WO1998057540A1 - Repellent pest control system - Google Patents

Repellent pest control system Download PDF

Info

Publication number
WO1998057540A1
WO1998057540A1 PCT/EP1998/003727 EP9803727W WO9857540A1 WO 1998057540 A1 WO1998057540 A1 WO 1998057540A1 EP 9803727 W EP9803727 W EP 9803727W WO 9857540 A1 WO9857540 A1 WO 9857540A1
Authority
WO
WIPO (PCT)
Prior art keywords
pest control
dogs
active ingredient
triphenyl phosphate
polymer
Prior art date
Application number
PCT/EP1998/003727
Other languages
French (fr)
Inventor
Catherine Focheux
Marie-Pierre Puech
Robert Killick-Kendrick
Mireille Killick-Kendrick
Original Assignee
Hoechst Roussel Vet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8229783&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO1998057540(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to AT98937504T priority Critical patent/ATE239369T1/en
Priority to ES98937504.3T priority patent/ES2198736T7/en
Priority to CA002294325A priority patent/CA2294325A1/en
Priority to EP98937504.3A priority patent/EP1022944B3/en
Priority to DE69814437T priority patent/DE69814437T2/en
Priority to HU0003004A priority patent/HU229548B1/en
Priority to DK98937504T priority patent/DK1022944T3/en
Application filed by Hoechst Roussel Vet filed Critical Hoechst Roussel Vet
Priority to AU86275/98A priority patent/AU8627598A/en
Priority to BR9811269-4A priority patent/BR9811269A/en
Priority to US09/446,340 priority patent/US6413532B1/en
Priority to MXPA99011662A priority patent/MXPA99011662A/en
Priority to IL13354998A priority patent/IL133549A/en
Publication of WO1998057540A1 publication Critical patent/WO1998057540A1/en
Priority to NO996289A priority patent/NO996289L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof

