WO2000025596A1 - An apparatus in an infusor for a liquid food product - Google Patents

An apparatus in an infusor for a liquid food product Download PDF

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Publication number
WO2000025596A1
WO2000025596A1 PCT/SE1999/001987 SE9901987W WO0025596A1 WO 2000025596 A1 WO2000025596 A1 WO 2000025596A1 SE 9901987 W SE9901987 W SE 9901987W WO 0025596 A1 WO0025596 A1 WO 0025596A1
Authority
WO
WIPO (PCT)
Prior art keywords
product
autoclave
infusor
conical bottom
inlet
Prior art date
Application number
PCT/SE1999/001987
Other languages
French (fr)
Inventor
Bengt Palm
Original Assignee
Tetra Laval Holding & Finance Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tetra Laval Holding & Finance Sa filed Critical Tetra Laval Holding & Finance Sa
Priority to EP99971268A priority Critical patent/EP1124431B1/en
Priority to AU14344/00A priority patent/AU1434400A/en
Priority to BRPI9915012-3A priority patent/BR9915012B1/en
Priority to US09/831,021 priority patent/US6401603B1/en
Priority to DK99971268T priority patent/DK1124431T3/en
Priority to EA200100500A priority patent/EA002463B1/en
Priority to DE69916304T priority patent/DE69916304T2/en
Priority to AT99971268T priority patent/ATE263493T1/en
Priority to JP2000579062A priority patent/JP4201988B2/en
Priority to CA002349187A priority patent/CA2349187C/en
Publication of WO2000025596A1 publication Critical patent/WO2000025596A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C3/00Preservation of milk or milk preparations
    • A23C3/02Preservation of milk or milk preparations by heating
    • A23C3/03Preservation of milk or milk preparations by heating the materials being loose unpacked
    • A23C3/033Preservation of milk or milk preparations by heating the materials being loose unpacked and progressively transported through the apparatus
    • A23C3/037Preservation of milk or milk preparations by heating the materials being loose unpacked and progressively transported through the apparatus in direct contact with the heating medium, e.g. steam
    • A23C3/0375Preservation of milk or milk preparations by heating the materials being loose unpacked and progressively transported through the apparatus in direct contact with the heating medium, e.g. steam by pulverisation of the milk, including free falling film
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/16Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by heating loose unpacked materials
    • A23L3/18Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by heating loose unpacked materials while they are progressively transported through the apparatus
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/16Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by heating loose unpacked materials
    • A23L3/18Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by heating loose unpacked materials while they are progressively transported through the apparatus
    • A23L3/22Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by heating loose unpacked materials while they are progressively transported through the apparatus with transport through tubes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/16Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by heating loose unpacked materials
    • A23L3/24Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by heating loose unpacked materials with the materials in spray form

Abstract

The invention relates to an apparatus in an infusor (1) for a liquid food product. The infusor (1) is of the type which includes an autoclave (2) with a conical bottom (3). The autoclave (2) has an inlet (4) for the product located in its upper region, with a device for dividing the product into small droplets (6). The infuror also has an outlet (10) for the product located in the lower region of the autoclave (2), as well as an inlet (11) for steam. The conical bottom (3) of the autoclave (2) is filled to the greater part by a conically shaped body (15). The remaining space (16) in the bottom (3) of the autoclave (2) consists of a buffer cell. The stay volume of the product, which consists of that product which stays in the space (16) up to a liquid level (19, 20) may be varied steplessly.

