WO2000010461A1 - Image intensifier reticle system - Google Patents

Image intensifier reticle system Download PDF

Info

Publication number
WO2000010461A1
WO2000010461A1 PCT/US1999/012609 US9912609W WO0010461A1 WO 2000010461 A1 WO2000010461 A1 WO 2000010461A1 US 9912609 W US9912609 W US 9912609W WO 0010461 A1 WO0010461 A1 WO 0010461A1
Authority
WO
WIPO (PCT)
Prior art keywords
arm
plane
image intensifier
rotation
aligning
Prior art date
Application number
PCT/US1999/012609
Other languages
French (fr)
Other versions
WO2000010461A8 (en
Inventor
James F. Marino
Original Assignee
Nuvasive, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuvasive, Inc. filed Critical Nuvasive, Inc.
Priority to AU46744/99A priority Critical patent/AU4674499A/en
Priority to JP2000565788A priority patent/JP2002529117A/en
Priority to KR1020007013959A priority patent/KR20010071658A/en
Priority to EP99930147A priority patent/EP1093342A4/en
Priority to CA002334693A priority patent/CA2334693A1/en
Publication of WO2000010461A1 publication Critical patent/WO2000010461A1/en
Publication of WO2000010461A8 publication Critical patent/WO2000010461A8/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/54Control of apparatus or devices for radiation diagnosis
    • A61B6/547Control of apparatus or devices for radiation diagnosis involving tracking of position of the device or parts of the device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/08Auxiliary means for directing the radiation beam to a particular spot, e.g. using light beams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/12Devices for detecting or locating foreign bodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/44Constructional features of apparatus for radiation diagnosis
    • A61B6/4429Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units
    • A61B6/4435Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units the source unit and the detector unit being coupled by a rigid structure
    • A61B6/4441Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units the source unit and the detector unit being coupled by a rigid structure the rigid structure being a C-arm or U-arm

