WO1998025655A3 - Method and apparatus for administration of substances by ultrasound - Google Patents

Method and apparatus for administration of substances by ultrasound

Info

Publication number
WO1998025655A3
WO1998025655A3 PCT/IL1997/000405 IL9700405W WO9825655A3 WO 1998025655 A3 WO1998025655 A3 WO 1998025655A3 IL 9700405 W IL9700405 W IL 9700405W WO 9825655 A3 WO9825655 A3 WO 9825655A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
substances
administration
method
ultrasound
apparatus
Prior art date
Application number
PCT/IL1997/000405
Other languages
French (fr)
Other versions
WO1998025655A2 (en )
Inventor
Yoni Iger
Eitan Kimmel
Original Assignee
Technion Res & Dev Foundation
Yoni Iger
Eitan Kimmel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation; Therapies using these preparations
    • A61K41/0047Sonopheresis, i.e. ultrasonically-enhanced transdermal delivery, electroporation of a pharmacologically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis

Abstract

The invention concerns a method for administration of substances to or through cells, tissues or membranes by exposing the cells, tissues or membranes to two ultrasound stimuli wherein the first stimulus is used to create transient openings in the cells, tissues or membranes and the second stimulus is used in driving the substances through said openings.
PCT/IL1997/000405 1996-12-13 1997-12-12 Method and apparatus for administration of substances by ultrasound WO1998025655A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL119827 1996-12-13
IL11982796 1996-12-13

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA 2274690 CA2274690A1 (en) 1996-12-13 1997-12-12 Method and apparatus for administration of substances by ultrasound
JP52643998A JP2001506880A (en) 1996-12-13 1997-12-12 Method and apparatus for administering a substance by ultrasonic
EP19970947208 EP0989825A2 (en) 1996-12-13 1997-12-12 Method and apparatus for administration of substances by ultrasound

Publications (2)

Publication Number Publication Date
WO1998025655A2 true WO1998025655A2 (en) 1998-06-18
WO1998025655A3 true true WO1998025655A3 (en) 1998-08-13

Family

ID=11069580

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL1997/000405 WO1998025655A3 (en) 1996-12-13 1997-12-12 Method and apparatus for administration of substances by ultrasound

Country Status (4)

Country Link
EP (1) EP0989825A2 (en)
JP (1) JP2001506880A (en)
CA (1) CA2274690A1 (en)
WO (1) WO1998025655A3 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9398894B2 (en) 2007-12-21 2016-07-26 Carticept Medical, Inc. Removable cassette for articular injection system

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0422525D0 (en) * 2004-10-11 2004-11-10 Luebcke Peter Dermatological compositions and methods
JP4921795B2 (en) * 2006-01-06 2012-04-25 東芝メディカルシステムズ株式会社 Ultrasonic drug introducing apparatus and a medical image diagnostic apparatus
US8545440B2 (en) 2007-12-21 2013-10-01 Carticept Medical, Inc. Injection system for delivering multiple fluids within the anatomy
US9044542B2 (en) 2007-12-21 2015-06-02 Carticept Medical, Inc. Imaging-guided anesthesia injection systems and methods

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5267985A (en) * 1993-02-11 1993-12-07 Trancell, Inc. Drug delivery by multiple frequency phonophoresis
US5505726A (en) * 1994-03-21 1996-04-09 Dusa Pharmaceuticals, Inc. Article of manufacture for the photodynamic therapy of dermal lesion
US5618275A (en) * 1995-10-27 1997-04-08 Sonex International Corporation Ultrasonic method and apparatus for cosmetic and dermatological applications

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5267985A (en) * 1993-02-11 1993-12-07 Trancell, Inc. Drug delivery by multiple frequency phonophoresis
US5505726A (en) * 1994-03-21 1996-04-09 Dusa Pharmaceuticals, Inc. Article of manufacture for the photodynamic therapy of dermal lesion
US5618275A (en) * 1995-10-27 1997-04-08 Sonex International Corporation Ultrasonic method and apparatus for cosmetic and dermatological applications

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9398894B2 (en) 2007-12-21 2016-07-26 Carticept Medical, Inc. Removable cassette for articular injection system

Also Published As

Publication number Publication date Type
EP0989825A2 (en) 2000-04-05 application
CA2274690A1 (en) 1998-06-18 application
JP2001506880A (en) 2001-05-29 application
WO1998025655A2 (en) 1998-06-18 application

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