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WO1999011268A1 - Neovascularization promoters and neovascularization potentiators - Google Patents

Neovascularization promoters and neovascularization potentiators

Info

Publication number
WO1999011268A1
WO1999011268A1 PCT/JP1998/003820 JP9803820W WO1999011268A1 WO 1999011268 A1 WO1999011268 A1 WO 1999011268A1 JP 9803820 W JP9803820 W JP 9803820W WO 1999011268 A1 WO1999011268 A1 WO 1999011268A1
Authority
WO
Grant status
Application
Patent type
Prior art keywords
neovascularization
potentiators
promoters
pyridazinone
effects
Prior art date
Application number
PCT/JP1998/003820
Other languages
English (en)
French (fr)
Inventor
Yasuhiro Egi
Hideaki Kido
Kazutaka Hayashi
Yoshiji Kubo
Norifumi Nakamura
Original Assignee
Yoshitomi Pharmaceutical Industries, Ltd.
Nissan Chemical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
PCT/JP1998/003820 1997-08-28 1998-08-26 Neovascularization promoters and neovascularization potentiators WO1999011268A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP23264497 1997-08-28
JP9/232644 1997-08-28

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US09486327 US6284758B1 (en) 1997-08-28 1998-08-26 Angiogenesis promoters and angiogenesis potentiators
DE1998632089 DE69832089D1 (de) 1997-08-28 1998-08-26 Mittel zur förderung und verstärkung der neovaskularisierung
KR20007001968A KR100559192B1 (ko) 1997-08-28 1998-08-26 혈관신생 촉진제 및 혈관신생 작용증강제
JP2000508370A JP4352613B2 (ja) 1997-08-28 1998-08-26 血管新生促進剤及び血管新生作用増強剤
CA 2301852 CA2301852C (en) 1997-08-28 1998-08-26 Angiogenesis promoters and angiogenesis potentiators
EP19980940584 EP1025847B1 (en) 1997-08-28 1998-08-26 Neovascularization promoters and neovascularization potentiators
DE1998632089 DE69832089T2 (de) 1997-08-28 1998-08-26 Mittel zur förderung und verstärkung der neovaskularisierung

Publications (1)

Publication Number Publication Date
WO1999011268A1 true true WO1999011268A1 (en) 1999-03-11

Family

ID=16942531

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP1998/003820 WO1999011268A1 (en) 1997-08-28 1998-08-26 Neovascularization promoters and neovascularization potentiators

Country Status (10)

Country Link
US (1) US6284758B1 (ja)
EP (1) EP1025847B1 (ja)
JP (1) JP4352613B2 (ja)
KR (1) KR100559192B1 (ja)
CN (1) CN1142779C (ja)
CA (1) CA2301852C (ja)
DE (2) DE69832089T2 (ja)
DK (1) DK1025847T3 (ja)
ES (1) ES2247716T3 (ja)
WO (1) WO1999011268A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008105260A1 (ja) * 2007-02-28 2008-09-04 Ltt Bio-Pharma Co., Ltd. 下肢切断手術の予後を改善する治療剤