Definitions

  • the present invention relates to C-arm surgical image intensifiers.
  • the present invention provides a reticle for attachment to an image intensifier and a method of use which allows a standard C-arm image intensifier to be easily aligned to rotate in a selected plane about any desired point in a human body.
  • the present invention can be used to align an image intensifier to rotate in any plane through the human body, wherein the plane is preferably defined by viewing bones or other radio-opaque structures in the body with the image intensifier system.
  • the present invention can be aligned to rotate the C-arm in any desired plane passing through a human body, the present invention is ideally suited to align a conventional C-arm image intensifier to rotate in a plane passing between two adjacent vertebrae in a patient's spine.
  • the present invention is not so limited to alignment of C-arm image intensifiers only with respect to intervertebral planes .
  • the image intensifier can be rotated about a selected point to provide both lateral and anterior-posterior views through the patient while remaining in the selected intervertebral plane .
  • Fig. 1 is a rear elevation view of a prone lying patient with an image intensifier taking a lateral view through the patient .
  • Fig. 2 is a view corresponding to Fig. 1, but with the image intensifier taking an anterior-posterior view through the patient .
  • Fig. 3 is a side elevation view corresponding to Fig. 1.
  • Fig. 4 is a view of an image taken by the image intensifier with the image intensifier being positioned as shown in Figs . 1 and 3.
  • Fig. 5 is a sectional side elevation view taken along line 5-5 in Fig. 2.
  • Fig. 6 is a view of an image taken by the image intensifier with the image intensifier being positioned as shown in Figs . 2 and 5.
  • Fig. 7 is an end view of a reticle of the present invention as attached over the receiving end of the image intensifier.
  • a patient 10 having a spine 12, head 13 and feet 14 is positioned in a prone lying manner on a radiotransparent table 15.
  • a conventional image intensifier 20 having an emitter 22 and a receiver 24 which are together held on opposite sides of the patient by a standard C-arm 26 is positioned as shown in Fig. 1 to generate a lateral radioimage view through the patient .
  • C-arm 26 can also be rotated so as to provide an anterior-posterior image through the patient.
  • C-arm image intensifier 20 may comprise any standard image intensifier, preferably having the property that rotation 24 of C-arm 26 in the plane of the C-arm, (such as from the orientation in Fig. 1 to that of Fig. 2) , causes the image intensifier to rotate about a fixed point in space equidistant between emitter 22 and a receiver 24.
  • C- arm 26 is aligned to rotate in a preferred plane about a desired point in space positioned equidistant between emitter 22 and a receiver 24.
  • the desired point in space is disposed within the patient's intervertebral space and the desired plane is an intervertebral plane which passes between adjacent vertebrae, as follows.
  • each pair of adjacent vertebrae in the patient's spine will have a different intervertebral plane due to the natural lordosis in the patient's spine.
  • spine 12 comprises adjacent vertebrae 17 and 19.
  • Each pair of adjacent vertebrae in the spine will each have a unique intervertebral plane passing therethrough.
  • intervertebral plane 30 will pass between vertebrae 17 and 19, as shown. Accordingly, considerable adjustment of the image intensifier orientation is required to align it with the selected intervertebral plane.
  • the present invention may be used to align C-arm 26 image intensifier 20 with intervertebral plane 30 such that as the image intensifier is moved from the position shown in Fig. 1 to the position shown in Fig. 2, C-arm 26 of image intensifier 20 remains at all times disposed in the intervertebral plane 30, as follows .
  • the positioning of the image intensifier 20 to align C-arm 26 with a selected intervertebral plane 30 will require C-arm 26 to be rotated by angle Al to a vertical plane 32.
  • the point 34 about which image intensifier 20 is pivoted should preferably be between adjacent vertebrae 17 and 19, (as determined by viewing the lateral image through the patient as shown in Fig. 4 as will be explained) .
  • Image intensifier 20 is preferably initially positioned about the patient such that point 34 will be disposed equidistant between emitter 22 and a receiver 24. Accordingly, rotation of C-arm 26 in plane 30 will be about point 34 with point 34 remaining equidistant between emitter 22 and a receiver 24.
  • the correct angling of C-arm 26 about point 34 is accomplished as follows.
  • reticle 25 which has radiopaque indicia, for example, crosshairs 40 and 42 as shown in Fig. 7. Being radiopaque, crosshairs 40 and 42 will also appear on the image viewed by the system operator.
  • C-arm 26 of image intensifier 20 will enable the image of the intersection point of crosshairs 40 and 42 to be positioned between adjacent vertebrae 17 and 19 collinear with point 34 as shown when the C-arm is positioned to take an anterior-posterior view as illustrated in Figs. 2 and 6.
  • C-arm 26 can be rotated by oblique angle A2.
  • the image intensifier can then be rotated to any position in plane 30 about point 34, (which is also viewable as the intersection point of crosshairs 40 and 42) , including an anterior-posterior orientation as is shown in Figs. 3 and 5, thus aligning C-arm 26 of image intensifier 20 with the intervertebral plane 30.
  • image intensifier 20 can then be easily rotated into the position shown in Figs. 2 and 5 with C-arm 26 remaining in plane 30 to take an anterior-posterior image. It is to be understood that alignment of image intensifier 20 with plane 32 can also be accomplished first with the image intensifier positioned to take an anterior- posterior view.
  • Fig. 6 shows an illustration of the image intensifier view through adjacent vertebrae 17 and 19 taken along intervertebral plane 30 when the image intensifier is positioned in the orientation shown in Figs. 2 and 5. Subsequently, image intensifier 20 can be easily rotated to take a lateral view while C-arm 26 remains in the selected intervertebral plane 30. Alignment of the image intensifier with the selected intervertebral plane can also be accomplished at positions between lateral and anterior- posterior orientations.

Abstract

A method of aligning a C-arm (26) of an image intensifier for rotation in a selected plane, the C-arm having a transmitter (22) mounted at one end and a receiver (24) mounted at an opposite end, comprising: identifying the selected plane by viewing the location of bony structure (12) with the image intensifier; and aligning indicia disposed on a radio-opaque reticle (25) covering at least a portion of the receiver with the selected plane, the indicia being aligned with the plane of rotation of the C-arm, thereby aligning the plane of the C-arm with the selected plane.