Definitions

  • the invention relates to a repellent pest control system.
  • a subject of the invention is a repellent pest control system for the controlled release of a pest control active ingredient from a polymer matrix which comprises : a vinyl polymer a liquid plasticizer for said polymer, said plasticizer being present in the maximum amount possible and still maintain a dry and flowable blend of plasticizer and polymer and triphenyl phosphate, said triphenyl phosphate being present in an amount sufficient to serve as a carrier for said active ingredient.
  • a subject of the invention is a system wherein the polymer is a vinyl chloride polymer or copolymer, and/or a system wherein the liquid plasticizer is an adipic ester or a phthalic ester, and/or a system wherein the amount of triphenyl phosphate is within the range of about 10 to 35 percent by weight of the total system.
  • the pest system may be produced as described in the Europeen Patent Applicaton 539295.
  • a solid polymeric composition for the release of a pest control active ingredient which comprises a vinyl polymer, a liquid plasticize and a pest control active ingredient, the improvement which comprises including triphenyl phosphate in said composition, said triphenyl phosphate being present in an amount sufficient to serve as a carrier for said active ingredient and precisely a composition wherein the amount of triphenyl phosphate is from about 10 to 35 percent by weight of the composition.
  • a more particular subject of the invention is the system wherein the active ingredient is pyrethroid.
  • the pyrethroid may be chosen from the following compounds : deltamethrin, acrinathrin, tralomethrin, perme- thrin, cypermethrin, alphameth in, cyhalothrin, fenvalerate, cyfluthrin, flucythrin, flucythrinate, fluvalinate, fenpropathrin, bifenthrin, esfenvalerate, alphacypermethrin, betacyfluthrin, lambdacyalothrin, taufluvalinate or sila- fluofen.
  • the repellent system according to the invention enables external parasites to be combatted; it is applicable, in particular, to the control of acaridae, for example, ticks and scabies, the warble, insects such as lice, bugs and different kinds of biting and stinging flies.
  • a more particular subject of the invention is a repellent pest control system wherein the pests are phlebotomine sandflies.
  • Canine leishmaniasis caused by Leishmania infantum is highly prevalent in all countries of the Mediterranean subregion and in many countries of Latin America, notably Brazil. In most foci it is probable that all dogs are bitten by an infected sandfly in the first transmission season. After an incubation period of up to one year, or even more, some dogs develop clinical signs of leishmaniasis and rising titres of antibodies, whereas others mount an effective cell mediated immune response with low or negative titres of antibodies, and no signs of disease.
  • the prevalence rates of serologically positive dogs in the Mediterranean subregion are commonly around 10 % but may exceed 30 %. In southern Spain, half of the dogs seen by veterinarians have leishmaniasis. Once signs of the disease are apparent, untreated dogs invariably die. Treatment (for example with pentavalent antimonials) is expensive and is almost always followed by a relapse. No vaccines are available.
  • canine leishmaniasis as a veterinary problem is overshadowed by the fact that dogs are reservoirs of visceral leishmaniasis for the human population and attempts to control canine leishmaniasis seem always to be aimed at reducing the risk of infection to man rather than dogs.
  • the results of control campaigns have been disappointing.
  • insecticide spraying or houses will not greatly decrease the risk of infection, and expensive campaigns to reduce the reservoir of infection by culling seologically positive dogs have met with owner resistance and only limited success.
  • the closely related parasite (Leishmania chagasi) is carried by different species of sandflies (principally Lutzo yia longipalpis, but also Lu. evansi in parts of Colombia and Venezuela) .
  • sandflies principally Lutzo yia longipalpis, but also Lu. evansi in parts of Colombia and Venezuela.
  • dogs are commonly infected, but the prevalence of the human disease is generally higher, notably in Brazil.
  • the principal vector in the Neotropics is present in enormous numbers in and around houses and feeds on any available mammal or bird. It has a wide distribution and has proved impossible to control.
  • the repellent pest control system is a dog collar, for example a dog collar comprising 2 to 6 g of deltamethrin per 100 g of collar with an optimum of 4 g of deltamethrin per 100 g of collar.
  • Another subject of the invention is the protection of dog from bites of phlebotomine sandflies by deltamethrin collar for the control of canine leishmaniasis.
  • Deltamethrin dog collars protect dogs from almost all the bites of phlebotomine sandflies for a period up to and including 34 weeks. While absolute protection from leishma- niasis cannot be expected, the risk to dogs wearing collars should be reduced to a negligible level compared to dogs without collars. In addition, when confined with collared dogs, a high proportion of flies die within two hours. It is concluded that the collars have strong anti-feeding and lethal effects to phlebotomine sandflies lasting for a complete sandfly season.
  • the collars could be used in two ways. Firstly, they offer a means for owners to protect their dogs from canine leishmaniasis. Secondly, they provide a unique tool in the control of human visceral leishmaniasis with dogs as the main source of infection. Because the collars break the contact between dogs and sandflies, it is probable that their universal use would stop the circulation of the parasite and the human disease would disappear.
  • Dog collars were made from the following formulation (percent by weight) :
  • Epoxidized soya bean oil 0.950 g
  • Triphenyl phosphate 5.890 g Titanium dioxide 0.285 g
  • Dog collars consisted of a 48 cm strip of polyvinyl chloride (PVC) weighing 20 g impregnated with deltamethrin 40 mg/g.
  • PVC polyvinyl chloride
  • Live flies were collected and maintained for ⁇ 20 h at 19-24 °C in suspended gauze 16 cm cubic cages, to allow for the possibility that some flies with the collared dogs might have received a low dose of insecticide causing delayed mortality. After the holding period, they were scored as either (i) live and engorged, (ii) live and unengorged, (iii) dead and engorged, or (iv) dead and inengorged. Dogs, identified by tattooed numbers, were female laboratory bred beagles aged 7 months when the experiments started. Five collared dogs were separately housed outside in large enclosures with kennel shelters. Two control dogs without collars were similarly housed together in another outside enclosure, 25 m from the collared dogs.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Toxicology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Catching Or Destruction (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

A repellent solid pest control system which includes a polymeric matrix, a liquid plasticizer, a pest control active ingredient and triphenyl phosphate as a carrier for the active ingredient. Protection of dogs from bites of phlebotomine sandflies by using systems according to the inventor for the control of canine leishmaniasis.

