WO1998051666A3 - Process for the preparation of an oxirane, aziridine or cyclopropane - Google Patents
Process for the preparation of an oxirane, aziridine or cyclopropane Download PDFInfo
- Publication number
- WO1998051666A3 WO1998051666A3 PCT/GB1998/001289 GB9801289W WO9851666A3 WO 1998051666 A3 WO1998051666 A3 WO 1998051666A3 GB 9801289 W GB9801289 W GB 9801289W WO 9851666 A3 WO9851666 A3 WO 9851666A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- aryl
- alkyl
- heteroaromatic
- cycloalkyl
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/22—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
- C07D203/24—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/02—Preparation by ring-closure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/02—Synthesis of the oxirane ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D303/46—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by amide or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/06—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/08—Bridged systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/903—Diazo reactions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Epoxy Compounds (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU72251/98A AU7225198A (en) | 1997-05-09 | 1998-05-01 | Process for the preparation of an oxirane, aziridine or cyclopropane |
EP98919377A EP0983236B1 (en) | 1997-05-09 | 1998-05-01 | Process for the preparation of an oxirane, aziridine or cyclopropane |
JP54889098A JP2001527556A (en) | 1997-05-09 | 1998-05-01 | Process for producing oxirane, aziridine or cyclopropane |
US09/423,428 US6559323B1 (en) | 1997-05-09 | 1998-05-01 | Process for the preparation of an oxirane, aziridine or cyclopropane |
AT98919377T ATE249431T1 (en) | 1997-05-09 | 1998-05-01 | METHOD FOR PRODUCING OXIRANS, AZIRIDINES AND CYCLOPROPANES |
DE69818039T DE69818039T2 (en) | 1997-05-09 | 1998-05-01 | METHOD FOR PRODUCING OXIRANES, AZIRIDINES AND CYCLOPROPANES |
CA002289755A CA2289755A1 (en) | 1997-05-09 | 1998-05-01 | Process for the preparation of an oxirane, aziridine or cyclopropane |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9709528.5 | 1997-05-09 | ||
GBGB9709528.5A GB9709528D0 (en) | 1997-05-09 | 1997-05-09 | Chemical process |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998051666A2 WO1998051666A2 (en) | 1998-11-19 |
WO1998051666A3 true WO1998051666A3 (en) | 1999-02-25 |
Family
ID=10812123
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1998/001289 WO1998051666A2 (en) | 1997-05-09 | 1998-05-01 | Process for the preparation of an oxirane, aziridine or cyclopropane |
Country Status (12)
Country | Link |
---|---|
US (1) | US6559323B1 (en) |
EP (1) | EP0983236B1 (en) |
JP (1) | JP2001527556A (en) |
KR (1) | KR20010012357A (en) |
AT (1) | ATE249431T1 (en) |
AU (1) | AU7225198A (en) |
CA (1) | CA2289755A1 (en) |
DE (1) | DE69818039T2 (en) |
ES (1) | ES2207829T3 (en) |
GB (1) | GB9709528D0 (en) |
PT (1) | PT983236E (en) |
WO (1) | WO1998051666A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6258960B1 (en) | 2000-03-17 | 2001-07-10 | Arch Development Corporation | Catalytic asymmetric synthesis of chiral aziridines |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995011230A1 (en) * | 1993-10-22 | 1995-04-27 | Zeneca Limited | Process for the preparation of an oxirane, aziridine or cyclopropane |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998030569A1 (en) | 1997-01-13 | 1998-07-16 | The Penn State Research Foundation | Asymmetric synthesis and catalysis with chiral heterocyclic compounds |
