New! Search for patents from more than 100 countries including Australia, Brazil, Sweden and more

WO2001024837A8 - Preservative system for ophthalmic solutions - Google Patents

Preservative system for ophthalmic solutions

Info

Publication number
WO2001024837A8
WO2001024837A8 PCT/US2000/027524 US0027524W WO0124837A8 WO 2001024837 A8 WO2001024837 A8 WO 2001024837A8 US 0027524 W US0027524 W US 0027524W WO 0124837 A8 WO0124837 A8 WO 0124837A8
Authority
WO
WIPO (PCT)
Prior art keywords
preservative system
ophthalmic solutions
preservative
solution
irritating
Prior art date
Application number
PCT/US2000/027524
Other languages
French (fr)
Other versions
WO2001024837A1 (en
Inventor
Jeanne Y Ellis
Original Assignee
Vista Scient Llc
Jeanne Y Ellis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US15795699P priority Critical
Priority to US60/157,956 priority
Application filed by Vista Scient Llc, Jeanne Y Ellis filed Critical Vista Scient Llc
Publication of WO2001024837A1 publication Critical patent/WO2001024837A1/en
Publication of WO2001024837A8 publication Critical patent/WO2001024837A8/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L12/00Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/141Biguanides, e.g. chlorhexidine

Abstract

Multi-use ophthalmic solutions require a preservative system designed to kill microbes that come in contact with the solution. Failure of the preservative system can pose potential ocular infection hazard to the solution user. Preservative systems must be both efficacious and non-irritating, a balance which is often difficult to achieve. The present invention describes a three-component preservative system for ophthalmic solutions which is both effective in preventing microbial growth and is compatible with the ocular environment.
PCT/US2000/027524 1999-10-06 2000-10-06 Preservative system for ophthalmic solutions WO2001024837A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US15795699P true 1999-10-06 1999-10-06
US60/157,956 1999-10-06

Publications (2)

Publication Number Publication Date
WO2001024837A1 WO2001024837A1 (en) 2001-04-12
WO2001024837A8 true WO2001024837A8 (en) 2001-07-19

Family

ID=22566065

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/027524 WO2001024837A1 (en) 1999-10-06 2000-10-06 Preservative system for ophthalmic solutions

Country Status (1)

Country Link
WO (1) WO2001024837A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6528464B1 (en) * 2001-08-17 2003-03-04 Bausch & Lomb Incorporated Composition and method for inhibiting uptake of biguanide antimicrobials by hydrogels
US20050214382A1 (en) 2004-03-29 2005-09-29 Erning Xia Zinc preservative composition and method of use
WO2008121644A2 (en) 2007-03-30 2008-10-09 Johnson & Johnson Vision Care, Inc. Preparation of antimicrobial contact lenses with reduced haze using swelling agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046706A (en) * 1976-04-06 1977-09-06 Flow Pharmaceuticals, Inc. Contact lens cleaning composition
US4354952A (en) * 1981-03-12 1982-10-19 Bausch & Lomb Incorporated Contact lens disinfecting and preserving solution comprising chlorhexidine and salts thereof
US4537746A (en) * 1983-12-29 1985-08-27 Bausch & Lomb Incorporated Methods for disinfecting and preserving contact lenses

Also Published As

Publication number Publication date
WO2001024837A1 (en) 2001-04-12

Similar Documents

Publication Publication Date Title
Siqueira Jr et al. Mechanisms of antimicrobial activity of calcium hydroxide: a critical review
US4560491A (en) Soft contact lens wetting solution and in-eye comfort solution containing preservative and method
US20110052664A1 (en) Antimicrobial Medical Dressings and Protecting Wounds and Catheter Sites
USRE32672E (en) Method for simultaneously cleaning and disinfecting contact lenses using a mixture of peroxide and proteolytic enzyme
US5523012A (en) Hydrogen peroxide disinfection solutions
US6022732A (en) Hydrogen peroxide destroying compositions and methods of using same
WO2002062775A1 (en) 2-acylaminothiazole derivative or its salt
US5746972A (en) Compositions and methods for disinfecting and cleaning contact lenses
WO1994027436A1 (en) Preservative systems with enhanced antimicrobial activity
Ayres et al. Effect of permeabilizers on antibiotic sensitivity of Pseudomonas aeruginosa
US6020375A (en) Bactericidal composition
US5565197A (en) Method which utilizes a haloperoxidase composition to inhibit the growth of microorganisms which cause sexually transmitted diseases
US5165918A (en) Antimicrobial ophthalmic solutions containing dodecyl-dimethyl-(2 phenoxyethyl)-ammonium bromide and methods of using the same
WO1992004921A1 (en) Apparatus and method for disinfecting a contact lens and detecting the presence of an oxidative disinfectant
JPH10236961A (en) Ophthalmic agent using electrolytic acid water
JPH11249087A (en) Light agent for contact lens
JPH08133911A (en) Antimicrobial composition
WO1990013542A1 (en) Anti-hiv drug
EP0884058A1 (en) Solution for preserving and sterilizing contact lenses
JP2001264707A (en) Disinfecting and preserving solution for contact lens
US5840250A (en) Compositions and methods for disinfecting a contact lens and detecting the presence of an oxidative disinfectant
US6793941B1 (en) Contact lens and opthalmic solutions
Diaz-Buxo Comparison of peritonitis rates with CCPD, manual CAPD, Y-sets, O-sets, UV devices and sterile weld
WO2003009859A1 (en) Immunotherapy for humans
CA2302720A1 (en) Anticoagulant/sterilizing compositions and methods

Legal Events

Date Code Title Description
AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

AK Designated states

Kind code of ref document: A1

Designated state(s): CA JP US

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: C1

Designated state(s): CA JP US

WR Later publication of a revised version of an international search report
AL Designated countries for regional patents

Kind code of ref document: C1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase in:

Ref country code: JP