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Method and apparatus for collecting hyperconcentrated platelets

Info

Publication number
WO1999012590A8
WO1999012590A8 PCT/US1998/018254 US9818254W WO1999012590A8 WO 1999012590 A8 WO1999012590 A8 WO 1999012590A8 US 9818254 W US9818254 W US 9818254W WO 1999012590 A8 WO1999012590 A8 WO 1999012590A8
Authority
WO
Grant status
Application
Patent type
Prior art keywords
fluid
platelets
chamber
collecting
hyperconcentrated
Prior art date
Application number
PCT/US1998/018254
Other languages
French (fr)
Other versions
WO1999012590A1 (en )
Inventor
Larry Joe Dumont
Linda A Taylor
Geert Vanwaeg
Original Assignee
Cobe Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3618Magnetic separation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/362Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits changing physical properties of target cells by binding them to added particles to facilitate their subsequent separation from other cells, e.g. immunoaffinity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3627Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
    • A61M1/3633Blood component filters, e.g. leukocyte filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0471Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with additional elutriation separation of different particles

Abstract

The instant invention relates to a method and the apparatus for collecting a hyperconcentrated platelet product. A fluid containing platelets and other particles flows into a fluid chamber at a flow rate. The flow rate of the fluid is selected to retain the majority of the platelets in the fluid chamber in a saturated bed. The platelets are collected from the fluid chamber without collecting the other particles to form a hyperconcentrated other particle reduced platelet product.
PCT/US1998/018254 1995-04-18 1998-09-02 Method and apparatus for collecting hyperconcentrated platelets WO1999012590A8 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US08/924,787 1997-09-05
US08924787 US6022306A (en) 1995-04-18 1997-09-05 Method and apparatus for collecting hyperconcentrated platelets

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE1998632472 DE69832472T2 (en) 1997-09-05 1998-09-02 A method of gain from hyper concentrated platelets
CA 2270202 CA2270202A1 (en) 1997-09-05 1998-09-02 Method and apparatus for collecting hyperconcentrated platelets
JP51561799A JP2002501422A (en) 1997-09-05 1998-09-02 How to collect a high platelet concentrate and equipment
EP19980944689 EP0961622B1 (en) 1997-09-05 1998-09-02 Method for collecting hyperconcentrated platelets
DE1998632472 DE69832472D1 (en) 1997-09-05 1998-09-02 A method of gain from hyper concentrated platelets

Publications (2)

Publication Number Publication Date
WO1999012590A1 true WO1999012590A1 (en) 1999-03-18
WO1999012590A8 true true WO1999012590A8 (en) 1999-09-02

Family

ID=25450729

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/018254 WO1999012590A8 (en) 1995-04-18 1998-09-02 Method and apparatus for collecting hyperconcentrated platelets

Country Status (6)

Country Link
US (1) US6022306A (en)
JP (1) JP2002501422A (en)
CA (1) CA2270202A1 (en)
DE (2) DE69832472D1 (en)
EP (1) EP0961622B1 (en)
WO (1) WO1999012590A8 (en)

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Also Published As

Publication number Publication date Type
WO1999012590A1 (en) 1999-03-18 application
EP0961622B1 (en) 2005-11-23 grant
JP2002501422A (en) 2002-01-15 application
CA2270202A1 (en) 1999-03-18 application
US6022306A (en) 2000-02-08 grant
EP0961622A1 (en) 1999-12-08 application
DE69832472D1 (en) 2005-12-29 grant
DE69832472T2 (en) 2006-07-20 grant

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