Description

AN APPARATUS IN AN INFUSOR FOR A LIQUID FOOD PRODUCT
TECHNICAL FIELD
The present invention relates to an apparatus in an infusor for a liquid food product, of the type which includes an autoclave with a conical bottom, the autoclave having an inlet for the product located in its upper region, the inlet being disposed to divide the incoming product into the autoclave into small droplets, the infusor further including an outlet for the product located in the lower region of the autoclave, as well as an inlet for steam.
BACKGROUND ART
Heat treating food products for increased shelf life is a well-known and often employed method. The food products may, for example, be various dairy products such as milk, cream or yoghurt. The heat treatment may be put into effect in a plurality of different ways, directly or indirectly. Indirect methods are, for instance, heating using various types of heat exchangers. There are two main groups of direct methods, injection or infusion with steam. By employing a direct method, an extremely rapid heating will be obtained, which is to be sought for today since, in order to improve the flavour qualities, for instance in milk, it is many times the intention to heat the product to elevated temperatures for a brief interval of time.
The present invention relates to an apparatus in which use is made of infusion heating. Infusion entails that a finely divided liquid is heated in a steam chamber. The principle of heating a liquid, for example a liquid food, by injecting the liquid into a chamber filled with steam is known from the later part of the nineteenth century.
In principle, the infusor consists of an autoclave with a conical bottom. In the upper region of the autoclave there is an inlet for the product which is to be heat treated and there is also a device for dividing the product into small droplets which then fall through the autoclave. At the bottom of the autoclave, the droplets gather and form a liquid accumulation and finally depart from the autoclave through an outlet in its lower region. The autoclave also has an inlet for steam which may be placed in its upper region or alternatively its lower region. Regardless of the siting of the steam inlet, the purpose of the hot steam is to heat up the product droplets on their way down through the autoclave.
All modern heat treatment of food products has for its purpose, on the one hand to heat the product to a certain predetermined temperature, and on the other hand to keep the product at this temperature for a given predetermined interval of time. In connection with the heating of the product in an infusor, use is normally made of a separate buffer cell or pipe, i.e. a pipe length in direct connection with the product outlet of the autoclave. When the product leaves the autoclave, it is at a temperature close to boiling point and the displacement proper entails a pressure drop which consequently causes the product to boil. This boiling may give rise to frothing which entails a volume reduction and reduced control over how the product may be kept at a given temperature for a given interval of time. In order to prevent the product from boiling before reaching the buffer cell or pipe, the requirements of the authorities in several countries have required that a so-called lobe rotor pump be placed between the autoclave and the buffer cell, with a view to imparting a pressure increase to the product and thereby preventing boiling. A relatively expensive pump such as a lobe rotor pump is necessary, since the product is at a temperature of approximately 140-150°C
The liquid accumulation of heated product which gathers in the conical bottom region of the autoclave causes great uncertainty in the calculation of the stay time of the product, since the relatively large volume involved makes it impossible to know how long the product stays here, and that all parts of the product have been treated for the same interval of time.
OBJECTS OF THE INVENTION
One object of the present invention is to realise a buffer cell in the infusor which gives a reliable and controlled stay time for the product. In that the buffer cell constitutes a part of the infusor, the need for an additional buffer cell is eliminated, as well as the need for any possible pump placed between the infusor and the buffer cell.
A further object of the present invention is to realise a buffer cell which may be simply regulated for different time intervals in respect of the stay time, in that the volume in the buffer cell may be varied. SOLUTION
These and other objects have been attained according to the present invention in that the apparatus of the type described by way of introduction has been given the characterizing features that the conical bottom of the autoclave is, for the greater part, filled by a conically shaped body and that the remaining space in the bottom of the autoclave constitutes a buffer cell.
Preferred embodiments of the present invention have further been given the characterizing features as set forth in the appended subclaims.
BRIEF DESCRIPTION OF THE ACCOMPANYING DRAWINGS
One preferred embodiment of the apparatus according to the present invention will now be described in greater detail hereinbelow, with particular reference to the accompanying Drawings. In the accompanying Drawings: Fig. 1 is a side elevation, partly in section, of a state-of-the-art infusor;
Fig. 2 is a side elevation, partly in section, of an infusor according to the present invention;
Fig. 3 is a side elevation, partly in section, of a first embodiment of the lower region of the infusor; Fig. 4 is a side elevation, partly in section, of a second embodiment of the lower region of the infusor; and
Fig. 5 is a flow diagram for a plant for heat treatment by means of infusion heat.
The accompanying Drawings show only those parts and details essential to an understanding of the present invention.
DESCRIPTION OF PREFERRED EMBODIMENT
Fig. 1 shows a state-of-the-art infusor 1. The infusor 1 includes an autoclave 2 with a conical bottom 3. In the upper region of the autoclave 2, there is disposed an inlet 4 for the product which is to be heat treated. The product may consist of any liquid dairy product such as milk, cream or yoghurt. In association with the product inlet 4, there is a device 5 for dividing the incoming product into small droplets 6. The device for finely dividing the product may, for example, consist of a distributor chamber 7 which, in its lower wall 8, has a large number of apertures or gaps. The small product droplets 6 fall freely through the autoclave 2 and are re-accumulated in the conical bottom region 3 of the autoclave 2. Where the product re-accumulates, there is formed a relatively large liquid volume 9 before the product leaves the autoclave 2 through the outlet 10. Thereafter, the product is passed further to some form of buffer cell or pipe (not shown). In conventional infusors 1, an attempt is made to keep the liquid accumulation at a relatively constant level. The liquid accumulation may not become too small, since this may entail that heated product spatters on the inner walls of the autoclave 2, which may give rise to product burning on the walls.
The infusor 1 further includes an inlet 11 for steam. In Fig. 1, the steam inlet is placed in the lower region of the autoclave 2 and is disposed such that the steam spreads in the autoclave 2 through a concentric distributor chamber 12 and a concentric inlet gap 13. Alternatively, the steam inlet 11 may be placed in the upper region of the autoclave 2, in association with the product inlet 4.
The hot steam spreads within the autoclave 2 and the falling product droplets 6 meet the steam and are rapidly heated to the desired temperature. The heat treatment further includes the feature that the product is to be kept at this temperature for a given interval of time. Since it has not been possible to calculate the stay time in the large liquid volume 9, the stay time has instead been realised in that the product has passed a buffer pipe or buffer cell (not shown) placed after the infusor 1.
