Connect public, paid and private patent data with Google Patents Public Datasets

Medizinisches präparat zur behandlung von arthrose, arthritis und anderen rheumatischen gelenkerkrankungen

Info

Publication number
WO2001013949A3
WO2001013949A3 PCT/DE2000/002720 DE0002720W WO2001013949A3 WO 2001013949 A3 WO2001013949 A3 WO 2001013949A3 DE 0002720 W DE0002720 W DE 0002720W WO 2001013949 A3 WO2001013949 A3 WO 2001013949A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
joint
preparation
shell
groups
shelled
Prior art date
Application number
PCT/DE2000/002720
Other languages
English (en)
French (fr)
Other versions
WO2001013949A2 (de )
Inventor
Andreas Jordan
Original Assignee
Magforce Applic Gmbh
Andreas Jordan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation; Therapies using these preparations
    • A61K41/0052Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S514/00Drug, bio-affecting and body treating compositions
    • Y10S514/825Arthritis

Abstract

Ein medizinisches Präparat zur Behandlung von Arthrose, Arthritis und rheumatischen Erkrankungen umfaßt eine Suspension aus ein- oder mehrschaligen nanoskaligen Teilchen, die jeweils aus einem eisenoxidhaltigen Kern und einer inneren Schale mit zur Bildung von kationischen Gruppen befähigten Gruppen bzw. Wahlweise mindestens einer äußeren Schale mit neutralen und/oder anionischen Gruppen bestehen. An die innere Schale sind Radionuklide und unter Wärmeeinfluß zytotoxisch wirkende Stoffe gebunden. Das in den Gelenkspalt injizierte und einem magnetischen Wechselfeld ausgesetzte Präparat verspricht aufgrund der hohen Phagozytoserate und der trimodalen kombinatorischen Wirkung von Thermo-, Radio- und Chemotherapie einen hervorragenden Therapieerfolg.
PCT/DE2000/002720 1999-08-19 2000-08-09 Medizinisches präparat zur behandlung von arthrose, arthritis und anderen rheumatischen gelenkerkrankungen WO2001013949A3 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE1999140220 DE19940220B4 (de) 1999-08-19 1999-08-19 Medizinisches Präparat zur Behandlung von Arthrose, Arthritis und anderen rheumatischen Gelenkerkrankungen
DE19940220.5 1999-08-19

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2001518085A JP2003507434A (ja) 1999-08-19 2000-08-09 関節症、関節炎、及び他のリウマチ性関節疾患を治療するための医療用調製物
DE2000511033 DE50011033D1 (de) 1999-08-19 2000-08-09 Medizinisches präparat zur behandlung von arthrose, arthritis und anderen rheumatischen gelenkerkrankungen
US10048037 US6669623B1 (en) 1999-08-19 2000-08-09 Medical preparation for treating arthrosis, arthritis and other rheumatic joint diseases
EP20000967511 EP1204426B1 (de) 1999-08-19 2000-08-09 Medizinisches präparat zur behandlung von arthrose, arthritis und anderen rheumatischen gelenkerkrankungen

Publications (2)

Publication Number Publication Date
WO2001013949A2 true WO2001013949A2 (de) 2001-03-01
WO2001013949A3 true true WO2001013949A3 (de) 2001-12-20

Family

ID=7919494

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2000/002720 WO2001013949A3 (de) 1999-08-19 2000-08-09 Medizinisches präparat zur behandlung von arthrose, arthritis und anderen rheumatischen gelenkerkrankungen

Country Status (6)

