WO2001013906A3 - Compositions including modafinil for treatment of eating disorders and for appetite stimulation - Google Patents

Compositions including modafinil for treatment of eating disorders and for appetite stimulation Download PDF

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Publication number
WO2001013906A3
WO2001013906A3 PCT/US2000/022796 US0022796W WO0113906A3 WO 2001013906 A3 WO2001013906 A3 WO 2001013906A3 US 0022796 W US0022796 W US 0022796W WO 0113906 A3 WO0113906 A3 WO 0113906A3
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
eating disorders
compositions including
appetite stimulation
modafinil
Prior art date
Application number
PCT/US2000/022796
Other languages
French (fr)
Other versions
WO2001013906A2 (en
Inventor
Matthew S Miller
Thomas E Scammell
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Priority to CA002382220A priority Critical patent/CA2382220A1/en
Priority to MXPA02001790A priority patent/MXPA02001790A/en
Priority to AU69191/00A priority patent/AU6919100A/en
Priority to EP00957594A priority patent/EP1210074A2/en
Priority to JP2001518044A priority patent/JP2003522132A/en
Publication of WO2001013906A2 publication Critical patent/WO2001013906A2/en
Publication of WO2001013906A3 publication Critical patent/WO2001013906A3/en
Priority to HK02108793.0A priority patent/HK1047053A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Modafinil is effective in improving symptoms of eating disorders or in stimulating appetite.
PCT/US2000/022796 1999-08-20 2000-08-18 Compositions including modafinil for treatment of eating disorders and for appetite stimulation WO2001013906A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA002382220A CA2382220A1 (en) 1999-08-20 2000-08-18 Compositions including modafinil for treatment of eating disorders and for appetite stimulation
MXPA02001790A MXPA02001790A (en) 1999-08-20 2000-08-18 Compositions including modafinil for treatment of eating disorders and for appetite stimulation.
AU69191/00A AU6919100A (en) 1999-08-20 2000-08-18 Compositions including modafinil for treatment of eating disorders and for appetite stimulation
EP00957594A EP1210074A2 (en) 1999-08-20 2000-08-18 Compositions including modafinil for treatment of eating disorders and for appetite stimulation
JP2001518044A JP2003522132A (en) 1999-08-20 2000-08-18 Composition comprising modafinil for treatment of eating disorders and appetite stimulation
HK02108793.0A HK1047053A1 (en) 1999-08-20 2002-12-03 Compositions including modafinil for treatment of eating disorders and for appetite stimulation

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15007199P 1999-08-20 1999-08-20
US60/150,071 1999-08-20
US09/640,824 US6455588B1 (en) 1999-08-20 2000-08-17 Compositions including modafinil for treatment of eating disorders and for appetite stimulation
US09/640,824 2001-10-10

Publications (2)

Publication Number Publication Date
WO2001013906A2 WO2001013906A2 (en) 2001-03-01
WO2001013906A3 true WO2001013906A3 (en) 2001-09-13

Family

ID=26847297

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/022796 WO2001013906A2 (en) 1999-08-20 2000-08-18 Compositions including modafinil for treatment of eating disorders and for appetite stimulation

Country Status (8)

