said sound configurations are transmitted from said PC to the memory of said microprocessor through the Internet.
14. A method according to claim 10 wherein said digital sample of the patient's pulse signal is transmitted from said microprocessor to said PC through the Internet.
15. A method according to any of the preceding claims wherein evaluation of said music regarding the psychotherapeutic effect thereof according to claim 1 is done in advance by an experienced operator guided by their knowledge and intuition on the subject.
16. A method according to any of the preceding claims wherein the pulse sensor is placed on an artery pulse point.
17. A method according to claims 1 - 15 wherein the pulse sensor is placed on a fingertip.
18. A method according to any of the preceding claims wherein the pulse picture of the patient is presented on a display.
19. A method according to claims 1 - 19 wherein said display is a computer screen.
20. A device for presentation of music to the patient in real-time synchrony with the patient's heartbeat with relation to every single pulse according to the method as defined in claim 1 , comprising; a) a pulse sensor for picking-up the pulse of the patient and converting said pulse into electrical signal; b) a digital level translator operatively connected to said sensor for digitizing said electric signal; c) a microprocessor operatively connected to said level translator for translating in real time the patient's pulse into a pre-determined sequence of musical sound configurations, each of said configurations responding one pulse beat of the patient and lasting no longer than until the next pulse beat. d) a clock generator for giving said musical sound configurations a desirable frequency; e) headphones or loudspeaker operatively connected to said performing processor for presenting the music to the patient.
21. A device according to claim 20 wherein said microprocessor comprises a processing means for stopping said sound configuration before the starting of the next sound configuration if the duration of the first of said sound configurations is longer than the time interval between the two respective consecutive pulse beats.
22. A device according to claims 20, 21 wherein said microprocessor comprises a processing means for providing a predetermined order of responding the patient's pulse beats by said sound configurations.
23. A device according to claims 20 - 22, having a communication card through which said sound configurations are downloaded into the memory of said microprocessor from a PC.
24. A device according to claims 20 - 23, having the second communication card through which the number, order and temporal arrangement of said sound configurations can be changed from said PC.
25. A device according to claims 20 - 24 wherein said microprocessor comprises a communication interface to said PC for recording said sound configurations in the memory chip of said microprocessor and for changing the number, order and temporal arrangement of said sound configurations.
26. A device according to claims 20 - 25, further comprising a performing midi-processor and a set-up table both of which are connected to said microprocessor, said midi-processor comprising a processing means for carrying out a desirable change to musical arrangement of each of said sound configurations, said change being introduced through said set-up table.
27. A device according to claims 20 - 26 wherein said PC comprises each of said processing means so that said microprocessor is completely substituted by said PC.
28. A device according to claims 20 - 27 wherein said microprocessor or said PC is connected with the Internet for modifying said sound configurations and changing musical arrangement thereof.
29. A device according to claims 20 - 28 wherein said digital level translator is directly connected to said PC through a button on the portable case of the device for sending to the PC a digitized sample of the patient's pulse.
30. A device according to claim 29 wherein said digital level translator is connected to the Internet for sending said digitized sample of the patient pulse to a PC for analysis and appropriate modifying of said sound configurations.
31. A device according to claims 20 - 30 wherein said pulse sensor is a pressure sensitive sensor.
32. A device according to claims 20 - 31 wherein said pulse sensor is a photoelectric sensor.
PCT/IL2000/000770 1999-11-21 2000-11-19 A method for playing music in real-time synchrony with the heartbeat and a device for the use thereof WO2001037914A1 (en)

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EP00977835A EP1409056B1 (en) 1999-11-21 2000-11-19 A method for playing music in real-time synchrony with the heartbeat and a device for the use thereof
US10/130,476 US7207935B1 (en) 1999-11-21 2000-11-19 Method for playing music in real-time synchrony with the heartbeat and a device for the use thereof

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10100663A1 (en) * 2001-01-02 2002-07-04 Stielau Guenter EEG stimulation method and appliance include sensors, biofeedback input, evaluation system, modulation signal, stimulation system and signal
WO2003018097A1 (en) * 2001-08-30 2003-03-06 Thomas Fiebelkorn Device for the treatment of persons by music therapy
US7177672B2 (en) 2002-12-16 2007-02-13 Polar Electro Oy Coding heart rate information
EP1768449A1 (en) * 2005-09-27 2007-03-28 Siemens Audiologische Technik GmbH Device and method of adjusting a hearing apparatus based on biometric data
WO2008148433A1 (en) * 2007-06-08 2008-12-11 Sony Ericsson Mobile Communications Ab Sleeping mode accessory