Description

IMAGE INTENSIFIER RETICLE SYSTEM
CROSS-REFERENCES TO RELATED APPLICATIONS
The present application is a regular application claiming benefit under 35 USC §119 (e) from U.S. Provisional Patent Application Serial No. 60/120,663 filed February 19, 1999; the complete disclosure of which is hereby incorporated herein by reference in its entirety for all purposes .
TECHNICAL FIELD
The present invention relates to C-arm surgical image intensifiers.
SUMMARY OF THE INVENTION
The present invention provides a reticle for attachment to an image intensifier and a method of use which allows a standard C-arm image intensifier to be easily aligned to rotate in a selected plane about any desired point in a human body. The present invention can be used to align an image intensifier to rotate in any plane through the human body, wherein the plane is preferably defined by viewing bones or other radio-opaque structures in the body with the image intensifier system. Although the present invention can be aligned to rotate the C-arm in any desired plane passing through a human body, the present invention is ideally suited to align a conventional C-arm image intensifier to rotate in a plane passing between two adjacent vertebrae in a patient's spine. It is to be understood, however, that the present invention is not so limited to alignment of C-arm image intensifiers only with respect to intervertebral planes . After aligning the orientation of the image intensifier with the selected intervertebral plane, the image intensifier can be rotated about a selected point to provide both lateral and anterior-posterior views through the patient while remaining in the selected intervertebral plane .
BRIEF DESCRIPTION OF THE DRAWINGS
Fig. 1 is a rear elevation view of a prone lying patient with an image intensifier taking a lateral view through the patient .
Fig. 2 is a view corresponding to Fig. 1, but with the image intensifier taking an anterior-posterior view through the patient .
Fig. 3 is a side elevation view corresponding to Fig. 1.
Fig. 4 is a view of an image taken by the image intensifier with the image intensifier being positioned as shown in Figs . 1 and 3.
Fig. 5 is a sectional side elevation view taken along line 5-5 in Fig. 2.
Fig. 6 is a view of an image taken by the image intensifier with the image intensifier being positioned as shown in Figs . 2 and 5.
Fig. 7 is an end view of a reticle of the present invention as attached over the receiving end of the image intensifier.
DESCRIPTION OF THE SPECIFIC EMBODIMENTS
Referring first to Fig. 1, a patient 10 having a spine 12, head 13 and feet 14 is positioned in a prone lying manner on a radiotransparent table 15. A conventional image intensifier 20 having an emitter 22 and a receiver 24 which are together held on opposite sides of the patient by a standard C-arm 26 is positioned as shown in Fig. 1 to generate a lateral radioimage view through the patient . As is shown in Fig. 2, C-arm 26 can also be rotated so as to provide an anterior-posterior image through the patient. C-arm image intensifier 20 may comprise any standard image intensifier, preferably having the property that rotation 24 of C-arm 26 in the plane of the C-arm, (such as from the orientation in Fig. 1 to that of Fig. 2) , causes the image intensifier to rotate about a fixed point in space equidistant between emitter 22 and a receiver 24.
In a preferred aspect of the present invention, C- arm 26 is aligned to rotate in a preferred plane about a desired point in space positioned equidistant between emitter 22 and a receiver 24.
In an exemplary aspect of the invention, the desired point in space is disposed within the patient's intervertebral space and the desired plane is an intervertebral plane which passes between adjacent vertebrae, as follows.
When taking either lateral or an anterior- posterior images of adjacent vertebrae in the patient's spine, as seen in Figs. 1 and 2, respectively, it is preferred to take such images along a plane which passes between the adjacent vertebrae. However, each pair of adjacent vertebrae in the patient's spine will have a different intervertebral plane due to the natural lordosis in the patient's spine. For example, as is seen in Fig. 5, spine 12 comprises adjacent vertebrae 17 and 19. Each pair of adjacent vertebrae in the spine will each have a unique intervertebral plane passing therethrough. For example, intervertebral plane 30 will pass between vertebrae 17 and 19, as shown. Accordingly, considerable adjustment of the image intensifier orientation is required to align it with the selected intervertebral plane. These alignment problems are further complicated when attempting to rotate the image intensifier from a lateral position to an anterior-posterior position.
In a preferred aspect, the present invention may be used to align C-arm 26 image intensifier 20 with intervertebral plane 30 such that as the image intensifier is moved from the position shown in Fig. 1 to the position shown in Fig. 2, C-arm 26 of image intensifier 20 remains at all times disposed in the intervertebral plane 30, as follows .
As can be seen in Figs. 3 and 5, the positioning of the image intensifier 20 to align C-arm 26 with a selected intervertebral plane 30 will require C-arm 26 to be rotated by angle Al to a vertical plane 32. The point 34 about which image intensifier 20 is pivoted should preferably be between adjacent vertebrae 17 and 19, (as determined by viewing the lateral image through the patient as shown in Fig. 4 as will be explained) . Image intensifier 20 is preferably initially positioned about the patient such that point 34 will be disposed equidistant between emitter 22 and a receiver 24. Accordingly, rotation of C-arm 26 in plane 30 will be about point 34 with point 34 remaining equidistant between emitter 22 and a receiver 24. The correct angling of C-arm 26 about point 34 is accomplished as follows.
As is seen in Fig. 4, when the image intensifier is positioned as shown in Figs. 1 and 3, images of adjacent vertebrae 17 and 19 will be seen. Receiver 24 is covered with reticle 25 which has radiopaque indicia, for example, crosshairs 40 and 42 as shown in Fig. 7. Being radiopaque, crosshairs 40 and 42 will also appear on the image viewed by the system operator.
Adjusting the vertical and horizontal position of C-arm 26 of image intensifier 20 will enable the image of the intersection point of crosshairs 40 and 42 to be positioned between adjacent vertebrae 17 and 19 collinear with point 34 when the C-arm is positioned to take a lateral view as illustrated in Figs. 1 and 4.
Similarly, adjusting the vertical and horizontal position of C-arm 26 of image intensifier 20 will enable the image of the intersection point of crosshairs 40 and 42 to be positioned between adjacent vertebrae 17 and 19 collinear with point 34 as shown when the C-arm is positioned to take an anterior-posterior view as illustrated in Figs. 2 and 6. In order to align C-arm 26 in the anterior-posterior view of Figs. 2 and 6, C-arm 26 can be rotated by oblique angle A2.
When crosshairs 40 are aligned in the intervertebral plane in both lateral and anterior-posterior images, rotation of C-arm 26 in its plane of rotation (ie: the plane defined by crosshair 40 on reticle 25, about point 34), will align the C-arm for rotation in a plane which is co-planar to the patient's intervertebral plane. Specifically, when reticle 25 is initially attached to receiver 24, crosshairs 40 are pre-aligned to be coplanar with the plane of rotation of C-arm 26 as is shown in Fig. 7.
After aligning radiopaque crosshairs 40 with intervertebral plane 32, the image intensifier can then be rotated to any position in plane 30 about point 34, (which is also viewable as the intersection point of crosshairs 40 and 42) , including an anterior-posterior orientation as is shown in Figs. 3 and 5, thus aligning C-arm 26 of image intensifier 20 with the intervertebral plane 30. Once positioned as is shown in Figs. 1 and 3, image intensifier 20 can then be easily rotated into the position shown in Figs. 2 and 5 with C-arm 26 remaining in plane 30 to take an anterior-posterior image. It is to be understood that alignment of image intensifier 20 with plane 32 can also be accomplished first with the image intensifier positioned to take an anterior- posterior view. For example, Fig. 6 shows an illustration of the image intensifier view through adjacent vertebrae 17 and 19 taken along intervertebral plane 30 when the image intensifier is positioned in the orientation shown in Figs. 2 and 5. Subsequently, image intensifier 20 can be easily rotated to take a lateral view while C-arm 26 remains in the selected intervertebral plane 30. Alignment of the image intensifier with the selected intervertebral plane can also be accomplished at positions between lateral and anterior- posterior orientations.
While the above is a complete description of the preferred embodiments of the invention, various alternatives, modifications, and equivalents may be used. Therefore, the above description should not be taken as limiting the scope of the invention which is defined by the appended claims.

