WO2000035416A1 - Detergent composition - Google Patents
Detergent composition Download PDFInfo
- Publication number
- WO2000035416A1 WO2000035416A1 PCT/EP1999/009588 EP9909588W WO0035416A1 WO 2000035416 A1 WO2000035416 A1 WO 2000035416A1 EP 9909588 W EP9909588 W EP 9909588W WO 0035416 A1 WO0035416 A1 WO 0035416A1
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- WO
- WIPO (PCT)
- Prior art keywords
- composition
- composition according
- benefit agent
- cationic polymer
- cationic
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
- A61K8/0275—Containing agglomerated particulates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
- A61K8/585—Organosilicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/54—Polymers characterized by specific structures/properties
- A61K2800/542—Polymers characterized by specific structures/properties characterized by the charge
- A61K2800/5426—Polymers characterized by specific structures/properties characterized by the charge cationic
Definitions
- the present invention relates to detergent compositions suitable for topical application for cleansing and improving the condition of the human body, particularly for moisturising the skin, hair, nails and other epithelial tissues, including the mucosae.
- compositions which are formulated to give mild cleansing and conditioning of the skin, and improved deposition of benefit agents.
- compositions formulated to cleanse the skin are well known. It is also known to formulate products which provide both a cleansing and a moisturising benefit.
- WO 90/13283 discloses a composition comprising an acyl ester of an isethionic acid salt, a long chain fatty acid, a moisturiser component and, optionally, soap.
- an aqueous liquid cleansing and moisturising composition comprising: - a) a surface active agent selected from anionic, nonionic, zwitterionic and cationic, surface active agents, soap and mixtures thereof;
- the cationic polymer is present at levels of 0.05-3% by weight, and that the benefit agent is present in the neat composition as aggregated particles.
- compositions according to the invention are preferably shear thinning .
- compositions according to the present invention are that they lead to improved deposition of benefit agents from a surfactant containing aqueous liquid composition during use.
- compositions according to the invention that particles of the skin benefit agent form aggregates which comprise a number of individual particles.
- aggregates which characterise compositions according to the invention may typically comprise 5-5000 individual particles of benefit agent.
- compositions which comprise these aggregated particles, which aggregated particles stay in this form and do not coalesce serve to deliver to the substrate relatively large aggregates of benefit agent, which provides an effective local high concentration of the benefit agent, thus enhancing the moisturising benefit to the substrate, and also the overall efficiency of delivery of the benefit agent .
- compositions according to the invention may typically comprise relatively high populations of relatively large, aggregated particles.
- Compositions according to the invention may therefore for example have a mean individual particle size of less than 5 microns, typically less than 1 micron, but contain about 50% or less by weight of the benefit agent in the composition in particles less 3 microns in size.
- the composition may also comprise less than 10% by weight of the benefit agent in aggregated particles of greater than 80 microns in size.
- Compositions according to the invention typically have more than 3% by weight of the benefit agent in aggregated particles with sizes in the range 3-80 microns.
- compositions according to the invention also characteristically retain the aggregated microstructure during dilution in use, for example when diluted by a factor of 10 with distilled water. As such, compositions which have been diluted at ratios between 1:1 and 1:100 with water have been found also to retain the microstructure.
- compositions according to the invention in particular containing the aggregated particles described, preferably contain not only relatively high levels of benefit agent, cationic polymer, and contain aggregated particles of benefit agent, but may conveniently also be made according to preferred process aspects.
- the skin benefit agent should be prepared as a pre- emulsion, which is heated to 50-70°C.
- the surfactant components of the composition are prepared as a solution, and the skin benefit agent pre- emulsions from a) are blended into the surfactant solution.
- the cationic polymers are pre-dispersed in water in a controlled manner such that the rate of hydration of the cationic polymer is controlled if necessary. This can for example be done by dispersing the dried cationic polymer in a solution of pH at least 10, preferably greater than 11, to control hydration of the polymer, before dispersing it in the other components of the composition. Incomplete distribution of the cationic polymer is typified by a grainy appearance of the composition, or the presence of globules of undissolved polymer. Alternatively, the cationic polymer can be dispersed in a non-aqueous liquid component of the composition, such as eg glycerol .