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL130818A (en) 1999-07-06 2005-07-25 Intercure Ltd Interventive-diagnostic device
US8672852B2 (en) * 2002-12-13 2014-03-18 Intercure Ltd. Apparatus and method for beneficial modification of biorhythmic activity
US7236154B1 (en) 2002-12-24 2007-06-26 Apple Inc. Computer light adjustment
JP4739762B2 (en) * 2002-12-30 2011-08-03 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Audio playback apparatus, audio feedback system and method
US7616097B1 (en) 2004-07-12 2009-11-10 Apple Inc. Handheld devices as visual indicators
US7521623B2 (en) * 2004-11-24 2009-04-21 Apple Inc. Music synchronization arrangement
US7894177B2 (en) * 2005-12-29 2011-02-22 Apple Inc. Light activated hold switch
US7745716B1 (en) * 2003-12-15 2010-06-29 Michael Shawn Murphy Musical fitness computer
KR101203492B1 (en) 2004-02-19 2012-11-21 코닌클리케 필립스 일렉트로닉스 엔.브이. Audio pacing device
KR101194165B1 (en) * 2004-02-19 2012-10-24 코닌클리케 필립스 일렉트로닉스 엔.브이. Audio interval training device
US20070189544A1 (en) 2005-01-15 2007-08-16 Outland Research, Llc Ambient sound responsive media player
US7562117B2 (en) * 2005-09-09 2009-07-14 Outland Research, Llc System, method and computer program product for collaborative broadcast media
US7603414B2 (en) * 2005-09-09 2009-10-13 Outland Research, Llc System, method and computer program product for collaborative background music among portable communication devices
US20070213110A1 (en) * 2005-01-28 2007-09-13 Outland Research, Llc Jump and bob interface for handheld media player devices
US20070106663A1 (en) * 2005-02-01 2007-05-10 Outland Research, Llc Methods and apparatus for using user personality type to improve the organization of documents retrieved in response to a search query
US7519537B2 (en) * 2005-07-19 2009-04-14 Outland Research, Llc Method and apparatus for a verbo-manual gesture interface
US8176101B2 (en) 2006-02-07 2012-05-08 Google Inc. Collaborative rejection of media for physical establishments
US20110072955A1 (en) 2005-10-06 2011-03-31 Turner William D System and method for pacing repetitive motion activities
US20130228063A1 (en) * 2005-10-06 2013-09-05 William D. Turner System and method for pacing repetitive motion activities
US7825319B2 (en) * 2005-10-06 2010-11-02 Pacing Technologies Llc System and method for pacing repetitive motion activities
US7586032B2 (en) * 2005-10-07 2009-09-08 Outland Research, Llc Shake responsive portable media player
US20070075127A1 (en) * 2005-12-21 2007-04-05 Outland Research, Llc Orientation-based power conservation for portable media devices
EP1811496B1 (en) * 2006-01-20 2009-06-17 Yamaha Corporation Apparatus for controlling music reproduction and apparatus for reproducing music
TW200820225A (en) * 2006-10-25 2008-05-01 Taiwan Chest Disease Ass Home-based exercise tranining method and system guided by automatically assessment and selecting music
JP4311466B2 (en) * 2007-03-28 2009-08-12 ヤマハ株式会社 Performance apparatus and program for realizing the control method
US7956274B2 (en) * 2007-03-28 2011-06-07 Yamaha Corporation Performance apparatus and storage medium therefor
US8269093B2 (en) 2007-08-21 2012-09-18 Apple Inc. Method for creating a beat-synchronized media mix
US10713341B2 (en) * 2011-07-13 2020-07-14 Scott F. McNulty System, method and apparatus for generating acoustic signals based on biometric information
US9183822B2 (en) * 2012-05-23 2015-11-10 Google Inc. Music selection and adaptation for exercising
US10459972B2 (en) 2012-09-07 2019-10-29 Biobeats Group Ltd Biometric-music interaction methods and systems
US9330680B2 (en) 2012-09-07 2016-05-03 BioBeats, Inc. Biometric-music interaction methods and systems
US20140338516A1 (en) * 2013-05-19 2014-11-20 Michael J. Andri State driven media playback rate augmentation and pitch maintenance
US9269341B1 (en) * 2013-06-30 2016-02-23 Second Wind Technologies, Inc. Method for processing music to match runners tempo
CN106067308A (en) * 2016-06-07 2016-11-02 四川长虹网络科技有限责任公司 The regulation equipment of music speed, system and method is changed by human heart rate
JP2018191159A (en) * 2017-05-08 2018-11-29 山▲崎▼ 薫 Moving image distribution method
US10636400B2 (en) * 2018-04-25 2020-04-28 Joseph William Patitucci Method for producing and streaming music generated from biofeedback
US10909956B2 (en) * 2019-05-28 2021-02-02 Joseph William Patitucci Apparatus and method for producing and streaming music generated from plants
CN111939423B (en) * 2020-06-29 2022-07-12 杨铭轲 Sleep-in guiding method and device based on self-heartbeat rhythm and computer equipment

