WO2000021437A3 - Infrared atr glucose measurement system - Google Patents

Infrared atr glucose measurement system

Info

Publication number
WO2000021437A3
WO2000021437A3 PCT/US1999/023823 US9923823W WO2000021437A3 WO 2000021437 A3 WO2000021437 A3 WO 2000021437A3 US 9923823 W US9923823 W US 9923823W WO 2000021437 A3 WO2000021437 A3 WO 2000021437A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
device
glucose
measurement
infrared
human
Prior art date
Application number
PCT/US1999/023823
Other languages
French (fr)
Other versions
WO2000021437A2 (en )
Inventor
Herbert L Berman
Jeffrey N Roe
Original Assignee
Herbert L Berman
Medoptix Inc
Jeffrey N Roe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Abstract

This involves a non-invasive glucose measurement device and a process for determining blood glucose level in the human body using the device. In typical operation, the glucose measurement device is self-normalizing in that it does not employ an independent reference sample in its operation. The device uses attenuated total reflection (ATR) infrared spectroscopy. Preferably, the device is used on a fingertip and compares two specific regions of a measured infrared spectrum to determine the blood glucose level of the user. Clearly, this device is especially suitable for monitoring glucose levels in the human body, and is especially beneficial to users having diabetes mellitus. The device and procedure may be used for other analyte materials which exhibit unique mid-IR signatures of the type described herein and that are found in appropriate regions of the outer skin.
PCT/US1999/023823 1998-10-13 1999-10-12 Infrared atr glucose measurement system WO2000021437A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US10388398 true 1998-10-13 1998-10-13
US60/103,883 1998-10-13

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
EP19990951963 EP1137364A2 (en) 1998-10-13 1999-10-12 Infrared atr glucose measurement system
JP2000575421A JP2002527136A (en) 1998-10-13 1999-10-12 Infrared atr glucose measurement system
CA 2347482 CA2347482C (en) 1998-10-13 1999-10-12 Infrared atr glucose measurement system
US09547433 US6424851B1 (en) 1998-10-13 2000-04-12 Infrared ATR glucose measurement system (II)
US09665391 US6362144B1 (en) 1998-10-13 2000-09-20 Cleaning system for infrared ATR glucose measurement system (II)
US09668848 US6424849B1 (en) 1998-10-13 2000-09-22 Self-contained method for determining blood glucose levels from an IR beam reflected from the surface of the skin
US09668222 US6445938B1 (en) 1998-10-13 2000-09-22 Method for determining blood glucose levels from a single surface of the skin
US09668207 US6421548B1 (en) 1998-10-13 2000-09-22 Infrared ATR glucose measurement system having an ATR with mirrored ends
US09668685 US6424848B1 (en) 1998-10-13 2000-09-22 Method for preparing skin surface and determining glucose levels from that surface
US09667987 US6430424B1 (en) 1998-10-13 2000-09-22 Infrared ATR glucose measurement system utilizing a single surface of skin
US10131562 US20020151773A1 (en) 1998-10-13 2002-04-23 Infrared ATR glucose measurement system (II)
US10358880 US20030176775A1 (en) 1998-10-13 2003-02-04 Cleaning kit for an infrared glucose measurement system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US09547433 Continuation-In-Part US6424851B1 (en) 1998-10-13 2000-04-12 Infrared ATR glucose measurement system (II)

Publications (2)

Publication Number Publication Date
WO2000021437A2 true WO2000021437A2 (en) 2000-04-20
WO2000021437A3 true true WO2000021437A3 (en) 2001-07-19

Family

ID=22297534

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/023823 WO2000021437A3 (en) 1998-10-13 1999-10-12 Infrared atr glucose measurement system

Country Status (5)

