WO1999032105A1 - Esters of conjugated linoleic acid or conjugated linolenic acid and uses thereof - Google Patents
Esters of conjugated linoleic acid or conjugated linolenic acid and uses thereof Download PDFInfo
- Publication number
- WO1999032105A1 WO1999032105A1 PCT/US1998/027295 US9827295W WO9932105A1 WO 1999032105 A1 WO1999032105 A1 WO 1999032105A1 US 9827295 W US9827295 W US 9827295W WO 9932105 A1 WO9932105 A1 WO 9932105A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- compound
- heptadecadienyl
- cla
- group
- composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/62—Three oxygen atoms, e.g. ascorbic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
- C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
- C07D311/46—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring
- C07D311/50—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring with elements other than carbon and hydrogen in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
- C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
- A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
- A61Q1/06—Lipsticks
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Definitions
- R 2 , R 3 , and R are independently hydrogen or C 1 -C 6 alkyl.
- palmitic acid ester of L-ascorbic acid was prepared in 21.3% yield as about 15:85 mixture of 5- to 6-ester.
- RCOOH linoleic acid
- RCOC1 linoleyl chloride
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Wood Science & Technology (AREA)
- Birds (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU20910/99A AU2091099A (en) | 1997-12-23 | 1998-12-21 | Esters of conjugated linoleic acid or conjugated linolenic acid and uses thereof |
EP98965446A EP1041979A4 (en) | 1997-12-23 | 1998-12-21 | Esters of conjugated linoleic acid or conjugated linolenic acid and uses thereof |
JP2000525096A JP2001526219A (en) | 1997-12-23 | 1998-12-21 | Esters of conjugated linoleic acid and conjugated linolenic acid and uses thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6861597P | 1997-12-23 | 1997-12-23 | |
US60/068,615 | 1997-12-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1999032105A1 true WO1999032105A1 (en) | 1999-07-01 |
Family
ID=22083662
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/027295 WO1999032105A1 (en) | 1997-12-23 | 1998-12-21 | Esters of conjugated linoleic acid or conjugated linolenic acid and uses thereof |
Country Status (5)
Country | Link |
---|---|
US (1) | US6136985A (en) |
EP (1) | EP1041979A4 (en) |
JP (1) | JP2001526219A (en) |
AU (1) | AU2091099A (en) |
WO (1) | WO1999032105A1 (en) |
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000037039A1 (en) * | 1998-12-22 | 2000-06-29 | Unilever Plc | Skin lightening composition |
WO2001005395A1 (en) * | 1999-07-20 | 2001-01-25 | Wisconsin Alumni Research Foundation | Selective inhibition of cyclooxygenase-2 |
WO2001017498A1 (en) * | 1999-09-09 | 2001-03-15 | Pentapharm Ltd. | Use of conjugated linoleic acid (cla) for the topical treatment of cellulite |
WO2001078676A1 (en) * | 2000-04-18 | 2001-10-25 | Unilever Plc | Cosmetic skin conditioning compositions containing high performing retinyl esters |
WO2001079241A1 (en) * | 2000-04-18 | 2001-10-25 | Henkel Kommanditgesellschaft Auf Aktien | Glycoside esters, the production and the use thereof in cosmetics, pharmaceutical products and foodstuff or animal feed |
EP1167340A2 (en) * | 2000-06-19 | 2002-01-02 | Unilever N.V. | Cla-esters |
WO2002038123A1 (en) * | 2000-11-13 | 2002-05-16 | Wadlund As | A skin cream composition |
US6399803B1 (en) | 1999-02-26 | 2002-06-04 | Omegatech, Inc. | Process for separating a triglyceride comprising a docosahexaenoic acid residue from a mixture of triglycerides |
EP1260509A1 (en) * | 2001-05-25 | 2002-11-27 | Derma Developpement S.A.R.L. | Uses of tocopherol esters |
