WO1998041255A3 - Inhalation device - Google Patents

Inhalation device Download PDF

Info

Publication number
WO1998041255A3
WO1998041255A3 PCT/SE1998/000456 SE9800456W WO9841255A3 WO 1998041255 A3 WO1998041255 A3 WO 1998041255A3 SE 9800456 W SE9800456 W SE 9800456W WO 9841255 A3 WO9841255 A3 WO 9841255A3
Authority
WO
WIPO (PCT)
Prior art keywords
dispersion chamber
inhaler
housed
substance
chamber
Prior art date
Application number
PCT/SE1998/000456
Other languages
French (fr)
Other versions
WO1998041255A2 (en
Inventor
Douglas Jennings
Magnus Jeppsson
Original Assignee
Astra Ab
Douglas Jennings
Magnus Jeppsson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab, Douglas Jennings, Magnus Jeppsson filed Critical Astra Ab
Priority to JP54042298A priority Critical patent/JP2001517979A/en
Priority to EP98909945A priority patent/EP1017437A2/en
Priority to AU64302/98A priority patent/AU6430298A/en
Priority to CA002283219A priority patent/CA2283219A1/en
Publication of WO1998041255A2 publication Critical patent/WO1998041255A2/en
Publication of WO1998041255A3 publication Critical patent/WO1998041255A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0023—Mouthpieces therefor retractable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073—Syringe, piston type

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Nozzles (AREA)
  • Manipulator (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

Device for providing a substance in a dispersion chamber (5) for inhalation, includes a slip clutch (121) for driving an inhaler (10), apertures (43) in the dispersion chamber to remove settled substance, a seal (75) between a channel (67) and the dispersion chamber, an enclosed passageway extending into the dispersion chamber from which rotational drive may be taken, a portion through which an indication on a housed inhaler may be viewed, a release mechanism (143) for the piston (59) of a suction chamber (53) and a component for simultaneously operating the grip portion (71) of a housed inhaler and opening an air path in the device.
PCT/SE1998/000456 1997-03-14 1998-03-13 Inhalation device WO1998041255A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP54042298A JP2001517979A (en) 1997-03-14 1998-03-13 Inhaler
EP98909945A EP1017437A2 (en) 1997-03-14 1998-03-13 Inhalation device
AU64302/98A AU6430298A (en) 1997-03-14 1998-03-13 Inhalation device
CA002283219A CA2283219A1 (en) 1997-03-14 1998-03-13 Inhalation device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9700935A SE9700935D0 (en) 1997-03-14 1997-03-14 Inhalation device
SE9700935-1 1997-03-14

Publications (2)

Publication Number Publication Date
WO1998041255A2 WO1998041255A2 (en) 1998-09-24
WO1998041255A3 true WO1998041255A3 (en) 1999-02-18

Family

ID=20406162

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SE1998/000456 WO1998041255A2 (en) 1997-03-14 1998-03-13 Inhalation device

Country Status (6)

Country Link
EP (1) EP1017437A2 (en)
JP (1) JP2001517979A (en)
AU (1) AU6430298A (en)
CA (1) CA2283219A1 (en)
SE (1) SE9700935D0 (en)
WO (1) WO1998041255A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8950397B2 (en) 1999-07-23 2015-02-10 Mannkind Corporation Unit dose cartridge and dry powder inhaler