Claims

WHAT IS CLAIMED IS:
1. A method of aligning a C-arm of an image intensifier for rotation in a selected plane, the C-arm having a transmitter mounted at one end and a receiver mounted at an opposite end, comprising: identifying the selected plane by viewing the location of bony structures with the image intensifier; and aligning indicia disposed on a radio-opaque reticle covering at least a portion of the receiver with the selected plane, the indicia being aligned with the plane of rotation of the C-arm, thereby aligning the plane of the C- arm with the selected plane.
2. The method of claim 1, further comprising: rotating the C-arm in the selected plane.
3. The method of claim 1, further comprising: rotating the C-arm about a selected point in the selected plane .
4. The method of claim 3, wherein the C-arm is positioned such that the selected point is positioned equidistantly between the receiver and the emitter disposed at opposite ends of the C-arm.
5. The method of claim 3 , wherein the indicia comprise first indicia disposed in the plane of rotation of the C-arm and second indicia disposed perpendicular to the plane of rotation of the C-arm.
6. The method of claim 5, further comprising: centering the selected point between the first and second indicia.
7. The method of any of claims 1 to 6 , wherein, the selected plane is an intervertebral plane.
8. A reticle for aligning a C-arm of an image intensifier for rotation in a selected plane, the C-arm having a transmitter mounted at one end and a receiver mounted at an opposite end, comprising: first indicia disposed in the plane or rotation of the C-arm and second indicia disposed perpendicular to the plane of rotation of the C-arm.
9. A crosshair reticle for attachment to an image intensifier receiver for aligning the image intensifier with an intervertebral plane passing between adjacent vertebrae.
PCT/US1999/012609 1998-06-09 1999-06-04 Image intensifier reticle system WO2000010461A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU46744/99A AU4674499A (en) 1998-06-09 1999-06-04 Image intensifier reticle system
JP2000565788A JP2002529117A (en) 1998-06-09 1999-06-04 Image amplifier reticle system
KR1020007013959A KR20010071658A (en) 1998-06-09 1999-06-04 Image intensifier reticle system
EP99930147A EP1093342A4 (en) 1998-06-09 1999-06-04 Image intensifier reticle system
CA002334693A CA2334693A1 (en) 1998-06-09 1999-06-04 Image intensifier reticle system