A conventional infusor 1 also includes some form of outlet 14 for the incondensable gases which are released in connection with the heating of the product. The infusor 1 is also provided with a number of pressure and temperature gauges for controlling the heat treatment process.
In order to avoid the large, uncontrollable liquid accumulation 9 which always occurs in conventional infusors 1, the infusor 1 according to the present invention (Fig. 2) has been provided with a conically shaped body 15. The body 15 should be as smooth as possible and is suitably an empty cavity in order to minimise weight. The body or cone 15 is designed such that it fills out the greater part of the space which constitutes the conical bottom 3 of the autoclave 2. The remaining space 16 in the bottom region 3 of the autoclave 2 constitutes a buffer cell. By avoiding the large "dead volume" which the liquid accumulation 9 entails in a conventional infusor, it is possible, as a result of the integrated buffer cell according to the present invention, to attain extremely short stay times for the product. Today, the intention is often - in order to improve the flavour of the product - that the product be treated at high temperature, approximately 150°C, during a very brief interval of time, of the order of 1-1.5 seconds.
At the upper edge of the cone 15, there are at least three guide stub shafts 17 distributed about its periphery. The guide stub shafts 17 reach the wall of the autoclave 2 and prevent the cone 15 from tilting.
The cone angle α of the body 15 may be the same as the cone angle β of the bottom 3, as is shown in Fig. 2. Alternatively, the cone angle α of the body 15 may be greater than the cone angle β of the bottom 3 of the autoclave 2, as shown in Figs. 3 and 4.
The volume which is accumulated in the space 16 may be mathematically calculated and, by dimensioning the cone angle α of the body 15 so that the desired flow will be obtained through the space 16, it is possible to compute an exact stay time for the product which passes through the space 16. By dimensioning the cone angle α of the body 15 so that it is larger than the cone angle β of the bottom region 3, it is possible to obtain a constant liquid flow rate through the space 16. The volume of the buffer cell is also to be calculated, and a certain slight volume must always exist above the cone 15. This is in order that the hot product does not burn fast, when the product droplets 6 reach the upper side 18 of the cone 15. Thus, the product will have a minimum liquid level 19, approximately 5-10 mm above the upper side 18 of the cone 15. A maximum liquid level 20 is also included.
By designing the upper side 18 of the cone 15 with a slight edge 21 approximately 5-10 mm above the upper side 18 of the cone 15, there will always be a liquid surface of 5-10 mm above the upper side 18 of the cone 15. Moreover, in Figs. 3 and 4, the upper side 18 of the cone 15 has been angled gently from its centre and out towards the edge 21 in order to obtain a better flow of the product.
The stay time, i.e. the time interval during which the product is kept at a certain temperature, depends upon what stay volume is in the infusor. The stay volume may be varied in two ways or by a combination of the two alternatives. This is on the one hand by governing the liquid level which is controlled by measuring a differential pressure. The differential pressure measurement takes place in measurement equipment 22 which receives its measurement values from two pressure gauges 23 and 24. The one pressure gauge 23 is placed just above the maximum liquid level 20 and the other pressure gauge 24 is placed in the product outlet 10. By calculating a norm value for the differential pressure for each stay time, it is thus possible to steplessly regulate the stay time. A larger difference gives an increased volume. The volume is regulated between a minimum time interval when the liquid surface of the product is located at the minimum level 19, and a maximum time interval when the liquid surface of the product is located at the maximum level 20. The liquid level is governed by means of an outlet valve 30 placed in the product outlet 10.
Alternatively, the stay volume may be varied in that the liquid level 19, 20 is kept constant, but that the cone 15 is raised or lowered in the bottom region 3. This regulation may, for example, take place as shown in Fig. 3 by means of a switching device 25 which, via a spindle 26, raises or lowers the entire cone 15. The guide stub shafts 17 constantly ensure that the cone 15 keeps in the correct position and that it does not tilt sideways. By employing different cone angles b for the bottom portion 3 as shown in Figs. 3 and 4, it is possible to some degree to modify the volume that constitutes the buffer cell.
By combining the two alternatives and allowing the liquid level 19, 20 to vary controlled by the differential pressure, at the same time as the body or cone 15 is raised or lowered by means of the switching device 25, it is possible to achieve a greater scope of regulation than afforded by both of the alternatives separately.
As is shown in Fig. 2, the conical bottom region 3 of the autoclave 2 may be made with a double wall 27. By supplying a coolant in an inlet 28 which may be evacuated through the outlet 29, deposition of coagulated product can be minimised without any appreciable cooling effect on the outflow temperature of the flow leaving the buffer cell.
Once the product has been ready heat-treated, i.e. it is heated to a certain predetermined temperature and has been kept at this temperature for a given predetermined time interval, the product must be cooled as rapidly as possible. A simple method of rapidly cooling the product is shown in Fig. 2. Having passed the outlet 10 and the outlet valve 30, the product enters into an expansion cooler 31. Given that the space occupied by the product rapidly expands, the pressure falls and the temperature will decrease. Thereafter the product is passed direct into a vacuum vessel 32.
Fig. 5 shows how an infusor 1 is included as a component in a complete plant for the heat treatment of a liquid food product by means of infusion heat. The incoming product 33 passes into the plant via a balance tank 34 and a pump 35. In a heat treatment unit 36, normally a plate heat exchanger, the product is pre-heated to the desired temperature, normally 75-82°C, but also temperatures of up to 120°C may occur. The thus preheated product is led in a conduit into the infusor 1 and is heated treated there in the above-described manner.
The ready-treated product is led from the infusor 1 to a vacuum vessel 32 where the addition of water which the product received as a result of the infusion heating is once again removed. Via a pump 37 and possibly a homogenizer 38, the product is led further to a cooler 39, for example a plate heat exchanger, where it is cooled to the desired temperature. The product then departs from the plant through a conduit 40 for further treatment or for final packing into consumer packages.
As will have been apparent from the foregoing description, the present invention realises an apparatus in an infusor which entails that a regulatable buffer cell is integrated in the infusor. The stay volume can be controlled and the uncontrollable liquid volume which is formed in the bottom of conventional infusors is avoided. As a result of the present invention, it is simpler to calculate exact stay times for the product and thereby reduce the thermal shock to which the product is subjected, which makes a favourable contribution to the flavour of the product.