- the non-aqueous component must be present in the composition at sufficient and suitable levels so as to provide satisfactory, non- lumpy dispersion of the cationic polymer which will disperse satisfactorily in the aqueous vehicle.
- the cationic polymer is fully dispersed in the aqueous vehicle prior to it being fully hydrated.
- the remaining components of the composition are blended together and maintained at or around 50-70°C.
- Complete mixing is preferably attained by subjecting the composition to high shear at this stage, but in such a manner that aeration of the composition is avoided; the high shear stage can typically take 20 minutes.
- the composition is cooled to 30°C where the minors (eg perfume, preservative) are added, and the viscosity is modified by the addition of the appropriate viscosity modifying agent .
- the minors eg perfume, preservative
- the cationic polymer used in compositions according to the invention is at least partially hydrated when it is dispersed in the aqueous vehicle. If the cationic polymer is insufficiently hydrated, this may lead to insufficient aggregation of the droplets of benefit agent in the composition, whilst if the cationic polymer is overly hydrated, in particular during its dispersion in the composition, it may prove difficult to disperse satisfactorily.
- composition according to the invention is suitable for cleansing and "moisturising", “conditioning” or
- the benefit agent is included in the composition to moisturise, condition and/or protect the skin.
- skin By “benefit agent” is meant a substance that softens the skin (stratum corneum) and keeps it soft by retarding the decrease of its water content and/or protects the skin.
- Preferred benefit agents which may be solid or liquid at room temperature, but for the sake of simplicity of terminology herein are referred to as "particles”, include:
- silicone oils, gums and modifications thereof such as linear and cyclic polydimethylsiloxanes, amino, alkyl alkylaryl and aryl silicone oils
- fats and oils including natural fats and oils such as jojoba, soyabean, rice bran, avocado, almond, olive, sesame, persic, castor, coconut, mink oils; cacao fat, beef tallow, lard; hardened oils obtained by hydrogenating the aforementioned oils; and synthetic mono, di and triglycerides such as myristic acid glyceride and 2-ethylhexanoic acid glyceride; c) waxes such as carnauba, spermaceti, beeswax, lanolin and derivatives thereof; d) hydrophobic plant extracts; e) hydrocarbons such as liquid paraffins, petroleum jelly, microcrystalline wax, ceresin, squalene, squalane, and mineral oil; f) higher fatty acids such
- sunscreens such as octyl methoxyl cinnamate
- the benefit agent may be incorporated in the compositions of the invention in a carrier.
- the carrier could itself be a benefit agent, such as an oil.
- Such benefit agents include lipids; alkyl lactates; sunscreens; esters such as isopropyl palmitate and isopropyl myristate; and vitamins.
- the carrier can, for example, be a silicone or hydrocarbon oil which is not solubilised/micellised by the surface active phase and in which the benefit agent is relatively soluble.
- Particularly preferred benefit agents include silicone oils, gums and modification thereof; esters such as isopropyl palmitate and myristate, and alkyl lactates.
- the benefit agent is preferably present in an amount of from
- composition 1.0 to 50 wt%, most preferably from 4 to 25 wt% of the composition, more preferably 5-15%, even more preferably 5- 10% by weight of the composition.
- composition according to the invention is that, during use, it deposits benefit agent onto the skin at a level which results in a perceivable benefit .
- the surface active agent can be selected from any known surfactant suitable for topical application to the human body. Mild surfactants, i.e. surfactants which do not damage the stratum corneum, the outer layer of skin, are particularly preferred. Because of their lathering properties, anionic surfactants are highly preferred components of compositions according to the invention. Where the composition contains an anionic surfactant, it is preferable that the composition also contains a co-surfactant, which can be a nonionic, cationic or zwitterionic surfactant.
- One preferred anionic detergent is fatty acyl isethionate of formula:
- R is an alkyl or alkenyl group of 7 to 21 carbon atoms and M is a solubilising cation such as sodium, potassium, ammonium or substituted ammonium.
- M is a solubilising cation such as sodium, potassium, ammonium or substituted ammonium.