Description

Repellent pest control system The invention relates to a repellent pest control system.
A subject of the invention is a repellent pest control system for the controlled release of a pest control active ingredient from a polymer matrix which comprises : a vinyl polymer a liquid plasticizer for said polymer, said plasticizer being present in the maximum amount possible and still maintain a dry and flowable blend of plasticizer and polymer and triphenyl phosphate, said triphenyl phosphate being present in an amount sufficient to serve as a carrier for said active ingredient. In particular a subject of the invention is a system wherein the polymer is a vinyl chloride polymer or copolymer, and/or a system wherein the liquid plasticizer is an adipic ester or a phthalic ester, and/or a system wherein the amount of triphenyl phosphate is within the range of about 10 to 35 percent by weight of the total system.
The pest system may be produced as described in the Europeen Patent Applicaton 539295.
As a preferred system, it can be mentionned in a solid polymeric composition for the release of a pest control active ingredient which comprises a vinyl polymer, a liquid plasticize and a pest control active ingredient, the improvement which comprises including triphenyl phosphate in said composition, said triphenyl phosphate being present in an amount sufficient to serve as a carrier for said active ingredient and precisely a composition wherein the amount of triphenyl phosphate is from about 10 to 35 percent by weight of the composition.
A more particular subject of the invention is the system wherein the active ingredient is pyrethroid. The pyrethroid may be chosen from the following compounds : deltamethrin, acrinathrin, tralomethrin, perme- thrin, cypermethrin, alphameth in, cyhalothrin, fenvalerate, cyfluthrin, flucythrin, flucythrinate, fluvalinate, fenpropathrin, bifenthrin, esfenvalerate, alphacypermethrin, betacyfluthrin, lambdacyalothrin, taufluvalinate or sila- fluofen.
As preferred pyrethroid, it can be mentionned deltamethrin.
The repellent system according to the invention enables external parasites to be combatted; it is applicable, in particular, to the control of acaridae, for example, ticks and scabies, the warble, insects such as lice, bugs and different kinds of biting and stinging flies.
A more particular subject of the invention is a repellent pest control system wherein the pests are phlebotomine sandflies.
Canine leishmaniasis caused by Leishmania infantum is highly prevalent in all countries of the Mediterranean subregion and in many countries of Latin America, notably Brazil. In most foci it is probable that all dogs are bitten by an infected sandfly in the first transmission season. After an incubation period of up to one year, or even more, some dogs develop clinical signs of leishmaniasis and rising titres of antibodies, whereas others mount an effective cell mediated immune response with low or negative titres of antibodies, and no signs of disease. The prevalence rates of serologically positive dogs in the Mediterranean subregion are commonly around 10 % but may exceed 30 %. In southern Spain, half of the dogs seen by veterinarians have leishmaniasis. Once signs of the disease are apparent, untreated dogs invariably die. Treatment (for example with pentavalent antimonials) is expensive and is almost always followed by a relapse. No vaccines are available.
The importance of canine leishmaniasis as a veterinary problem is overshadowed by the fact that dogs are reservoirs of visceral leishmaniasis for the human population and attempts to control canine leishmaniasis seem always to be aimed at reducing the risk of infection to man rather than dogs. However, with the exception of western China where canine leishmaniasis and the human disease were eradicated by the destruction of all dogs, the results of control campaigns have been disappointing. As the vectors are not strongly endophagic (feeding indoors) or endophilic (resting indoors) , insecticide spraying or houses will not greatly decrease the risk of infection, and expensive campaigns to reduce the reservoir of infection by culling seologically positive dogs have met with owner resistance and only limited success.
Among the proven or suspected vector of canine leishmaniasis in the Mediterranean subregion are Phlebotomus perniciosus (France, Spain, Portugal, Maghreb) , P. ariasi (France, Spain, Portugal, Morocco) , P. perfiliewi (Italy,
Greece, Serbia, Magreb) , P. tobbi (Greece, Cyprus, Syria) , P. neglectus (Greece) , P. syriacus (Syria, Lebanon, Israel) and P. langeroni (Egypt) . These closely related flies have a similar biology. The female flies (but not the males) take blood meals from any available mammal, with a preference for canids. They bite at night the highest activity outside. The risk of infection is, therefore, somewhat higher outdoors than indoors.
In Central and South America, the closely related parasite (Leishmania chagasi) is carried by different species of sandflies (principally Lutzo yia longipalpis, but also Lu. evansi in parts of Colombia and Venezuela) . As in the Mediterranean subregion, dogs are commonly infected, but the prevalence of the human disease is generally higher, notably in Brazil. The principal vector in the Neotropics is present in enormous numbers in and around houses and feeds on any available mammal or bird. It has a wide distribution and has proved impossible to control.
As a prefered subject of the invention, the repellent pest control system is a dog collar, for example a dog collar comprising 2 to 6 g of deltamethrin per 100 g of collar with an optimum of 4 g of deltamethrin per 100 g of collar.
Another subject of the invention is the protection of dog from bites of phlebotomine sandflies by deltamethrin collar for the control of canine leishmaniasis.