Claims

WHAT IS CLAIMED IS:
1. An apparatus in an infusor (1) for a liquid food product, of the type which includes an autoclave (2) with a conical bottom (3), the autoclave (2) having an inlet (4) for the product located in its upper region, the inlet being disposed to divide the incoming product into the autoclave (2) into small droplets (6), the infusor (1) further including an outlet (10) for the product located in the lower region of the autoclave (2), as well as an inlet (11) for steam, characterized in that the conical bottom (3) of the autoclave (2) is filled for the greater part by a conically shaped body (15), and that the remaining space (16) in the bottom (3) of the autoclave (2) constitutes a buffer cell.
2. The apparatus as claimed in Claim 1, characterized in that the stay volume of the product consists of that product which stays in the space (16) up to a liquid level (19, 20) above the upper side (18) of the body (15).
3. The apparatus as claimed in Claim 2, characterized in that the stay volume may be varied in that the liquid level (19, 20) may vary between a minimum level (19) and a maximum level (20).
4. The apparatus as claimed in Claim 3, characterized in that the liquid level (19, 20) is regulated by means of an outlet valve (30) placed in the product outlet (10); and that the outlet valve (30) is controlled by a differential pressure between the pressure measured by a pressure gauge (24) placed in the product outlet (10) and the pressure measured by a pressure gauge (23) placed above the maximum level (20).
5. The apparatus as claimed in Claim 3, characterized in that the stay volume may be varied in that the conical body (15) may be moved upwards or downwards in the conical bottom (3) of the autoclave (2) by means of a switching device (25).
6. The apparatus as claimed in Claim 2, characterized in that the stay volume may be varied in that the liquid level (19, 20) may vary between a minimum level (19) and a maximum level (20) at the same time as the conical body (15) may be moved upwards or downwards in the conical bottom (3) of the autoclave (2) by means of a switching device (25).
7. The apparatus as claimed in any of Claims 2 to 6, characterized in that the upper side (18) of the body (15) is angled from the centre and out towards its periphery.
8. The apparatus as claimed in any of Claims 2 to 6, characterized in that the upper side (18) of the body (15) is provided with an edge (21) along its periphery.
9. The apparatus as claimed in any of the preceding Claims, characterized in that the body (15) is disposed to be kept in position in the conical bottom (3) by means of guide stub shafts (17).
10. The apparatus as claimed in any of the preceding Claims, characterized in that the body (15) has a cone angle which is greater than the cone angle β of the conical bottom (3).
PCT/SE1999/001987 1998-11-04 1999-11-03 An apparatus in an infusor for a liquid food product WO2000025596A1 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
EP99971268A EP1124431B1 (en) 1998-11-04 1999-11-03 An apparatus in an infusor for a liquid food product
AU14344/00A AU1434400A (en) 1998-11-04 1999-11-03 An apparatus in an infusor for a liquid food product
BRPI9915012-3A BR9915012B1 (en) 1998-11-04 1999-11-03 appliance in an infuser for a liquid food product.
US09/831,021 US6401603B1 (en) 1998-11-04 1999-11-03 Apparatus in an infusor for a liquid food product
DK99971268T DK1124431T3 (en) 1998-11-04 1999-11-03 Device in a liquid food infuser
EA200100500A EA002463B1 (en) 1998-11-04 1999-11-03 An apparatus in an infusor for a liquid food product
DE69916304T DE69916304T2 (en) 1998-11-04 1999-11-03 APPARATUS IN AN INFUSION SYSTEM FOR A LIQUID FOOD PRODUCT
AT99971268T ATE263493T1 (en) 1998-11-04 1999-11-03 APPARATUS IN AN INFUSION SYSTEM FOR A LIQUID FOOD PRODUCT
JP2000579062A JP4201988B2 (en) 1998-11-04 1999-11-03 Infuser equipment for liquid food
CA002349187A CA2349187C (en) 1998-11-04 1999-11-03 An apparatus in an infusor for a liquid food product

