WO1999036530A3 - Lh-receptor gene promoter for tissue-specific gene expression - Google Patents

Lh-receptor gene promoter for tissue-specific gene expression Download PDF

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Publication number
WO1999036530A3
WO1999036530A3 PCT/EP1999/000361 EP9900361W WO9936530A3 WO 1999036530 A3 WO1999036530 A3 WO 1999036530A3 EP 9900361 W EP9900361 W EP 9900361W WO 9936530 A3 WO9936530 A3 WO 9936530A3
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
gene expression
receptor
gene promoter
promoter
Prior art date
Application number
PCT/EP1999/000361
Other languages
French (fr)
Other versions
WO1999036530A2 (en
Inventor
Olaf G Wilhelm
Manfred Schmitt
Sabine Wilhelm
Original Assignee
Wilex Biotechnology Gmbh
Olaf G Wilhelm
Manfred Schmitt
Sabine Wilhelm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wilex Biotechnology Gmbh, Olaf G Wilhelm, Manfred Schmitt, Sabine Wilhelm filed Critical Wilex Biotechnology Gmbh
Priority to AU28288/99A priority Critical patent/AU2828899A/en
Priority to CA002318660A priority patent/CA2318660A1/en
Priority to EP99908806A priority patent/EP1049779A2/en
Publication of WO1999036530A2 publication Critical patent/WO1999036530A2/en
Publication of WO1999036530A3 publication Critical patent/WO1999036530A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to a recombinant nucleic acid molecule comprising a LH-receptor gene promoter sequence capable of selectively directing gene expression in human ovarian-derived cells.
PCT/EP1999/000361 1998-01-20 1999-01-20 Lh-receptor gene promoter for tissue-specific gene expression WO1999036530A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU28288/99A AU2828899A (en) 1998-01-20 1999-01-20 Lh-receptor gene promoter for tissue-specific gene expression
CA002318660A CA2318660A1 (en) 1998-01-20 1999-01-20 Lh-receptor gene promoter for tissue-specific gene expression
EP99908806A EP1049779A2 (en) 1998-01-20 1999-01-20 Lh-receptor gene promoter for tissue-specific gene expression

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98100919.4 1998-01-20
EP98100919 1998-01-20

Publications (2)

Publication Number Publication Date
WO1999036530A2 WO1999036530A2 (en) 1999-07-22
WO1999036530A3 true WO1999036530A3 (en) 1999-10-21

Family

ID=8231287

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/000361 WO1999036530A2 (en) 1998-01-20 1999-01-20 Lh-receptor gene promoter for tissue-specific gene expression

Country Status (4)

Country Link
EP (1) EP1049779A2 (en)
AU (1) AU2828899A (en)
CA (1) CA2318660A1 (en)
WO (1) WO1999036530A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990013643A2 (en) * 1989-05-05 1990-11-15 Genentech, Inc. Glycoprotein hormone receptor molecules

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990013643A2 (en) * 1989-05-05 1990-11-15 Genentech, Inc. Glycoprotein hormone receptor molecules

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ATGER M ET AL: "Structure of the human luteinizing hormone-choriogonadotropin receptor gene: unusual promoter and 5' non-coding regions.", MOL CELL ENDOCRINOL, JUN 1995, 111 (2) P113-23, IRELAND, XP002072121 *
DAY, RICHARD N. ET AL: "Thyroid hormone-responsive elements of the prolactin gene: evidence for both positive and negative regulation", MOL. ENDOCRINOL. (1989), 3(6), 931-8 CODEN: MOENEN;ISSN: 0888-8809, XP002072122 *
HUHTANIEMI IT ET AL: "THE MURINE LUTEINIZING-HORMONE AND FOLLICLE-STIMULATING-HORMONE RECEPTOR GENES - TRANSCRIPTION INITIATION SITES, PUTATIVE PROMOTER SEQUENCES AND PROMOTER ACTIVITY", MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1992, 88, 55-66, XP002072120 *

Also Published As

Publication number Publication date
AU2828899A (en) 1999-08-02
CA2318660A1 (en) 1999-07-22
EP1049779A2 (en) 2000-11-08
WO1999036530A2 (en) 1999-07-22

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