Deltamethrin dog collars protect dogs from almost all the bites of phlebotomine sandflies for a period up to and including 34 weeks. While absolute protection from leishma- niasis cannot be expected, the risk to dogs wearing collars should be reduced to a negligible level compared to dogs without collars. In addition, when confined with collared dogs, a high proportion of flies die within two hours. It is concluded that the collars have strong anti-feeding and lethal effects to phlebotomine sandflies lasting for a complete sandfly season.
The collars could be used in two ways. Firstly, they offer a means for owners to protect their dogs from canine leishmaniasis. Secondly, they provide a unique tool in the control of human visceral leishmaniasis with dogs as the main source of infection. Because the collars break the contact between dogs and sandflies, it is probable that their universal use would stop the circulation of the parasite and the human disease would disappear.
The following examples illustrate the invention and show how it can be implemented. EXAMPLE 1 :
Dog collars were made from the following formulation (percent by weight) :
PVC (med. mol. wt.) 40.6
Stabilizer (CZ19A) 0.4
Epoxidized oil 5.0
Dioctyl adipate 18.0 Triphenyl phosphate 32.0
Deltamethrin 4.0
EXAMPLE 2 :
With an average metric mass of 0.390 g/cm, a collar cut to 48 cm weighs 18.72 g. For simplification purposes this weight is rounded off to 19 g. Considering that the concentration of deltamethrin in the collar is 40 mg/g then the unit formulae are the following.
Name of ingredient Unit formula for collar
Deltamethrin 0.760 g Organo Ca-Zn soap blend 0.095 g
Epoxidized soya bean oil 0.950 g
Diisooctyl adipate 3.420 g
Triphenyl phosphate 5.890 g Titanium dioxide 0.285 g
Polyvinyl chloride q.s. 19.000 g
Materials and methods
Dog collars, consisted of a 48 cm strip of polyvinyl chloride (PVC) weighing 20 g impregnated with deltamethrin 40 mg/g.
Experimental procedure, 1, 2, 3, 4, 13, 20, 26 and 34 weeks after attachment of deltamethrin-impregnated collars, two experimental dogs were sedated and put inside separate nets for 2 h with 160-200 female (and about 25 male) sandflies, Phlebotomus perniciosus. Two other dogs without collars were similarly exposed as controls. At the end of the 2 h exposure period the dogs were removed and all dead flies were collected, kept at room temperature until the following day (in case they recovered after knock-down) and then counted, examined with a dissecting microscope and recorded as engorged or unengorged. Live flies were collected and maintained for ~ 20 h at 19-24 °C in suspended gauze 16 cm cubic cages, to allow for the possibility that some flies with the collared dogs might have received a low dose of insecticide causing delayed mortality. After the holding period, they were scored as either (i) live and engorged, (ii) live and unengorged, (iii) dead and engorged, or (iv) dead and inengorged. Dogs, identified by tattooed numbers, were female laboratory bred beagles aged 7 months when the experiments started. Five collared dogs were separately housed outside in large enclosures with kennel shelters. Two control dogs without collars were similarly housed together in another outside enclosure, 25 m from the collared dogs. To ensure there was no variation in the responses of the dogs to sandfly bites that could disturb the flies, they were all sedated before each experiment with Keta ine® and Dor itor® (SmithKline Beecham) given intravenously as a mixture of 0.6- 0.9 ml of each drug per 10 kg body weight (depending on the animal's reaction on a previous occasion). At these doses, sedation was satisfactory for the whole 2 h period of exposure. Sandflies were from a closed laboratory colony of Phlebotomus perniciosus originating from Spain. The age of sandflies put into nets with dogs was 7-15 days, i.e. the age when it was found that females of this species feed most readily in the conditions of the experiments. Flies of similar age were counted from stock cages (cubic 45 cm) and distributed with an aspirator into four small cages (cubic 16 cm) . They were transferred to the nets 15-30 min before the experiments. Any flies dead in the small cages were counted and the number deducted from the total. When opening the zip fasteners at the bottom of the nets to put in and take out dogs, or recapture the flies, lights were put on to attract the flies to the top of the nets. As the dogs were taken out at the end of the exposure, they were examined for dead or feeding flies (which were seldom present) . The people who entered the nets to recover the flies wore overalls to prevent bites. Results :
Anti-feedincf effects of the sandflies recaptured from tests 2-34 weeks after the dogs began wearing deltamethrin- impregnated collars, were demonstrated by the fact that 1911 females had engorged on the collarless (control) dogs and 75 on the dogs with collars.
More than 70 % of female flies engorged on the control dogs at weeks 2-34 compared to < 13 % on the collared dogs. Lethal effect. For sandflies exposed to the dogs 1 week after collars were fitted, before the insecticide from the collars had diffused well over the fur pelt of the dogs, the mortality-rate of sandflies following 2 h exposure was, as expected, the lowest (21 % and 25 %) . From tests in weeks 2-34 the proportions of P. perniciosus dead in nets with collared dogs were 25-64 %, consistently highly significantly greater than 1.1-12.0 % dead in nets with collarless (control) dogs. For each pair of replicate dogs, there was no statistically significant difference in the proportions of flies dead in the nets at the end of 2 h confinement.
Overall mortality of sandflies was < 16 % with control dogs and > 45 % with collared dogs.