- RCO groups Preferably at least three quarters of the RCO groups have 12 to 18 carbon atoms and may be derived from coconut, palm or a coconut/palm blend.
- alkyl ether sulphate of formula: RO(CH 2 CH 2 0)nS0 3 M where R is an alkyl group of 8 to 22 carbon atoms, n ranges from 0.5 to 10 especially from 1.5 to 8, and
- M is a solubilising cation as before.
- anionic detergents include alkyl glyceryl ether sulphate, sulphosuccinates, taurates, sarcosinates, sulphoacetates, alkyl phosphate, alkyl phosphate esters and acyl lactylate, alkyl glutamates and mixtures thereof.
- Sulphosuccinates may be monoalkyl sulphosuccinates having the formula: R O 2 CCH 2 CH (SO 3 M) CO 2 M; and amido-MEA sulphosuccinates of the formula: R 5 CONHCH 2 CH 2 ⁇ 2 CCH 2 CH(S0 3 M) C0 2 M; wherein R 5 ranges from Ce-C 20 alkyl, preferably C 12 -C 15 alkyl and M is a solubilising cation.
- Taurates are generally identified by the formula: R 5 C0NR CH 2 CH 2 S0 3 M, wherein R ranges from Cs-C 2 o alkyl, preferably C 12 -C 15 alkyl, R ranges from C 1 -C 4 alkyl, and M is a solubilising cation.
- Harsh surfactants such as primary alkane sulphonate or alkyl benzene sulphonate will generally be avoided.
- Suitable nonionic surface active agents include alkyl polysaccharides, lactobionamides, ethyleneglycol esters, glycerol monoethers, polyhydroxyamides (glucamide) , primary and secondary alcohol ethoxylates, especially the Cs- 20 aliphatic alcohols ethoxylated with an average of from 1 to 20 moles of ethylene oxide per mole of alcohol.
- the soap is preferably derived from materials with a C ⁇ to C 22 substantially saturated carbon chain and, preferably, is a potassium soap with a C 12 to Cis carbon chain.
- the surface active agent is preferably present at a level of from 1 to 35 wt%, preferably 3 to 30 wt% of the composition, more preferably at least 5% by weight of the composition.
- the composition includes from 0.5 to 15 wt% of a cosurfactant agent with skin-mildness benefits.
- Suitable materials are zwitterionic detergents which have an alkyl or alkenyl group of 7 to 18 carbon atoms and comply with an overall structural formula :-
- R 3 where R is alkyl or alkenyl of 7 to 18 carbon atoms
- R and R are each independently alkyl, hydroxyalkyl or carboxyalkyl of 1 to 3 carbon atoms; m is 2 to 4; n is 0 or 1;
- X is alkylene of 1 to 3 carbon atoms optionally substituted with hydroxyl
- Y is -CO 2 " or -SO 3 " .
- Zwitterionic detergents within the above general formula include simple betaines of formula:-
- R 1 , R2 and R3 are as defined previously.
- R may, in particular, be a mixture of C 12 and C 14 alkyl groups derived from coconut so that at least half, preferably at least three quarters, of the group R has 10
- R and R are preferably methyl .
- a further possibility is a sulphobetaine of formula:
- R , R and R in these formulae are as defined previously.
- a necessary component in compositions according to the invention is a cationic polymer.
- the cationic polymer may be a homopolymer or be formed from two or more types of monomers.
- the molecular weight of the polymer will generally be between 5 000 and 10 000 000, typically at least 10 000 and preferably in the range 100 000 to about 2 000 000.
- the polymers will have cationic nitrogen containing groups such as quaternary ammonium or protonated a ino groups , or a mixture thereof .
- the cationic nitrogen-containing group will generally be present as a substituent on a fraction of the total monomer units of the cationic polymer. Thus when the polymer is not a homopolymer it can contain spacer non-cationic monomer units.
- Such polymers are described in the CTFA Cosmetic Ingredient Directory, 7th edition.
- the ratio of the cationic to non- cationic monomer units is selected to give a polymer having a cationic charge density in the required range.