Country Link
US (2) US6455588B1 (en)
EP (1) EP1210074A2 (en)
JP (1) JP2003522132A (en)
AU (1) AU6919100A (en)
CA (1) CA2382220A1 (en)
HK (1) HK1047053A1 (en)
MX (1) MXPA02001790A (en)
WO (1) WO2001013906A2 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ2003529A3 (en) * 2000-07-27 2003-09-17 Teva Pharmaceutical Industries Ltd. Crystalline and pure modafinil and process for preparing thereof
US6919378B2 (en) * 2000-10-11 2005-07-19 Cephalon, Inc. Pharmaceutical solutions of modafinil compounds
US7704975B2 (en) * 2000-12-19 2010-04-27 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US7141555B2 (en) * 2000-12-19 2006-11-28 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
IL158959A (en) * 2001-05-25 2010-06-30 Cephalon Inc Solid pharmaceutical formulations comprising modafinil
US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
US7229644B2 (en) * 2002-05-23 2007-06-12 Cephalon, Inc. Pharmaceutical formulations of modafinil
US20040048931A1 (en) 2002-07-12 2004-03-11 Craig Heacock Modafinil pharmaceutical compositions
US6992219B2 (en) 2002-08-09 2006-01-31 Cephalon France Modafinil polymorphic forms
US20040116532A1 (en) * 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
US20040253308A1 (en) * 2003-04-29 2004-12-16 Barr Laboratories, Inc. Surface-treated modafinil particles
AR045423A1 (en) * 2003-05-13 2005-10-26 Cephalon Inc COMBINATIONS OF ANALYTICS AND ANTIDEPRESSANTS
US7368591B2 (en) 2003-09-19 2008-05-06 Cephalon France Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
US20050137264A1 (en) * 2003-12-22 2005-06-23 Patel Ashish A. Modafinil compositions
EP1586560A1 (en) * 2004-04-13 2005-10-19 Cephalon, Inc. Thio-substituted arylmethanesulfinyl derivatives
US7119214B2 (en) * 2004-04-13 2006-10-10 Cephalon France Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives
US7297817B2 (en) * 2004-04-13 2007-11-20 Cephalon France Thio-substituted arylmethanesulfinyl derivatives
US7314875B2 (en) * 2004-04-13 2008-01-01 Cephalon, Inc. Tricyclic aromatic and bis-phenyl sulfinyl derivatives
US7423176B2 (en) * 2004-04-13 2008-09-09 Cephalon, Inc. Bicyclic aromatic sulfinyl derivatives
US7449481B2 (en) * 2004-04-13 2008-11-11 Cephalon, Inc. Thio-substituted biaryl-methanesulfinyl derivatives
US20060024370A1 (en) * 2004-07-29 2006-02-02 Cephalon France Modafinil oral lyophilizate
GB2427137A (en) * 2005-06-16 2006-12-20 Sunita Kanji Shingdia Use of modafinil in appetite suppression
US8536120B2 (en) * 2006-04-28 2013-09-17 The Administrators Of The Tulane Educational Fund Ghrelin/growth hormone releasing peptide/growth hormone secretatogue receptor antagonists and uses thereof
KR20090031618A (en) * 2006-07-12 2009-03-26 엘란 코포레이션, 피엘씨 Nanoparticulate formulations of modafinil
US20080181966A1 (en) * 2006-10-18 2008-07-31 Cephalon, Inc. Modafinil pharmaceutical compositions
AU2008297535A1 (en) * 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of fibronectin fragment (196-203 ) as a therapeutic agent
US20090325999A1 (en) * 2008-06-27 2009-12-31 Jie Du Personalized pharmaceutical kits, packaging and compositions for the treatment of allergic conditions
EP2238973A1 (en) 2009-04-07 2010-10-13 Cephalon France Lyophilized preparations of proteasome inhibitors
US9724381B2 (en) 2009-05-12 2017-08-08 The Administrators Of The Tulane Educational Fund Methods of inhibiting the ghrelin/growth hormone secretatogue receptor pathway and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001333A1 (en) * 1993-06-30 1995-01-12 Laboratoire L. Lafon Acetamide derivatives and their use for modifying feeding behaviour modifiers
WO1995001171A1 (en) * 1993-06-30 1995-01-12 Laboratoire L. Lafon Use of acetamide derivatives for modifying feeding behaviour
US5810745A (en) * 1994-09-19 1998-09-22 Chaffringeon; Bernard Single-use body fluid analysis device

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1584462A (en) 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
FR2593809B1 (en) 1986-01-31 1988-07-22 Lafon Labor BENZHYDRYLSULFINYLACETAMIDE, PROCESS FOR PREPARATION AND THERAPEUTIC USE
FR2663225B1 (en) 1990-06-14 1994-11-04 Lafon Labor NEW USE OF MODAFINIL.
US5618845A (en) 1994-10-06 1997-04-08 Cephalon, Inc. Acetamide derivative having defined particle size
FR2771004B1 (en) 1997-11-19 2000-02-18 Inst Curie USE OF BENZHYDRYL SULFINYL DERIVATIVES FOR THE MANUFACTURE OF MEDICINAL PRODUCTS HAVING A WAKING EFFECT IN SITUATIONS OF DRUG-BASED VIGILANCE DISORDERS

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001333A1 (en) * 1993-06-30 1995-01-12 Laboratoire L. Lafon Acetamide derivatives and their use for modifying feeding behaviour modifiers
WO1995001171A1 (en) * 1993-06-30 1995-01-12 Laboratoire L. Lafon Use of acetamide derivatives for modifying feeding behaviour
US5810745A (en) * 1994-09-19 1998-09-22 Chaffringeon; Bernard Single-use body fluid analysis device

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FARINA B. ET AL: "[Imaging of the breast nodule]. NUOVE PROSPETTIVE NELLA DIAGNOSI E NELLA TERAPIA DELLA NARCOLESSIA.", CLINICA TERAPEUTICA, (2000) 151/5 (357-363)., XP000989666 *
NICOLAIDIS STYLIANOS ET AL: "Nonamphetamine awakening agent modafinil induces feeding changes in the rat.", BRAIN RESEARCH BULLETIN, vol. 32, no. 2, 1993, pages 87 - 90, XP000989669, ISSN: 0361-9230 *

Also Published As

Publication number Publication date
AU6919100A (en) 2001-03-19
MXPA02001790A (en) 2003-07-14
EP1210074A2 (en) 2002-06-05
HK1047053A1 (en) 2003-02-07
US20020128322A1 (en) 2002-09-12
JP2003522132A (en) 2003-07-22
CA2382220A1 (en) 2001-03-01
WO2001013906A2 (en) 2001-03-01
US6455588B1 (en) 2002-09-24

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