Claims

CLAIMS 1) A repellent pest control system for the controlled release of a pest control active ingredient from a polymer matrix which comprises : a vinyl polymer a liquid plasticizer for said polymer, said plasticizer being present in the maximum amount possible but still maintaining a dry and flowable blend of plasticizer and polymer and triphenyl phosphate, said triphenyl phosphate being present in an amount sufficient to serve as a carrier for said active ingredient.
2) A system according to claim 1 wherein the polymer is a vinyl chloride polymer or copolymer.
3) A system according to claim 2 wherein the liquid plasticizer is an adipic ester or a phthalic ester.
4) A system according to claim 1 wherein the amount of triphenyl phosphate is within the range of about 10 to 35 percent by weight of the total system.
5) A solid polymeric composition for the release of a pest control active ingredient which comprises a vinyl polymer, a liquid plasticize and a pest control active ingredient, the improvement comprising the inclusion of triphenyl phosphate in said composition, said triphenyl phosphate being present in an amout sufficient to serve as a carrier for said active ingredient.
6) Composition according to claim 5 wherein the amount of triphenyl phosphate is from about 10 to 35 percent by weight of the composition.
7) A repellent pest control system according to any of claims 1 to 6 wherein the active ingredient is a pyrethroid. 8) A repellent pest control system according to claim 7 vherein the pyrethroid is deltamethrin.
9) A repellent pest control system according to any of claims 1 to 7 wherein the pest is phlebotomine sandflies.
10) A repellent pest control system according to any of claims 1 to 9 in the form of a dog collar.
11) A dog collar according to claim 10 comprising 2 to 6 g of deltamethrin for 100 g.
12) Protection of dogs from bites of phlebotomine sandflies by deltamethrin collar according to claim 11 for the control of canine leishmaniasis.
PCT/EP1998/003727 1997-06-18 1998-06-16 Repellent pest control system WO1998057540A1 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IL13354998A IL133549A (en) 1997-06-18 1998-06-16 Repellent pest control system
DK98937504T DK1022944T3 (en) 1997-06-18 1998-06-16 Device for displacement of pests
CA002294325A CA2294325A1 (en) 1997-06-18 1998-06-16 Repellent pest control system
EP98937504.3A EP1022944B3 (en) 1997-06-18 1998-06-16 Repellent pest control system
DE69814437T DE69814437T2 (en) 1997-06-18 1998-06-16 DEVICE FOR DISCARDING Pests
HU0003004A HU229548B1 (en) 1997-06-18 1998-06-16 Repellent pest control system
AU86275/98A AU8627598A (en) 1997-06-18 1998-06-16 Repellent pest control system
AT98937504T ATE239369T1 (en) 1997-06-18 1998-06-16 DEVICE FOR REPELLING PESTS
ES98937504.3T ES2198736T7 (en) 1997-06-18 1998-06-16 Pest control repellent system
BR9811269-4A BR9811269A (en) 1997-06-18 1998-06-16 Pest repellent control system
US09/446,340 US6413532B1 (en) 1997-06-18 1998-06-16 Repellent pest control system
MXPA99011662A MXPA99011662A (en) 1997-06-18 1998-06-16 Repellent pest control system.
NO996289A NO996289L (en) 1997-06-18 1999-12-17 Pest control system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97401390.6 1997-06-18
EP97401390A EP0885563A1 (en) 1997-06-18 1997-06-18 Repellent pest control system