- Suitable cationic polymers include, for example, copolymers of vinyl monomers having cationic an ⁇ ine or quarternary ammonium functionalities with water soluble spacer monomers such as (meth) acrylamide, alkyl and dialkyl (meth) acrylamides, alkyl (meth) acrylate, vinyl caprolactone and vinyl pyrrolidine.
- the alkyl and dialkyl substituted monomers preferably have C1-C7 alkyl groups, more preferably Cl-3 alkyl groups.
- Other suitable spacers include vinyl esters, vinyl alcohol, maleic anyhdride, propylene glycol and ethylene glycol.
- the cationic amines can be primary, secondary or tertiary amines, depending upon the particular species and the pH of the composition. In general secondary and tertiary amines, especially tertiary, are preferred.
- Amine substituted vinyl monomers and amines can be polymerized in the amine form and then converted to ammonium by quarternization.
- the cationic polymers can comprise mixtures of monomer units derived from amine- and/or quaternary ammonium-substituted monomer and/or compatible spacer monomers.
- Suitable cationic polymers include, for example: copolymers of 1-vinyl-2-pyrrolidine and 1-vinyl-3- methyl-imidazolium salt (e.g. chloride salt), referred to in the industry by the Cosmetic, Toiletry, and Fragrance Association, (CTFA) as Polyquaternium-16.
- CTFA Cosmetic, Toiletry, and Fragrance Association
- This material is commercially available from BASF Wyandotte Corp. (Parsippany, NJ, USA) under the LUVIQUAT tradename (e.g. LUVIQUAT FC 370) ;
- cationic diallyl quaternary ammonium-containing polymers including, for example, dimethyldiallyammonium chloride homopolymer and copolymers of acrylamide and dimethyldiallylammonium chloride, referred to in the industry (CTFA) as Polyquaternium 6 and Polyquaternium 7, respectively;
- cationic polymers that can be used include cationic polysaccharide polymers, such as cationic cellulose derivatives, cationic starch derivatives, and cationic guar gum derivatives.
- Cationic polysaccharide polymers suitable for use in compositions of the invention include those of the formula:
- A is an anhydroglucose residual group, such as a starch or cellulose anhydroglucose residual
- R is an alkylene, oxyalkylene, polyoxyalkylene, or hydroxyalkylene
- R , R and R independently represent alkyl, aryl, alkylaryl, arylalkyl, alkoxyalkyl, or alkoxyaryl groups, each group containing up to about 18 carbon atoms.
- the total number of carbon atoms for each cationic moiety i.e., the sum of carbon atoms in
- R , R and R is preferably about 20 or less, and X is an anionic counterion.
- Cationic cellulose is available from Amerchol Corp. (Edison, NJ, USA) in their Polymer JR (trade mark) and LR (trade mark) series of polymers, as salts of hydroxyethyl cellulose reacted with trimethyl ammonium substituted epoxide, referred to in the industry (CTFA) as Polyquaternium 10.
- CTFA trimethyl ammonium substituted epoxide
- Another type of cationic cellulose includes the polymeric quaternary ammonium salts of hydroxyethyl cellulose reacted with lauryl dimethyl ammonium-substituted epoxide, referred to in the industry (CTFA) as Polyquaternium 24. These materials are available from Amerchol Corp. (Edison, NJ, USA) under the tradename Polymer LM-200.
- Suitable cationic polysaccharide polymers include quaternary nitrogen-containing cellulose ethers (e.g. as described in U.S. Patent 3,962,418), and copolymers of etherified cellulose and starch (e.g. as described in U.S. Patent 3,958,581) .
- a particularly suitable type of cationic polysaccharide polymer that can be used is a cationic guar gum derivative, such as guar hydroxypropyltrimonium chloride. (Commercially available from Rhone-Poulenc in their JAGUAR trademark series) .
- Examples are JAGUAR C13S, which has a low degree of substitution of the cationic groups and high viscosity, JAGUAR C15, having a moderate degree of substitution and a low viscosity, JAGUAR C17 (high degree of substitution, high viscosity), JAGUAR C16, which is a hyroxypropylated cationic guar derivative containing a low level of substituent groups as well as cationic quaternary ammonium groups, and JAGUAR 162 which is a high transparency, medium viscosity guar having a low degree of substitution.
