WO1998027969A3 - Antimicrobial phenazine compounds - Google Patents
Antimicrobial phenazine compounds Download PDFInfo
- Publication number
- WO1998027969A3 WO1998027969A3 PCT/CA1997/000978 CA9700978W WO9827969A3 WO 1998027969 A3 WO1998027969 A3 WO 1998027969A3 CA 9700978 W CA9700978 W CA 9700978W WO 9827969 A3 WO9827969 A3 WO 9827969A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- phenazine
- compounds
- antimicrobial
- phenazine compounds
- growth
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU54719/98A AU5471998A (en) | 1996-12-24 | 1997-12-24 | Antimicrobial phenazine compounds |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3403596P | 1996-12-24 | 1996-12-24 | |
US60/034,035 | 1996-12-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998027969A2 WO1998027969A2 (en) | 1998-07-02 |
WO1998027969A3 true WO1998027969A3 (en) | 1998-10-01 |
Family
ID=21873904
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CA1997/000978 WO1998027969A2 (en) | 1996-12-24 | 1997-12-24 | Antimicrobial phenazine compounds |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU5471998A (en) |
CA (1) | CA2247348A1 (en) |
WO (1) | WO1998027969A2 (en) |
Citations (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1103137A (en) * | 1965-10-22 | 1968-02-14 | Pfizer & Co C | 1,2,3,4-tetrahydrophenazine-5,10-dioxides, and derivatives thereof useful in veterinary applications |
GB1182617A (en) * | 1967-06-09 | 1970-02-25 | Shell Int Research | Phenazine di-N-Oxides and Compositions containing them |
US3530130A (en) * | 1967-09-14 | 1970-09-22 | Hoffmann La Roche | 1-acylated-6-methoxyphenazine 5,10-dioxides |
US3567728A (en) * | 1968-07-05 | 1971-03-02 | Pfizer | Process for the preparation of phenazine di-n-oxides and related compounds |
DE1695429A1 (en) * | 1967-06-08 | 1971-04-15 | Merck Patent Gmbh | Process for the preparation of 1-methoxyphenazine-5,10-dioxide |
US3586674A (en) * | 1969-04-08 | 1971-06-22 | Hoffmann La Roche | Organometallic derivatives of 6-lower alkoxy 1-phenazinol 5,10-dioxide |
US3609153A (en) * | 1967-04-20 | 1971-09-28 | Canadian Patents Dev | 1 hydroxy 6 methoxy phenazines |
GB1271194A (en) * | 1970-04-03 | 1972-04-19 | Pfizer | PREPARATION OF QUINOXALINE-DI-N-OXIDES FROM o-QUINONEDIOXIME AND BUTENE-1,4 DIONES |
US3678051A (en) * | 1970-04-02 | 1972-07-18 | Hoffmann La Roche | Derivatives of 1,6-phenazinediol 5,10-dioxide |
GB1285010A (en) * | 1970-04-02 | 1972-08-09 | Hoffmann La Roche | Phenazine derivatives and a process for the manufacture thereof |
US3700679A (en) * | 1970-06-08 | 1972-10-24 | Hoffmann La Roche | Nuclear substituted derivatives of 1-hydroxy-6-methoxyphenazine 5,10-dioxide |
FR2134012A1 (en) * | 1971-04-23 | 1972-12-01 | Hoffmann La Roche | Myxin-metal complexes prodn - by reaction in aq suspension, having broad-sprectum antimicrobial activity |
US3822265A (en) * | 1966-11-25 | 1974-07-02 | Hoffmann La Roche | Phenazine derivatives |
US3937707A (en) * | 1972-05-01 | 1976-02-10 | Hoffmann-La Roche Inc. | 6-substituted 1-phenazinol 5,10-dioxide derivatives |
US3985734A (en) * | 1971-04-23 | 1976-10-12 | Hoffmann-La Roche Inc. | Method for the preparation of the copper complex of 6-methoxy-1-phenazinol 5,10-dioxide |
US5637591A (en) * | 1995-06-02 | 1997-06-10 | Fuji Immunopharmaceuticals Corp. | Antimicrobial and anticollagenase activity of phenazine-5, 10-dioxide and derivatives |
-
1997
- 1997-12-24 WO PCT/CA1997/000978 patent/WO1998027969A2/en active Application Filing
- 1997-12-24 AU AU54719/98A patent/AU5471998A/en not_active Abandoned
- 1997-12-24 CA CA002247348A patent/CA2247348A1/en not_active Abandoned