-
1997
- 1997-05-09 GB GBGB9709528.5A patent/GB9709528D0/en active Pending
-
1998
- 1998-05-01 PT PT98919377T patent/PT983236E/en unknown
- 1998-05-01 JP JP54889098A patent/JP2001527556A/en not_active Ceased
- 1998-05-01 AT AT98919377T patent/ATE249431T1/en not_active IP Right Cessation
- 1998-05-01 WO PCT/GB1998/001289 patent/WO1998051666A2/en not_active Application Discontinuation
- 1998-05-01 ES ES98919377T patent/ES2207829T3/en not_active Expired - Lifetime
- 1998-05-01 DE DE69818039T patent/DE69818039T2/en not_active Expired - Fee Related
- 1998-05-01 US US09/423,428 patent/US6559323B1/en not_active Expired - Fee Related
- 1998-05-01 KR KR1019997010309A patent/KR20010012357A/en active IP Right Grant
- 1998-05-01 EP EP98919377A patent/EP0983236B1/en not_active Expired - Lifetime
- 1998-05-01 CA CA002289755A patent/CA2289755A1/en not_active Abandoned
- 1998-05-01 AU AU72251/98A patent/AU7225198A/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995011230A1 (en) * | 1993-10-22 | 1995-04-27 | Zeneca Limited | Process for the preparation of an oxirane, aziridine or cyclopropane |
Non-Patent Citations (8)
Title |
---|
AKIO TOSHIMITSU ET AL.: "preparation of chiral Aziridines from chiral Oxiranes with retention of configuration", J. CHEM. SOC. CHEM. COMMUN., 1992, england, pages 284 - 285, XP002088748 * |
CAN. J. CHEM., vol. 59, no. 7, 1981, pages 1122 - 1131 * |
CHEMICAL ABSTRACTS, vol. 95, no. 7, 17 August 1981, Columbus, Ohio, US; abstract no. 61293f, DESLONGSCHAMPS PIERRE ET AL.: "1,7-dithia and 1-oxa-7-thiaspiro[5.5]undecanes....." page 643; column 1; XP002088751 * |
EBBE KELSTRUP: "Preparation and Conformation of some ,4-Oxathinium salts", J. CHEM. SOC.PERKIN I, 1979, england, pages 1029 - 1036, XP002088750 * |
FUMIO TODA ET AL.: "Ylide Reactions in the Solid State: a simple procedure for the Synthesis of cyclopropanes, oxiranes and aziridines.", J. CHEM. SOC. PERKIN TRANS. I, 1994, England, pages 2673 - 2674, XP002088747 * |
VARINDER K. AGGARWAL ET AL.: "Novel Catalytic and Asymmetric process for aziridination mediated by Sulfur Ylides", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 61, no. 24, 1996, columbus ohio, pages 8368 - 8369, XP002088745 * |
VARINDER K. AGGARWAL ET AL.: "Novel catalytic cycle for the Synthesis of epoxides from aldehydes and sulfur Ylides mediated by catalytic quantities of sulfides and Rh2(OAc)4", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 116, no. 13, 1994, columbus ohio, pages 5973 - 5974, XP002088746 * |
WILLIAM T. MURRAY ET AL.: "Synthesis of substituted 1,4 oxathianes.....", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 52, no. 4, 1987, columbus ohio, pages 525 - 529, XP002088749 * |
Also Published As
Publication number | Publication date |
---|---|
DE69818039T2 (en) | 2004-06-17 |
JP2001527556A (en) | 2001-12-25 |
EP0983236A2 (en) | 2000-03-08 |
WO1998051666A2 (en) | 1998-11-19 |
US6559323B1 (en) | 2003-05-06 |
DE69818039D1 (en) | 2003-10-16 |
ES2207829T3 (en) | 2004-06-01 |
PT983236E (en) | 2004-02-27 |
EP0983236B1 (en) | 2003-09-10 |
KR20010012357A (en) | 2001-02-15 |
ATE249431T1 (en) | 2003-09-15 |
CA2289755A1 (en) | 1998-11-19 |
AU7225198A (en) | 1998-12-08 |
GB9709528D0 (en) | 1997-07-02 |
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