- the cationic polymer is selected from cationic cellulose and cationic guar derivatives.
- Particularly preferred cationic polymers are JAGUAR C13S, JAGUAR C15, JAGUAR C17 and JAGUAR C16 and JAGUAR C162, especially Jaguar C13S, and cationic starches such as Softgel BDA (ex. Avebe) .
- Cationic polymer is present in composition at levels of 0.05- 3.0%, more preferably 0.4-3.0%, even more preferably 0.5-1.5% by weight of the composition.
- an auxiliary structurant may be added to the composition.
- suitable materials include swelling clays, for example laponite; cross-linked polyacrylates such as Carbopol (TM) (polymers available from Goodrich) ; acrylates and copolymers thereof; polyvinylpyrrolidone and copolymers thereof; polyethylene imines; polymeric carboxylates, consisting of and including modified and unmodified starches, unsubstituted quar gums, agars, alginates, xanthan gum, carrageenan, cellulose derivatives, exudate gum, gellan gum, gelatin, pectins and seed gums; gellants; and mixtures thereof.
- Suitable electrolytes include alkali and alkaline earth salts such as halides, ammonium salts and sulphates.
- the composition may also comprise a viscosity modifying agent, ie a material which adjusts the viscosity of the composition to be that which is suitable for and preferred by consumers.
- a viscosity modifying agent ie a material which adjusts the viscosity of the composition to be that which is suitable for and preferred by consumers.
- Suitable materials include ethylene glycols, propylene glycols, salts such as sodium chloride and ammonium sulphate; and sucrose esters.
- Preferred viscosity modifiers include PEG 18 glyceryl glycerol dioleococoate (Antil 171, ex. Goldschmidt) , PEG 55 propylene glycol oleate (Antil 141, ex. Goldschmidt), PEG 150 distearate and PEG 150 pentaerythrityl tetrastearate (Crothix, ex Croda) .
- Thickeners may also be added to the benefit agent in order to achieve the required viscosity during use.
- Preferred thickeners for the composition include fumed silica; polyethylene; alkyl silicone waxes; aluminium silicate; lanesterol; natural and synthetic waxes; fatty acids and derivatives thereof, in particular, fatty acid monoglyceride polyglycol ethers; higher fatty alcohols; petrolatum; narogel; polyammonium stearate; hydrotalcites; and mixtures thereof.
- Hydrotalcites are materials of general formula n+ x ⁇ [M m N n (OH) 2 (m + n) 1 X n/ X yH 0
- M is a divalent metal ion e.g. Mg ; N is a trivalent metal ion e.g. Al
- X is an exchangeable anion e.g CO 3 , NO 3 ; stearate, cinnimate.; m is the number of divalent metal ions; and n is the number of trivalent metal ions.
- composition comprises two or more benefit agents one of the benefit agents may also function as a thickening agent.
- the benefit agent may also function as a carrier to deliver efficacy agents to skin treated with the compositions of the invention.
- This route is particularly useful for delivering efficacy agents which are difficult to deposit onto the skin or those which suffer detrimental interactions with other components in the composition.
- the carrier is often a silicone or hydrocarbon oil which is not solubilised/micellised by the surface active phase and in which the efficacy agent is relatively soluble.
- efficacy agents include antiviral agents; hydroxycaprylic acids; pyrrolidone; carboxylic acids; 3 , 4, 4 ' -trichlorocarbanilide; benzoyl peroxide; perfumes; essential oils; germicides and insect repellants such as 2,4,4 ' -trichloro-2 ' -hydroxydiphenyl ether (Irgasan DP300) ; salicylic acid; willow extract, N,N-dimethyl m- toluamide (DEET) ; and mixtures thereof.