Patent Citations (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1103137A (en) * | 1965-10-22 | 1968-02-14 | Pfizer & Co C | 1,2,3,4-tetrahydrophenazine-5,10-dioxides, and derivatives thereof useful in veterinary applications |
US3822265A (en) * | 1966-11-25 | 1974-07-02 | Hoffmann La Roche | Phenazine derivatives |
US3609153A (en) * | 1967-04-20 | 1971-09-28 | Canadian Patents Dev | 1 hydroxy 6 methoxy phenazines |
DE1695429A1 (en) * | 1967-06-08 | 1971-04-15 | Merck Patent Gmbh | Process for the preparation of 1-methoxyphenazine-5,10-dioxide |
GB1182617A (en) * | 1967-06-09 | 1970-02-25 | Shell Int Research | Phenazine di-N-Oxides and Compositions containing them |
US3530130A (en) * | 1967-09-14 | 1970-09-22 | Hoffmann La Roche | 1-acylated-6-methoxyphenazine 5,10-dioxides |
US3567728A (en) * | 1968-07-05 | 1971-03-02 | Pfizer | Process for the preparation of phenazine di-n-oxides and related compounds |
US3586674A (en) * | 1969-04-08 | 1971-06-22 | Hoffmann La Roche | Organometallic derivatives of 6-lower alkoxy 1-phenazinol 5,10-dioxide |
US3678051A (en) * | 1970-04-02 | 1972-07-18 | Hoffmann La Roche | Derivatives of 1,6-phenazinediol 5,10-dioxide |
GB1285010A (en) * | 1970-04-02 | 1972-08-09 | Hoffmann La Roche | Phenazine derivatives and a process for the manufacture thereof |
GB1271194A (en) * | 1970-04-03 | 1972-04-19 | Pfizer | PREPARATION OF QUINOXALINE-DI-N-OXIDES FROM o-QUINONEDIOXIME AND BUTENE-1,4 DIONES |
US3700679A (en) * | 1970-06-08 | 1972-10-24 | Hoffmann La Roche | Nuclear substituted derivatives of 1-hydroxy-6-methoxyphenazine 5,10-dioxide |
FR2134012A1 (en) * | 1971-04-23 | 1972-12-01 | Hoffmann La Roche | Myxin-metal complexes prodn - by reaction in aq suspension, having broad-sprectum antimicrobial activity |
US3985734A (en) * | 1971-04-23 | 1976-10-12 | Hoffmann-La Roche Inc. | Method for the preparation of the copper complex of 6-methoxy-1-phenazinol 5,10-dioxide |
US3937707A (en) * | 1972-05-01 | 1976-02-10 | Hoffmann-La Roche Inc. | 6-substituted 1-phenazinol 5,10-dioxide derivatives |
US5637591A (en) * | 1995-06-02 | 1997-06-10 | Fuji Immunopharmaceuticals Corp. | Antimicrobial and anticollagenase activity of phenazine-5, 10-dioxide and derivatives |
Non-Patent Citations (6)
Title |
---|
GRUNBERG ET AL.: "Studies on the in vitro and in vivo chemotherapeutic properties of the antibiotic Myxin", CHEMOTHERAPIA, vol. 12, no. 5, 1967, pages 272 - 281, XP002062758 * |
MAESTRONE ET AL.: "Chemotherapeutic activity of 6-methoxy-1-phenazinol 5,10-dioxide, cupric complex in experimentally induced local microbial infections in dogs", AM. J. VET. RES., vol. 35, no. 2, 1974, pages 281 - 284, XP002062759 * |
MAESTRONE ET AL.: "Topical antimicrobial activity of 6-Methoxy-1-Phenazinol 5,10-dioxide, cupric complex", AM. J. VET. RES., vol. 33, no. 1, 1972, pages 185 - 193, XP002062754 * |
MAESTRONE TE AL.: "Evaluation of Cuprimyxin-hydrocortisone acetate suspension in the treatment of otitis externa in dogs and cats", AM. J. VET. RES., vol. 40, no. 2, 1979, pages 285 - 287, XP002062755 * |
MCDONALD ET AL.: "Antimicrobial susceptibility of Prototheca zopfii isolated from bovine intramammary infections", AM. J. VET. RES., vol. 45, no. 6, 1984, pages 1079- - 1080, XP002062756 * |
SEKHON ET AL.: "Sensitivity of some human pathogenic yeasts and systemic fungi to myxin", ABSTR. ANNU. MEET. AM. SOC. MICROBIOL., vol. 75, 1975, pages 44, XP002062757 * |
Also Published As
Publication number | Publication date |
---|---|
WO1998027969A2 (en) | 1998-07-02 |
CA2247348A1 (en) | 1998-07-02 |
AU5471998A (en) | 1998-07-17 |
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