Publications (1)

Publication Number Publication Date
WO1998057540A1 true WO1998057540A1 (en) 1998-12-23

Family

ID=8229783

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/003727 WO1998057540A1 (en) 1997-06-18 1998-06-16 Repellent pest control system

Country Status (24)

Country Link
US (1) US6413532B1 (en)
EP (2) EP0885563A1 (en)
AR (1) AR013353A1 (en)
AT (1) ATE239369T1 (en)
AU (1) AU8627598A (en)
BR (1) BR9811269A (en)
CA (1) CA2294325A1 (en)
CO (1) CO5050347A1 (en)
DE (1) DE69814437T2 (en)
DK (1) DK1022944T3 (en)
DZ (1) DZ2525A1 (en)
ES (1) ES2198736T7 (en)
HU (1) HU229548B1 (en)
IL (1) IL133549A (en)
JO (1) JO2061B1 (en)
MA (1) MA24595A1 (en)
MX (1) MXPA99011662A (en)
NO (1) NO996289L (en)
PE (1) PE100999A1 (en)
PT (1) PT1022944E (en)
TN (1) TNSN98091A1 (en)
TR (1) TR199903133T2 (en)
WO (1) WO1998057540A1 (en)
ZA (1) ZA985310B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011149000A (en) * 2009-12-25 2011-08-04 Sumitomo Chemical Co Ltd Insect pest control resin composition
EP2529628A1 (en) * 2011-05-30 2012-12-05 Konig do Brasil Ltda. A controlled-release pesticide system for a composition

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7007861B2 (en) 2000-06-08 2006-03-07 S.C. Johnson & Son, Inc. Methods and personal protection devices for repelling insects
BRPI1100016A2 (en) * 2011-02-14 2012-06-12 Konig Do Brasil Ltda a pesticide controlled release composition system containing deltamethrin, propoxur and insect repellent
FR3002232B1 (en) 2013-02-15 2015-03-27 Ab7 Innovation POLYMERIC SUPPORT FOR DISPENSING NATURALLY CRYSTALLINE SUBSTANCE AND PROCESS FOR OBTAINING SAME

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5437869A (en) * 1991-10-24 1995-08-01 Kelley; Donald W. Pest control system

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5437869A (en) * 1991-10-24 1995-08-01 Kelley; Donald W. Pest control system

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, vol. 13, no. 3, 1995, pages 178 - 181 *
DATABASE MEDLINE US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; 1997, KILLICK-KENDRICK ET AL.: "Protection of dogs from bites of phlebotomine sandflies by deltamethrin collars for control of canine leishmaniasis", XP002046200 *
DATABASE MEDLINE US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; XIONG ET AL.: "Studies on the deltamethrin -medicated bath of domestic dogs for interrupting visceral leishmaniasis transmision", XP002046201 *
MEDICAL AND VETERINARY ENTOMOLOGY, vol. 11, no. 2, April 1997 (1997-04-01), pages 105 - 111 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011149000A (en) * 2009-12-25 2011-08-04 Sumitomo Chemical Co Ltd Insect pest control resin composition
EP2529628A1 (en) * 2011-05-30 2012-12-05 Konig do Brasil Ltda. A controlled-release pesticide system for a composition