- antiviral agents include antiviral agents; hydroxycaprylic acids; pyrrolidone; carboxylic acids; 3 , 4, 4 ' -trichlorocarbanilide; benzoyl peroxide; perfumes; essential oils; germicides and insect repellants such as 2,4,4 ' -trichloro-2 ' -hydroxydiphenyl ether (Irgasan DP300) ; salicylic acid; willow extract
- compositions of the invention may be formulated as products for washing the skin, for example, bath or shower gels, hand washing compositions or facial washing liquids; pre- and post-shaving products; rinse-off, wipe-off and leave-on skin care products; products for washing the hair and for dental use.
- shower gels are particularly preferred product forms.
- compositions of the invention will generally be pourable liquids or semi-liquids e.g. pastes and will have a viscosity in the range 250 to 100,000 mPas measured at a shear rate of 10s and 25°C in a Haake Rotoviscometer RV20.
- the viscosity will generally be in the range 800 to 15000 mPas measured at a shear rate of 10s and 25°C.
- the viscosity will generally be in the range 3000 to 100,000 mPas measured at a shear rate of 10s and 25°C.
- Other typical components of such compositions include opacifiers, preferably 0.2 to 2.0 wt%; preservatives, preferably 0.2 to 2.0 wt% and perfumes, preferably 0.5 to 2.0 wt%.
- compositions according to the invention are also preferably deaerated or contain minimal incorporated air, in order to maximise product stability.
- compositions were prepared in line with the general method outlined above:
- compositions had the following viscosities (as measured with a Haake VT500) :
- compositions according to Examples 1 to 6 were assessed for their deposition of silicone oil onto a 12cm by 5 cm patch of porcine skin. Accordingly, porcine full thickness skin was prehydrated, and then 0.5ml of each composition was applied to it. The skin was lathered for 30 seconds, and then rinsed with three 200ml portions of 30°C water. Thereafter, the skin was wiped with a paper towel to remove excess water. Two minutes after drying, a strip of adhesive tape was pressed onto the skin for 30 seconds by applying a
- the adhesive tape employed was J-Lar Superclear tape having a width of 2.5cm. Strips of tape were taken from 3 adjacent sites on the skin.
- silicone which had deposited on the skin was subsequently transferred to the tape along with some of the outer layer of the skin.
- the amounts of silicon and skin adhering to the tape were determined by means of X-ray fluorescence spectroscopy.
- the tape strips were placed in an X-ray fluorescence spectrometer with the adhesive side facing the beam of the machine.
- a mask was applied over the tape to define a standardised area in the middle of the tape which was exposed to the X-ray beam.
- the sample chamber of the machine was placed under vacuum before making measurements and the spectrometer was then used to measure the quantities of silicon and sulphur. The sulphur was representative of the amount of skin which has transferred to the tape .
- the aggregation of silicone particles was observed and quantified using a Malvern Mastersizer.
- the apparatus was configured to detect silicone oil.
- the level employed enabled detection of silicone droplets and aggregates in the range 0.1-200 ⁇ m; the amount of shower gel composition used was selected to provide an absorbance value in the apparatus of 0.2-0.25.
- a small amount of shower gel was diluted under agitation in the sample presentation unit of the apparatus. Agitation was necessary to ensure that the shower gel dilution had occurred efficiently.
- compositions according to the invention where the relatively large particles comprising agglomerated individual silicone droplets have been deposited on the substrate.
