WO1998013500A3 - Recombinant mva virus expressing dengue virus antigens, and the use thereof in vaccines - Google Patents
Recombinant mva virus expressing dengue virus antigens, and the use thereof in vaccines Download PDFInfo
- Publication number
- WO1998013500A3 WO1998013500A3 PCT/EP1997/005214 EP9705214W WO9813500A3 WO 1998013500 A3 WO1998013500 A3 WO 1998013500A3 EP 9705214 W EP9705214 W EP 9705214W WO 9813500 A3 WO9813500 A3 WO 9813500A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- recombinant mva
- vaccines
- antigens
- dengue virus
- expressing dengue
- Prior art date
Links
- 241000725619 Dengue virus Species 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 238000002255 vaccination Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU45565/97A AU4556597A (en) | 1996-09-24 | 1997-09-23 | Recombinant mva virus expressing dengue virus antigens, and the use thereof in vaccines |
US09/147,919 US6869793B2 (en) | 1996-09-24 | 1997-09-23 | Recombinant MVA virus expressing dengue virus antigens, and the use thereof in vaccines |
EP97943887A EP0951555A2 (en) | 1996-09-24 | 1997-09-23 | Recombinant mva virus expressing dengue virus antigens, and the use thereof in vaccines |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK103596 | 1996-09-24 | ||
DK1035/96 | 1996-09-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998013500A2 WO1998013500A2 (en) | 1998-04-02 |
WO1998013500A3 true WO1998013500A3 (en) | 1998-06-18 |
Family
ID=8100273
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1997/005214 WO1998013500A2 (en) | 1996-09-24 | 1997-09-23 | Recombinant mva virus expressing dengue virus antigens, and the use thereof in vaccines |
Country Status (6)
Country | Link |
---|---|
US (1) | US6869793B2 (en) |
EP (1) | EP0951555A2 (en) |
AU (1) | AU4556597A (en) |
ID (1) | ID19548A (en) |
MY (1) | MY150893A (en) |
WO (1) | WO1998013500A2 (en) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999015692A2 (en) * | 1997-09-23 | 1999-04-01 | Bavarian Nordic Research Institute A/S | Dengue virus antigens and treatment of dengue fever |
US6582693B2 (en) | 1998-11-30 | 2003-06-24 | Lemery, S.A. De C.V. | Recombinant MVA virus expressing the E2 gene of Bovine papillomavirus and its use in the therapy of tumors generated by papillomaviruses |
US20040265324A1 (en) * | 1999-03-23 | 2004-12-30 | Cardosa Mary Jane | Recombinant MVA virus expressing dengue virus antigens, and the use thereof in vaccines |
US6682742B1 (en) | 1999-05-28 | 2004-01-27 | Gsf Forschungszentrum Fur Unwelt Und Gesundheit Gmbh | Vector for integration of heterologous sequences into poxviral genomes |
NZ524661A (en) * | 2000-11-23 | 2005-03-24 | Bavarian Nordic As | Modified vaccinia ankara virus variant |
US7628980B2 (en) | 2000-11-23 | 2009-12-08 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
CA2466413C (en) * | 2001-12-04 | 2014-11-04 | Bavarian Nordic A/S | Flavivirus ns1 subunit vaccine |
NZ533302A (en) * | 2001-12-10 | 2005-11-25 | Bavarian Nordic As | Poxvirus containing formulations and process for preparing stable, poxvirus containing compositions containing a disaaccharide and a pharmaceutically acceptable polymer i.e. dextran or polyvinylpyrrolidon (PVP) |
NZ533586A (en) | 2001-12-20 | 2005-02-25 | Bavarian Nordic As | Method for the recovery and purification of poxviruses from infected cells using high pressure homogenisation |
EP1839672A3 (en) * | 2002-04-19 | 2007-11-21 | Bavarian Nordic A/S | Modified vaccinia virus Ankara for the vaccination of neonates |
EA007811B1 (en) | 2002-05-16 | 2007-02-27 | Бавариан Нордик А/С | Intergenic regions as insertion sites in the genome of modified vaccine virus ankara (mva) |
EA009525B1 (en) * | 2002-05-16 | 2008-02-28 | Бавариан Нордик А/С | Recombinant modified vaccinia virus ankara comprising the cowpox ati promoter and methods of use virus and promoter |
ATE504653T1 (en) | 2002-08-07 | 2011-04-15 | Bavarian Nordic As | VACCINIA VIRUS HOST SPECTRUM GENES FOR INCREASING THE TITRE OF AVIPOXVIRUSES |
KR101044538B1 (en) | 2002-09-05 | 2011-06-27 | 버베리안 노딕 에이/에스 | Method for the cultivation of primary cells and for the amplification of viruses under serum free conditions |
PT1567653E (en) * | 2002-11-25 | 2007-10-01 | Bavarian Nordic As | Recombinant poxvirus comprising at least two cowpox ati promoters |
CA2432738A1 (en) | 2003-02-26 | 2004-08-26 | Philippe Despres | New dengue and west nile viruses proteins and genes coding the foregoing, and their use in vaccinal, therapeutic and diagnostic applications |