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4282864A (en) 1980-05-12 1981-08-11 Pizer Robert S Method and apparatus for inducing a pre-hypnotic state
DE3546052A1 (en) * 1985-12-24 1987-06-25 Helge Berz Method and device for enhancing the human performance
US4896675A (en) * 1988-06-10 1990-01-30 Mitsubishi Denki Kabushiki Kaisha Apparatus for monitoring degree of mental tension
WO1995017854A1 (en) * 1993-12-28 1995-07-06 Cognitech Corporation Trophotropic response system
DE9418874U1 (en) * 1994-11-24 1995-10-19 Hennl, Wilhelm, Dipl.-Ing., 86609 Donauwörth Device for acoustically influencing physical and psychological functions

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE354052C (en) 1919-12-21 1922-05-29 Max Helf Device for coupling the towing vehicle and trailer with a coupling piece that can be moved in its longitudinal direction and pivoted to the side
US4181134A (en) * 1977-09-21 1980-01-01 Mason Richard C Cardiotachometer
CA1143014A (en) * 1980-04-24 1983-03-15 Her Majesty The Queen, In Right Of Canada, As Represented By The Minister Of National Defence Portable digital heart rate meter/ stethoscope
JP4096376B2 (en) * 1996-07-09 2008-06-04 セイコーエプソン株式会社 Relaxation instruction equipment
JPH11253572A (en) * 1998-03-09 1999-09-21 Csk Corp Practicing device for health improvement
US6370433B1 (en) * 1998-04-29 2002-04-09 Medtronic, Inc. Interrogation of an implantable medical device using broadcast audible sound communication
US6230047B1 (en) * 1998-10-15 2001-05-08 Mchugh David Musical listening apparatus with pulse-triggered rhythm

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4282864A (en) 1980-05-12 1981-08-11 Pizer Robert S Method and apparatus for inducing a pre-hypnotic state
DE3546052A1 (en) * 1985-12-24 1987-06-25 Helge Berz Method and device for enhancing the human performance
US4896675A (en) * 1988-06-10 1990-01-30 Mitsubishi Denki Kabushiki Kaisha Apparatus for monitoring degree of mental tension
WO1995017854A1 (en) * 1993-12-28 1995-07-06 Cognitech Corporation Trophotropic response system
DE9418874U1 (en) * 1994-11-24 1995-10-19 Hennl, Wilhelm, Dipl.-Ing., 86609 Donauwörth Device for acoustically influencing physical and psychological functions

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10100663A1 (en) * 2001-01-02 2002-07-04 Stielau Guenter EEG stimulation method and appliance include sensors, biofeedback input, evaluation system, modulation signal, stimulation system and signal
WO2003018097A1 (en) * 2001-08-30 2003-03-06 Thomas Fiebelkorn Device for the treatment of persons by music therapy
US7177672B2 (en) 2002-12-16 2007-02-13 Polar Electro Oy Coding heart rate information
EP1768449A1 (en) * 2005-09-27 2007-03-28 Siemens Audiologische Technik GmbH Device and method of adjusting a hearing apparatus based on biometric data
WO2008148433A1 (en) * 2007-06-08 2008-12-11 Sony Ericsson Mobile Communications Ab Sleeping mode accessory
US7637859B2 (en) 2007-06-08 2009-12-29 Sony Ericsson Mobile Communications Ab Sleeping mode accessory

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AU1546401A (en) 2001-06-04
IL133061A (en) 2010-06-30

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