WO2000044398A3 - Methods for increasing circulating platelets for collection and cryopreservation using thrombopoietin compositions - Google Patents
Methods for increasing circulating platelets for collection and cryopreservation using thrombopoietin compositions Download PDFInfo
- Publication number
- WO2000044398A3 WO2000044398A3 PCT/US2000/002173 US0002173W WO0044398A3 WO 2000044398 A3 WO2000044398 A3 WO 2000044398A3 US 0002173 W US0002173 W US 0002173W WO 0044398 A3 WO0044398 A3 WO 0044398A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cryopreservation
- thrombopoietin
- compositions
- collection
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/196—Thrombopoietin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Silicon Compounds (AREA)
- Curing Cements, Concrete, And Artificial Stone (AREA)
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE60006487T DE60006487T2 (en) | 1999-01-28 | 2000-01-28 | INCREASING CIRCULATING TILES WITH THROMBOPOIETINE COMPOSITIONS |
AT00913278T ATE253935T1 (en) | 1999-01-28 | 2000-01-28 | INCREASING CIRCULATIVE PLATELETS WITH THROMBOPOIETIN COMPOSITIONS |
EP00913278A EP1146895B1 (en) | 1999-01-28 | 2000-01-28 | Thrombopoietin compositions for increasing circulating platelets |
CA002361260A CA2361260A1 (en) | 1999-01-28 | 2000-01-28 | Methods for increasing circulating platelets for collection and cryopreservation using thrombopoietin compositions |
JP2000595700A JP2002535373A (en) | 1999-01-28 | 2000-01-28 | Methods for increasing circulating platelets for collection and cryopreservation using thrombopoietin compositions |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23944299A | 1999-01-28 | 1999-01-28 | |
US09/239,442 | 1999-01-28 | ||
US24437099A | 1999-02-04 | 1999-02-04 | |
US09/244,370 | 1999-02-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000044398A2 WO2000044398A2 (en) | 2000-08-03 |
WO2000044398A3 true WO2000044398A3 (en) | 2001-03-15 |
Family
ID=26932577
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/002173 WO2000044398A2 (en) | 1999-01-28 | 2000-01-28 | Methods for increasing circulating platelets for collection and cryopreservation using thrombopoietin compositions |
Country Status (6)
Country | Link |
---|---|
EP (2) | EP1146895B1 (en) |
JP (1) | JP2002535373A (en) |
AT (1) | ATE253935T1 (en) |
CA (1) | CA2361260A1 (en) |
DE (1) | DE60006487T2 (en) |
WO (1) | WO2000044398A2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8834402B2 (en) | 2009-03-12 | 2014-09-16 | Haemonetics Corporation | System and method for the re-anticoagulation of platelet rich plasma |
US9302042B2 (en) | 2010-12-30 | 2016-04-05 | Haemonetics Corporation | System and method for collecting platelets and anticipating plasma return |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1542714T3 (en) * | 2002-09-18 | 2014-05-26 | Janssen Pharmaceuticals Inc | PROCEDURES FOR INCREASING PRODUCTION OF BLADETS AND HEMATOPOIETIC STEM CELLS |
JP2005187435A (en) * | 2003-12-26 | 2005-07-14 | Otsuka Chemical Co Ltd | Thrombocyte production promoting composition |
WO2007044982A2 (en) * | 2005-10-13 | 2007-04-19 | Smithkline Beecham Corporation | Methods for the preservation of platelet efficacy during storage |
EP2881127B1 (en) | 2010-11-05 | 2017-01-04 | Haemonetics Corporation | System and method for automated platelet wash |
US20150148385A1 (en) | 2012-06-29 | 2015-05-28 | Shionogi & Co., Ltd. | Pharmaceutical composition containing a compound having a thrombopoietin receptor agonistic activity |
JP6875619B2 (en) * | 2015-02-26 | 2021-05-26 | 株式会社細胞応用技術研究所 | How to store platelet-rich plasma |
JP6168579B1 (en) * | 2016-02-12 | 2017-07-26 | 塩野義製薬株式会社 | Platelet production promoter containing Rustrombopag for patients with severe liver dysfunction |
