WO2001010375A3 - Inhibition of action potentials - Google Patents

Inhibition of action potentials Download PDF

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Publication number
WO2001010375A3
WO2001010375A3 PCT/IL2000/000467 IL0000467W WO0110375A3 WO 2001010375 A3 WO2001010375 A3 WO 2001010375A3 IL 0000467 W IL0000467 W IL 0000467W WO 0110375 A3 WO0110375 A3 WO 0110375A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
nervous tissue
inhibition
action potentials
action potential
electrical energy
Prior art date
Application number
PCT/IL2000/000467
Other languages
French (fr)
Other versions
WO2001010375A2 (en )
Inventor
Bella Felsen
Nissim Darvish
Daniel Goldenholz
Original Assignee
Impulse Dynamics Nv
Bella Felsen
Nissim Darvish
Daniel Goldenholz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071Pain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36003Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of motor muscles, e.g. for walking assistance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3601Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of respiratory organs

Abstract

Apparatus (20) for modifying the electrical behavior of nervous tissue (30) in a human subject is provided. At least one inhibiting electrode (22) is placed in a vicinity of the subject's nervous tissue, and a control unit (40) drives the at least one inhibiting electrode to apply electrical energy to the nervous tissue to inhibit propagation therein of an action potential. Preferably, application of the electrical energy substantially does not cause generation of an action potential in at least a portion of the nervous tissue.
PCT/IL2000/000467 1999-08-04 2000-08-03 Inhibition of action potentials WO2001010375A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US36812499 true 1999-08-04 1999-08-04
US09/368,124 1999-08-04

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AU6465400A AU6465400A (en) 1999-08-04 2000-08-03 Inhibition of action potentials

Publications (2)

Publication Number Publication Date
WO2001010375A2 true WO2001010375A2 (en) 2001-02-15
WO2001010375A3 true true WO2001010375A3 (en) 2001-08-16

Family

ID=23449949

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2000/000467 WO2001010375A3 (en) 1999-08-04 2000-08-03 Inhibition of action potentials

Country Status (1)

Country Link
WO (1) WO2001010375A3 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8880192B2 (en) 2012-04-02 2014-11-04 Bio Control Medical (B.C.M.) Ltd. Electrode cuffs
US9101765B2 (en) 1999-03-05 2015-08-11 Metacure Limited Non-immediate effects of therapy
US9186504B2 (en) 2010-11-15 2015-11-17 Rainbow Medical Ltd Sleep apnea treatment
US9265930B2 (en) 1997-07-16 2016-02-23 Metacure Limited Methods and devices for modifying vascular parameters
US9457186B2 (en) 2010-11-15 2016-10-04 Bluewind Medical Ltd. Bilateral feedback
US9597521B2 (en) 2015-01-21 2017-03-21 Bluewind Medical Ltd. Transmitting coils for neurostimulation

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6600954B2 (en) 2001-01-25 2003-07-29 Biocontrol Medical Bcm Ltd. Method and apparatus for selective control of nerve fibers
US6892098B2 (en) 2001-04-26 2005-05-10 Biocontrol Medical Ltd. Nerve stimulation for treating spasticity, tremor, muscle weakness, and other motor disorders
US6684105B2 (en) 2001-08-31 2004-01-27 Biocontrol Medical, Ltd. Treatment of disorders by unidirectional nerve stimulation
US6907295B2 (en) 2001-08-31 2005-06-14 Biocontrol Medical Ltd. Electrode assembly for nerve control
US8116881B2 (en) 2004-06-10 2012-02-14 Bio Control Medical (B.C.M.) Ltd Electrode assembly for nerve control
US7551599B2 (en) 2004-03-29 2009-06-23 Corrigent Systems Ltd. Layer-3 network routing with RPR layer-2 visibility
US7627384B2 (en) 2004-11-15 2009-12-01 Bio Control Medical (B.C.M.) Ltd. Techniques for nerve stimulation
US8265758B2 (en) 2005-03-24 2012-09-11 Metacure Limited Wireless leads for gastrointestinal tract applications
US7974202B2 (en) 2005-05-06 2011-07-05 Corrigent Systems, Ltd. Tunnel provisioning with link aggregation
WO2007017842A3 (en) 2005-08-09 2008-12-18 Tylerton Internat Inc Satiety
US7545740B2 (en) 2006-04-07 2009-06-09 Corrigent Systems Ltd. Two-way link aggregation
US7904176B2 (en) 2006-09-07 2011-03-08 Bio Control Medical (B.C.M.) Ltd. Techniques for reducing pain associated with nerve stimulation
US8423130B2 (en) 2008-05-09 2013-04-16 Metacure Limited Optimization of thresholds for eating detection
US20100010603A1 (en) 2008-07-09 2010-01-14 Tamir Ben-David Electrode cuffs
WO2014087337A1 (en) 2012-12-06 2014-06-12 Bluewind Medical Ltd. Delivery of implantable neurostimulators
US9370660B2 (en) 2013-03-29 2016-06-21 Rainbow Medical Ltd. Independently-controlled bidirectional nerve stimulation
US9764146B2 (en) 2015-01-21 2017-09-19 Bluewind Medical Ltd. Extracorporeal implant controllers
US10004896B2 (en) 2015-01-21 2018-06-26 Bluewind Medical Ltd. Anchors and implant devices
US9782589B2 (en) 2015-06-10 2017-10-10 Bluewind Medical Ltd. Implantable electrostimulator for improving blood flow
US10105540B2 (en) 2015-11-09 2018-10-23 Bluewind Medical Ltd. Optimization of application of current
US9713707B2 (en) 2015-11-12 2017-07-25 Bluewind Medical Ltd. Inhibition of implant migration
US10124178B2 (en) 2016-11-23 2018-11-13 Bluewind Medical Ltd. Implant and delivery tool therefor