Also Published As

Publication number Publication date
HU229548B1 (en) 2014-01-28
DK1022944T3 (en) 2003-08-25
JO2061B1 (en) 2000-05-21
DZ2525A1 (en) 2003-02-01
EP1022944B1 (en) 2003-05-07
HUP0003004A3 (en) 2003-02-28
ES2198736T3 (en) 2004-02-01
EP1022944B3 (en) 2017-04-26
ATE239369T1 (en) 2003-05-15
PE100999A1 (en) 1999-10-13
AU8627598A (en) 1999-01-04
CO5050347A1 (en) 2001-06-27
IL133549A (en) 2004-12-15
DE69814437T2 (en) 2004-01-15
NO996289D0 (en) 1999-12-17
US6413532B1 (en) 2002-07-02
PT1022944E (en) 2003-08-29
ZA985310B (en) 1999-06-18
TNSN98091A1 (en) 2005-03-15
DE69814437D1 (en) 2003-06-12
EP0885563A1 (en) 1998-12-23
TR199903133T2 (en) 2000-05-22
ES2198736T7 (en) 2017-08-24
EP1022944A1 (en) 2000-08-02
IL133549A0 (en) 2001-04-30
MA24595A1 (en) 1999-04-01
CA2294325A1 (en) 1998-12-23
AR013353A1 (en) 2000-12-27
BR9811269A (en) 2000-07-18
MXPA99011662A (en) 2002-07-22
HUP0003004A2 (en) 2001-02-28
NO996289L (en) 2000-02-15

Similar Documents

Publication Publication Date Title
Killick‐Kendrick et al. Protection of dogs from bites of phlebotomine sandflies by deltamethrin collars for control of canine leishmaniasis
TW592634B (en) Collar containing a novel gel formulation to control arthropod infestation of animals
US5296227A (en) Attractant decoy for controlling bont ticks
PL186883B1 (en) Method of fighting against pests attacking honey-yielding bee colonies
EP3217994B1 (en) Compositions and methods for attracting mosquitoes and repelling sand flies
US6413532B1 (en) Repellent pest control system
JPH0782105A (en) Durable pyriproxyphene composition for suppressing parasite
AU768388B2 (en) An improved process for combating parasitosis in bee colonies
EP2529628B1 (en) A controlled-release pesticide system for a composition
US10653141B2 (en) Compositions and methods for attracting mosquitoes and repelling sand flies
Reifenrath Laboratory and field studies of C8910, a fatty-acid–based insect/arthropod repellent and biopesticide
US20220167613A1 (en) Choline chloride adjuvant for fatty acid based biopesticide
KR100479254B1 (en) How to curb bee bee infection
WO2000040084A2 (en) Pet medallion
JPS63141902A (en) Detoxified sorptive vermicidal resin composition for controlling vermins in soil and preparation of same
JP3174175B2 (en) Ant venom containing venom
WO2017214272A1 (en) Control of pests in honey bee hives
JPS58192801A (en) Parasiticide
Dusbábek 1.1 PRESENT POSSIBILITIES AND PERSPECTIVES OF INTEGRATED CONTROL OF ARGASID TICKS (IXODOIDEA: ARGASIDAE)
WO2012109715A1 (en) Pvc-based composition in combination with triphenyl and cresyl diphenyl phosphates for the controlled release of pesticides
JPH05221815A (en) Repellent against harmful organism

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 133549

Country of ref document: IL

AK Designated states

Kind code of ref document: A1

Designated state(s): AL AU BA BB BG BR CA CN CU CZ EE GE GW HU ID IL IS JP KP KR LC LK LR LT LV MG MK MN MX NO NZ PL RO SG SI SK SL TR TT UA US UZ VN YU

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 86275/98

Country of ref document: AU

Ref document number: 501381

Country of ref document: NZ

WWE Wipo information: entry into national phase

Ref document number: 1998937504

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2294325

Country of ref document: CA

Ref document number: 2294325

Country of ref document: CA

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: PA/a/1999/011662

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 1999/03133

Country of ref document: TR

NENP Non-entry into the national phase

Ref document number: 1999503771

Country of ref document: JP

WWP Wipo information: published in national office

Ref document number: 1998937504

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 09446340

Country of ref document: US

WWG Wipo information: grant in national office

Ref document number: 1998937504

Country of ref document: EP