Country Link
EP (1) EP1137364A2 (en)
JP (1) JP2002527136A (en)
CN (1) CN1555242A (en)
CA (1) CA2347482C (en)
WO (1) WO2000021437A3 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6424851B1 (en) 1998-10-13 2002-07-23 Medoptix, Inc. Infrared ATR glucose measurement system (II)
WO2001037722A1 (en) * 1999-11-23 2001-05-31 Forskningscenter Risø A non-invasive method for the measurement of body fluid analytes
US6522903B1 (en) 2000-10-19 2003-02-18 Medoptix, Inc. Glucose measurement utilizing non-invasive assessment methods
JP3834224B2 (en) * 2001-06-28 2006-10-18 株式会社アドバンテスト Chemical detection method and apparatus
US20040132171A1 (en) * 2003-01-06 2004-07-08 Peter Rule Wearable device for measuring analyte concentration
WO2005027746A1 (en) * 2003-09-22 2005-03-31 Matsushita Electric Industrial Co., Ltd. Method of measuring glucose concentration and glucose concentration measuring apparatus
JP4777623B2 (en) * 2004-08-04 2011-09-21 日本電信電話株式会社 Biosensor and the measuring method
JP4607709B2 (en) 2005-08-26 2011-01-05 シャープ株式会社 Detecting device
WO2008062439A3 (en) * 2006-09-05 2008-08-14 Bansod Prashant Non-invasive blood glucose measurement using mid-infrared absorption spectroscopy
GB0708376D0 (en) 2007-05-01 2007-06-06 Alligator Bioscience Ab Novel polypeptides and uses thereof
US8390817B2 (en) * 2008-01-03 2013-03-05 Koninklijke Philips Electronics N.V. Evanescent field modulation in a biosensor
WO2011095072A1 (en) * 2010-02-04 2011-08-11 Isaac Wai Lam Kwok Devices and methods for non-invasive measurement of blood glucose by infrared dispersive reflection
CN103472023B (en) * 2012-06-06 2016-05-25 深圳职业技术学院 Engine oil detection system
CN105662434A (en) * 2016-04-12 2016-06-15 北京科宇佳科技有限公司 Mid-infrared noninvasive blood glucose detection equipment

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169676A (en) * 1976-02-20 1979-10-02 Nils Kaiser Method for determining the contents of metabolic products in the blood
US4427889A (en) * 1979-08-23 1984-01-24 Carl Zeiss Stiftung Method and apparatus for molecular spectroscopy, particularly for the determination of products of metabolism
US4538618A (en) * 1983-03-14 1985-09-03 Lior Rosenberg Fluid flow detector particularly useful for microvascular monitoring
US4710231A (en) * 1983-01-07 1987-12-01 Tate & Lyle Public Limited Company Solid fructose
EP0329361A2 (en) * 1988-02-13 1989-08-23 Suntory Limited 2-pyranone derivatives and process for production thereof
US5470323A (en) * 1992-12-07 1995-11-28 Creative Products Resource Associates, Ltd. Packaging system with in-tandem applicator pads for topical drug delivery
WO1996019180A1 (en) * 1994-12-20 1996-06-27 Maybelline Intermediate Co. Skin revitalizing makeup composition
WO1997029368A1 (en) * 1996-02-09 1997-08-14 Unisearch Limited Visual inspection system for leather hide

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169676A (en) * 1976-02-20 1979-10-02 Nils Kaiser Method for determining the contents of metabolic products in the blood
US4427889A (en) * 1979-08-23 1984-01-24 Carl Zeiss Stiftung Method and apparatus for molecular spectroscopy, particularly for the determination of products of metabolism
US4710231A (en) * 1983-01-07 1987-12-01 Tate & Lyle Public Limited Company Solid fructose
US4538618A (en) * 1983-03-14 1985-09-03 Lior Rosenberg Fluid flow detector particularly useful for microvascular monitoring
EP0329361A2 (en) * 1988-02-13 1989-08-23 Suntory Limited 2-pyranone derivatives and process for production thereof
US5470323A (en) * 1992-12-07 1995-11-28 Creative Products Resource Associates, Ltd. Packaging system with in-tandem applicator pads for topical drug delivery
WO1996019180A1 (en) * 1994-12-20 1996-06-27 Maybelline Intermediate Co. Skin revitalizing makeup composition
WO1997029368A1 (en) * 1996-02-09 1997-08-14 Unisearch Limited Visual inspection system for leather hide