Country Link
US (1) US6669623B1 (de)
JP (1) JP2003507434A (de)
DE (1) DE19940220B4 (de)
EP (1) EP1204426B1 (de)
ES (1) ES2249297T3 (de)
WO (1) WO2001013949A3 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7951061B2 (en) * 2001-07-25 2011-05-31 Allan Foreman Devices for targeted delivery of thermotherapy, and methods related thereto
US7731648B2 (en) * 2001-07-25 2010-06-08 Aduro Biotech Magnetic nanoscale particle compositions, and therapeutic methods related thereto
WO2003022308A3 (en) * 2001-09-13 2003-05-30 Scient Generics Ltd Therapeutic insert and therapeutic method
CA2469335A1 (en) * 2002-02-04 2003-12-31 Nanophase Technologies Corporation Stable dispersions of nanoparticles in aqueous media
DE102005039579A1 (de) * 2005-08-19 2007-02-22 Magforce Nanotechnologies Ag Verfahren zur Einschleusung von therapeutischen Substanzen in Zellen
US20080281386A1 (en) * 2007-05-09 2008-11-13 Tessaron Medical, Inc. Systems and methods for treating body tissue
US20080281318A1 (en) * 2007-05-09 2008-11-13 Tessaron Medical, Inc. Systems and methods for inductive heat treatment of body tissue
US20090157069A1 (en) * 2007-12-06 2009-06-18 Curtis Tom Systems and methods for thermal treatment of body tissue
DE102009058650A1 (de) 2009-12-16 2011-06-22 Leibniz-Institut für Neue Materialien gemeinnützige GmbH, 66123 Magnetische Kompositpartikel
EP2558108A1 (de) * 2010-04-12 2013-02-20 Ramot at Tel-Aviv University Ltd Eisenoxidnanopartikel zur verwendung bei der behandlung von nicht infektiösen entzündungserkrankungen
DK2683440T3 (da) 2011-03-10 2016-02-08 Magforce Ag Computerstøttet simulationsværktøj til understøttelse ved planlægning af en termoterapi
JP5844902B2 (ja) 2011-08-10 2016-01-20 マグフォース アーゲー アルコキシシランでコーティングされた磁性ナノ粒子の凝集化
DE102012213839B4 (de) * 2012-08-03 2017-06-14 Leibniz-Institut Für Festkörper- Und Werkstoffforschung Dresden E.V. Verfahren zur kontrollierten Bewegung von Objekten in flüssigen Medien

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758429A (en) * 1985-11-04 1988-07-19 Gordon Robert T Method for the treatment of arthritis and inflammatory joint diseases
US5149319A (en) * 1990-09-11 1992-09-22 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids
DE19726282A1 (de) * 1997-06-20 1998-12-24 Inst Neue Mat Gemein Gmbh Nanoskalige Teilchen mit einem von mindestens zwei Schalen umgebenen eisenoxid-haltigen Kern

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4303636A (en) * 1974-08-20 1981-12-01 Gordon Robert T Cancer treatment
US4590922A (en) * 1983-08-19 1986-05-27 Gordon Robert T Use of ferromagnetic, paramagnetic and diamagnetic particles in the treatment of infectious diseases
US5655546A (en) * 1995-06-07 1997-08-12 Halpern; Alan A. Method for cartilage repair
DE19716732C2 (de) * 1997-03-07 1999-03-25 Max Delbrueck Centrum Spezifische Magnetosomen, Verfahren zu ihrer Herstellung und ihre Verwendung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758429A (en) * 1985-11-04 1988-07-19 Gordon Robert T Method for the treatment of arthritis and inflammatory joint diseases
US5149319A (en) * 1990-09-11 1992-09-22 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids
DE19726282A1 (de) * 1997-06-20 1998-12-24 Inst Neue Mat Gemein Gmbh Nanoskalige Teilchen mit einem von mindestens zwei Schalen umgebenen eisenoxid-haltigen Kern

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; MASAI, AKIRA: "Development of Anticancer-Agent-Releasing Microcapsules for Chemotherapy Combined with Embolo- Hyperthermic Therapy.", XP002174710, retrieved from STN Database accession no. PREV199598223481 *
GRADY E.D. ET AL: "Combination of internal radiation therapy and hyperthermia to treat liver cancer.", SOUTHERN MEDICAL JOURNAL, (1983) 76/9 (1101-1105). CODEN: SMJOAV, XP001015654 *
NIPPON ACTA RADIOLOGICA, (1995) VOL. 55, NO. 1, PP. 50-57. *