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Detergent Compositions (AREA)
Abstract
Description
Claims
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR9916232-6A BR9916232A (en) | 1998-12-15 | 1999-12-03 | Aqueous liquid cleaning and wetting composition, and method for producing a composition |
HU0104764A HU228032B1 (en) | 1998-12-15 | 1999-12-03 | Aqueous liquid cleansing and moisturising composition and process for producing thereof |
AU15597/00A AU747078B2 (en) | 1998-12-15 | 1999-12-03 | Detergent composition |
AT99958172T ATE223198T1 (en) | 1998-12-15 | 1999-12-03 | DETERGENT COMPOSITION |
JP2000587737A JP4531262B2 (en) | 1998-12-15 | 1999-12-03 | Cleaning composition |
EP99958172A EP1140007B1 (en) | 1998-12-15 | 1999-12-03 | Detergent composition |
PL350090A PL197485B1 (en) | 1998-12-15 | 1999-12-03 | Detergent composition |
CA002354772A CA2354772C (en) | 1998-12-15 | 1999-12-03 | Aqueous cleansing and moisturising composition comprising aggregated particles |
DE69902815T DE69902815T2 (en) | 1998-12-15 | 1999-12-03 | DETERGENT COMPOSITION |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9827614.0 | 1998-12-15 | ||
GBGB9827614.0A GB9827614D0 (en) | 1998-12-15 | 1998-12-15 | Detergent composition |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2000035416A1 true WO2000035416A1 (en) | 2000-06-22 |
Family
ID=10844269
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1999/009588 WO2000035416A1 (en) | 1998-12-15 | 1999-12-03 | Detergent composition |
Country Status (19)
Country | Link |
---|---|
US (1) | US6255264B1 (en) |
EP (1) | EP1140007B1 (en) |
JP (1) | JP4531262B2 (en) |
KR (1) | KR100576658B1 (en) |
CN (1) | CN1273108C (en) |
AT (1) | ATE223198T1 (en) |
AU (1) | AU747078B2 (en) |
BR (1) | BR9916232A (en) |
CA (1) | CA2354772C (en) |
CZ (1) | CZ302598B6 (en) |
DE (1) | DE69902815T2 (en) |
ES (1) | ES2183629T3 (en) |
GB (1) | GB9827614D0 (en) |
HU (1) | HU228032B1 (en) |
ID (1) | ID30045A (en) |
PL (1) | PL197485B1 (en) |
RU (1) | RU2230548C2 (en) |
WO (1) | WO2000035416A1 (en) |
ZA (1) | ZA200104665B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002036095A2 (en) * | 2000-10-31 | 2002-05-10 | Unilever Plc | Personal cleansing composition |
WO2006076065A2 (en) * | 2005-01-10 | 2006-07-20 | Dow Global Technologies Inc. | Personal care compositions |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0126280D0 (en) * | 2001-11-01 | 2002-01-02 | Unilever Plc | Liquid detergent compositions |
US7037513B1 (en) | 2005-01-31 | 2006-05-02 | Aquea Scientific Corporation | Bodywash additives |
US6998113B1 (en) * | 2005-01-31 | 2006-02-14 | Aquea Scientific Corporation | Bodywashes containing additives |
US20060173709A1 (en) * | 2005-01-31 | 2006-08-03 | Traynor Daniel H | Bodywash additive business methods |
US7025952B1 (en) | 2005-01-31 | 2006-04-11 | Aquea Scientific Corporation | Methods of preparation and use of bodywashes containing additives |
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Also Published As
Publication number | Publication date |
---|---|
CZ20012194A3 (en) | 2001-11-14 |
CZ302598B6 (en) | 2011-07-27 |
PL350090A1 (en) | 2002-11-04 |
CN1334722A (en) | 2002-02-06 |
BR9916232A (en) | 2001-09-04 |
HUP0104764A2 (en) | 2002-05-29 |
HU228032B1 (en) | 2012-08-28 |
KR100576658B1 (en) | 2006-05-08 |
DE69902815T2 (en) | 2003-01-09 |
EP1140007B1 (en) | 2002-09-04 |
ES2183629T3 (en) | 2003-03-16 |
US6255264B1 (en) | 2001-07-03 |
AU747078B2 (en) | 2002-05-09 |
KR20010089570A (en) | 2001-10-06 |
AU1559700A (en) | 2000-07-03 |
ID30045A (en) | 2001-11-01 |
HUP0104764A3 (en) | 2011-04-28 |
JP4531262B2 (en) | 2010-08-25 |
CA2354772C (en) | 2009-02-10 |
JP2002532404A (en) | 2002-10-02 |
EP1140007A1 (en) | 2001-10-10 |
CN1273108C (en) | 2006-09-06 |
ZA200104665B (en) | 2002-06-07 |
GB9827614D0 (en) | 1999-02-10 |
RU2230548C2 (en) | 2004-06-20 |
ATE223198T1 (en) | 2002-09-15 |
PL197485B1 (en) | 2008-04-30 |
DE69902815D1 (en) | 2002-10-10 |
CA2354772A1 (en) | 2000-06-22 |
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