WO1998021332A3 - Secreted proteins and polynucleotides encoding them - Google Patents

Secreted proteins and polynucleotides encoding them Download PDF

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Publication number
WO1998021332A3
WO1998021332A3 PCT/US1997/020740 US9720740W WO9821332A3 WO 1998021332 A3 WO1998021332 A3 WO 1998021332A3 US 9720740 W US9720740 W US 9720740W WO 9821332 A3 WO9821332 A3 WO 9821332A3
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WO
WIPO (PCT)
Prior art keywords
polynucleotides encoding
secreted proteins
proteins
secreted
polynucleotides
Prior art date
Application number
PCT/US1997/020740
Other languages
French (fr)
Other versions
WO1998021332A2 (en
Inventor
Kenneth Jacobs
John M Mccoy
Edward R Lavallie
Lisa A Racie
David Merberg
Maurice Treacy
Vikki Spaulding
Michael J Agostino
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst filed Critical Genetics Inst
Priority to JP52282098A priority Critical patent/JP2002514058A/en
Priority to AU52562/98A priority patent/AU5256298A/en
Priority to EP97947497A priority patent/EP0942974A2/en
Priority to CA002270873A priority patent/CA2270873A1/en
Publication of WO1998021332A2 publication Critical patent/WO1998021332A2/en
Publication of WO1998021332A3 publication Critical patent/WO1998021332A3/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Abstract

Novel polynucleotides and the proteins encoded thereby are disclosed.
PCT/US1997/020740 1996-11-15 1997-11-14 Secreted proteins and polynucleotides encoding them WO1998021332A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP52282098A JP2002514058A (en) 1996-11-15 1997-11-14 Secreted proteins and polynucleotides encoding them
AU52562/98A AU5256298A (en) 1996-11-15 1997-11-14 Secreted proteins and polynucleotides encoding them
EP97947497A EP0942974A2 (en) 1996-11-15 1997-11-14 Secreted proteins and polynucleotides encoding them
CA002270873A CA2270873A1 (en) 1996-11-15 1997-11-14 Secreted proteins and polynucleotides encoding them

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US74974596A 1996-11-15 1996-11-15
US08/749,745 1996-11-15
US86767897A 1997-06-02 1997-06-02
US08/867,678 1997-06-02
US96951597A 1997-11-13 1997-11-13
US08/969,515 1997-11-13

Publications (2)

Publication Number Publication Date
WO1998021332A2 WO1998021332A2 (en) 1998-05-22
WO1998021332A3 true WO1998021332A3 (en) 1998-08-06

Family

ID=27419386

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/020740 WO1998021332A2 (en) 1996-11-15 1997-11-14 Secreted proteins and polynucleotides encoding them

Country Status (5)

Country Link
EP (1) EP0942974A2 (en)
JP (1) JP2002514058A (en)
AU (1) AU5256298A (en)
CA (1) CA2270873A1 (en)
WO (1) WO1998021332A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE402953T1 (en) * 1999-10-18 2008-08-15 Lexicon Pharmaceuticals Inc HUMAN CHORDIN AND POLYNUCLEOTIDES THAT CODE FOR IT
US6929923B2 (en) * 2002-07-23 2005-08-16 Rigel Pharmaceuticals, Inc. Modulators of leukocyte activation, BIC compositions and methods of use
CA2568886A1 (en) 2004-07-02 2006-02-09 Genentech, Inc. Compositions and methods for treatment of non-hodgkin's lymphoma
JP2008289363A (en) * 2005-09-05 2008-12-04 National Institutes Of Natural Sciences Protein constituting voltage-activated type proton channel and method for utilizing the same