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9803766A SE513537C2 (en) 1998-11-04 1998-11-04 Device for an infuser for a liquid food product
SE9803766-6 1998-11-04

Publications (1)

Publication Number Publication Date
WO2000025596A1 true WO2000025596A1 (en) 2000-05-11

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PCT/SE1999/001987 WO2000025596A1 (en) 1998-11-04 1999-11-03 An apparatus in an infusor for a liquid food product

Country Status (14)

Country Link
US (1) US6401603B1 (en)
EP (1) EP1124431B1 (en)
JP (1) JP4201988B2 (en)
CN (1) CN1129362C (en)
AT (1) ATE263493T1 (en)
AU (1) AU1434400A (en)
BR (1) BR9915012B1 (en)
CA (1) CA2349187C (en)
DE (1) DE69916304T2 (en)
DK (1) DK1124431T3 (en)
EA (1) EA002463B1 (en)
ES (1) ES2220146T3 (en)
SE (1) SE513537C2 (en)
WO (1) WO2000025596A1 (en)

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WO1998046087A2 (en) * 1997-04-11 1998-10-22 Adriaan Gerrit Den Hollander A method and a device for heating a liquid

Cited By (3)

* Cited by examiner, † Cited by third party
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WO2010086082A1 (en) * 2009-01-27 2010-08-05 Gea Tds Gmbh Infusion system for a liquid food product and method for directly heating a liquid food product in an infusion system
DK178416B1 (en) * 2014-07-25 2016-02-15 Spx Flow Technology Danmark As Infusion plant
DK178429B1 (en) * 2014-07-25 2016-02-22 Spx Flow Technology Danmark As Infusion plant

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CA2349187A1 (en) 2000-05-11
AU1434400A (en) 2000-05-22
SE513537C2 (en) 2000-09-25
SE9803766L (en) 2000-05-05
BR9915012A (en) 2001-08-07
JP2002528102A (en) 2002-09-03
DE69916304T2 (en) 2005-05-04
SE9803766D0 (en) 1998-11-04
EA200100500A1 (en) 2001-10-22
CA2349187C (en) 2008-04-15
CN1129362C (en) 2003-12-03
EA002463B1 (en) 2002-04-25
ES2220146T3 (en) 2004-12-01
EP1124431A1 (en) 2001-08-22
DE69916304D1 (en) 2004-05-13
EP1124431B1 (en) 2004-04-07
ATE263493T1 (en) 2004-04-15
CN1325272A (en) 2001-12-05
US6401603B1 (en) 2002-06-11
JP4201988B2 (en) 2008-12-24
BR9915012B1 (en) 2009-12-01
DK1124431T3 (en) 2004-08-16

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