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8866398P 1998-06-09 1998-06-09
US12066399P 1999-02-19 1999-02-19
US60/120,663 1999-02-19
US60/088,663 1999-06-04

Publications (2)

Publication Number Publication Date
WO2000010461A1 true WO2000010461A1 (en) 2000-03-02
WO2000010461A8 WO2000010461A8 (en) 2001-07-12

Family

ID=26778924

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/012609 WO2000010461A1 (en) 1998-06-09 1999-06-04 Image intensifier reticle system

Country Status (2)

Country Link
CA (1) CA2334693A1 (en)
WO (1) WO2000010461A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7600915B2 (en) 2004-12-01 2009-10-13 Trinity Orthopedics, Llc Imager based object positioner system and method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4722336A (en) * 1985-01-25 1988-02-02 Michael Kim Placement guide

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4722336A (en) * 1985-01-25 1988-02-02 Michael Kim Placement guide

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1093342A4 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7600915B2 (en) 2004-12-01 2009-10-13 Trinity Orthopedics, Llc Imager based object positioner system and method
US8007172B2 (en) 2004-12-01 2011-08-30 Trinity Orthopedics, Llc Imager based object positioner system and method

Also Published As

Publication number Publication date
WO2000010461A8 (en) 2001-07-12
CA2334693A1 (en) 2000-03-02

Similar Documents

Publication Publication Date Title
AU4674499A (en) Image intensifier reticle system
US6266394B1 (en) Image intensifier reticle system
US6519319B1 (en) Image intensifier reticle system
US5999837A (en) Localizing and orienting probe for view devices
US7637913B2 (en) Spinal midline indicator
US6267502B1 (en) Alignment verification device and method of using the same with a visual light beam and an x-ray
EP0905538B1 (en) Microscope calibration
US5387220A (en) Stereotactic frame and localization method
US20050113809A1 (en) Multiple cannula image guided tool for image guided procedures
US11534210B2 (en) Apparatus and method for minimally invasive osteosynthesis of sacroiliac luxations/fractures
JPH11244300A (en) Guide pin placing device and using method thereof
JP2005533579A (en) Multiple bone tracker
WO2003043485A3 (en) Computer assisted intramedullary rod surgery system
WO2003063682A3 (en) Extramedullary fluoroscopic alignment guide
WO2001030257A1 (en) Surgical sensor
CA2422950A1 (en) Fluoroscopic registration artifact with optical and/or magnetic markers
US20210022828A1 (en) Spinous process clamp
US8007172B2 (en) Imager based object positioner system and method
US11944326B2 (en) Systems and methods for transcorporeal microdecompression
US8568421B2 (en) Apparatus and method for aligning and positioning implants in a body
EP4225196A1 (en) Spinous process clamp
EP1742584B1 (en) Automatic pointing device for correct positioning of the distal locking screws of an intramedullary nail
US6829326B2 (en) Method for imaging the head area
US20140155796A1 (en) Back brace type surgery positioning apparatus and navigation system having the same
US20210045816A1 (en) Spinal orientation system

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 1999930147

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2334693

Country of ref document: CA

Ref country code: JP

Ref document number: 2000 565788

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 1020007013959

Country of ref document: KR

WWE Wipo information: entry into national phase

Ref document number: 46744/99

Country of ref document: AU

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWP Wipo information: published in national office

Ref document number: 1999930147

Country of ref document: EP

AK Designated states

Kind code of ref document: C1

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: C1

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

CFP Corrected version of a pamphlet front page
CR1 Correction of entry in section i

Free format text: PAT. BUL. 09/2000 UNDER (30) REPLACE "60/088863" BY "60/088663"

WWP Wipo information: published in national office

Ref document number: 1020007013959

Country of ref document: KR

WWW Wipo information: withdrawn in national office

Ref document number: 1999930147

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1020007013959

Country of ref document: KR