FR2825089A1 (en) * | 2001-05-25 | 2002-11-29 | Derma Dev | Compositions containing tocopherol mono- and polyunsaturated fatty acid esters having a beneficial effect on the skin |
EP1261623A1 (en) * | 2001-01-11 | 2002-12-04 | Chebigen Inc. | New retinol derivatives, the method of preparations and the uses thereof |
EP1268722A2 (en) * | 2000-04-06 | 2003-01-02 | ConLinCo, Inc. | Conjugated linoleic acid compositions |
JP2003505492A (en) * | 1999-07-30 | 2003-02-12 | ユニリーバー・ナームローゼ・ベンノートシヤープ | Skin care composition |
US6600060B2 (en) | 2000-06-19 | 2003-07-29 | Loders Croklaan Bv | CLA-esters |
WO2004044212A1 (en) * | 2002-11-11 | 2004-05-27 | Unilever Plc | Method of producing retinyl esters |
WO2005063230A1 (en) * | 2003-12-30 | 2005-07-14 | Universite Laval | Use of conjugated linolenic acids for reducing body fat mass |
WO2006019186A1 (en) * | 2004-08-18 | 2006-02-23 | Suntory Limited | Skin care products, as well as foods and beverages containing 6-o-pufa ascorbic esters |
US7759096B2 (en) | 2004-01-29 | 2010-07-20 | Stepan Company | Process for enzymatic production of triglycerides |
JP2013253087A (en) * | 1999-07-30 | 2013-12-19 | Unilever Nv | Skin care composition |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060165769A1 (en) * | 2004-09-30 | 2006-07-27 | Hyatt John A | Pharmaceutical formulations containing vitamin E TPGS molecules that solubilize lipophilic drugs without significant efflux inhibition, and use of such formulations |
US20130195780A1 (en) * | 2010-09-17 | 2013-08-01 | Rock Creek Pharmaceuticals, Inc. | Skin Care Products Contianing Anatabine Or Derivative Thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0296483A2 (en) * | 1987-06-26 | 1988-12-28 | F. Hoffmann-La Roche Ag | Preparation of ascorbic acid 6-esters |
US5234702A (en) * | 1992-03-19 | 1993-08-10 | Abbott Laboratories | Antioxidant system for powdered nutritional products |
US5593682A (en) * | 1995-12-29 | 1997-01-14 | Eastman Chemical Company | Skin treating composition |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2474310A1 (en) * | 1980-01-25 | 1981-07-31 | Oreal | STABLE SOLUTION WITH OXIDATION OF VITAMIN F AND JOJOBA OIL AND COSMETIC COMPOSITIONS CONTAINING THE SAME |
JPS57193473A (en) * | 1981-05-26 | 1982-11-27 | Midori Kagaku Kenkyusho:Kk | Vitamin e linoleic acid ester |
US4552897A (en) * | 1983-02-01 | 1985-11-12 | American Cyanamid Company | Salts of 1-(aminodihalophenyl)-2-aminoethanols and antilipogenic compositions prepared therefrom |
US4649158A (en) * | 1983-02-01 | 1987-03-10 | American Cyanamid Company | Novel salts of 1-(aminodihalophenyl)-2-aminoethanols and antilipogenic compositions prepared therefrom |
US5208356A (en) * | 1989-02-17 | 1993-05-04 | Wisconsin Alumni Research Foundation | Octadecadienoic phospholipic esters, antioxidant and mold inhibiting compositions |
US5017614A (en) * | 1989-02-17 | 1991-05-21 | Wisconsin Alumni Research Foundation | Methods of preventing oxidation, quenching singlet oxygen and inhibiting mold growth and novel compositions therefor |
US5288619A (en) * | 1989-12-18 | 1994-02-22 | Kraft General Foods, Inc. | Enzymatic method for preparing transesterified oils |
US5136055A (en) * | 1991-09-03 | 1992-08-04 | Westvaco Corporation | Method for production of dicarboxylic acid and lactone |
US5391373A (en) * | 1992-07-01 | 1995-02-21 | Chanel, Inc. | Skin cream composition |
US5470741A (en) * | 1992-07-22 | 1995-11-28 | Henkel Corporation | Mutant of Geotrichum candidum which produces novel enzyme system to selectively hydrolyze triglycerides |
US5658580A (en) * | 1993-09-09 | 1997-08-19 | Chanel, Inc. | Skin cream composition |
US5445823A (en) * | 1994-10-20 | 1995-08-29 | The Procter & Gamble Company | Dermatological compositions and method of treatment of skin lesions therewith |