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608985A (en) * 1984-10-11 1986-09-02 Case Western Reserve University Antidromic pulse generating wave form for collision blocking
US5178161A (en) * 1988-09-02 1993-01-12 The Board Of Trustees Of The Leland Stanford Junior University Microelectronic interface
US5330515A (en) * 1992-06-17 1994-07-19 Cyberonics, Inc. Treatment of pain by vagal afferent stimulation
US5702429A (en) * 1996-04-04 1997-12-30 Medtronic, Inc. Neural stimulation techniques with feedback
US5716377A (en) * 1996-04-25 1998-02-10 Medtronic, Inc. Method of treating movement disorders by brain stimulation
US5755750A (en) * 1995-11-13 1998-05-26 University Of Florida Method and apparatus for selectively inhibiting activity in nerve fibers
US5792186A (en) * 1996-04-25 1998-08-11 Medtronic, Inc. Method and apparatus for treating neurodegenerative disorders by electrical brain stimulation
WO1999003533A1 (en) * 1997-07-16 1999-01-28 Impulse Dynamics (Israel) Ltd. Smooth muscle controller

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4784142A (en) 1984-01-09 1988-11-15 Pain Suppression Labs, Inc. Methodology for electronic dental analgesia
US5312321A (en) 1986-11-21 1994-05-17 Holcomb Technology, Inc. Method and apparatus for suppressing neuron action potential firings
US5018525A (en) 1989-11-01 1991-05-28 Kharkovski Medicinsky Institute Device for dental electroanalgesia
US5203326A (en) 1991-12-18 1993-04-20 Telectronics Pacing Systems, Inc. Antiarrhythmia pacer using antiarrhythmia pacing and autonomic nerve stimulation therapy
US5324317A (en) 1992-09-30 1994-06-28 Medserve Group, Inc. Interferential stimulator for applying low frequency alternating current to the body
US5713923A (en) 1996-05-13 1998-02-03 Medtronic, Inc. Techniques for treating epilepsy by brain stimulation and drug infusion

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608985A (en) * 1984-10-11 1986-09-02 Case Western Reserve University Antidromic pulse generating wave form for collision blocking
US5178161A (en) * 1988-09-02 1993-01-12 The Board Of Trustees Of The Leland Stanford Junior University Microelectronic interface
US5330515A (en) * 1992-06-17 1994-07-19 Cyberonics, Inc. Treatment of pain by vagal afferent stimulation
US5755750A (en) * 1995-11-13 1998-05-26 University Of Florida Method and apparatus for selectively inhibiting activity in nerve fibers
US5702429A (en) * 1996-04-04 1997-12-30 Medtronic, Inc. Neural stimulation techniques with feedback
US5716377A (en) * 1996-04-25 1998-02-10 Medtronic, Inc. Method of treating movement disorders by brain stimulation
US5792186A (en) * 1996-04-25 1998-08-11 Medtronic, Inc. Method and apparatus for treating neurodegenerative disorders by electrical brain stimulation
WO1999003533A1 (en) * 1997-07-16 1999-01-28 Impulse Dynamics (Israel) Ltd. Smooth muscle controller

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9265930B2 (en) 1997-07-16 2016-02-23 Metacure Limited Methods and devices for modifying vascular parameters
US9101765B2 (en) 1999-03-05 2015-08-11 Metacure Limited Non-immediate effects of therapy
US9186504B2 (en) 2010-11-15 2015-11-17 Rainbow Medical Ltd Sleep apnea treatment
US9457186B2 (en) 2010-11-15 2016-10-04 Bluewind Medical Ltd. Bilateral feedback
US8880192B2 (en) 2012-04-02 2014-11-04 Bio Control Medical (B.C.M.) Ltd. Electrode cuffs
US9597521B2 (en) 2015-01-21 2017-03-21 Bluewind Medical Ltd. Transmitting coils for neurostimulation

Also Published As

Publication number Publication date Type
WO2001010375A2 (en) 2001-02-15 application

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