WO2001029072A3 - P15paf cell cycle proteins associated with pcna, compositions and methods of use - Google Patents

P15paf cell cycle proteins associated with pcna, compositions and methods of use Download PDF

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Publication number
WO2001029072A3
WO2001029072A3 PCT/US2000/041296 US0041296W WO0129072A3 WO 2001029072 A3 WO2001029072 A3 WO 2001029072A3 US 0041296 W US0041296 W US 0041296W WO 0129072 A3 WO0129072 A3 WO 0129072A3
Authority
WO
WIPO (PCT)
Prior art keywords
present
methods
cell cycle
compositions
polypeptides
Prior art date
Application number
PCT/US2000/041296
Other languages
French (fr)
Other versions
WO2001029072A2 (en
WO2001029072A9 (en
Inventor
Ying Luo
Peiwen Yu
Betty Huang
Original Assignee
Rigel Pharmaceuticals Inc
Ying Luo
Peiwen Yu
Betty Huang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rigel Pharmaceuticals Inc, Ying Luo, Peiwen Yu, Betty Huang filed Critical Rigel Pharmaceuticals Inc
Priority to JP2001531870A priority Critical patent/JP2003513231A/en
Priority to EP00984557A priority patent/EP1224470A2/en
Priority to AU21158/01A priority patent/AU2115801A/en
Priority to CA002387731A priority patent/CA2387731A1/en
Publication of WO2001029072A2 publication Critical patent/WO2001029072A2/en
Publication of WO2001029072A3 publication Critical patent/WO2001029072A3/en
Publication of WO2001029072A9 publication Critical patent/WO2001029072A9/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
PCT/US2000/041296 1999-10-18 2000-10-18 P15paf cell cycle proteins associated with pcna, compositions and methods of use WO2001029072A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2001531870A JP2003513231A (en) 1999-10-18 2000-10-18 PCNA-related P15PAF cell cycle proteins, compositions and uses
EP00984557A EP1224470A2 (en) 1999-10-18 2000-10-18 P15paf cell cycle proteins associated with pcna, compositions and methods of use
AU21158/01A AU2115801A (en) 1999-10-18 2000-10-18 P15paf cell cycle proteins associated with pcna, compositions and methods of use
CA002387731A CA2387731A1 (en) 1999-10-18 2000-10-18 P15paf cell cycle proteins associated with pcna, compositions and methods of use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42009299A 1999-10-18 1999-10-18
US09/420,092 1999-10-18

Publications (3)

Publication Number Publication Date
WO2001029072A2 WO2001029072A2 (en) 2001-04-26
WO2001029072A3 true WO2001029072A3 (en) 2002-01-17
WO2001029072A9 WO2001029072A9 (en) 2002-08-01

Family

ID=23665049

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/041296 WO2001029072A2 (en) 1999-10-18 2000-10-18 P15paf cell cycle proteins associated with pcna, compositions and methods of use

Country Status (5)

Country Link
EP (1) EP1224470A2 (en)
JP (1) JP2003513231A (en)
AU (1) AU2115801A (en)
CA (1) CA2387731A1 (en)
WO (1) WO2001029072A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0410498D0 (en) * 2004-05-11 2004-06-16 Cyclacel Ltd Crystal

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000055350A1 (en) * 1999-03-12 2000-09-21 Human Genome Sciences, Inc. Human cancer associated gene sequences and polypeptides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000055350A1 (en) * 1999-03-12 2000-09-21 Human Genome Sciences, Inc. Human cancer associated gene sequences and polypeptides

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 8 February 2001 (2001-02-08), XP002171327 *
DATABASE SWISS-PROT 15 July 1998 (1998-07-15), "Hypothetical protein KIAA0101", XP002171326 *
NAGASE, T. ET AL.: "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1", DNA RESEARCH, vol. 2, no. 1, 28 February 1995 (1995-02-28), pages 37 - 43, XP001011422 *
YU, PEIWEN ET AL: "p15PAF, a novel PCNA associated factor with increased expression in tumor tissues", ONCOGENE, 20(4), 484-489, 25 January 2001 (2001-01-25), XP001011484 *

Also Published As

Publication number Publication date
EP1224470A2 (en) 2002-07-24
JP2003513231A (en) 2003-04-08
WO2001029072A2 (en) 2001-04-26
WO2001029072A9 (en) 2002-08-01
CA2387731A1 (en) 2001-04-26
AU2115801A (en) 2001-04-30

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