Also Published As

Publication number Publication date Type
CA2347482C (en) 2005-02-08 grant
CN1555242A (en) 2004-12-15 application
EP1137364A2 (en) 2001-10-04 application
JP2002527136A (en) 2002-08-27 application
WO2000021437A2 (en) 2000-04-20 application
CA2347482A1 (en) 2000-04-20 application

Similar Documents

Publication Publication Date Title
US6675029B2 (en) Apparatus and method for quantification of tissue hydration using diffuse reflectance spectroscopy
US6671528B2 (en) Method and apparatus for non-invasive blood constituent monitoring
US7066885B2 (en) Interstitial fluid collection and constituent measurement
US5054487A (en) Laser systems for material analysis based on reflectance ratio detection
US5615672A (en) Self-emission noninvasive infrared spectrophotometer with body temperature compensation
US6534012B1 (en) Apparatus and method for reproducibly modifying localized absorption and scattering coefficients at a tissue measurement site during optical sampling
US6602205B1 (en) Interstitial fluid collection and constituent measurement
US5692503A (en) Method for noninvasive (in-vivo) total hemoglobin, oxyhemogolobin, deoxyhemoglobin, carboxyhemoglobin and methemoglobin concentration determination
US6236047B1 (en) Method for multi-spectral analysis of organic blood analytes in noninvasive infrared spectroscopy
Vashist Non-invasive glucose monitoring technology in diabetes management: A review
US6442408B1 (en) Method for quantification of stratum corneum hydration using diffuse reflectance spectroscopy
Burmeister et al. Noninvasive blood glucose measurements by near-infrared transmission spectroscopy across human tongues
US5362966A (en) Measurement of finger temperature in near-infrared quantitative measurement instrument
US6919566B1 (en) Method of calibrating a spectroscopic device
US6157442A (en) Micro optical fiber sensor device
US20030109777A1 (en) Consolidated body fluid testing device and method
US20050267346A1 (en) Non-invasive blood component measurement system
US5945676A (en) Method and apparatus for multi-spectral analysis in noninvasive NIR spectroscopy
US20040127777A1 (en) Indirect measurement of tissue analytes through tissue properties
US20060264717A1 (en) Photoacoustic assay method and apparatus
US7010336B2 (en) Measurement site dependent data preprocessing method for robust calibration and prediction
US5827181A (en) Noninvasive blood chemistry measurement method and system
US20030040683A1 (en) Site selection for determining analyte concentration in living tissue
US20060195023A1 (en) Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy
US20040015060A1 (en) Measurement of body compounds

Legal Events

Date Code Title Description
ENP Entry into the national phase in:

Ref country code: AU

Ref document number: 1999 64286

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 09547433

Country of ref document: US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

AK Designated states

Kind code of ref document: A2

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: PA/a/2001/003773

Country of ref document: MX

Ref document number: 142545

Country of ref document: IL

ENP Entry into the national phase in:

Ref country code: CA

Ref document number: 2347482

Kind code of ref document: A

Format of ref document f/p: F

Ref document number: 2347482

Country of ref document: CA

ENP Entry into the national phase in:

Ref country code: JP

Ref document number: 2000 575421

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 64286/99

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 1999951963

Country of ref document: EP

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

AK Designated states

Kind code of ref document: A3

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWP Wipo information: published in national office

Ref document number: 1999951963

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 64286/99

Country of ref document: AU

WWW Wipo information: withdrawn in national office

Ref document number: 1999951963

Country of ref document: EP