CA2576798C (en) * | 2004-07-27 | 2014-09-09 | Gwong-Jen J. Chang | Localization and characterization of flavivirus envelope glycoprotein cross-reactive epitopes and methods for their use |
SG10201912554TA (en) | 2005-03-23 | 2020-02-27 | Genmab As | Antibodies against cd38 for treatment of multiple myeloma |
WO2006113927A2 (en) * | 2005-04-20 | 2006-10-26 | University Of Washington | Immunogenic vaccinia peptides and methods of using same |
CU23586A1 (en) | 2005-11-22 | 2010-10-30 | Ct Ingenieria Genetica Biotech | METHODS AND PROTEINS FOR THE PROPHLACTIC AND / OR THERAPEUTIC TREATMENT OF THE FOUR SEROTYPES OF THE DENGUE VIRUS AND OTHER FLAVIVIRUS |
US7913477B2 (en) * | 2006-01-27 | 2011-03-29 | William Anthony Harper | Insert registration in packets |
US8115285B2 (en) * | 2008-03-14 | 2012-02-14 | Advanced Semiconductor Engineering, Inc. | Advanced quad flat no lead chip package having a protective layer to enhance surface mounting and manufacturing methods thereof |
NZ593415A (en) * | 2008-12-05 | 2014-04-30 | Inviragen Inc | Compositions, methods and uses for inducing viral growth |
FR3042121A1 (en) | 2015-10-08 | 2017-04-14 | Jean-Marc Limacher | ANTI-TUMOR COMPOSITION |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990001946A1 (en) * | 1988-08-20 | 1990-03-08 | The United States Of America, Represented By The Secretary, United States Department Of Commerce | Recombinant vaccinia virus for prevention of disease caused by flavivirus |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1341245C (en) * | 1988-01-12 | 2001-06-05 | F. Hoffmann-La Roche Ag | Recombinant vaccinia virus mva |
MY109299A (en) * | 1990-08-15 | 1996-12-31 | Virogenetics Corp | Recombinant pox virus encoding flaviviral structural proteins |
US5514375A (en) * | 1990-08-15 | 1996-05-07 | Virogenetics Corporation | Flavivirus recombinant poxvirus vaccine |
US5494671A (en) * | 1990-08-27 | 1996-02-27 | The United States Of America As Represented By The Department Of Health And Human Services | C-terminally truncated dengue and Japanese encephalitis virus envelope proteins |
EP0575491B1 (en) * | 1991-03-07 | 2003-08-13 | Virogenetics Corporation | Genetically engineered vaccine strain |
GB9105383D0 (en) * | 1991-03-14 | 1991-05-01 | Immunology Ltd | An immunotherapeutic for cervical cancer |
US5369025A (en) * | 1991-06-28 | 1994-11-29 | The United States Of America As Represented By The Secretary Of Agriculture | Recombinant fowlpox vaccine for protection against Marek's disease |
UA68327C2 (en) | 1995-07-04 | 2004-08-16 | Gsf Forschungszentrum Fur Unwe | A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals |
US6074865A (en) * | 1995-07-20 | 2000-06-13 | The United States Of America As Represented By The Secretary Of The Army | Recombinant dengue virus DNA fragment |
-
1997
- 1997-09-23 AU AU45565/97A patent/AU4556597A/en not_active Abandoned
- 1997-09-23 EP EP97943887A patent/EP0951555A2/en not_active Withdrawn
- 1997-09-23 WO PCT/EP1997/005214 patent/WO1998013500A2/en active Application Filing
- 1997-09-23 ID IDP973270A patent/ID19548A/en unknown
- 1997-09-23 US US09/147,919 patent/US6869793B2/en not_active Expired - Fee Related
- 1997-09-23 MY MYPI0804193 patent/MY150893A/en unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990001946A1 (en) * | 1988-08-20 | 1990-03-08 | The United States Of America, Represented By The Secretary, United States Department Of Commerce | Recombinant vaccinia virus for prevention of disease caused by flavivirus |
Non-Patent Citations (3)
Title |
---|
G SUTTER AND B MOSS: "Novel vaccinia vector derived from the host range restricted and highly attenuated MVA strain of vaccinia virus", DEVELOPMENTS IN BIOLOGICAL STANDARDIZATION, vol. 84, 1995, pages 195 - 200, XP000611390 * |
V F YAMSHCHIKOV ET AL: "Generation of long flavivirus expression cassettes by in vivo recombination and transient dominant selection", GENE, vol. 149, 1994, pages 193 - 201, XP000606301 * |
V M HIRSCH ET AL: "Limited virus replication following SIV challenge of macaques immunized with attenuated MVA vaccinia expressing SIVsm env and gag-pol", VACCINES 95 MODERN APPROACHES TO NEW VACCINES, vol. 95, 1995, pages 195 - 200, XP000610097 * |
Also Published As
Publication number | Publication date |
---|---|
ID19548A (en) | 1998-07-23 |
WO1998013500A2 (en) | 1998-04-02 |
AU4556597A (en) | 1998-04-17 |
US6869793B2 (en) | 2005-03-22 |
US20030082205A1 (en) | 2003-05-01 |
EP0951555A2 (en) | 1999-10-27 |
MY150893A (en) | 2014-03-14 |
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