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US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
DE60030862T2 (en) * 1999-07-23 2007-09-06 Mannkind Corp., Valencia dry powder inhaler
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
GB0125134D0 (en) * 2001-10-19 2001-12-12 Glaxo Group Ltd Medicament dispenser
ES2300568T3 (en) 2002-03-20 2008-06-16 Mannkind Corporation INHALATION APPARATUS
CA2575692C (en) 2004-08-20 2014-10-14 Mannkind Corporation Catalysis of diketopiperazine synthesis
BR122019022692B1 (en) 2004-08-23 2023-01-10 Mannkind Corporation THERAPEUTIC DRY POWDER COMPOSITION CONTAINING DICETOPIPERAZINE, AT LEAST ONE TYPE OF CATION AND ONE BIOLOGICALLY ACTIVE AGENT
HUE028691T2 (en) 2005-09-14 2016-12-28 Mannkind Corp Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
EP1986679B1 (en) 2006-02-22 2017-10-25 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
DE102006043637A1 (en) * 2006-05-18 2007-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg atomizer
JP5092820B2 (en) 2008-03-13 2012-12-05 オムロンヘルスケア株式会社 Nebulizer and inhalation aid used therefor
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
AR072114A1 (en) 2008-06-13 2010-08-04 Mannkind Corp A DRY POWDER INHALER AND DRUG SUPPLY SYSTEM
BRPI0914308B8 (en) 2008-06-20 2021-06-22 Mannkind Corp inhalation system
TWI614024B (en) 2008-08-11 2018-02-11 曼凱公司 Use of ultrarapid acting insulin
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US8985102B2 (en) 2009-05-18 2015-03-24 Adamis Pharmaceuticals Corporation Dry powder inhalers
KR101875969B1 (en) 2009-06-12 2018-07-06 맨카인드 코포레이션 Diketopiperazine microparticles with defined specific surface areas
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
RU2571331C1 (en) 2010-06-21 2015-12-20 Маннкайнд Корпорейшн Systems and methods for dry powder drug delivery
JP6133270B2 (en) 2011-04-01 2017-05-24 マンカインド コーポレイション Blister packaging for drug cartridge
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
JP6018640B2 (en) 2011-10-24 2016-11-02 マンカインド コーポレイション Analgesic composition effective for alleviating pain, and dry powder and dry powder drug delivery system comprising the composition
SG11201500218VA (en) 2012-07-12 2015-03-30 Mannkind Corp Dry powder drug delivery systems and methods
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
WO2014144895A1 (en) 2013-03-15 2014-09-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
AU2014290438B2 (en) 2013-07-18 2019-11-07 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
WO2015021064A1 (en) 2013-08-05 2015-02-12 Mannkind Corporation Insufflation apparatus and methods
JP5990866B2 (en) * 2013-10-11 2016-09-14 株式会社リーチハイアー Oral powder inhalation aid
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler

Citations (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4099286A (en) * 1976-02-27 1978-07-11 Soji Ishikawa Cleaners for chalk erasers
GB2165159A (en) * 1984-10-04 1986-04-09 Orion Yhtymae Oy Dosing device
GB2167141A (en) * 1984-11-13 1986-05-21 Maschf Augsburg Nuernberg Ag Fluid/face - seal for shaft
WO1992004066A1 (en) * 1990-09-12 1992-03-19 Hans Bisgaard An inhaling device
WO1992004068A1 (en) * 1990-08-30 1992-03-19 Boehringer Ingelheim Kg Inhalator without propeller gas with foreign air stream
US5147971A (en) * 1990-02-28 1992-09-15 Rheinmetall Gmbh Base and obturating ring arrangement
EP0518087A1 (en) * 1991-06-14 1992-12-16 Miat S.P.A. Multi-dose insufflator for medicaments in powder form
GB2262452A (en) * 1991-12-19 1993-06-23 Minnesota Mining & Mfg Inhalation device
US5243970A (en) * 1991-04-15 1993-09-14 Schering Corporation Dosing device for administering metered amounts of powdered medicaments to patients
WO1994005357A1 (en) * 1992-09-03 1994-03-17 Maansson Sven Drug delivery system
WO1994005359A1 (en) * 1992-09-08 1994-03-17 Norton Healthcare Limited Medicament dispensing device
WO1994011044A2 (en) * 1992-11-12 1994-05-26 Minnesota Mining And Manufacturing Company Powder inhaler
WO1994017369A1 (en) * 1993-01-29 1994-08-04 Miris Medical Corporation Method and apparatus for sensing flow in two directions and automatic calibration thereof
DE4415462C1 (en) * 1994-05-03 1995-08-31 Transcoject Marketing Gmbh Inhaler for powdered medicine etc.
WO1996010708A1 (en) * 1994-10-03 1996-04-11 Duramax, Inc. Adjustable seal for propeller drive shaft
WO1996019253A1 (en) * 1994-12-21 1996-06-27 Astra Aktiebolag An inhalation device, a method of dispersing a pharmaceutically acitve substance and a method of administering a dose of a pharmaceutically active substance
WO1996022801A1 (en) * 1995-01-25 1996-08-01 Heinz Hermann Weick Pocket inhaler
WO1996039337A1 (en) * 1995-06-06 1996-12-12 Senetics, Inc. Indicator device responsive to axial force
WO1997001365A1 (en) * 1995-06-29 1997-01-16 Fisons Plc Inhalation device and method
WO1997003711A2 (en) * 1995-07-14 1997-02-06 Techbase Pty. Ltd. Spacer for aerosol medication
WO1997011732A1 (en) * 1995-09-27 1997-04-03 Astra Aktiebolag Inhalation device