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000033845A1 (fr) * 1998-12-07 2000-06-15 Nissan Chemical Industries, Ltd. Agent therapeutique pour le traitement de la dyserection
CN1897952B (zh) * 2003-12-26 2010-12-08 日产化学工业株式会社;大正制药株式会社 中性白细胞增多抑制剂
KR20070029133A (ko) * 2004-02-09 2007-03-13 닛산 가가쿠 고교 가부시키 가이샤 혈관 내막 비후 억제약
CA2615452C (en) 2005-07-15 2015-03-31 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
ES2540059T3 (es) 2006-04-26 2015-07-08 Micell Technologies, Inc. Recubrimientos que contienen múltiples fármacos
CA2667228C (en) 2006-10-23 2015-07-14 Micell Technologies, Inc. Holder for electrically charging a substrate during coating
US9737642B2 (en) 2007-01-08 2017-08-22 Micell Technologies, Inc. Stents having biodegradable layers
EP2170418B1 (en) 2007-05-25 2016-03-16 Micell Technologies, Inc. Polymer films for medical device coating
US8685432B2 (en) * 2008-03-25 2014-04-01 University Of Utah Research Foundation Controlled release tissue graft combination biomaterials
WO2009146209A1 (en) 2008-04-17 2009-12-03 Micell Technologies, Inc. Stents having bioabsorbable layers
US9510856B2 (en) 2008-07-17 2016-12-06 Micell Technologies, Inc. Drug delivery medical device
EP2313122A4 (en) 2008-07-17 2013-10-30 Micell Technologies Inc Drug delivery medical device
US8834913B2 (en) 2008-12-26 2014-09-16 Battelle Memorial Institute Medical implants and methods of making medical implants
CA2759015C (en) 2009-04-17 2017-06-20 James B. Mcclain Stents having controlled elution
US8795762B2 (en) 2010-03-26 2014-08-05 Battelle Memorial Institute System and method for enhanced electrostatic deposition and surface coatings
WO2011133183A1 (en) 2010-04-20 2011-10-27 University Of Utah Research Foundation Phase separation sprayed scaffold
EP2953581A4 (en) 2013-02-05 2016-11-30 Univ Utah Res Found Implantable devices for bone or joint defects

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991016314A1 (fr) * 1990-04-25 1991-10-31 Nissan Chemical Industries Ltd. Derive de pyridazinone
JPH07252237A (ja) * 1994-01-25 1995-10-03 Nissan Chem Ind Ltd ピリダジノン誘導体
JPH07285869A (ja) * 1994-02-22 1995-10-31 Green Cross Corp:The トロンボキサンa2関与疾患の予防・治療剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2063055A1 (en) * 1991-05-22 1992-11-23 Jacob Eyal Peptides having thrombospondin-like activity and their therapeutic use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991016314A1 (fr) * 1990-04-25 1991-10-31 Nissan Chemical Industries Ltd. Derive de pyridazinone
JPH07252237A (ja) * 1994-01-25 1995-10-03 Nissan Chem Ind Ltd ピリダジノン誘導体
JPH07285869A (ja) * 1994-02-22 1995-10-31 Green Cross Corp:The トロンボキサンa2関与疾患の予防・治療剤

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
AHMED A., ET AL.: "ROLE OF VEGF RECEPTOR-1 (FLT-1) IN MEDIATING CALCIUM-DEPENDENT NITRIC OXIDE RELEASE AND LIMITING DNA SYNTHESIS IN HUMAN TROPHOBLAST CELLS.", LABORATORY INVESTIGATION, NATURE PUBLISHING GROUP, THE UNITED STATES AND CANADIAN ACADEMY OF PATHOLOGY, INC., vol. 76., no. 06., 1 January 1997 (1997-01-01), The United States and Canadian Academy of Pathology, Inc., pages 779 - 791., XP002914614, ISSN: 0023-6837 *
See also references of EP1025847A4 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008105260A1 (ja) * 2007-02-28 2008-09-04 Ltt Bio-Pharma Co., Ltd. 下肢切断手術の予後を改善する治療剤

Also Published As

Publication number Publication date Type
DE69832089D1 (de) 2005-12-01 grant
DK1025847T3 (da) 2006-02-13 grant
EP1025847A1 (en) 2000-08-09 application
CA2301852A1 (en) 1999-03-11 application
CN1142779C (zh) 2004-03-24 grant
CA2301852C (en) 2007-07-10 grant
DE69832089T2 (de) 2006-07-20 grant
EP1025847B1 (en) 2005-10-26 grant
JP4352613B2 (ja) 2009-10-28 grant
KR100559192B1 (ko) 2006-03-13 grant
KR20010023331A (ko) 2001-03-26 application
ES2247716T3 (es) 2006-03-01 grant
EP1025847A4 (en) 2003-01-08 application
US6284758B1 (en) 2001-09-04 grant
CN1277553A (zh) 2000-12-20 application

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