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990005780A1 (en) * 1988-11-18 1990-05-31 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University Dopamine receptors and genes
WO1990014432A1 (en) * 1989-05-23 1990-11-29 Genetics Institute, Inc. A human cytokine, interleukin-9
EP0510691A1 (en) * 1991-04-26 1992-10-28 Osaka Bioscience Institute DNA coding for human cell surface antigen
WO1994007916A1 (en) * 1992-10-07 1994-04-14 Merck & Co., Inc. Human steroid hormone receptor neri
WO1996017925A1 (en) * 1994-12-06 1996-06-13 Immunex Corporation Cytokine designated lerk-7
US5536637A (en) * 1993-04-07 1996-07-16 Genetics Institute, Inc. Method of screening for cDNA encoding novel secreted mammalian proteins in yeast
WO1997007198A2 (en) * 1995-08-11 1997-02-27 Genetics Institute, Inc. Dna sequences and secreted proteins encoded thereby
WO1997025427A1 (en) * 1996-01-12 1997-07-17 Genetics Institute, Inc. Beta-chemokine, h1305 (mcp-2)

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990005780A1 (en) * 1988-11-18 1990-05-31 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University Dopamine receptors and genes
WO1990014432A1 (en) * 1989-05-23 1990-11-29 Genetics Institute, Inc. A human cytokine, interleukin-9
EP0510691A1 (en) * 1991-04-26 1992-10-28 Osaka Bioscience Institute DNA coding for human cell surface antigen
WO1994007916A1 (en) * 1992-10-07 1994-04-14 Merck & Co., Inc. Human steroid hormone receptor neri
US5536637A (en) * 1993-04-07 1996-07-16 Genetics Institute, Inc. Method of screening for cDNA encoding novel secreted mammalian proteins in yeast
WO1996017925A1 (en) * 1994-12-06 1996-06-13 Immunex Corporation Cytokine designated lerk-7
WO1997007198A2 (en) * 1995-08-11 1997-02-27 Genetics Institute, Inc. Dna sequences and secreted proteins encoded thereby
WO1997025427A1 (en) * 1996-01-12 1997-07-17 Genetics Institute, Inc. Beta-chemokine, h1305 (mcp-2)

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ADAMS M D ET AL: "3,400 NEW EXPRESSED SEQUENCE TAGS IDENTIFY DIVERSITY OF TRANSCRIPTS IN HUMAN BRAIN", NATURE GENETICS, vol. 4, no. 3, pages 256 - 267, XP000611495 *
JACOBS K ET AL: "A novel method for isolating eukaryotic cDNA clones encoding secreted proteins.", KEYSTONE SYMPOSIUM ON DENDRITIC CELLS: ANTIGEN PRESENTING CELLS OF T AND B LYMPHOCYTES, TAOS, NEW MEXICO, USA, MARCH 10-16, 1995. JOURNAL OF CELLULAR BIOCHEMISTRY SUPPLEMENT 0 (21A). 1995. 19. ISSN: 0733-1959, XP002027246 *
R.J. KAUFMAN ET AL.: "Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in chinese hamster ovary cells", MOL. CELL. BIOL., vol. 9, no. 3, March 1989 (1989-03-01), ASM WASHINGTON, DC,US, pages 1233 - 1242, XP002041592 *
R.J. KAUFMAN ET AL.: "Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus", NUCLEIC ACIDS RESEARCH, vol. 19, no. 16, 1991, IRL PRESS LIMITED,OXFORD,ENGLAND, pages 4485 - 4490, XP002041594 *
R.J. KAUFMAN ET AL.: "The phosphorylation state of eucaryotic initiation factor 2 alters translation efficiency of specific mRNAs", MOL. CELL. BIOL., vol. 9, no. 3, March 1989 (1989-03-01), ASM WASHINGTON, DC,US, pages 946 - 958, XP002041593 *

Also Published As

Publication number Publication date
CA2270873A1 (en) 1998-05-22
AU5256298A (en) 1998-06-03
EP0942974A2 (en) 1999-09-22
JP2002514058A (en) 2002-05-14
WO1998021332A2 (en) 1998-05-22

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