Patent Citations (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4099286A (en) * 1976-02-27 1978-07-11 Soji Ishikawa Cleaners for chalk erasers
GB2165159A (en) * 1984-10-04 1986-04-09 Orion Yhtymae Oy Dosing device
GB2167141A (en) * 1984-11-13 1986-05-21 Maschf Augsburg Nuernberg Ag Fluid/face - seal for shaft
US5147971A (en) * 1990-02-28 1992-09-15 Rheinmetall Gmbh Base and obturating ring arrangement
WO1992004068A1 (en) * 1990-08-30 1992-03-19 Boehringer Ingelheim Kg Inhalator without propeller gas with foreign air stream
WO1992004066A1 (en) * 1990-09-12 1992-03-19 Hans Bisgaard An inhaling device
US5243970A (en) * 1991-04-15 1993-09-14 Schering Corporation Dosing device for administering metered amounts of powdered medicaments to patients
EP0518087A1 (en) * 1991-06-14 1992-12-16 Miat S.P.A. Multi-dose insufflator for medicaments in powder form
GB2262452A (en) * 1991-12-19 1993-06-23 Minnesota Mining & Mfg Inhalation device
WO1994005357A1 (en) * 1992-09-03 1994-03-17 Maansson Sven Drug delivery system
WO1994005359A1 (en) * 1992-09-08 1994-03-17 Norton Healthcare Limited Medicament dispensing device
WO1994011044A2 (en) * 1992-11-12 1994-05-26 Minnesota Mining And Manufacturing Company Powder inhaler
WO1994017369A1 (en) * 1993-01-29 1994-08-04 Miris Medical Corporation Method and apparatus for sensing flow in two directions and automatic calibration thereof
DE4415462C1 (en) * 1994-05-03 1995-08-31 Transcoject Marketing Gmbh Inhaler for powdered medicine etc.
WO1996010708A1 (en) * 1994-10-03 1996-04-11 Duramax, Inc. Adjustable seal for propeller drive shaft
WO1996019253A1 (en) * 1994-12-21 1996-06-27 Astra Aktiebolag An inhalation device, a method of dispersing a pharmaceutically acitve substance and a method of administering a dose of a pharmaceutically active substance
WO1996022801A1 (en) * 1995-01-25 1996-08-01 Heinz Hermann Weick Pocket inhaler
WO1996039337A1 (en) * 1995-06-06 1996-12-12 Senetics, Inc. Indicator device responsive to axial force
WO1997001365A1 (en) * 1995-06-29 1997-01-16 Fisons Plc Inhalation device and method
WO1997003711A2 (en) * 1995-07-14 1997-02-06 Techbase Pty. Ltd. Spacer for aerosol medication
WO1997011732A1 (en) * 1995-09-27 1997-04-03 Astra Aktiebolag Inhalation device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8950397B2 (en) 1999-07-23 2015-02-10 Mannkind Corporation Unit dose cartridge and dry powder inhaler

Also Published As

Publication number Publication date
JP2001517979A (en) 2001-10-09
EP1017437A2 (en) 2000-07-12
WO1998041255A2 (en) 1998-09-24
SE9700935D0 (en) 1997-03-14
CA2283219A1 (en) 1998-09-24
AU6430298A (en) 1998-10-12

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