IL266723B2 (en) | 2016-11-18 | 2023-10-01 | Power Of Platelets Pte Ltd | A method for preparing a growth factors containing platelet releasate |
EP3829604A4 (en) * | 2018-07-27 | 2022-04-27 | Cellphire Inc. | Cryopreserved platelet compositions and methods for making |
EP3886879A4 (en) | 2018-11-30 | 2022-12-07 | Cellphire Inc. | Platelets as delivery agents |
EP3887402A4 (en) | 2018-11-30 | 2022-10-26 | Cellphire, Inc. | Platelets as delivery agents |
AU2020267368B2 (en) | 2019-05-03 | 2023-05-04 | Cellphire, Inc. | Materials and methods for producing blood products |
US20210308066A1 (en) | 2020-02-04 | 2021-10-07 | Cellphire, Inc. | Anti-fibrinolytic loaded platelets |
CN114450066A (en) | 2019-08-16 | 2022-05-06 | 塞尔菲乐有限公司 | Thrombosomes as antiplatelet agent reversal agents |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998052598A1 (en) * | 1997-05-21 | 1998-11-26 | Genentech, Inc. | Novel administration of thrombopoietin |
-
2000
- 2000-01-28 EP EP00913278A patent/EP1146895B1/en not_active Revoked
- 2000-01-28 AT AT00913278T patent/ATE253935T1/en not_active IP Right Cessation
- 2000-01-28 DE DE60006487T patent/DE60006487T2/en not_active Revoked
- 2000-01-28 EP EP03021505A patent/EP1374890A3/en not_active Withdrawn
- 2000-01-28 JP JP2000595700A patent/JP2002535373A/en not_active Withdrawn
- 2000-01-28 WO PCT/US2000/002173 patent/WO2000044398A2/en not_active Application Discontinuation
- 2000-01-28 CA CA002361260A patent/CA2361260A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998052598A1 (en) * | 1997-05-21 | 1998-11-26 | Genentech, Inc. | Novel administration of thrombopoietin |
Non-Patent Citations (4)
Title |
---|
VADHAN-RAJ S ET AL: "Enhanced retention of in vitro functional activity of rhTPO-induced platelets following cryopreservation with ThrombosolTM and 2 percent DMSO.", BLOOD, vol. 90, no. 10 SUPPL. 1 PART 1, 15 November 1997 (1997-11-15), 39th Annual Meeting of the American Society of Hematology;San Diego, California, USA; December 5-9, 1997, pages 38A, XP000939382, ISSN: 0006-4971 * |
VADHAN-RAJ SAROJ ET AL: "Enhanced retention of in vitro functional activity of platelets from recombinant human thrombopoietin-treated patients following long-term cryopreservation with a platelet-preserving solution (ThromboSol) and 2% DMSO.", BRITISH JOURNAL OF HAEMATOLOGY, vol. 104, no. 2, February 1999 (1999-02-01), pages 403 - 411, XP000939372, ISSN: 0007-1048 * |
VADHAN-RAJ SAROJ: "Recombinant human thrombopoietin: Clinical experience and in vivo biology.", SEMINARS IN HEMATOLOGY, vol. 35, no. 3, July 1998 (1998-07-01), pages 261 - 268, XP000939399, ISSN: 0037-1963 * |
VAN DE VEN CARMELLA ET AL: "The haemopoietic effects of thrombopoietin administered post-myelosuppressive carboplatin therapy compared to either pre- and post- or pre-chemotherapy.", BRITISH JOURNAL OF HAEMATOLOGY, vol. 102, no. 3, August 1998 (1998-08-01), pages 775 - 782, XP000939371, ISSN: 0007-1048 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8834402B2 (en) | 2009-03-12 | 2014-09-16 | Haemonetics Corporation | System and method for the re-anticoagulation of platelet rich plasma |
US9248227B2 (en) | 2009-03-12 | 2016-02-02 | Haemonetics Corporation | System and method for the re-anticoagulation of platelet rich plasma |
US9302042B2 (en) | 2010-12-30 | 2016-04-05 | Haemonetics Corporation | System and method for collecting platelets and anticipating plasma return |
Also Published As
Publication number | Publication date |
---|---|
DE60006487T2 (en) | 2004-09-09 |
JP2002535373A (en) | 2002-10-22 |
EP1374890A2 (en) | 2004-01-02 |
EP1146895A2 (en) | 2001-10-24 |
CA2361260A1 (en) | 2000-08-03 |
ATE253935T1 (en) | 2003-11-15 |
WO2000044398A2 (en) | 2000-08-03 |
DE60006487D1 (en) | 2003-12-18 |
EP1146895B1 (en) | 2003-11-12 |
EP1374890A3 (en) | 2004-08-25 |
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