Also Published As

Publication number Publication date Type
US6669623B1 (en) 2003-12-30 grant
JP2003507434A (ja) 2003-02-25 application
DE19940220A1 (de) 2001-02-22 application
EP1204426B1 (de) 2005-08-24 grant
WO2001013949A2 (de) 2001-03-01 application
ES2249297T3 (es) 2006-04-01 grant
DE19940220B4 (de) 2007-05-03 grant
EP1204426A2 (de) 2002-05-15 application

Similar Documents

Publication Publication Date Title
Stolte et al. Healing gastric MALT lymphomas by eradicating H pylori?
Hou et al. The in vivo performance of biomagnetic hydroxyapatite nanoparticles in cancer hyperthermia therapy
Macdonald et al. Postoperative combined radiation and chemotherapy improves disease-free survival (DFS) and overall survival (OS) in resected adenocarcinoma of the stomach and GE junction. Results of Intergroup Study INT-0116 (SWOG 9008)
Phillips et al. Efficacy and safety of fluvoxamine in body dysmorphic disorder.
US6167313A (en) Targeted hysteresis hyperthermia as a method for treating diseased tissue
Cummings et al. The treatment of glomus tumors in the temporal bone by megavoltage radiation
US4983159A (en) Inductive heating process for use in causing necrosis of neoplasms at selective frequencies
Silberstein et al. Overview of diagnosis and treatment of migraine.
Mornet et al. Magnetic nanoparticle design for medical diagnosis and therapy
US4359453A (en) Atherosclerosis treatment method
US20050271745A1 (en) Magnetic nanoparticle compositions, and methods related thereto
US20050090732A1 (en) Therapy via targeted delivery of nanoscale particles
Babincova et al. AC-magnetic field controlled drug release from magnetoliposomes: design of a method for site-specific chemotherapy
Salazar et al. Single‐dose half‐body irradiation for palliation of multiple bone metastases from solid tumors: Final radiation therapy oncology group report
Shinkai et al. Intracellular hyperthermia for cancer using magnetite cationic liposomes
DE3218121A1 (de) Arzneimittel zur tumorbehandlung
US7612032B2 (en) Method for treating oncological diseases
US5651989A (en) Magnetically responsive composition for carrying biologically active substances and methods of production and use
WO1999027911A1 (en) Soft-pellet drug and process for the preparation thereof
US20060142749A1 (en) Magnetic nanoscale particle compositions, and therapeutic methods related thereto
Garakani et al. Treatment of panic disorder with imipramine alone.
Chen et al. Analysis of magnetic drug carrier particle capture by a magnetizable intravascular stent: 1. Parametric study with single wire correlation
Kolosnjaj-Tabi et al. Heat-generating iron oxide nanocubes: subtle “destructurators” of the tumoral microenvironment
WO2004013172A3 (en) Fragments of beta-amyloid as targets for vaccination against alzheimer disease
Wang et al. Histologic study of effects of radiation synovectomy with Rhenium-188 microsphere

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AU BA BB BG BR BZ CA CN CR CU CZ DM DZ EE GD GE HR HU ID IL IN IS JP KP KR LC LK LR LT LV MA MD MG MK MN MX NO NZ PL RO SG SI SK TR TT UA US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2000967511

Country of ref document: EP

AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AU BA BB BG BR BZ CA CN CR CU CZ DM DZ EE GD GE HR HU ID IL IN IS JP KP KR LC LK LR LT LV MA MD MG MK MN MX NO NZ PL RO SG SI SK TR TT UA US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 10048037

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 2000967511

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 2000967511

Country of ref document: EP