MY118354A (en) * | 1995-05-01 | 2004-10-30 | Scarista Ltd | 1,3-propane diol derivatives as bioactive compounds |
DE69609196T3 (en) * | 1995-11-14 | 2006-01-26 | Loders Croklaan B.V. | Process for the preparation of high isomers of conjugated linoleic acid |
US5690918A (en) * | 1995-12-19 | 1997-11-25 | Maybelline, Inc. | Solvent-based non-drying lipstick |
CZ288631B6 (en) * | 1996-01-18 | 2001-08-15 | Galena, A. S. | Therapeutic preparations containing cyclosporin |
US6019990A (en) * | 1997-11-21 | 2000-02-01 | Natural Nutrition Ltd. As | Conjugated linoleic acid delivery system in cosmetic preparations |
GB9828379D0 (en) * | 1998-12-22 | 1999-02-17 | Unilever Plc | Skin care composition |
-
1998
- 1998-12-21 AU AU20910/99A patent/AU2091099A/en not_active Abandoned
- 1998-12-21 JP JP2000525096A patent/JP2001526219A/en active Pending
- 1998-12-21 EP EP98965446A patent/EP1041979A4/en not_active Withdrawn
- 1998-12-21 US US09/217,173 patent/US6136985A/en not_active Expired - Fee Related
- 1998-12-21 WO PCT/US1998/027295 patent/WO1999032105A1/en not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0296483A2 (en) * | 1987-06-26 | 1988-12-28 | F. Hoffmann-La Roche Ag | Preparation of ascorbic acid 6-esters |
US5234702A (en) * | 1992-03-19 | 1993-08-10 | Abbott Laboratories | Antioxidant system for powdered nutritional products |
US5593682A (en) * | 1995-12-29 | 1997-01-14 | Eastman Chemical Company | Skin treating composition |
Non-Patent Citations (1)
Title |
---|
See also references of EP1041979A4 * |
Cited By (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8207225B2 (en) | 1998-03-17 | 2012-06-26 | Aker Biomarine Asa | Conjugated linoleic acid compositions |
WO2000037039A1 (en) * | 1998-12-22 | 2000-06-29 | Unilever Plc | Skin lightening composition |
US6399803B1 (en) | 1999-02-26 | 2002-06-04 | Omegatech, Inc. | Process for separating a triglyceride comprising a docosahexaenoic acid residue from a mixture of triglycerides |
WO2001005395A1 (en) * | 1999-07-20 | 2001-01-25 | Wisconsin Alumni Research Foundation | Selective inhibition of cyclooxygenase-2 |
JP2003505492A (en) * | 1999-07-30 | 2003-02-12 | ユニリーバー・ナームローゼ・ベンノートシヤープ | Skin care composition |
JP2013253087A (en) * | 1999-07-30 | 2013-12-19 | Unilever Nv | Skin care composition |
WO2001017498A1 (en) * | 1999-09-09 | 2001-03-15 | Pentapharm Ltd. | Use of conjugated linoleic acid (cla) for the topical treatment of cellulite |
KR100703142B1 (en) * | 1999-09-09 | 2007-04-05 | 펜타팜아게 | Use of conjugated linoleic acidcla for the topical treatment of cellulite |
US6953583B1 (en) | 1999-09-09 | 2005-10-11 | Pentapharm Ag | Use of conjugated linoleic acid (CLA) for the topical treatment of cellulite |
JP2004506746A (en) * | 2000-04-06 | 2004-03-04 | コンリンコ, インコーポレイテッド | Conjugated linoleic acid composition |
EP1268722A2 (en) * | 2000-04-06 | 2003-01-02 | ConLinCo, Inc. | Conjugated linoleic acid compositions |
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WO2001079241A1 (en) * | 2000-04-18 | 2001-10-25 | Henkel Kommanditgesellschaft Auf Aktien | Glycoside esters, the production and the use thereof in cosmetics, pharmaceutical products and foodstuff or animal feed |
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WO2005063230A1 (en) * | 2003-12-30 | 2005-07-14 | Universite Laval | Use of conjugated linolenic acids for reducing body fat mass |
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Also Published As
Publication number | Publication date |
---|---|
AU2091099A (en) | 1999-07-12 |
JP2001526219A (en) | 2001-12-18 |
EP1041979A1 (en) | 2000-10-11 |
EP1041979A4 (en) | 2001-10-04 |
US6136985A (en) | 2000-10-24 |
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